Standout Papers
- Antibody to influenza virus matrix protein detects a common antigen on the surface of cells infected with type A influenza viruses. (1977)
- Induction of virus-specific modifications recognized by cytotoxic T cells is not altered by prior substitution of target cells with trinitrophenol. (1977)
- Involvement of H-2L gene products in virus-immune T-cell recognition. Evidence for an H-2L-restricted T-cell response. (1978)
- Cytotoxic T-cell responses in mice infected with influenza and vaccinia viruses vary in magnitude with H-2 genotype. (1978)
Citation Impact
Citing Papers
TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo
2010 StandoutNobel
Differential Antigen Processing by Dendritic Cell Subsets in Vivo
2007 StandoutScienceNobel
Homeostatic maintenance of natural Foxp3 + CD25+ CD4+ regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization
2005 StandoutNobel
MHC-Restricted Cytotoxic T Cells: Studies on the Biological Role of Polymorphic Major Transplantation Antigens Determining T-Cell Restriction-Specificity, Function, and Responsiveness
1979 StandoutNobel
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein
1992 StandoutNatureNobel
Pattern of nucleotide substitution at major histocompatibility complex class I loci reveals overdominant selection
1988 StandoutNature
Peptide-binding specificity of the molecular chaperone BiP
1991 StandoutNatureNobel
The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens
1987 StandoutNature
The antigenic identity of peptide-MHC complexes: A comparison of the conformations of five viral peptides presented by HLA-A2
1993
Neurexins Physically and Functionally Interact with GABAA Receptors
2010 StandoutNobel
Substitution of murine for human CD4 residues identifies amino acids critical for HIV-gp120 binding
1988 Nature
Structure of the human class I histocompatibility antigen, HLA-A2
1987 StandoutNature
The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing
1995 StandoutNatureNobel
Atomic structure of a fragment of human CD4 containing two immunoglobulin-like domains
1990 Nature
Developmental regulation of MHC class II transport in mouse dendritic cells
1997 StandoutNatureNobel
Polypeptide chain binding proteins: Catalysts of protein folding and related processes in cells
1989
Functional sites of human class I MHC molecules: Paradigms a dozen?
1987
Cellular peptide composition governed by major histocompatibility complex class I molecules
1990 Nature
Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
2003 StandoutNatureNobel
Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes
1988 Nature
Recombinant Vaccinia Viruses As Vectors for Studying T Lymphocyte Specificity and Function
1990
The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic route
1990
Influenza virus-infected dendritic cells stimulate strong proliferative and cytolytic responses from human CD8+ T cells.
1994 StandoutNobel
A CD4 domain important for HIV-mediated syncytium formation lies outside the virus binding site
1990
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Crystal structure of an HIV-binding recombinant fragment of human CD4
1990 StandoutNatureNobel
Association of class I major histocompatibility heavy and light chains induced by viral peptides
1989 Nature
Restoring function in exhausted CD8 T cells during chronic viral infection
2005 StandoutNatureNobel
Molecular analysis of the association of HLA-B53 and resistance to severe malaria
1992 Nature
Identification of human CD4 residues affecting class II MHC versus HIV-1 gp120 binding
1989 Nature
Cytotoxic T Lymphocytes in Human Immunodeficiency Virus Infection: Responses to Structural Proteins
1994
Microtubule-dependent retrograde transport of proteins into the ER in the presence of brefeldin a suggests an ER recycling pathway
1990
Selective inhibition of transcytosis by brefeldin A in MDCK cells
1991
Isolation of an endogenously processed immunodominant viral peptide from the class I H–2Kb molecule
1990 Nature
Interaction of the unique N-terminal region of tyrosine kinase p56lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs
1990
Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments
1991 Nature
Dendritic cells and the control of immunity
1998 StandoutNatureNobel
MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding
1991 Nature
Assembly of MHC class I molecules analyzed in vitro
1990
MHC-dependent antigen processing and peptide presentation: Providing ligands for T lymphocyte activation
1994
Autoimmune disease: why and where it occurs
2001
HLA class I-restricted cytotoxic T lymphocytes specific for hepatitis C virus. Identification of multiple epitopes and characterization of patterns of cytokine release.
1995 StandoutNobel
soluble form of CD4 (T4) protein inhibits AIDS virus infection
1988 StandoutNatureNobel
Mechanisms of intracellular protein transport
1994 StandoutNatureNobel
Recognition of pre-processed endogenous antigen by class I but not class II MHC-restricted T cells
1989 Nature
Virus-specific CD8+ T-cell memory determined by clonal burst size
1994 StandoutNatureNobel
T Cell Activation Induces Rapid Tyrosine Phosphorylation of a Limited Number of Cellular Substrates
1989
Neutralization of human T-lymphotropic virus type III by sera of AIDS and AIDS-risk patients
1985 Nature
DECLINING T-CELL IMMUNITY TO INFLUENZA, 1977-82
1983
Major histocompatibility complex class II+B7-1+ tumor cells are potent vaccines for stimulating tumor rejection in tumor-bearing mice.
1995
The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain
1986 StandoutNobel
Influenza virus-specific human cytotoxic T cell clones: Heterogeneity in antigenic specificity and restriction by class II MHC products
1984
Flanking sequences influence the presentation of an endogenously synthesized peptide to cytotoxic T lymphocytes.
1992
Biological properties of an influenza A virus-specific killer T cell clone. Inhibition of virus replication in vivo and induction of delayed-type hypersensitivity reactions.
1981
Genome organization and transactivation of the human immunodeficiency virus type 2
1987 StandoutNatureNobel
Limiting dilution analysis of cytotoxic T lymphocytes to human immunodeficiency virus gag antigens in infected persons: in vitro quantitation of effector cell populations with p17 and p24 specificities.
1991
Inactivated influenza virus, when presented on dendritic cells, elicits human CD8+ cytolytic T cell responses.
1995
Viral Persistence Alters CD8 T-Cell Immunodominance and Tissue Distribution and Results in Distinct Stages of Functional Impairment
2003
The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene family
1985 StandoutNobel
The major histocompatibility complex-restricted antigen receptor on T cells. II. Role of the L3T4 product.
1983
HLA B37 determines an influenza A virus nucleoprotein epitope recognized by cytotoxic T lymphocytes.
1986
Cell Surface Structures Involved in T Cell Activation
1984
Influenza A virus nucleoprotein is a major target antigen for cross-reactive anti-influenza A virus cytotoxic T lymphocytes.
1985
Development of Spontaneous Autoimmune Peripheral Polyneuropathy in B7-2–Deficient Nod Mice
2001
Binding site for human immunodeficiency virus coat protein gp120 is located in the NH2-terminal region of T4 (CD4) and requires the intact variable-region-like domain.
1988
Reconstitution of MHC class I specificity by transfer of the T cell receptor and Lyt-2 genes
1987
The role of L3T4 in recognition of Ia by a cytotoxic, H-2Dd-specific T cell hybridoma.
1984
Differences in antigen presentation to MHC class I-and class II-restricted influenza virus-specific cytolytic T lymphocyte clones.
1986
Murine Major Histocompatibility Complex Class-I Mutants: Molecular Analysis and Structure-Function Implications
1986
Impaired Long-Term Potentiation, Spatial Learning, and Hippocampal Development in fyn Mutant Mice
1992 StandoutScienceNobel
Beta 2-microglobulin is not required for cell surface expression of the murine class I histocompatibility antigen H-2Db or of a truncated H-2Db.
1986
Identification of overlapping HLA class I-restricted cytotoxic T cell epitopes in a conserved region of the human immunodeficiency virus type 1 envelope glycoprotein: definition of minimum epitopes and analysis of the effects of sequence variation.
1992
Type I Diabetes and Multiple Sclerosis Patients Target Islet Plus Central Nervous System Autoantigens; Nonimmunized Nonobese Diabetic Mice Can Develop Autoimmune Encephalitis
2001
Human mumps virus-specific cytotoxic T lymphocytes: Quantitative analysis of HLA restriction
1987
Coat Proteins and Vesicle Budding
1996 StandoutScienceNobel
T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV
1984 StandoutNatureNobel
Inhibition by brefeldin A of a Golgi membrane enzyme that catalyses exchange of guanine nucleotide bound to ARF
1992 StandoutNatureNobel
Selective anergy of V beta 8+ T cells in human immunodeficiency virus-infected individuals.
1994 StandoutNobel
The binding of monoclonal antibodies to cell-surface molecules. A quantitative analysis with immunoglobulin G against two alloantigenic determinants of the human transplantation antigen HLA-A2
1983
The MHC-Binding and gp120-Binding Functions of CD4 Are Separable
1989 Science
Variability and conformation of HLA class I antigens: a predictive approach to the spatial arrangement of polymorphic regions
1984
Reciprocal stimulation of negatively selected high-responder and low-responder T cells in virus-infected recipients.
1979 StandoutNobel
Peptide and nucleotide sequences of rat CD4 (W3/25) antigen: evidence for derivation from a structure with four immunoglobulin-related domains.
1987
Cytotoxic T lymphocytes recognize a fragment of influenza virus matrix protein in association with HLA-A2
1987 Nature
Complete primary structure of a heterodimeric T-cell receptor deduced from cDNA sequences
1984 StandoutNatureNobel
T-cell populations specifically depleted of alloreactive potential cannot be induced to lyse H-2-different virus-infected target cells.
1978 StandoutNobel
Complete sequence of HLA-B27 cDNA identified through the characterization of structural markers unique to the HLA-A, -B, and -C allelic series.
1986
T Cell Subsets and the Recognition of MHC Class
1983
Development and Loss of Virus‐Specific Thymic Competence in Bone Marrow Radiation Chimeras and Normal Mice
1981 StandoutNobel
Dissociation of a 110-kD peripheral membrane protein from the Golgi apparatus is an early event in brefeldin A action.
1990
Brefeldin A, a drug that blocks secretion, prevents the assembly of non-clathrin-coated buds on Golgi cisternae
1991 StandoutNobel
Structural analysis of an HLA-B27 functional variant: identification of residues that contribute to the specificity of recognition by cytolytic T lymphocytes.
1985
Cytotoxic T-Cell Immunity to Influenza
1983
Synthetic CD4 Peptide Derivatives That Inhibit HIV Infection and Cytopathicity
1988 Science
Normal Development of Mice Deficient in β 2 M, MCClass I Proteins, and CD8 + T Cells
1990 StandoutScienceNobel
Major histocompatibility antigens: The human (HLA-A,-B,-C) and murine (H-2K, H-2D) class I molecules
1981
Vaccinia-specific cytotoxic T-cell responses in the context of H-2 antigens not encountered in thymus may reflect aberrant recognition of a virus-H-2 complex.
1979 StandoutNobel
Identification of viral molecules recognized by influenza-specific human cytotoxic T lymphocytes.
1987
The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody.
1983
Protein Sorting by Transport Vesicles
1996 StandoutScienceNobel
The class II molecules of the human and murine major histocompatibility complex
1984
The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus
1984 StandoutNature
Tumor Rejection After Direct Costimulation of CD8 + T Cells by B7-Transfected Melanoma Cells
1993 StandoutScienceNobel
Recognition of Influenza A Virus Nucleoprotein by Human Cytotoxic T Lymphocytes
1986
Heterologous Protection Against Influenza by Injection of DNA Encoding a Viral Protein
1993 StandoutScience
Localization of TGN38 to the trans-Golgi network: involvement of a cytoplasmic tyrosine-containing sequence.
1993
Antigen processing by epidermal Langerhans cells correlates with the level of biosynthesis of major histocompatibility complex class II molecules and expression of invariant chain.
1990 StandoutNobel
Structural Analysis of the Functional Sites of Class I HLA Antigens
1985
Identification of a 140‐kDa activation antigen as a target structure for a series of human cloned natural killer cell lines
1984
CD8+ T cell recognition of an endogenously processed epitope is regulated primarily by residues within the epitope.
1992 StandoutNobel
Hepatitis C virus (HCV)-specific cytotoxic T lymphocytes recognize epitopes in the core and envelope proteins of HCV
1993 StandoutNobel
The T cell differentiation antigen Leu-2/T8 is homologous to immunoglobulin and T cell receptor variable regions
1985
Brefeldin A: insights into the control of membrane traffic and organelle structure.
1992 Standout
Different rules govern help for cytotoxic T cells and B cells
1978 StandoutNatureNobel
Vaccinia virus-specific CD8+ cytotoxic T lymphocytes in humans
1993
Developmentally ordered appearance of thymocytes expressing different T-cell antigen receptors
1988 StandoutNatureNobel
Patterns of virus-immune T-cell responsiveness. Comparison of (H-2(k) x H-2(b)) {arrow} H-2(b) Radiation Chimeras and negatively selected H-2(b) lymphocytes
1979 StandoutNobel
Structural analysis of the human immunodeficiency virus-binding domain of CD4. Epitope mapping with site-directed mutants and anti-idiotypes.
1989
Enhancement of Antitumor Immunity by CTLA-4 Blockade
1996 StandoutScienceNobel
A transposable epitope of HLA-137, B40 molecules
1987
Molecular Biology of Prion Diseases
1991 StandoutScienceNobel
Relationship between Human T Cell Functional Heterogeneity and Human T Cell Surface Molecules
1983
Exon shuffling in vivo can generate novel HLA class I molecules.
1985
The Antigen-Specific, Major Histocompatibility Complex-Restricted Receptor on T Cells
1986
Monoclonal antibodies to LFA-1 and to CD4 inhibit the mixed leukocyte reaction after the antigen-dependent clustering of dendritic cells and T lymphocytes.
1987 StandoutNobel
The isolation and sequence of the gene encoding T8: A molecule defining functional classes of T lymphocytes
1985
The HLA-AW24 gene: Sequence, surroundings and comparison with the HLA-A2 and HLA-A3 genes
1985
Distinct influences of peptide-MHC quality and quantity on in vivo T-cell responses
2012 StandoutNobel
CELL BIOLOGY OF ANTIGEN PROCESSING IN VITRO AND IN VIVO
2005
Coatomer Interaction with Di-Lysine Endoplasmic Reticulum Retention Motifs
1994 Science
Works of William E. Biddison being referenced
Delineation of immunologically and biochemically distinct HLA-A2 antigens.
1982
Processing pathways for presentation of cytosolic antigen to MHC class II-restricted T cells
1992 Nature
Brefeldin A implicates egress from endoplasmic reticulum in class I restricted antigen presentation
1989 Nature
Accumulation of human immunodeficiency virus‐specific cytotoxic T lymphocytes away from the predominant site of virus replication during primary infection
1997
Skewed T-cell receptor repertoire in genetically identical twins correlates with multiple sclerosis
1993 Nature
TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways
2003
Class II MHC molecules can use the endogenous pathway of antigen presentation
1990 Nature
A Monoclonal Antibody 7G7/B6, Binds to an Epitope on the Human Interleukin-2 (IL-2) Receptor That is Distinct From That Recognized by IL-2 or Anti-Tac
1985
HLA-B37 and HLA-A2.1 molecules bind largely nonoverlapping sets of peptides.
1990
HLA-linked genetic control of the specicity of human cytotoxic T-cell responses to influenza virus.
1979
Induction of virus-specific modifications recognized by cytotoxic T cells is not altered by prior substitution of target cells with trinitrophenol.
1977 StandoutNobel
Influenza virus-specific cytotoxic T cells are restricted by multiple HLA-A3-related self antigens: evidence for recognition of distinct self structures in conjunction with different foreign antigens.
1981
Involvement of H-2L gene products in virus-immune T-cell recognition. Evidence for an H-2L-restricted T-cell response.
1978 StandoutNobel
Virus-immune cytotoxic T cells recognize structural differences between serologically indistinguishable HLA-A2 molecules
1980
Subtypes of HLA-B27 detected by cytotoxic T lymphocytes and their role in self-recognition
1982
Two subgroups of HLA Bw44 defined by cell-mediated lympholysis that differ in Bw44 expression on platelets and in patterns of genetic linkage disequilibrium.
1982
Presentation of three different viral peptides, HTLV-1 Tax, HCMV gB, and influenza virus M1, is determined by common structural features of the HLA-A2.1 molecule
1992
Endogenous peptides bound to HLA-A3 possess a specific combination of anchor residues that permit identification of potential antigenic peptides.
1993
Comparative structural analysis of HLA-A2 antigens distinguishable by cytotoxic T lymphocytes: variants M7 and DR1
1982
Possible involvement of the T4 molecule in T cell recognition of class II HLA antigens. Evidence from studies of CTL-target cell binding.
1984
Sequence motifs important for peptide binding to the human MHC class I molecule, HLA-A2.
1992
Human cytotoxic T-cell responses to type A and type B influenza viruses can be restricted by different HLA antigens. Implications for HLA polymorphism and genetic regulation.
1980
Analysis of the molecular basis of HLA-A3 recognition by cytotoxic T cells using defined mutants of the HLA-A3 molecule.
1988
Mutations in the alpha 2 helix of HLA-A2 affect presentation but do not inhibit binding of influenza virus matrix peptide.
1988
Comparative structural analysis of HLA-A3 antigens distinguishable by cytotoxic T lymphocytes: variant E1.
1985
Antibody to influenza virus matrix protein detects a common antigen on the surface of cells infected with type A influenza viruses.
1977 StandoutNobel
T cell subpopulations required for the human cytotoxic T lymphocyte response to influenza virus: evidence for T cell help.
1981
Cytotoxic T-cell responses in mice infected with influenza and vaccinia viruses vary in magnitude with H-2 genotype.
1978 StandoutNobel
Comparative structural analysis of HLA-A2 antigens distinguishable by cytotoxic T lymphocytes. II. Variant DK1: evidence for a discrete CTL recognition region.
1983
The role of the human major histocompatibility complex in cytotoxic T-cell responses to virus-infected cells
1982
Soluble interleukin 2 receptors are released from activated human lymphoid cells in vitro.
1985
Differences in HLA Antigen Recognition by Human Influenza Virus-Immune Cytotoxic T Cells
1979
Specificity of peptide binding by the HLA-A2.1 molecule.
1989
Assembly, specific binding, and crystallization of a human TCR-alphabeta with an antigenic Tax peptide from human T lymphotropic virus type 1 and the class I MHC molecule HLA-A2.
1996
DNA sequence of HLA-A11: Remarkable homology with HLA-A3 allows identification of residues involved in epitopes recognized by antibodies and T cells
1987
Prospective study of cytotoxic T lymphocyte responses to influenza and antibodies to human T lymphotropic virus-III in homosexual men. Selective loss of an influenza-specific, human leukocyte antigen-restricted cytotoxic T lymphocyte response in human T lymphotropic virus-III positive individuals with symptoms of acquired immunodeficiency syndrome and in a patient with acquired immunodeficiency syndrome.
1985
Possible involvement of the OKT4 molecule in T cell recognition of class II HLA antigens. Evidence from studies of cytotoxic T lymphocytes specific for SB antigens.
1982
Clustering of non-major histocompatibility complex susceptibility candidate loci in human autoimmune diseases
1998
Possible involvement of the T4 molecule in T cell recognition of class II HLA antigens: evidence from studies of proliferative responses to SB antigens.
1983
Overlapping epitopes that are recognized by CD8+ HLA class I-restricted and CD4+ class II-restricted cytotoxic T lymphocytes are contained within an influenza nucleoprotein peptide
1992
Measles virus-specific T4+ human cytotoxic T cell clones are restricted by class II HLA antigens.
1984
Specific lysis of human immunodeficiency virus type 1-infected cells by a HLA-A3.1-restricted CD8+ cytotoxic T-lymphocyte clone that recognizes a conserved peptide sequence within the gp41 subunit of the envelope protein.
1991
Phenotypes of human natural killer cell populations detected with monoclonal antibodies.
1981
The self determinants recognized by human virus-immune T cells can be distinguished from the serologically defined HLA antigens.
1980
Virus Specificity of Human Influenza Virus-Immune Cytotoxic T Cells
1979
Tyrosine phosphorylation of the human T cell antigen receptor zeta-chain: activation via CD3 but not CD2.
1988