Standout Papers
- Countercurrent Distribution of Two Distinct SNARE Complexes Mediating Transport within the Golgi Stack (2004)
- Alternative Zippering as an On-Off Switch for SNARE-Mediated Fusion (2009)
- Distinct Domains of Complexins Bind SNARE Complexes and Clamp Fusion in Vitro (2008)
- Localization and activity of the SNARE Ykt6 determined by its regulatory domain and palmitoylation (2004)
- Energetics and dynamics of SNAREpin folding across lipid bilayers (2007)
Citation Impact
Citing Papers
Evidence that Electrostatic Interactions between Vesicle-associated Membrane Protein 2 and Acidic Phospholipids May Modulate the Fusion of Transport Vesicles with the Plasma Membrane
2009
Differential use of endoplasmic reticulum membrane for phagocytosis in J774 macrophages
2005 StandoutNobel
Ultrahigh-resolution imaging reveals formation of neuronal SNARE/Munc18 complexes in situ
2013 StandoutNobel
In vitro system capable of differentiating fast Ca 2+ -triggered content mixing from lipid exchange for mechanistic studies of neurotransmitter release
2011 Nobel
Complexin Controls the Force Transfer from SNARE Complexes to Membranes in Fusion
2009 StandoutScienceNobel
Single Reconstituted Neuronal SNARE Complexes Zipper in Three Distinct Stages
2012 StandoutScienceNobel
SNARE Proteins: One to Fuse and Three to Keep the Nascent Fusion Pore Open
2012 StandoutScienceNobel
Conformational Switch of Syntaxin-1 Controls Synaptic Vesicle Fusion
2008 StandoutScienceNobel
α-Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro
2010 StandoutScienceNobel
A fast, single-vesicle fusion assay mimics physiological SNARE requirements
2010 StandoutNobel
Multiple intermediates in SNARE-induced membrane fusion
2006
Two synaptobrevin molecules are sufficient for vesicle fusion in central nervous system synapses
2011
Syntaxin N-terminal peptide motif is an initiation factor for the assembly of the SNARE–Sec1/Munc18 membrane fusion complex
2010
Munc18-1 binds directly to the neuronal SNARE complex
2007 StandoutNobel
Dynamic structure of lipid-bound synaptobrevin suggests a nucleation-propagation mechanism for trans-SNARE complex formation
2009
Fast Vesicle Fusion in Living Cells Requires at Least Three SNARE Complexes
2010 ScienceNobel
Recent developments in esophageal adenocarcinoma
2013
Chemical Regulation of Glycosylation Processes
2018
RIM Proteins Tether Ca2+ Channels to Presynaptic Active Zones via a Direct PDZ-Domain Interaction
2011 StandoutNobel
Synaptotagmin arrests the SNARE complex before triggering fast, efficient membrane fusion in response to Ca2+
2008
A conformational switch in complexin is required for synaptotagmin to trigger synaptic fusion
2011 StandoutNobel
Cell biology of Ca2+-triggered exocytosis
2010 StandoutNobel
Intracellular Bacteria Encode Inhibitory SNARE-Like Proteins
2009 StandoutNobel
Putting the clamps on membrane fusion: How complexin sets the stage for calcium‐mediated exocytosis
2007
Distinct domains of complexin I differentially regulate neurotransmitter release
2007
A complexin fusion clamp regulates spontaneous neurotransmitter release and synaptic growth
2007
Differential regulation of evoked and spontaneous neurotransmitter release by C-terminal modifications of complexin
2012
SNARE Requirements En Route to Exocytosis: from Many to Few
2012
SNARE Force Synchronizes Synaptic Vesicle Fusion and Controls the Kinetics of Quantal Synaptic Transmission
2010
Calcium Control of Neurotransmitter Release
2011
C-Terminal Complexin Sequence Is Selectively Required for Clamping and Priming But Not for Ca2+Triggering of Synaptic Exocytosis
2012 StandoutNobel
Exosomes in the gut
2014
Neurotransmitter Release: The Last Millisecond in the Life of a Synaptic Vesicle
2013 StandoutNobel
Complexin Has Opposite Effects on Two Modes of Synaptic Vesicle Fusion
2011
Protein Determinants of SNARE-Mediated Lipid Mixing
2010
LTP Requires a Unique Postsynaptic SNARE Fusion Machinery
2013 StandoutNobel
Complexin Maintains Vesicles in the Primed State in C. elegans
2011
Binding of the complexin N terminus to the SNARE complex potentiates synaptic-vesicle fusogenicity
2010
Synaptic vesicle fusion
2008
Membrane protein sequestering by ionic protein–lipid interactions
2011 StandoutNatureNobel
Complexin Controls Spontaneous and Evoked Neurotransmitter Release by Regulating the Timing and Properties of Synaptotagmin Activity
2012
TANGO1 Facilitates Cargo Loading at Endoplasmic Reticulum Exit Sites
2009 StandoutNobel
Synaptic Vesicles Position Complexin to Block Spontaneous Fusion
2013
Accessory α-Helix of Complexin I Can Displace VAMP2 Locally in the Complexin–SNARE Quaternary Complex
2009
Molecular mechanism of the synaptotagmin–SNARE interaction in Ca2+-triggered vesicle fusion
2010 Nobel
Postsynaptic Complexin Controls AMPA Receptor Exocytosis during LTP
2012 StandoutNobel
Molecular machines governing exocytosis of synaptic vesicles
2012 Nature
Complexin cross-links prefusion SNAREs into a zigzag array
2011 StandoutNobel
For Better or for Worse: Complexins Regulate SNARE Function and Vesicle Fusion
2008
Mechanisms of membrane fusion: disparate players and common principles
2008
A Quaternary SNARE–Synaptotagmin–Ca2+–Phospholipid Complex in Neurotransmitter Release
2007
Complexin Clamps Asynchronous Release by Blocking a Secondary Ca2+ Sensor via Its Accessory α Helix
2010 StandoutNobel
Regulation of Membrane Fusion in Synaptic Excitation-Secretion Coupling: Speed and Accuracy Matter
2007
Molecular form follows function: (un)snaring the SNAREs
2008
v-SNARE Actions during Ca2+-Triggered Exocytosis
2007
Complexin activates and clamps SNAREpins by a common mechanism involving an intermediate energetic state
2011 StandoutNobel
Subtle Interplay between Synaptotagmin and Complexin Binding to the SNARE Complex
2013
Comparative analysis of Drosophila and mammalian complexins as fusion clamps and facilitators of neurotransmitter release
2010
Is Assembly of the SNARE Complex Enough to Fuel Membrane Fusion?
2009
Direct interaction of SNARE complex binding protein synaphin/complexin with calcium sensor synaptotagmin 1
2008
SNARE Protein Mimicry by an Intracellular Bacterium
2008
One SNARE complex is sufficient for membrane fusion
2010
Activity-Dependent IGF-1 Exocytosis Is Controlled by the Ca2+-Sensor Synaptotagmin-10
2011 StandoutNobel
Single Molecule Measurements of Interaction Free Energies Between the Proteins Within Binary and Ternary SNARE Complexes
2009
Tilting the Balance between Facilitatory and Inhibitory Functions of Mammalian and Drosophila Complexins Orchestrates Synaptic Vesicle Exocytosis
2009
Pulling force generated by interacting SNAREs facilitates membrane hemifusion
2009
Complexin and Ca2+ stimulate SNARE-mediated membrane fusion
2008
Complexin Activates Exocytosis of Distinct Secretory Vesicles Controlled by Different Synaptotagmins
2013 StandoutNobel
Mechanisms and Function of Dendritic Exocytosis
2011
A role of complexin–lipid interactions in membrane fusion
2009
Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression
2019 StandoutNobel
Complexin-I Is Required for High-Fidelity Transmission at the Endbulb of Held Auditory Synapse
2009
Single-molecule FRET–derived model of the synaptotagmin 1–SNARE fusion complex
2010 Nobel
Selective Activation of Cognate SNAREpins by Sec1/Munc18 Proteins
2007 StandoutNobel
Munc18/Syntaxin Interaction Kinetics Control Secretory Vesicle Dynamics
2009
A Complexin/Synaptotagmin 1 Switch Controls Fast Synaptic Vesicle Exocytosis
2006 StandoutNobel
Synaptic proteins promote calcium-triggered fast transition from point contact to full fusion
2012 Nobel
Single-Molecule Studies of the Neuronal SNARE Fusion Machinery
2009 Nobel
Exosomes
2019 Standout
Genetic analysis of synaptotagmin-7 function in synaptic vesicle exocytosis
2008 StandoutNobel
The carboxy-terminal domain of complexin I stimulates liposome fusion
2009
Imaging Cell Surface Glycosylation in Vivo Using “Double Click” Chemistry
2013
SNARE bundle and syntaxin N-peptide constitute a minimal complement for Munc18-1 activation of membrane fusion
2010 StandoutNobel
Push-and-pull regulation of the fusion pore by synaptotagmin-7
2010 StandoutNobel
The Detection and Discovery of Glycan Motifs in Biological Samples Using Lectins and Antibodies: New Methods and Opportunities
2015
Synaptotagmin-1 and -7 are functionally overlapping Ca 2+ sensors for exocytosis in adrenal chromaffin cells
2008 StandoutNobel
SNAREpin/Munc18 promotes adhesion and fusion of large vesicles to giant membranes
2008 StandoutNobel
Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals
2022 StandoutNobel
Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice
2008 StandoutNobel
Synaptobrevin N-terminally bound to syntaxin–SNAP-25 defines the primed vesicle state in regulated exocytosis
2010
How Does Synaptotagmin Trigger Neurotransmitter Release?
2008
Imaging bacterial peptidoglycan with near-infrared fluorogenic azide probes
2014 StandoutNobel
Cryo–electron tomography reveals a critical role of RIM1α in synaptic vesicle tethering
2013
Aberrant function and structure of retinal ribbon synapses in the absence of complexin 3 and complexin 4
2009
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
E-Syts, a family of membranous Ca 2+ -sensor proteins with multiple C 2 domains
2007 StandoutNobel
Unsolved Mysteries in Membrane Traffic
2007
Conflicting Views on the Membrane Fusion Machinery and the Fusion Pore
2009
Membrane Fusion: Grappling with SNARE and SM Proteins
2009 StandoutScienceNobel
Neurological Aspects of Human Glycosylation Disorders
2015
Global cancer statistics, 2012
2015 Standout
Discrimination between docking and fusion of liposomes reconstituted with neuronal SNARE-proteins using FCS
2009
Piccolo and bassoon maintain synaptic vesicle clustering without directly participating in vesicle exocytosis
2010 StandoutNobel
Complexins facilitate neurotransmitter release at excitatory and inhibitory synapses in mammalian central nervous system
2008
UNC-18 Promotes Both the Anterograde Trafficking and Synaptic Function of Syntaxin
2008
The Membrane Fusion Enigma: SNAREs, Sec1/Munc18 Proteins, and Their Accomplices—Guilty as Charged?
2012 StandoutNobel
Membranes of the world unite!
2006
Deconstructing complexin function in activating and clamping Ca 2+ -triggered exocytosis by comparing knockout and knockdown phenotypes
2013 StandoutNobel
Minimal membrane docking requirements revealed by reconstitution of Rab GTPase-dependent membrane fusion from purified components
2009
Concurrent Binding of Complexin and Synaptotagmin to Liposome-Embedded SNARE Complexes
2009
Complexin II plays a positive role in Ca 2+ -triggered exocytosis by facilitating vesicle priming
2008
Chemical Glycoproteomics
2016 StandoutNobel
Works of William Eng being referenced
Alternative Zippering as an On-Off Switch for SNARE-Mediated Fusion
2009 StandoutScienceNobel
i-SNAREs
2003
A Clamping Mechanism Involved in SNARE-Dependent Exocytosis
2006 Science
Mapping posttranscriptional regulation of the human glycome uncovers microRNA defining the glycocode
2014
Complex N-Linked Glycans Serve as a Determinant for Exosome/Microvesicle Cargo Recruitment
2014
Molecular imaging using fluorescent lectins permits rapid endoscopic identification of dysplasia in Barrett's esophagus
2012
Energetics and dynamics of SNAREpin folding across lipid bilayers
2007 StandoutNobel
Cross-platform comparison of glycan microarray formats
2014
Distinct Domains of Complexins Bind SNARE Complexes and Clamp Fusion in Vitro
2008 StandoutNobel
Countercurrent Distribution of Two Distinct SNARE Complexes Mediating Transport within the Golgi Stack
2004 StandoutNobel
Identification of a Conserved Glycan Signature for Microvesicles
2011