Standout Papers
Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
Preferential Generation of Follicular B Helper T Cells from Foxp3 + T Cells in Gut Peyer's Patches
2009 StandoutScienceNobel
Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8 + T cells
2005
A Tlr7 translocation accelerates systemic autoimmunity in murine lupus
2006
Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus
2009 StandoutNobel
The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic T reg Cell Homeostasis
2013 StandoutScience
Trans-Endocytosis of CD80 and CD86: A Molecular Basis for the Cell-Extrinsic Function of CTLA-4
2011 Science
A sex-biased imbalance between Tfr, Tph, and atypical B cells determines antibody responses in COVID-19 patients
2023 StandoutNobel
Selective delivery of β cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8 + T cells in NOD mice
2008 StandoutNobel
Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species
2010 StandoutScience
Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression
2013 StandoutNobel
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses
2007
CD4+ regulatory T cells require CTLA-4 for the maintenance of systemic tolerance
2009
Early growth response gene 2 (Egr-2) controls the self-tolerance of T cells and prevents the development of lupuslike autoimmune disease
2008
Spontaneous Large-Scale Lymphoid Neogenesis and Balanced Autoimmunity versus Tolerance in the Stomach of H+/K+-ATPase-Reactive TCR Transgenic Mouse
2006 StandoutNobel
Differential Development of Murine Dendritic Cells by GM-CSF versus Flt3 Ligand Has Implications for Inflammation and Trafficking
2007
Confusing signals: Recent progress in CTLA-4 biology
2015
Interleukin 10 (IL-10): an immunosuppressive factor and independent predictor in patients with metastatic renal cell carcinoma
1999
Tumour escape from immune surveillance through dendritic cell inactivation
2002
The Lupus-Related Lmb3 Locus Contains a Disease-Suppressing Coronin-1A Gene Mutation
2008
Psoriasis
2009 Standout
Intestinal Microbial Diversity during Early-Life Colonization Shapes Long-Term IgE Levels
2013
Fatal Autoimmune Hepatitis Induced by Concurrent Loss of Naturally Arising Regulatory T Cells and PD-1-Mediated Signaling
2008 StandoutNobel
Infliximab induction and maintenance therapy for moderate-to-severe psoriasis: a phase III, multicentre, double-blind trial
2005
Pathogenic role for skin macrophages in a mouse model of keratinocyte-induced psoriasis-like skin inflammation
2006
Inability of a Fusion Protein of IL-2 and Diphtheria Toxin (Denileukin Diftitox, DAB389IL-2, ONTAK) to Eliminate Regulatory T Lymphocytes in Patients With Melanoma
2005
Mapping of the human IL10 gene and further characterization of the 5' flanking sequence
1997
Treg and CTLA-4: Two intertwining pathways to immune tolerance
2013
Dendritic cells as mediators of tumor-induced tolerance in metastatic melanoma
1997
Interleukin-10 is a growth factor for human melanoma cells and down-regulates HLA class-I, HLA class-II and ICAM-1 molecules
1997
Pathogenesis and therapy of psoriasis
2007 StandoutNature
Dermatologist-level classification of skin cancer with deep neural networks
2017 StandoutNature
A new mathematical model for relative quantification in real-time RT-PCR
2001 Standout
Traditional systemic treatments have not fully met the needs of psoriasis patients: Results from a national survey
2005
Dendritic cells: versatile controllers of the immune system
2007 StandoutNobel
Cell-autonomous and -non-autonomous roles of CTLA-4 in immune regulation
2011 StandoutNobel
The pathogenic role of tissue-resident immune cells in psoriasis
2007
Diagnostic accuracy of dermoscopy
2002
Psoriasis pathogenesis and the development of novel targeted immune therapies
2017
Microbial Stimulation Fully Differentiates Monocytes to DC-SIGN/CD209+ Dendritic Cells for Immune T Cell Areas
2010 StandoutNobel
Recent insights into the immunopathogenesis of psoriasis provide new therapeutic opportunities
2004
Psoriasis: emerging therapeutic strategies
2005
Adoptive cell transfer: a clinical path to effective cancer immunotherapy
2008
The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses
2011
Principles of adoptive T cell cancer therapy
2007
Immunity, Inflammation, and Cancer
2010 Standout
Cellular Genomic Maps Help Dissect Pathology in Human Skin Disease
2007
The long-term efficacy and safety of new biological therapies for psoriasis
2006
Prominent Production of IL-20 by CD68+/CD11c+ Myeloid-Derived Cells in Psoriasis: Gene Regulation and Cellular Effects
2006
Taking dendritic cells into medicine
2007 StandoutNatureNobel
T cell homeostasis: Keeping useful T cells alive and live T cells useful
2005
Oral pimecrolimus in the treatment of moderate to severe chronic plaque-type psoriasis: a double-blind, multicentre, randomized, dose-finding trial
2005
Psoriasis: genetic associations and immune system changes
2006
Innate and adaptive immunity and the pathophysiology of psoriasis
2006
Cancer immunotherapy comes of age
2011 StandoutNature
Activation-Induced Cytidine Deaminase Expression in CD4+ T Cells is Associated with a Unique IL-10-Producing Subset that Increases with Age
2011 StandoutNobel
Regulation of Tumor Growth and Metastasis by Interleukin-10: The Melanoma Experience
1999
The gut microbiota — masters of host development and physiology
2013 Standout
Positive and negative influences of regulatory T cells on tumour immunity
2008
Psoriasis
2005
Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade
2017 StandoutNobel
Dendritic cells and the control of immunity
1998 StandoutNatureNobel
Generation of large numbers of fully mature and stable dendritic cells from leukapheresis products for clinical application
1999
A Phase I Study Evaluating the Safety, Pharmacokinetics, and Clinical Response of a Human IL-12 p40 Antibody in Subjects with Plaque Psoriasis
2004
Efficacy and safety results from the randomized controlled comparative study of adalimumab vs. methotrexate vs. placebo in patients with psoriasis (CHAMPION)
2007
Protein therapeutics: a summary and pharmacological classification
2007 Standout
Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model
2004
Gut flora antigens are not important in the maintenance of regulatory T cell heterogeneity and homeostasis
2007
Genetics of autoimmune diseases in humans and in animal models
2002
Homeostatic Expansion of T Cells during Immune Insufficiency Generates Autoimmunity
2004
Synergistic Reversal of Intrahepatic HCV-Specific CD8 T Cell Exhaustion by Combined PD-1/CTLA-4 Blockade
2009
Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
2006 StandoutNature
Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays
2000 Standout
Establishment of NOD-Pdcd1-/-mice as an efficient animal model of type I diabetes
2005 StandoutNobel
Recent insights into the immunopathogenesis of psoriasis provide new therapeutic opportunities
2004
Demystifying the development of dendritic cell subtypes, a little
2008
Interleukin-10–Treated Human Dendritic Cells Induce a Melanoma-Antigen–Specific Anergy in CD8+ T Cells Resulting in a Failure to Lyse Tumor Cells
1999
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
Serum Interleukin-10 Levels as a Prognostic Factor in Advanced Non-small Cell Lung Cancer Patients
2000
CD4+CD25−LAG3+regulatory T cells controlled by the transcription factor Egr-2
2009 StandoutNobel
Vaccination with Mage-3a1 Peptide–Pulsed Mature, Monocyte-Derived Dendritic Cells Expands Specific Cytotoxic T Cells and Induces Regression of Some Metastases in Advanced Stage IV Melanoma
1999 StandoutNobel
Type I IFN Protects Against Murine Lupus
2004
Nonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model
2016 StandoutNobel
Interactions Between the Microbiota and the Immune System
2012 StandoutScience
Activated NKT Cells Inhibit Autoimmune Diabetes through Tolerogenic Recruitment of Dendritic Cells to Pancreatic Lymph Nodes
2005
Production of IL-12 by Human Monocyte-Derived Dendritic Cells Is Optimal When the Stimulus Is Given at the Onset of Maturation, and Is Further Enhanced by IL-4
2001
An Anti-IL-12p40 Antibody Down-Regulates Type 1 Cytokines, Chemokines, and IL-12/IL-23 in Psoriasis
2006
TYPE I INTERFERONS (α/β) IN IMMUNITY AND AUTOIMMUNITY
2004 StandoutNobel
Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model
2012 StandoutNobel
Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag
2009 StandoutNobel
Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood
2016 StandoutNobel
Th2 Lymphoproliferative Disorder of Lat Y136F Mutant Mice Unfolds Independently of TCR-MHC Engagement and Is Insensitive to the Action of Foxp3+ Regulatory T Cells
2008
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
Interleukin-10 and the Interleukin-10 Receptor
2001 Standout
Tumoricidal activity of TLR7/8-activated inflammatory dendritic cells
2007
Dendritic Cells as Adjuvants for Immune-mediated Resistance to Tumors
1997 StandoutNobel
Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease
2014 StandoutScienceNobel
Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function
2020 StandoutNobel
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+regulatory T cells, evoking antitumor immune responses in humans
2013 StandoutNobel
T Cell Regulation as a Side Effect of Homeostasis and Competition
2003
PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors
2010 StandoutNobel
Host-Gut Microbiota Metabolic Interactions
2012 StandoutScience
Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells
2021 StandoutNobel
Serum interleukin-10 levels in patients with advanced gastrointestinal malignancies
1999
Polysialic acid governs T-cell development by regulating progenitor access to the thymus
2009 StandoutNobel
Autoreactivity, dynamic tuning and selectivity
2001
HIV-1-infected monocyte-derived dendritic cells do not undergo maturation but can elicit IL-10 production and T cell regulation
2004 StandoutNobel
Identification of Cellular Pathways of “Type 1,” Th17 T Cells, and TNF- and Inducible Nitric Oxide Synthase-Producing Dendritic Cells in Autoimmune Inflammation through Pharmacogenomic Study of Cyclosporine A in Psoriasis
2008
Cutting Edge: CTLA-4 on Effector T Cells Inhibits In Trans
2012 StandoutNobel
Antibody to Langerin/CD207 localizes large numbers of CD8α + dendritic cells to the marginal zone of mouse spleen
2009 StandoutNobel
Cutting Edge: Cell-Extrinsic Immune Regulation by CTLA-4 Expressed on Conventional T Cells
2012
Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti–CTLA-4 antibody
2018 StandoutNobel
Works of Wolfgang Dummer being referenced
Reliability of reverse transcription-polymerase chain reaction (RT-PCR)-based assays for the detection of circulating tumour cells: a quality-assurance initiative of the EORTC melanoma cooperative group
1998
Interleukin-10 production in malignant melanoma: Preferential detection of IL-10-secreting tumor cells in metastatic lesions
1996
A Novel Targeted T-Cell Modulator, Efalizumab, for Plaque Psoriasis
2003
T-Cell Modulation for the Treatment of Chronic Plaque Psoriasis with Efalizumab (Raptiva™): Mechanisms of Action
2004
Elevated serum levels of interleukin-10 in patients with metastatic malignant melanoma
1995
Subcutaneously Administered Efalizumab (Anti-CD11a) Improves Signs and Symptoms of Moderate to Severe Plaque Psoriasis
2003
T cell homeostatic proliferation elicits effective antitumor autoimmunity
2002
Efalizumab (anti-CD11a)-induced increase in peripheral blood leukocytes in psoriasis patients is preferentially mediated by altered trafficking of memory CD8+ T cells into lesional skin
2004
T cell homeostasis and systemic autoimmunity
2001
Efalizumab for Patients With Moderate to Severe Plaque Psoriasis
2003
Differential expression of transforming growth factor beta 1 and interleukin 10 in progressing and regressing areas of primary melanoma.
1999
T cell homeostatic proliferation elicits effective antitumor autoimmunity
2002
Autologous Regulation of Naive T Cell Homeostasis Within the T Cell Compartment
2001
[Videomicroscopy in differential diagnosis of skin tumors and secondary prevention of malignant melanoma].
1993
T cell homeostatic proliferation elicits effective antitumor autoimmunity
2002
Role of Cyclin Kinase Inhibitor p21 in Systemic Autoimmunity
2001
T cell homeostasis and systemic autoimmunity
2001
Increase in TNF-α and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)
2005 StandoutNobel
The Role of αβ+ T Cells and Homeostatic T Cell Proliferation in Y-Chromosome-Associated Murine Lupus
2001
Lack of Intrinsic CTLA-4 Expression Has Minimal Effect on Regulation of Antiviral T-Cell Immunity
2005
Cutting Edge: Recent Immune Status Determines the Source of Antigens That Drive Homeostatic T Cell Expansion
2005