Citation Impact
Citing Papers
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
Origins of catalysis by computationally designed retroaldolase enzymes
2010 StandoutNobel
Mechanism-based isocoumarin inhibitors for trypsin and blood coagulation serine proteases: new anticoagulants
1988
Kinetic properties of the binding of .alpha.-lytic protease to peptide boronic acids
1988
Synthesis and Kinetic Studies of Diphenyl 1-(N-Peptidylamino)alkanephosphonate Esters and Their Biotinylated Derivatives as Inhibitors of Serine Proteases and Probes for Lymphocyte Granzymes
1997
Synthetic Inhibitors of Elastase
1994
Dual Detection of Fungal Infections in Drosophila via Recognition of Glucans and Sensing of Virulence Factors
2006 StandoutNobel
A protein-conducting channel in the endoplasmic reticulum
1991 StandoutNobel
α -Aminoalkylphosphonate DI(Chlorophenyl) Esters as Inhibitors of Serine Proteases
1994
A Novel Chitinase Inhibitor from a Marine Bacterium, Pseudomonassp.
1996
Network antibodies identify nuclear lamin B as a physiological attachment site for peripherin intermediate filaments
1991 StandoutNobel
Dipeptide Phosphonates as Inhibitors of Dipeptidyl Peptidase IV
1994
Novel amidine-containing peptidyl phosphonates as irreversible inhibitors for blood coagulation and related serine proteases
1994
Engineered Metal-Binding Proteins: Purification to Protein Folding
1991 StandoutScienceNobel
Polycystic Ovary Syndrome
1995 Standout
[31] Isocoumarin inhibitors of serine peptidases
1994
Fluorescent Derivatives of Diphenyl [1-(N-Peptidylamino)alkyl]phosphonate Esters: Synthesis and Use in the Inhibition and Cellular Localization of Serine Proteases
1994
Regulation of serine protease activity by an engineered metal switch
1990
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Localization of newly synthesized vimentin subunits reveals a novel mechanism of intermediate filament assembly
1990
Cysteinyl Proteinases and Their Selective Inactivation
1990
Irreversible inhibition of serine proteases by peptidyl derivatives of α-aminoalkylphosphonate diphenyl esters
1989
A protein-folding reaction under kinetic control
1992 StandoutNatureNobel
bottleneck acts as a regulator of the microfilament network governing cellularization of the Drosophila embryo
1993 StandoutNobel
Crystal Structure of the Hepatitis C Virus NS3 Protease Domain Complexed with a Synthetic NS4A Cofactor Peptide
1996 StandoutNobel
Introduction of a cysteine protease active site into trypsin
1989
Biotinylated isocoumarins, new inhibitors and reagents for detection, localization, and isolation of serine proteases
1993
Inhibitors of trypsin-like serine proteases prevent DNA damage-induced neuronal death by acting upstream of the mitochondrial checkpoint and of p53 induction
2001
Assessment of CAPRI predictions in rounds 3–5 shows progress in docking procedures
2005
The nematophagous fungus Verticillium chlamydosporium produces a chymoelastase-like protease which hydrolyses host nematode proteins in situ
1994
Reaction of porcine pancreatic elastase with 7-substituted 3-alkoxy-4-chloroisocoumarins: design of potent inhibitors using the crystal structure of the complex formed with 4-chloro-3-ethoxy-7-guanidinoisocoumarin
1990
Inhibition of human leukocyte elastase, cathepsin G, chymotrypsin A.alpha., and porcine pancreatic elastase with substituted isobenzofuranones and benzopyrandiones
1985
Cardiovascular mortality and noncontraceptive use of estrogen in women: results from the Lipid Research Clinics Program Follow-up Study.
1987 Standout
Structural patterns in globular proteins
1976 StandoutNatureNobel
Near-native structure refinement using in vacuo energy minimization
2007 StandoutNobel
Distributions of pancreatic ribonuclease, chymotrypsin, and trypsin in vertebrates
1967
Basal release of nitric oxide from aortic rings is greater in female rabbits than in male rabbits: implications for atherosclerosis.
1992 StandoutNobel
Epidermal Growth Factor: High and Low Molecular Weight Forms
1970 StandoutNobel
MICROTUBULE PROTEIN POOLS IN EARLY DEVELOPMENT*
1975
Microtubule arrays present during the syncytial and cellular blastoderm stages of the early Drosophila embryo
1986
Antibodies to “Alcalase” after Industrial Exposure
1971 StandoutNobel
The Catalytic Role of the Active Site Aspartic Acid in Serine Proteases
1987 Science
On the irreversible inhibition of α-chymotrypsin, trypsin, pancreatic kallikrein', thrombin and elastase by N-(β-pyridylmethyl)-3,4 dichlorophenoxyacetamide-p-fluorosulfonylacetanilide bromide
1973
Affinity Labelling of Antibodies with Aryl Nitrene as Reactive Group
1969 StandoutNatureNobel
DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8 + T cells in a spectrum of human MHC I haplotypes
2007 StandoutNobel
Inhibition de l'élastase leucocytaire humaine: inhibition par des céphalosporines sulfones substituées sur le C-2
1989
The reaction of an α-aza-amino acid derivative with chymotrypsin and its use as a ligand for covalent affinity purification
1974
Enhanced visibility of hydrogen atoms by neutron crystallography on fully deuterated myoglobin
2000 StandoutNobel
PHOTOREGULATION OF BIOLOGICAL ACTIVITY BY PHOTOCROMIC REAGENTS, II. INHIBITORS OF ACETYLCHOLINESTERASE
1969
Identity of the tryptic and α-chymotrypic reactive sites on soybean trypsin inhibitor (Kunitz)
1972
SOMATIC RECOMBINATION OF DUPLICATED GENES: AN HYPOTHESIS ON THE ORIGIN OF ANTIBODY DIVERSITY
1967 StandoutNobel
THE COVALENT STRUCTURE OF AN ENTIRE γG IMMUNOGLOBULIN MOLECULE
1969 StandoutNobel
Immunoglobulins: Chemical Typing of Immunoglobulins
1969 StandoutNatureNobel
THE STRUCTURE OF CARBOXYPEPTIDASE A, VI. SOME RESULTS AT 2.0-Å RESOLUTION, AND THE COMPLEX WITH GLYCYL-TYROSINE AT 2.8-Å RESOLUTION
1967 StandoutNobel
The Three-Dimensional Structure of Asn 102 Mutant of Trypsin: Role of Asp 102 in Serine Protease Catalysis
1987 Science
Immunological cross-reaction between trypsin and chymotrypsin as a guide to structural homology
1970
Chromatin structure as probed by nucleases and proteases: Evidence for the central role of hitones H3 and H4
1976
Mapping the extended substrate binding site of cathepsin G and human leukocyte elastase. Studies with peptide substrates related to the alpha 1-protease inhibitor reactive site.
1979
Antibodies Reactive with Native Lysozyme Elicited by a Completely Synthetic Antigen
1971 StandoutNobel
Alkylation of a Histidine Residue at the Active Site of Bovine Pancreatic Deoxyribonuclease
1969 StandoutNobel
Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A
2011 StandoutNobel
Structure of Antibody Molecules
1967 StandoutNatureNobel
Preparation and Chemical Properties of Purified Stem and Fruit Bromelains*
1964 StandoutNobel
Reaction of serine proteases with substituted isocoumarins: discovery of 3,4-dichloroisocoumarin, a new general mechanism based serine protease inhibitor
1985
β 2 -Microglobulin—A Free Immunoglobulin Domain
1972 StandoutNobel
Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
1979 Standout
Diethylpyrocarbonate inhibition of estrogen binding to rat alpha-fetoprotein: Evidence that one or more histidine residues regulate estrogen binding
1981
ARTIFICIAL LIGHT‐SENSITIVE ENZYMATIC SYSTEMS AS CHEMICAL AMPLIFIERS OF WEAK LIGHT SIGNALS
1979
Reaction of serine proteases with substituted 3-alkoxy-4-chloroisocoumarins and 3-alkoxy-7-amino-4-chloroisocoumarins: new reactive mechanism-based inhibitors
1985
Inactivation of Chymotrypsin by Cyanate
1964 StandoutNobel
Structural associations of synemin and vimentin filaments in avian erythrocytes revealed by immunoelectron microscopy
1982
Conformational changes resulting from the carbazoylation of bovine α-chymotrypsin by p-nitrophenyl N2-acetyl-N1-arylmethylcarbazates
1977
Challenges in the computational design of proteins
2009
Functional Tyrosyl Residues in the Active Center of Bovine Pancreatic Carboxypeptidase A*
1963
Allosteric Activation of the Hydrolysis of Specific Substrates by Chymotrypsin
1976
Antibody Active Sites and Immunoglobulin Molecules
1966 Science
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Substrate specificity of two chymotrypsin-like proteases from rat mast cells. Studies with peptide 4-nitroanilides and comparison with cathepsin G
1980
Polypeptide Chains of Immunoglobulins from the Smooth Dogfish ( Mustelus canis )
1966 StandoutScienceNobel
Reversible Chemical Modification of the Scrapie Agent
1981 StandoutScienceNobel
Subunit interaction and enzymic activity of mouse 7S nerve growth factor
1969
Progress in Modeling of Protein Structures and Interactions
2005 StandoutScienceNobel
Granzymes (lymphocyte serine proteases): characterization with natural and synthetic substrates and inhibitors
2000
Disulphide Bridges of Immunoglobin G1 Heavy Chains
1967 StandoutNatureNobel
A Prospective Study of Postmenopausal Estrogen Therapy and Coronary Heart Disease
1985
Cross-linking of DNA with trimethylpsoralen is a probe for chromatin structure
1977 StandoutNobel
New proteolytic enzymes in yeast
1981
Somatic Translocation of Antibody Genes
1970 StandoutNatureNobel
Affinity Labeling of the Active Site of Staphylococcal Nuclease
1969 StandoutNobel
Alkyl isocyanates as active-site-specific reagents for serine protease. Identification of the active-site serine as the site of reaction
1973
Electrostatic Basis for Enzyme Catalysis
2006 StandoutNobel
Structure of nucleosome core particles of chromatin
1977 StandoutNatureNobel
Mammalian chymotrypsin-like enzymes. Comparative reactivities of rat mast cell proteases, human and dog skin chymases, and human cathepsin G with peptide 4-nitroanilide substrates and with peptide chloromethyl ketone and sulfonyl fluoride inhibitors
1985
Increased Incidence of Coronary Heart Disease in Women Castrated Prior to the Menopause
1959
Cyclin: A protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division
1983 StandoutNobel
The Structure of Papain
1971 Standout
Structure of Subtilisin BPN′ at 2.5 Å Resolution
1969 Nature
Myocardial Infarction and Estrogen Therapy in Post-Menopausal Women
1976
[16] Reaction of serine proteases with halomethyl ketones
1977
Relationship of nuclear membranes with filaments and microtubules
1971
Domains and the hinge region of an immunoglobulin heavy chain are encoded in separate DNA segments
1979 StandoutNatureNobel
Isolation of the putative structural gene for the lysine-arginine-cleaving endopeptidase required for processing of yeast prepro-α-factor
1984 StandoutNobel
The Complete Amino Acid Sequence of Two Types of Subtilisin, BPN' and Carlsberg
1966
Brain aminoacyl arylamidase. Further purification of the soluble bovine enzyme and studies on substrate specificity and possible active-site residues
1970
Sulfonyl Fluorides as Inhibitors of Esterases. III. Identification of Serine as the Site of Sulfonylation in Phenylmethanesulfonyl α-Chymotrypsin*
1965
The Reliability of Molecular Weight Determinations by Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis
1969 Standout
Direct determination of the protonation states of aspartic acid-102 and histidine-57 in the tetrahedral intermediate of the serine proteases: neutron structure of trypsin
1981
The dissociation of nuclear and centrosomal division in gnu, a mutation causing giant nuclei in Drosophila
1986 StandoutNobel
Time interval from castration in premenopausal women to development of excessive coronary atherosclerosis
1967
Chemical modification of papain
1968 Standout
High-resolution structures of a chitinase complexed with natural product cyclopentapeptide inhibitors: Mimicry of carbohydrate substrate
2002 StandoutNobel
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
Evidence that the N-terminal domain of nonstructural protein NS3 from yellow fever virus is a serine protease responsible for site-specific cleavages in the viral polyprotein.
1990 StandoutNobel
Menopause and Risk of Cardiovascular Disease
1976 Standout
Works of William Cohen being referenced
Observations of the marginal band system of nucleated erythrocytes.
1978
Automatic Sequence Design of Major Histocompatibility Complex Class I Binding Peptides Impairing CD8+ T Cell Recognition
2003
The preparation and properties of two new chromogenic substrates of trypsin
1961 Standout
The presence of a second conformation-sensitive functional group at the active center of chymotrypsin
1961
An estimate of the amount of microtubule protein in the isolated mitotic apparatus
1970
Studies on the Reactivation of Diethylphosphorylchymotrypsin1
1960
Hereditary factors in the Stein-Leventhal syndrome
1968
Mitotic spindles of Drosophila melanogaster: A phase-contrast and scanning electron-microscope study
1977
Evidence for an Active-Center Histidine in Trypsin through Use of a Specific Reagent, 1-Chloro-3-tosylamido-7-amino-2-heptanone, the Chloromethyl Ketone Derived from Nα-Tosyl-L-lysine*
1965
Mitotic spindles from Drosophila melanogaster embryos
1973
A Kinetic Analysis of the Papain-Catalyzed Hydrolysis of α-N-Benzoyl-L-citrulline Methyl Ester*
1967
EFFECTS OF LONG-TERM ADMINISTRATION OF ESTROGENS ON SERUM LIPIDS OF POSTMENOPAUSAL WOMEN
1961
The Inactivation of Chymotrypsin by Diphenylcarbamyl Chloride and Its Reactivation by Nucleophilic Agents*
1966
Effects of Long-Term Administration of Estrogens on Serum Lipids of Postmenopausal Women
1960
Dendritic cells cross-present HIV antigens from live as well as apoptotic infected CD4 + T lymphocytes
2004
Effects of Estrogen Therapy on Hormonal Functions and Serum Lipids in Men with Coronary Atherosclerosis
1956
Increased Incidence of Cardiovascular Disease in Castrated Women
1963
Specific Inactivation of Chymotrypsin by Diphenylcarbamyl Chloride
1963
ESTROGEN REPLACEMENT THERAPY IN WOMEN WITH CORONARY ATHEROSCLEROSIS
1958