Standout Papers
Citation Impact
Citing Papers
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Diels-Alder Reaction
2010 StandoutScienceNobel
Innate immune sensing and its roots: the story of endotoxin
2003 StandoutNobel
Completion of the entire hepatitis C virus life cycle in genetically humanized mice
2013 StandoutNatureNobel
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
2018 StandoutNobel
Unidirectional molecular motor on a gold surface
2005 StandoutNatureNobel
Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties
1992 StandoutNobel
Natural adjuvants: Endogenous activators of dendritic cells
1999
The 2–5 A system: Modulation of viral and cellular processes through acceleration of RNA degradation
1998
Molecular Events Mediating T Cell Activation
1990
Intrinsic Immunity Shapes Viral Resistance of Stem Cells
2017 StandoutNobel
Lipopolysaccharide (LPS) recognition in macrophages. Participation of LPS-binding protein and CD14 in LPS-induced adaptation in rabbit peritoneal exudate macrophages.
1993
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
Distinct and Essential Roles of Transcription Factors IRF-3 and IRF-7 in Response to Viruses for IFN-α/β Gene Induction
2000
Extrathymic positive selection of αβ T-cell precursors in nude mice
1992 StandoutNatureNobel
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
Local and Systemic Effects of Intradermal Recombinant Interferon-γ in Patients with Lepromatous Leprosy
1986 StandoutNobel
Protein Denaturation
1968 Standout
A Reversible, Unidirectional Molecular Rotary Motor Driven by Chemical Energy
2005 StandoutScienceNobel
Orally Absorbed Cyclic Peptides
2017
Transcriptional and posttranscriptional regulation of interferon-induced gene expression in human cells
1984
Human lymphotoxin. Production by a lymphoblastoid cell line, purification, and initial characterization.
1984
Control of HLA-A,B,C synthesis and expression in interferon-treated cells.
1982 StandoutNobel
Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene
1998 StandoutScienceNobel
Activation of muscle-specific actin genes in xenopus development by an induction between animal and vegetal cells of a blastula
1985 StandoutNobel
The dsRNA binding protein family: critical roles, diverse cellular functions
2003
Protein Structure Determination in Solution by Nuclear Magnetic Resonance Spectroscopy
1989 StandoutScienceNobel
Cachectin and tumour necrosis factor as two sides of the same biological coin
1986 StandoutNatureNobel
Experimental Determination of the Absolute Enantioselectivity of an Antibody-Catalyzed Diels−Alder Reaction and Theoretical Explorations of the Origins of Stereoselectivity
2003
The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene family
1985 StandoutNobel
The Role of the T3/Antigen Receptor Complex in T-Cell Activation
1986
The Virology and Immunobiology of Lymphocytic Choriomeningitis Virus Infection
1980
At Least Three Human Type α Interferons: Structure of α2
1980 Science
Clonal Deletion Versus Clonal Anergy: The Role of the Thymus in Inducing Self Tolerance
1990 StandoutScienceNobel
The structure of one of the eight or more distinct chromosomal genes for human interferon-α
1980 Nature
Characterization of receptors for immune interferon in U937 cells with 32P-labeled human recombinant immune interferon.
1985
Lymphokine dependence of in vivo expression of MHC class II antigens by endothelium
1985 Nature
A one-plate assay for macrophage bactericidal activity
1985
A family of structural genes for human lymphoblastoid (leukocyte-type) interferon
1980 Nature
Artificial Molecular Rotors
2005
Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development
1993
The human β-interferon gene enhancer is under negative control
1986
Effect of Viral Double-Stranded RNA on Mammalian Cells in Culture: Cytotoxicity Under Conditions Preventing Viral Replication and Protein Synthesis
1973
A novel ras-related gene family
1985 StandoutNobel
The characteristics of inhibition of protein synthesis by double-stranded ribonucleic acid in reticulocyte lysates
1975 StandoutNobel
Cloning and expression of murine immune interferon cDNA.
1983
Novel Proteinaceous Infectious Particles Cause Scrapie
1982 StandoutScienceNobel
Cloning of complementary DNA encoding T-cell replacing factor and identity with B-cell growth factor II
1986 StandoutNatureNobel
Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
2001 StandoutNobel
Cachectin: More Than a Tumor Necrosis Factor
1987 StandoutNobel
Serum β2-microglobulin binds to a T-cell differentiation antigen and increases its expression
1984 StandoutNatureNobel
Foxp3+natural regulatory T cells preferentially form aggregates on dendritic cellsin vitroand actively inhibit their maturation
2008 StandoutNobel
Interferons and tumor necrosis factors have similar catabolic effects on 3T3 L1 cells.
1986
Synthesis in E. coli of a polypeptide with human leukocyte interferon activity
1980 Nature
Human leukocyte interferon: Isolation and characterization of several molecular forms
1981
Pharmacokinetics, single-dose tolerance, and biological activity of recombinant gamma-interferon in cancer patients.
1985
Interferon as a mediator of human lymphocyte suppression.
1980
Treatment of mice with polyinosinic-polycytidilic polyribonucleotide reduces T-cell involvement in a localized inflammatory response to vaccinia virus challenge
1985 StandoutNobel
Kinetics of Folding of Staphylococcal Nuclease
1970 StandoutScienceNobel
PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells
2003 StandoutNobel
Cloning of cDNA encoding the murine IgG1 induction factor by a novel strategy using SP6 promoter
1986 StandoutNatureNobel
Appearance of interferon inducibility and sensitivity during differentiation of murine teratocarcinoma cells in vitro
1978
42 bp element from LDL receptor gene confers end-product repression by sterols when inserted into viral TK promoter
1987 StandoutNobel
Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin
1986 StandoutNatureNobel
Suppression of cell-mediated immunity by street rabies virus.
1977 StandoutNobel
Cross Talk Between Interferon-γ and -α/β Signaling Components in Caveolar Membrane Domains
2000 Science
Interferon-induced inhibition of protein synthesis in L-cell extracts: an ATP-dependent step in the activation of an inhibitor by double-stranded RNA.
1976
Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus
2006 StandoutNobel
Spin—spin coupling and the conformational states of peptide systems
1976
The Induction of Interferon by Natural and Synthetic Polynucleotides
1971
Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase.
1995
Tumour necrosis factors α and β inhibit virus replication and synergize with interferons
1986 Nature
Effect of Interferon-α1 from E. coli on Some Cell Functions
1980 StandoutScienceNobel
Differential Responses to IFN-α Subtypes in Human T Cells and Dendritic Cells
2003
Impact of Protein Kinase PKR in Cell Biology: from Antiviral to Antiproliferative Action
2006
Inducer-responsive expression of the cloned human interferonβ1gene introduced into cultured mouse cells
1982
Controlled transcription of a human α-interferon gene introduced into mouse L cells
1982 Nature
Inducibility of human β-interferon gene in mouse L-cell clones
1982 Nature
Increased sensitivity of cell-free protein synthesis to double-stranded RNA after interferon treatment
1974 Nature
Nuclear Magnetic Resonance Spectroscopy of Amino Acids, Peptides, and Proteins
1970
Identification of two distinct regulatory regions adjacent to the human β-interferon gene
1983
Association between transplantation antigens and a viral membrane protein synthesized from a mammalian expression vector
1983 StandoutNobel
A Macrophage Factor Inhibits Adipocyte Gene Expression: An in Vitro Model of Cachexia
1985 StandoutScienceNobel
The Reliability of Molecular Weight Determinations by Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis
1969 Standout
Phosphorylation of initiation factor eIF-2 and the control of reticulocyte protein synthesis
1977 StandoutNobel
NMR scalar couplings across Watson–Crick base pair hydrogen bonds in DNA observed by transverse relaxation-optimized spectroscopy
1998 StandoutNobel
Role of conserved sequence elements 9L and 2 in self-splicing of the Tetrahymena ribosomal RNA precursor
1986 StandoutNobel
Regulation of the Ets-Related Transcription Factor Elf-1 by Binding to the Retinoblastoma Protein
1993 StandoutScienceNobel
Attenuated T 2 relaxation by mutual cancellation of dipole–dipole coupling and chemical shift anisotropy indicates an avenue to NMR structures of very large biological macromolecules in solution
1997 StandoutNobel
Plant and Animal Sensors of Conserved Microbial Signatures
2010 StandoutScienceNobel
A DNA fragment with an alpha-phosphorothioate nucleotide at one end is asymmetrically blocked from digestion by exonuclease III and can be replicated in vivo.
1981
On the varied biologic effects of interferon
1977
The regulated expression of β-globin genes introduced into mouse erythroleukemia cells
1983 StandoutNobel
Differences in human α- and β-globin gene expression in mouse erythroleukemia cells: The role of intragenic sequences
1984 StandoutNobel
Human nucleotide excision nuclease removes thymine dimers from DNA by incising the 22nd phosphodiester bond 5' and the 6th phosphodiester bond 3' to the photodimer.
1992 StandoutNobel
Works of William E. Stewart being referenced
Specificity of Interferon-induced Enhancement of Toxicity for Double-stranded Ribonucleic Acids
1973
Increased Toxicity of Double-Stranded Ribonucleic Acid in Virus-Infected Animals
1973
Identification of the cell multiplication inhibitory factors in interferon preparations as interferons
1976 Nature
Comparisons of several biological and physicochemical properties of human leukocyte interferons produced by human leukocytes and by E. coli
1980
Elimination of size and charge heterogeneities of human leukocyte interferons by chemical cleavage
1977
Priming: a Nonantiviral Function of Interferon
1971
Human gamma interferon production by leukocytes induced with monoclonal antibodies recognizing T cells.
1981
Cellular Alteration by Interferon: a Virus-Free System for Assaying Interferon
1972
Protective Effects of Tumor Necrosis Factor in Experimental Legionella pneumophila Infections of Mice via Activation of PMN Function
1988
Distinct molecular species of interferons
1974
Proton Nuclear Magnetic Resonance Studies of Model Polypeptides. Aspects of the Helix-Random Coil Interconversion*
1967
The Lymphokines: Biochemistry and Biological Activity
1981
Relative Sensitivities of Viruses to Different Species of Interferon
1969
Increased Susceptibility of Cells Treated with Interferon to the Toxicity of Polyriboinosinic·Polyribocytidylic Acid
1972
The Interferon System
1979
Nuclear magnetic resonance studies of amides
1970 Standout
Molecular heterogeneity of human leukocyte interferon: Two populations differing in molecular weights, requirements for renaturation, and cross-species antiviral activity
1975
Interferon priming. Effects on interferon messenger RNA.
1979
Molecular modification of interferon: Attainment of human interferon in a conformation active on cat cells but inactive on human cells
1976
Differential inactivation and separation of homologous and heterologous antiviral activity of human leukocyte interferon by a proteolytic enzyme
1979
Interferon Production in Hamsters Experimentally Infected with Rabies Virus.
1966
The 13C chemical shift and 13C15N coupling constant of formamide in aqueous solutions
1973
Repeated 'Superinduction' of Interferon in Human Diploid Fibroblast Cultures
1977
Target cell specificity of two species of human interferon-alpha produced in Escherichia coli and of hybrid molecules derived from them.
1981
Effect of glycosylation inhibitors on the production and properties of human leukocyte interferon
1979