Citation Impact
Citing Papers
IDO Is a Nodal Pathogenic Driver of Lung Cancer and Metastasis Development
2012
Inhibition of Indoleamine 2,3-Dioxygenase in Dendritic Cells by Stereoisomers of 1-Methyl-Tryptophan Correlates with Antitumor Responses
2007
Immunotherapeutic Suppression of Indoleamine 2,3-Dioxygenase and Tumor Growth with Ethyl Pyruvate
2010
Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion
2019 Science
Immune-modulating enzyme indoleamine 2,3-dioxygenase is effectively inhibited by targeting its apo-form
2018
The Immunoregulatory Enzyme IDO Paradoxically Drives B Cell-Mediated Autoimmunity
2009
Constitutive Expression of IDO by Dendritic Cells of Mesenteric Lymph Nodes: Functional Involvement of the CTLA-4/B7 and CCL22/CCR4 Interactions
2009 StandoutNobel
An Aryl Hydrocarbon Receptor-Mediated Amplification Loop That Enforces Cell Migration in ER−/PR−/Her2− Human Breast Cancer Cells
2016
A prospective phase II trial exploring the association between tumor microenvironment biomarkers and clinical activity of ipilimumab in advanced melanoma
2011
Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models
2012
Bifunctional phosphine-catalyzed cross-Rauhut–Currier/Michael/aldol condensation triple domino reaction: synthesis of functionalized cyclohexenes
2011
Intramolecular Regulation of Protein Tyrosine Phosphatase SH-PTP1: A New Function for Src Homology 2 Domains
1994
High-Throughput Fluorescence-Based Screening Assays for Tryptophan-Catabolizing Enzymes
2014
Necroptosis and its role in inflammation
2015 StandoutNature
The kynurenine pathway and the brain: Challenges, controversies and promises
2016
Organocatalytic Synthesis of Highly Functionalized Pyridines at Room Temperature
2013
IDO-expressing regulatory dendritic cells in cancer and chronic infection
2007
The biology and management of non-small cell lung cancer
2018 StandoutNature
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
2011 StandoutNature
Substrate‐Controlled, Phosphine‐Catalyzed Domino Reactions of Activated Conjugated Dienes: Highly Diastereoselective Synthesis of Bicyclic Skeletons
2011
Host Indoleamine 2,3-Dioxygenase: Contribution to Systemic Acquired Tumor Tolerance
2012
Targeting the mechanisms of tumoral immune tolerance with small-molecule inhibitors
2006
The X-ray Crystal Structures of Yersinia Tyrosine Phosphatase with Bound Tungstate and Nitrate
1996
Catalytic Asymmetric [4+2] Annulation Initiated by an Aza‐Rauhut–Currier Reaction: Facile Entry to Highly Functionalized Tetrahydropyridines
2012
Interdependent IL-7 and IFN-γ signalling in T-cell controls tumour eradication by combined α-CTLA-4+α-PD-1 therapy
2016 StandoutNobel
Indoleamine 2,3‐dioxygenase in T‐cell tolerance and tumoral immune escape
2008
Hydrolysis of DNA model substrates catalyzed by metal-substituted Wells–Dawson polyoxometalates
2012
Myeloid-derived suppressor cells as regulators of the immune system
2009 Standout
Inhibitors of indoleamine-2,3-dioxygenase for cancer therapy: can we see the wood for the trees?
2009
Enantioselective Synthesis of α‐Alkylidene‐γ‐Butyrolactones: Intramolecular Rauhut–Currier Reaction Promoted by Acid/Base Organocatalysts
2012
Indoleamine 2,3-dioxygenase pathways of pathogenic inflammation and immune escape in cancer
2014
Cascade Reactions in Total Synthesis
2006 Standout
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
2017 Standout
Formation of an N-formylkynurenine-derived fluorophore and its use for measuring indoleamine 2,3-dioxygenase 1 activity
2013
Cancer immunotherapy comes of age
2011 StandoutNature
Phosphoramidites: Privileged Ligands in Asymmetric Catalysis
2010 StandoutNobel
The blockade of immune checkpoints in cancer immunotherapy
2012 Standout
Tryptophan degradation in autoimmune diseases
2007
Protein Tyrosine Phosphatases in the Human Genome
2004 Standout
Development of tumor mutation burden as an immunotherapy biomarker: utility for the oncology clinic
2018 Standout
Indoleamine 2,3-Dioxygenase in Immune Suppression and Cancer
2007
Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond
2019 Standout
Imatinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido
2011 StandoutNobel
Protein tyrosine phosphatases take off
1995
Microenvironmental regulation of tumor progression and metastasis
2013 Standout
Obstructive sleep apnoea and its cardiovascular consequences
2008 Standout
Energetics of nucleophile activation in a protein tyrosine phosphatase
1997
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
2009 Standout
Synthesis of seven-membered oxacycles
1998
Quantitative exploration of the molecular origin of the activation of GTPase
2013 StandoutNobel
Catalytic Asymmetric Additions of Enol Silanes to In Situ Generated Cyclic, AliphaticN‐Acyliminium Ions
2021 StandoutNobel
Biologically active quinoline and quinazoline alkaloids part I
2017
Bond Formations between Two Nucleophiles: Transition Metal Catalyzed Oxidative Cross-Coupling Reactions
2011 Standout
Important Hydrogen Bond Networks in Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitor Design Revealed by Crystal Structures of Imidazoleisoindole Derivatives with IDO1
2015
Role of indoleamine 2,3-dioxygenase in health and disease
2015
Chemistry of Polyvalent Iodine
2008 Standout
Challenges in the Discovery of Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors
2015
Energetics and Dynamics of Enzymatic Reactions
2001 StandoutNobel
Biologically active quinoline and quinazoline alkaloids part II
2018
Highly Enantioselective Synthesis of 3,4-Dihydropyrans through a Phosphine-Catalyzed [4+2] Annulation of Allenones and β,γ-Unsaturated α-Keto Esters
2014
P-Acylphosphonium salts and their vinyloges — application in synthesis
2010
The synthesis of enantiomerically pure, symmetrically substituted cyclopropane phosphonic acids — A constrained analog of the GABA antagonist phaclophen
1997
Amino acid catabolism: a pivotal regulator of innate and adaptive immunity
2012
Mitsunobu and Related Reactions: Advances and Applications
2009
Kynurenine Pathway Enzymes in Dendritic Cells Initiate Tolerogenesis in the Absence of Functional IDO
2006
Homologation of the Fischer Indolization: A Quinoline Synthesis via Homo‐Diaza‐Cope Rearrangement
2020 StandoutNobel
Phosphine Organocatalysis
2018 Standout
Computer Simulation of the Chemical Catalysis of DNA Polymerases: Discriminating between Alternative Nucleotide Insertion Mechanisms for T7 DNA Polymerase
2003 StandoutNobel
Catalytic Asymmetric Hydroalkoxylation of C–C Multiple Bonds
2021 StandoutNobel
Use of Lawesson's Reagent in Organic Syntheses
2007 Standout
Intramolecular Morita–Baylis–Hillman and Rauhut–Currier reactions. A catalytic and atom economic route for carbocycles and heterocycles
2015
Advances in the Chemistry of Tetrahydroquinolines
2011 Standout
Recent Advances in Polyoxometalate-Catalyzed Reactions
2015 Standout
Stereoselective Cyclopropanation Reactions
2003 Standout
Toward Accurate Screening in Computer-Aided Enzyme Design
2009 StandoutNobel
Mechanisms and stereoselectivities of phosphine-catalyzed Rauhut-Currier reaction between N-phenylmaleimide and 2-benzoyl acrylate: A computational investigation
2017
General Access to theVincaandTacamanAlkaloids Using a Rh(II)-Catalyzed Cyclization/Cycloaddition Cascade
2008
Inhibitory Substrate Binding Site of Human Indoleamine 2,3-Dioxygenase
2009
Addressing Open Questions about Phosphate Hydrolysis Pathways by Careful Free Energy Mapping
2012 StandoutNobel
The Chemistry and Biochemistry of Vanadium and the Biological Activities Exerted by Vanadium Compounds
2004 Standout
An Expeditious Route to Novel 1,4,2-Benzodiazaphosphepin-5-one 2-Oxide Analogues
1999
Oxidative Friedel−Crafts Reaction and its Application to the Total Syntheses of Amaryllidaceae Alkaloids
2009
Stereoselective Construction of Quaternary Stereocenters
2005
Enzymatic Mechanisms of Phosphate and Sulfate Transfer
2006
Metabolic reprogramming and cancer progression
2020 StandoutScience
Cyclizations of N-Acyliminium Ions
2004 Standout
Progress in Ab Initio QM/MM Free-Energy Simulations of Electrostatic Energies in Proteins: Accelerated QM/MM Studies of pKa, Redox Reactions and Solvation Free Energies
2008 StandoutNobel
Enantioselective Construction of All‐Carbon Quaternary Stereogenic Centers by Using Phosphine Catalysis
2017
Regioselective Functionalization of the Imidazole Ring via Transition Metal‐Catalyzed CN and CC Bond Forming Reactions
2010
Electrostatic Basis for Enzyme Catalysis
2006 StandoutNobel
Advances in Synthetic Applications of Hypervalent Iodine Compounds
2016 Standout
Ab Initio Evaluation of the Free Energy Surfaces for the General Base/Acid Catalyzed Thiolysis of Formamide and the Hydrolysis of Methyl Thiolformate: A Reference Solution Reaction for Studies of Cysteine Proteases
2001 StandoutNobel
A patent review of IDO1 inhibitors for cancer
2018
Quantifying the Mechanism of Phosphate Monoester Hydrolysis in Aqueous Solution by Evaluating the Relevant Ab Initio QM/MM Free-Energy Surfaces
2013 StandoutNobel
Phosphine-catalyzed intramolecular Rauhut–Currier reaction: enantioselective synthesis of hydro-2H-indole derivatives
2017
T cell exclusion, immune privilege, and the tumor microenvironment
2015 StandoutScience
Tryptophan 2,3-Dioxygenase (TDO) Inhibitors. 3-(2-(Pyridyl)ethenyl)indoles as Potential Anticancer Immunomodulators
2011
Immunological and Nonimmunological Effects of Indoleamine 2,3-Dioxygenase on Breast Tumor Growth and Spontaneous Metastasis Formation
2012
Enzyme millisecond conformational dynamics do not catalyze the chemical step
2009 StandoutNobel
Synthesis of a New Class of Highly Functionalized Phosphorus Ylides Containing Heterocyclic Compounds
2012
Facile synthesis of α-methylidene-γ-butyrolactones: intramolecular Rauhut–Currier reaction promoted by chiral acid–base organocatalysts
2012
On the Interpretation of the Observed Linear Free Energy Relationship in Phosphate Hydrolysis: A Thorough Computational Study of Phosphate Diester Hydrolysis in Solution
2008 StandoutNobel
Indoleamine 2,3-dioxygenase is a critical resistance mechanism in antitumor T cell immunotherapy targeting CTLA-4
2013 StandoutNobel
Free Radicals in the Physiological Control of Cell Function
2002 Standout
How Does GAP Catalyze the GTPase Reaction of Ras?: A Computer Simulation Study
2000 StandoutNobel
Metal-Free Multicomponent Syntheses of Pyridines
2014 Standout
Toward the identification of a tolerogenic signature in IDO-competent dendritic cells
2005
Mechanism of substrate dephosphorylation in lowMr protein tyrosine phosphatase
1999
Ferrocene Derived Bifunctional Phosphine‐Catalyzed Asymmetric Oxa‐[4+2] Cycloaddition of α‐Substituted Allenones with Enones
2017
Works of William P. Malachowski being referenced
A key in vivo antitumor mechanism of action of natural product-based brassinins is inhibition of indoleamine 2,3-dioxygenase
2007
O-alkylhydroxylamines as rationally-designed mechanism-based inhibitors of indoleamine 2,3-dioxygenase-1
2015
Indoleamine 2,3-Dioxygenase Is the Anticancer Target for a Novel Series of Potent Naphthoquinone-Based Inhibitors
2008
Sequential Birch reduction–allylation and Cope rearrangement of o-anisic acid derivatives
2004
Nature of the rate-determining steps of the reaction catalyzed by the Yersinia protein-tyrosine phosphatase.
1994
Structure−Activity Study of Brassinin Derivatives as Indoleamine 2,3-Dioxygenase Inhibitors
2005
The Chemistry of Phosphapeptides: Formation of Functionalized Phosphonochloridates under Mild Conditions and Their Reaction with Alcohols and Amines
1994
A new cancer immunosuppression target: Indoleamine 2,3-dioxygenase (IDO). A review of the IDO mechanism, inhibition and therapeutic applications
2005
Asymmetric Total Synthesis of (+)-Apovincamine and a Formal Synthesis of (+)-Vincamine. Demonstration of a Practical “Asymmetric Linkage” between Aromatic Carboxylic Acids and Chiral Acyclic Substrates
1997
The Synthesis of Azapeptidomimetic β-Lactam Molecules as Potential Protease Inhibitors
2002
Discovery of IDO1 Inhibitors: From Bench to Bedside
2017
The Enantioselective Birch−Cope Sequence for the Synthesis of Carbocyclic Quaternary Stereocenters. Application to the Synthesis of (+)-Mesembrine
2006
Indoleamine 2,3-Dioxygenase and Its Therapeutic Inhibition in Cancer
2017
Enantioselective synthesis of bicarbocyclic structures with an all-carbon quaternary stereocenter through sequential cross metathesis and intramolecular Rauhut–Currier reaction
2010
Indoleamine 2,3-dioxygenase in cancer: targeting pathological immune tolerance with small-molecule inhibitors
2005
Enantioselective synthesis of decalin structures with all-carbon quaternary centers via one-pot sequential Cope/Rauhut–Currier reaction
2014
The Chemistry of Phosphapeptides: Investigations on the Synthesis of Phosphonamidate, Phosphonate, and Phosphinate Analogs of Glutamyl-.gamma.-glutamate
1994
The Tumor-Selective Cytotoxic Agent β-Lapachone is a Potent Inhibitor of IDO1
2013
Structure Based Development of Phenylimidazole-Derived Inhibitors of Indoleamine 2,3-Dioxygenase
2008
A general strategy for the synthesis of azapeptidomimetic lactams
2005