Citation Impact
Citing Papers
Structural Basis of Transcription Initiation
2012 Science
Structural Basis of Transcription Initiation: RNA Polymerase Holoenzyme at 4 Å Resolution
2002 Science
Structural Basis of Transcription: Backtracked RNA Polymerase II at 3.4 Angstrom Resolution
2009 StandoutScienceNobel
Formation of the First Peptide Bond: The Structure of EF-P Bound to the 70 S Ribosome
2009 StandoutScienceNobel
Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants
2019 StandoutScienceNobel
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
2018 StandoutScienceNobel
Structure of the signal recognition particle interacting with the elongation-arrested ribosome
2004 StandoutNatureNobel
Importing Mitochondrial Proteins: Machineries and Mechanisms
2009
Structural Basis of Transcription: Role of the Trigger Loop in Substrate Specificity and Catalysis
2006 StandoutNobel
Functional Interplay between the Jaw Domain of Bacterial RNA Polymerase and Allele-specific Residues in the Product RNA-binding Pocket
2005
Caenorhabditis elegans pathways that surveil and defend mitochondria
2014 StandoutNatureNobel
Getting Newly Synthesized Proteins into Shape
2000
Crystal structure of a bacterial RNA polymerase holoenzyme at 2.6 Å resolution
2002 Nature
The role of the TATA-binding protein in the assembly and function of the multisubunit yeast RNA polymerase III transcription factor, TFIIIB
1992
The ubiquitin-proteasome proteolytic pathway
1994 StandoutNobel
Signaling the mitochondrial unfolded protein response
2012
Inactivation of Conserved C. elegans Genes Engages Pathogen- and Xenobiotic-Associated Defenses
2012 StandoutNobel
Polypeptide Flux through Bacterial Hsp70
1999
Structure of a new nucleic-acid-binding motif in eukaryotic transcriptional elongation factor TFIIS
1993 Nature
The rde-1 Gene, RNA Interference, and Transposon Silencing in C. elegans
1999 StandoutNobel
In vivo degradation of a transcriptional regulator: The yeast α2 repressor
1990
Mechanism of Polypeptide Translocation into the Endoplasmic Reticulum
1996 StandoutNobel
The Protein Import Machinery of Mitochondria
2004
Mechanisms of asymmetric cell division: Two Bs or not two Bs, that is the question
1992 StandoutNobel
Abortive Cycling and the Release of Polymerase for Elongation at the σ54-dependent glnAp2 Promoter
1995
The N-end rule
1992
In vivo newly translated polypeptides are sequestered in a protected folding environment
1999
Assembly of yeast Sec proteins involved in translocation into the endoplasmic reticulum into a membrane-bound multisubunit complex
1991 StandoutNatureNobel
Structure of the Bacterial RNA Polymerase Promoter Specificity σ Subunit
2002
The degradation signal in a short-lived protein
1989
Compartmentation of protein folding invivo: sequestration of non-native polypeptide by the chaperonin-GimC system
1999
Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis
2019 StandoutNobel
MtGimC, a novel archaeal chaperone related to the eukaryotic chaperonin cofactor GimC/prefoldin
1999
General Transcription Factors for RNA Polymerase II1
1997
Tandem affinity purification revealed the hypusine‐dependent binding of eukaryotic initiation factor 5A to the translating 80S ribosomal complex
2005
Evolutionary conservation and in vitro reconstitution of microsporidian iron–sulfur cluster biosynthesis
2017
Effects of activation-defective TBP mutations on transcription initiation in yeast
1994 StandoutNatureNobel
Mechanism of folding chamber closure in a group II chaperonin
2010 StandoutNatureNobel
Bacterial RNA polymerases: the wholo story
2003
Binding of Secretory Precursor Polypeptides to a Translocon Subcomplex Is Regulated by BiP
1997 StandoutNobel
Two-Dimensional Crystallography of TFIIB– and IIE–RNA Polymerase II Complexes: Implications for Start Site Selection and Initiation Complex Formation
1996 StandoutNobel
Potential role of proteolysis in the control of UvrABC incision
1988
Protein folding and molecular chaperones in Archaea
2001
Signal recognition particle-depencent protein targeting, universal to all kingdoms of life
2002
The Ubiquitin-related BAG-1 Provides a Link between the Molecular Chaperones Hsc70/Hsp70 and the Proteasome
2000
Folding in vivo of bacterial cytoplasmic proteins: Role of GroEL
1993
The interface of sigma with core RNA polymerase is extensive, conserved, and functionally specialized
1999
Lysine 188 of the catabolite gene activator protein (CAP) plays no role in specificity at base pair 7 of the DNA half site
1990
The cellular response to unfolded proteins: intercompartmental signaling
1994
Degradation of nuclear oncoproteins by the ubiquitin system in vitro.
1991 StandoutNobel
Chemical Topology: Complex Molecular Knots, Links, and Entanglements
2011 StandoutNobel
The mouse and human genes encoding the recognition component of the N-end rule pathway
1998 StandoutNobel
The intracellular signal for induction of resistance to alkylating agents in E. coli
1986 StandoutNobel
Architecture of an RNA Polymerase II Transcription Pre-Initiation Complex
2013 StandoutScienceNobel
The Structure of a Transcribing T7 RNA Polymerase in Transition from Initiation to Elongation
2008 StandoutScienceNobel
Active site and complete sequence of the suicidal methyltransferase that counters alkylation mutagenesis.
1985 StandoutNobel
Checkpoints: Controls That Ensure the Order of Cell Cycle Events
1989 StandoutScienceNobel
Folding in vivo of a newly translated yeast cytosolic enzyme is mediated by the SSA class of cytosolic yeast Hsp70 proteins
1998
General requirement for RNA polymerase II holoenzymes in vivo.
1995
Nanoscale distribution of mitochondrial import receptor Tom20 is adjusted to cellular conditions and exhibits an inner-cellular gradient
2011 StandoutNobel
A novel bacterial transcription cycle involving sigma 54.
1995
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
1997 Standout
Potential RNA polymerase II-induced interactions of transcription factor TFIIB.
1993
Prefoldin–Nascent Chain Complexes in the Folding of Cytoskeletal Proteins
1999
Structural Features of the GroEL-GroES Nano-Cage Required for Rapid Folding of Encapsulated Protein
2006
Structural Basis of Transcription: Separation of RNA from DNA by RNA Polymerase II
2004 StandoutScienceNobel
Mutagenesis and inducible responses to deoxyribonucleic acid damage in Escherichia coli
1984
The Interaction of the Chaperonin Tailless Complex Polypeptide 1 (Tcp1) Ring Complex (Tric) with Ribosome-Bound Nascent Chains Examined Using Photo-Cross-Linking
2000
Structural Basis of Transcription: An RNA Polymerase II Elongation Complex at 3.3 Å Resolution
2001 StandoutScienceNobel
Mutations in a Conserved Region of RNA Polymerase II Influence the Accuracy of mRNA Start Site Selection
1991
Interactions of Escherichia coli σ 70 within the transcription elongation complex
1999
Establishment of Cell Type by Compartmentalized Activation of a Transcription Factor
1991 Science
Regulated degradation of the transcription factor Gcn4.
1994
Identification of a contact between arginine-180 of the catabolite gene activator protein (CAP) and base pair 5 of the DNA site in the CAP-DNA complex.
1990
Substrate spectrum of human excinuclease: repair of abasic sites, methylated bases, mismatches, and bulky adducts.
1994 StandoutNobel
Promoter Recognition As Measured by Binding of Polymerase to Nontemplate Strand Oligonucleotide
1997 Science
BiP and Sec63p are required for both co- and posttranslational protein translocation into the yeast endoplasmic reticulum.
1995 StandoutNobel
DNA Components for Molecular Architecture
1997
Molecular Chaperones in the Cytosol: from Nascent Chain to Folded Protein
2002 StandoutScience
Protein synthesis elongation factor EF-1 alpha is essential for ubiquitin-dependent degradation of certain N alpha-acetylated proteins and may be substituted for by the bacterial elongation factor EF-Tu.
1994 StandoutNobel
Involvement of the Molecular Chaperone Ydj1 in the Ubiquitin-Dependent Degradation of Short-Lived and Abnormal Proteins in Saccharomyces cerevisiae
1996
Universality and Structure of the N-end Rule
1989
Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway.
1995 StandoutNobel
Translocation of Proteins into Mitochondria
2007
Crystal Structure of a CAP-DNA Complex: the DNA Is Bent by 90°
1991 StandoutScienceNobel
Structural Perspective on Mutations Affecting the Function of Multisubunit RNA Polymerases
2006
RAC, a stable ribosome-associated complex in yeast formed by the DnaK-DnaJ homologs Ssz1p and zuotin
2001
Heat Shock Protein-mediated Disassembly of Nucleoprotein Structures Is Required for the Initiation of Bacteriophage λ DNA Replication
1989
Complete, 12-subunit RNA polymerase II at 4.1-Å resolution: Implications for the initiation of transcription
2003 StandoutNobel
Elution of proteins from sodium dodecyl sulfate-polyacrylamide gels, removal of sodium dodecyl sulfate, and renaturation of enzymatic activity: Results with sigma subunit of Escherichia coli RNA polymerase, wheat germ DNA topoisomerase, and other enzymes
1980
Architecture of RNA Polymerase II and Implications for the Transcription Mechanism
2000 StandoutScienceNobel
Folding of Newly Translated Proteins In Vivo: The Role of Molecular Chaperones
2001
Mediator protein mutations that selectively abolish activated transcription
1999 StandoutNobel
Cooperative Interactions Between the Caenorhabditis elegans Homeoproteins UNC-86 and MEC-3
1993 StandoutScienceNobel
The structure of a CAP–DNA complex having two cAMP molecules bound to each monomer
1997 StandoutNobel
Basal and human papillomavirus E6 oncoprotein-induced degradation of Myc proteins by the ubiquitin pathway
1998 StandoutNobel
The General Transcription Factor RAP30 Binds to RNA Polymerase II and Prevents It from Binding Nonspecifically to DNA
1992
Structural Basis for the Transition from Initiation to Elongation Transcription in T7 RNA Polymerase
2002 StandoutScienceNobel
The recognition component of the N-end rule pathway.
1990
The htpR gene product of E. coli is a sigma factor for heat-shock promoters
1984
Structural Basis of Transcription: An RNA Polymerase II-TFIIB Cocrystal at 4.5 Angstroms
2004 StandoutScienceNobel
Mutations in a conserved region of RNA polymerase II influence the accuracy of mRNA start site selection.
1991
Independent Pathways for Secretion of Cholesterol and Apolipoprotein E by Macrophages
1983 StandoutScienceNobel
A yeast gene important for protein assembly into the endoplasmic reticulum and the nucleus has homology to DnaJ, an Escherichia coli heat shock protein.
1989
Structural homology between the Rap30 DNA-binding domain and linker histone H5: Implications for preinitiation complex assembly
1998
The mitochondrial UPR – protecting organelle protein homeostasis
2010
Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom Resolution
2001 StandoutScienceNobel
THE UBIQUITIN SYSTEM
1998 StandoutNobel
The N-End Rule in Bacteria
1991 Science
Termination-altering amino acid substitutions in the beta' subunit of Escherichia coli RNA polymerase identify regions involved in RNA chain elongation.
1994
Elicitation of structure-specific antibodies by epitope scaffolds
2010 StandoutNobel
Protein Translocation Across Biological Membranes
2005 StandoutScienceNobel
Structure and Function of DNA Photolyase and Cryptochrome Blue-Light Photoreceptors
2003 StandoutNobel
Works of William Walter being referenced
Human Mpp11 J Protein: Ribosome-Tethered Molecular Chaperones Are Ubiquitous
2005 Science
The in vivo function of the ribosome-associated Hsp70, Ssz1, does not require its putative peptide-binding domain
2002
The molecular chaperone Ssb from Saccharomyces cerevisiae is a component of the ribosome–nascent chain complex
1998
Ssq1, a Mitochondrial Hsp70 Involved in Iron-Sulfur (Fe/S) Center Biogenesis
2003
Regulated interactions of mtHsp70 with Tim44 at the translocon in the mitochondrial inner membrane
2004
Genetic Evidence for the Interaction between Cluster I and Cluster III Rifampicin Resistant Mutations
1993
Altered promoter recognition by mutant forms of the σ70 subunit of Escherichia coli RNA polymerase
1989
The Hsp70 Ssz1 modulates the function of the ribosome-associated J-protein Zuo1
2005
Characterization of the termination phenotypes of rifampicin-resistant mutants
1988
Polypeptides containing highly conserved regions of transcription initiation factor σ70 exhibit specificity of binding to promoter DNA
1992
Involvement of the DnaK-DnaJ-GrpE chaperone team in protein secretion in Escherichia coli
1996
Amino-terminal amino acids modulate sigma-factor DNA-binding activity.
1993
Altered chemical properties in three mutants of E. coli RNA polymerase sigma subunit
1979
Functional Interaction of Cytosolic hsp70 and a DnaJ-Related Protein, Ydj1p, in Protein Translocation In Vivo
1996
Effects of the mutant sigma allele rpoD800 on the synthesis of specific macromolecular components of the Escherichia coli K12 cell
1984
Accumulation of secretory protein precursors in Escherichia coli induces the heat shock response
1993
J protein cochaperone of the mitochondrial inner membrane required for protein import into the mitochondrial matrix
2003
The heat shock response of E. coli is regulated by changes in the concentration of σ32
1987 Nature
Escherichia coli heat shock gene mutants are defective in proteolysis.
1988
Regulated Cycling of Mitochondrial Hsp70 at the Protein Import Channel
2003 Science
Sigma 32 synthesis can regulate the synthesis of heat shock proteins in Escherichia coli.
1987
DnaK, DnaJ, and GrpE heat shock proteins negatively regulate heat shock gene expression by controlling the synthesis and stability of sigma 32.
1990
Role of Pam16's degenerate J domain in protein import across the mitochondrial inner membrane
2005
Mutations in the Lon gene of E. coli K12 phenotypically suppress a mutation in the sigma subunit of RNA polymerase
1983