Standout Papers
Citation Impact
Citing Papers
Profound Coordinated Alterations of Intratumoral NK Cell Phenotype and Function in Lung Carcinoma
2011
ERK1/2 and p38α/β Signaling in Tumor Cell Quiescence: Opportunities to Control Dormant Residual Disease
2011
Differential Antigen Processing by Dendritic Cell Subsets in Vivo
2007 StandoutScienceNobel
Coordination of Intratumoral Immune Reaction and Human Colorectal Cancer Recurrence
2009
Checkpoint Blockade Immunotherapy Relies on T-bet but Not Eomes to Induce Effector Function in Tumor-Infiltrating CD8+ T Cells
2014
Conditional Regulatory T-Cell Depletion Releases Adaptive Immunity Preventing Carcinogenesis and Suppressing Established Tumor Growth
2010
Localization and Density of Immune Cells in the Invasive Margin of Human Colorectal Cancer Liver Metastases Are Prognostic for Response to Chemotherapy
2011
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
2013 StandoutScienceNobel
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Interactions between lymphocytes and myeloid cells regulate pro- versus anti-tumor immunity
2010
Dendritic cells as therapeutic vaccines against cancer
2005
IL-22+CD4+ T Cells Promote Colorectal Cancer Stemness via STAT3 Transcription Factor Activation and Induction of the Methyltransferase DOT1L
2014
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
SEC14L2 enables pan-genotype HCV replication in cell culture
2015 StandoutNatureNobel
Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and Treg cells
2011 Nature
Transmission of donor melanoma by organ transplantation
2010
Tumor cells disseminate early, but immunosurveillance limits metastatic outgrowth, in a mouse model of melanoma
2010
Cancer Immunosurveillance and Immunoediting: The Roles of Immunity in Suppressing Tumor Development and Shaping Tumor Immunogenicity
2006
Inflammation and Cancer: Triggers, Mechanisms, and Consequences
2019 Standout
Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration
2018
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Regulation of the IL-23 and IL-12 Balance by Stat3 Signaling in the Tumor Microenvironment
2009
Genetic analysis of resistance to viral infection
2007 StandoutNobel
Mammalian phosphoinositide kinases and phosphatases
2009 StandoutNobel
Microglial brain region−dependent diversity and selective regional sensitivities to aging
2016
Environment Drives Selection and Function of Enhancers Controlling Tissue-Specific Macrophage Identities
2014
C-type lectin receptors on dendritic cells and langerhans cells
2002
Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future
2017 Standout
Neuro-immune Interactions Drive Tissue Programming in Intestinal Macrophages
2016
Mechanisms of disseminated cancer cell dormancy: an awakening field
2014
Dendritic Cell Function in Vivo during the Steady State: A Role in Peripheral Tolerance
2003 StandoutNobel
The Continuum of Cancer Immunosurveillance: Prognostic, Predictive, and Mechanistic Signatures
2013
Hallmarks of cancer: Interactions with the tumor stroma
2010
TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model
2015 Standout
Expression of tumour-specific antigens underlies cancer immunoediting
2012 Nature
Neutrophils in the activation and regulation of innate and adaptive immunity
2011 Standout
Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity
2017 StandoutNobel
Microbial Stimulation Fully Differentiates Monocytes to DC-SIGN/CD209+ Dendritic Cells for Immune T Cell Areas
2010 StandoutNobel
Immune Signaling by RIG-I-like Receptors
2011
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
PI3Kγ inhibition: towards an 'aspirin of the 21st century'?
2006
Dendritic cells: a journey from laboratory to clinic
2003
Targeting macrophages: therapeutic approaches in cancer
2018
CD4+ T Cells Regulate Pulmonary Metastasis of Mammary Carcinomas by Enhancing Protumor Properties of Macrophages
2009
Immunity, Inflammation, and Cancer
2010 Standout
Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways
2017 StandoutNobel
Dendritic-cell trafficking to lymph nodes through lymphatic vessels
2005
Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape
2012
RORγt+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota
2011
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Human occludin is a hepatitis C virus entry factor required for infection of mouse cells
2009 StandoutNatureNobel
Melanomas resist T-cell therapy through inflammation-induced reversible dedifferentiation
2012 Nature
Emerging Biological Principles of Metastasis
2017 Standout
Fibroblasts as architects of cancer pathogenesis
2012
STATs in cancer inflammation and immunity: a leading role for STAT3
2009 Standout
The Immunoreceptor TIGIT Regulates Antitumor and Antiviral CD8 + T Cell Effector Function
2014
T Cell Surveillance of Oncogene-Induced Prostate Cancer Is Impeded by T Cell-Derived TGF-β1 Cytokine
2011 StandoutNobel
The immune contexture in human tumours: impact on clinical outcome
2012 Standout
Biomolecular Network Reconstruction Identifies T-Cell Homing Factors Associated With Survival in Colorectal Cancer
2009
Tumor immunosurveillance in human cancers
2011
TNFR1 Signaling and IFN-γ Signaling Determine whether T Cells Induce Tumor Dormancy or Promote Multistage Carcinogenesis
2008
Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts
2006
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
Tumor microenvironment is multifaceted
2011
Cancer Immunotherapy by Dendritic Cells
2008
Diverse Requirements for Microglial Survival, Specification, and Function Revealed by Defined-Medium Cultures
2017
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Genetics and pathogenesis of inflammatory bowel disease
2011 StandoutNature
In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses
2009
Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer
2013 Standout
A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses
2009
Transmembrane proteins of tight junctions
2007
Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting
2012 StandoutNatureNobel
Tumour necrosis factor and cancer
2009
Cancer Immunology
2008
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Interferon-producing cells: on the front line in immune responses against pathogens
2002
Dendritic cell immunotherapy: mapping the way
2004
Natural immunity to cancer in humans
2010
Mutant MHC class II epitopes drive therapeutic immune responses to cancer
2015 Nature
Cancer-related inflammation
2008 StandoutNature
Hypoxia Promotes Tumor Growth in Linking Angiogenesis to Immune Escape
2012
Microenvironmental regulation of tumor progression and metastasis
2013 Standout
Origin of dendritic cells in peripheral lymphoid organs of mice
2007
Plasmacytoid Dendritic Cells: A New Cutaneous Dendritic Cell Subset with Distinct Role in Inflammatory Skin Diseases
2002
Dendritic cell–endothelial cell cross-talk in angiogenesis
2007
Tumors as Organs: Complex Tissues that Interface with the Entire Organism
2010
Type I interferons in anticancer immunity
2015
Extracellular matrix: A gatekeeper in the transition from dormancy to metastatic growth
2010
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells
2010 StandoutNobel
Isolation and Culture of Microglia
2018
Cancer immunoediting: antigens, mechanisms, and implications to cancer immunotherapy
2013
The CD8+ Dendritic Cell Subset Selectively Endocytoses Dying Cells in Culture and In Vivo
2002 StandoutNobel
IL-23 suppresses innate immune response independently of IL-17A during carcinogenesis and metastasis
2010
Cancer immunotherapy: co-stimulatory agonists and co-inhibitory antagonists
2009 StandoutNobel
Expression of an anti‐RNA autoantibody in a mouse model of SLE increases neutrophil and monocyte numbers as well as IFN ‐I expression
2013
Natural Innate and Adaptive Immunity to Cancer
2011 Standout
Plasmacytoid predendritic cells initiate psoriasis through interferon-α production
2005
In Situ Cytotoxic and Memory T Cells Predict Outcome in Patients With Early-Stage Colorectal Cancer
2009
Anti–ErbB-2 mAb therapy requires type I and II interferons and synergizes with anti–PD-1 or anti-CD137 mAb therapy
2011
Micrometastatic Disease and Metastatic Outgrowth: Clinical Issues and Experimental Approaches
2009
Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion
2011 StandoutScience
Immunological mechanisms of the antitumor effects of supplemental oxygenation
2015
Therapeutic Targeting of the Tumor Microenvironment
2021
Fundamental Mechanisms of Immune Checkpoint Blockade Therapy
2018 StandoutNobel
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients
2008 StandoutNobel
Immune-mediated dormancy: an equilibrium with cancer
2008
Differential Induction of Type I Interferon Responses in Myeloid Dendritic Cells by Mosquito and Mammalian-Cell-Derived Alphaviruses
2006
Foxp3+natural regulatory T cells preferentially form aggregates on dendritic cellsin vitroand actively inhibit their maturation
2008 StandoutNobel
Increase in TNF-α and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)
2005 StandoutNobel
Type I interferon is selectively required by dendritic cells for immune rejection of tumors
2011
IPC: Professional Type 1 Interferon-Producing Cells and Plasmacytoid Dendritic Cell Precursors
2004
Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments
2009
Immunosuppressive Strategies that are Mediated by Tumor Cells
2006
Tumoricidal activity of TLR7/8-activated inflammatory dendritic cells
2007
The future of immune checkpoint therapy
2015 StandoutScienceNobel
Efficient Targeting of Protein Antigen to the Dendritic Cell Receptor DEC-205 in the Steady State Leads to Antigen Presentation on Major Histocompatibility Complex Class I Products and Peripheral CD8+ T Cell Tolerance
2002 StandoutNobel
The systemic response to surgery triggers the outgrowth of distant immune-controlled tumors in mouse models of dormancy
2018
Transient regulatory T cell ablation deters oncogene-driven breast cancer and enhances radiotherapy
2013
TIGIT and PD-1 impair tumor antigen–specific CD8+ T cells in melanoma patients
2015
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+regulatory T cells, evoking antitumor immune responses in humans
2013 StandoutNobel
Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens
2000
Toll-like receptor 3 signaling converts tumor-supporting myeloid cells to tumoricidal effectors
2012
Immunotherapy: Bewitched, Bothered, and Bewildered No More
2004 StandoutScienceNobel
Neoantigens in cancer immunotherapy
2015 StandoutScience
Tolerogenic Dendritic Cells
2003 StandoutNobel
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
Immune Therapy for Cancer
2008
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Activation of fibroblasts in cancer stroma
2010
Dual Roles for Immunity in Gastrointestinal Cancers
2010
Mouse TIGIT inhibits NK ‐cell cytotoxicity upon interaction with PVR
2013
Works of William Vermi being referenced
Cancer immunoediting by the innate immune system in the absence of adaptive immunity
2012
Adaptive immunity maintains occult cancer in an equilibrium state
2007 Nature
Role of dendritic cell-derived CXCL13 in the pathogenesis of Bartonella henselae B-rich granuloma
2005
Macrophage colony-stimulating factor induces the proliferation and survival of macrophages via a pathway involving DAP12 and β-catenin
2009
A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity
2008 StandoutNature
Recruitment of immature plasmacytoid dendritic cells (plasmacytoid monocytes) and myeloid dendritic cells in primary cutaneous melanomas
2003
RNA sensor–induced type I IFN prevents diabetes caused by a β cell–tropic virus in mice
2011
Intraepithelial Type 1 Innate Lymphoid Cells Are a Unique Subset of IL-12- and IL-15-Responsive IFN-γ-Producing Cells
2013
IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia
2012
Defective dendritic cell migration and activation of adaptive immunity in PI3Kγ‐deficient mice
2004
A novel molecular interaction for the adhesion of follicular CD4 T cells to follicular DC
2009
Dysregulated STAT1-SOCS1 control of JAK2 promotes mammary luminal progenitor cell survival and drives ERα+ tumorigenesis
2013
Loss of DNAM‐1 contributes to CD8+ T‐cell exhaustion in chronic HIV‐1 infection
2010
Expression of Inducible Nitric Oxide Synthase in Human Granulomas and Histiocytic Reactions
1999
Plasmacytoid dendritic cells prime IFN‐γ‐secreting melanoma‐specific CD8 lymphocytes and are found in primary melanoma lesions
2003
On the potential involvement of CD11d in co-stimulating the production of interferon- by natural killer cells upon interaction with neutrophils via intercellular adhesion molecule-3
2011
Recruitment of dendritic cells in oral lichen planus
2005
Increased DC trafficking to lymph nodes and contact hypersensitivity in junctional adhesion molecule-A–deficient mice
2004
Role of ChemR23 in directing the migration of myeloid and plasmacytoid dendritic cells to lymphoid organs and inflamed skin
2005
A cell-surface molecule selectively expressed on murine natural interferon–producing cells that blocks secretion of interferon-alpha
2003
Essential role of PI3Kδ and PI3Kγ in thymocyte survival
2005
Human neutrophils interact with both 6-sulfo LacNAc+ DC and NK cells to amplify NK-derived IFNγ: role of CD18, ICAM-1, and ICAM-3
2010
Distinct and complementary functions of MDA5 and TLR3 in poly(I:C)-mediated activation of mouse NK cells
2009
Melanoma-associated fibroblasts modulate NK cell phenotype and antitumor cytotoxicity
2009
BDCA-2, a Novel Plasmacytoid Dendritic Cell–specific Type II C-type Lectin, Mediates Antigen Capture and Is a Potent Inhibitor of Interferon α/β Induction
2001