Standout Papers
Citation Impact
Citing Papers
TRPA1 mediates spinal antinociception induced by acetaminophen and the cannabinoid Δ9-tetrahydrocannabiorcol
2011 Standout
AdipoQ Is a Novel Adipose-specific Gene Dysregulated in Obesity
1996 Standout
Discovery of “Self-Synergistic” Spinal/Supraspinal Antinociception Produced by Acetaminophen (Paracetamol)
2000
Role of melanocortinergic neurons in feeding and the agouti obesity syndrome
1997 StandoutNature
Decreased opioid-induced antinociception but unaltered G-protein activation in the genetic-diabetic NOD mouse
2000
The μ-opioid receptor is necessary for [d-Pen2,d-Pen5]enkephalin-induced analgesia
1997
15-Deoxy-Δ12,14-Prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ
1995 Standout
Characteristics and common properties of inhibitors, inducers, and activators of CYP enzymes
2002
Muscarinic Supersensitivity and Impaired Receptor Desensitization in G Protein–Coupled Receptor Kinase 5–Deficient Mice
1999 StandoutNobel
Identification and expression cloning of a leptin receptor, OB-R
1995 Standout
Rethinking amide bond synthesis
2011 StandoutNature
Congenital leptin deficiency is associated with severe early-onset obesity in humans
1997 StandoutNature
Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus
2001 StandoutNature
Recombinant Mouse OB Protein: Evidence for a Peripheral Signal Linking Adiposity and Central Neural Networks
1995 StandoutScience
Centrally administered CCK-8 suppresses activity in mice by a “peripheral-type” CCK receptor
1989
Relationships between intracellular vitamin E, lipid peroxidation, and chemical toxicity in hepatocytes
1988
Pharmacological characterization of morphine-6-sulfate and codeine-6-sulfate
1999
Mechanical, thermal and formalin-induced nociception is differentially altered in 5-HT1A−/−, 5-HT1B−/−, 5-HT2A−/−, 5-HT3A−/− and 5-HTT−/− knock-out male mice
2007 StandoutNobel
Characterization of mechanical withdrawal responses and effects of μ-, δ- and κ-opioid agonists in normal and μ-opioid receptor knockout mice
1999
Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
1995 Standout
Serum Immunoreactive-Leptin Concentrations in Normal-Weight and Obese Humans
1996 Standout
Targeted Disruption of the Melanocortin-4 Receptor Results in Obesity in Mice
1997 Standout
Nitric oxide synthases: structure, function and inhibition
2001 Standout
Retention of Supraspinal Delta-like Analgesia and Loss of Morphine Tolerance in δ Opioid Receptor Knockout Mice
1999
Enhanced Leptin-Stimulated Pi3k Activation in the CNS Promotes White Adipose Tissue Transdifferentiation
2007 StandoutNobel
Central nervous system control of food intake
2000 StandoutNature
TRPM8 Is Required for Cold Sensation in Mice
2007 StandoutNobel
Interactions between laudanosine, GABA, and opioid subtype receptors: implication for laudanosine seizure activity
1994
Abnormal splicing of the leptin receptor in diabetic mice
1996 StandoutNature
G‐protein receptor kinase 3 (GRK3) influences opioid analgesic tolerance but not opioid withdrawal
2004 StandoutNobel
MIF as a glucocorticoid-induced modulator of cytokine production
1995 StandoutNature
Obesity as a medical problem
2000 StandoutNature
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
2012 StandoutNatureNobel
High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal
2005 Standout
Menthol: a natural analgesic compound
2002
The hormone resistin links obesity to diabetes
2001 StandoutNature
A potent and selective endogenous agonist for the µ-opiate receptor
1997 Nature
The biopsychosocial approach to chronic pain: Scientific advances and future directions.
2007 Standout
A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
1998 StandoutNature
Obesity and the Regulation of Energy Balance
2001 Standout
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
2017 Standout
Leptin and the regulation of body weight in mammals
1998 StandoutNature
Effect of pertussis toxin on morphine, diphenhydramine, baclofen, clomipramine and physostigmine antinociception
1996
Theoretical Basis, Experimental Design, and Computerized Simulation of Synergism and Antagonism in Drug Combination Studies
2006 Standout
The inflammatory reflex
2002 StandoutNature
Synthetic therapeutic peptides: science and market
2009
Diet-induced obese mice develop peripheral, but not central, resistance to leptin.
1997
Role of leptin in the neuroendocrine response to fasting
1996 StandoutNature
A role for glucagon-like peptide-1 in the central regulation of feeding
1996 StandoutNature
Obesity and insulin resistance
2000 Standout
Evidence That the Diabetes Gene Encodes the Leptin Receptor: Identification of a Mutation in the Leptin Receptor Gene in db/db Mice
1996 Standout
Enhanced Morphine Analgesia in Mice Lacking β-Arrestin 2
1999 StandoutScienceNobel
Lack of Morphine and Enkephalin Tolerance in 129/SvEv Mice: Evidence for a NMDA Receptor Defect
1998
Studies on the mechanism of chlorpromazine protection against Brucella endotoxin in mice.
1957
Synthesis of Heterocycles via Electrophilic Cyclization of Alkynes Containing Heteroatom
2011 Standout
HMGB-1, A DNA-BINDING PROTEIN WITH CYTOKINE ACTIVITY, INDUCES BRAIN TNF AND IL-6 PRODUCTION, AND MEDIATES ANOREXIA AND TASTE AVERSION
2002
beta-endorphin is a potent analgesic agent.
1976
Activity of the δ-Opioid Receptor Is Partially Reduced, Whereas Activity of the κ-Receptor Is Maintained in Mice Lacking the μ-Receptor
1998
[1] Role of free radicals and catalytic metal ions in human disease: An overview
1990 Standout
μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence
2000 StandoutNatureNobel
IL-6 is essential in TNF-α-induced fever
1998
Endorphins: Profound Behavioral Effects in Rats Suggest New Etiological Factors in Mental Illness
1976 StandoutScienceNobel
On the biological activities of the synthetic tetrapeptide pyroglutamyl-tyrosyl-arginyl-tryptophanyl-amide
1972 StandoutNobel
Mechanism of Molybdenum Nitrogenase
1996 Standout
Pituitary and Gonadal Hormones in Women during Spontaneous and Induced Ovulatory Cycles
1970
Nuclear Magnetic Resonance Spectra of Adenosine Di- and Triphosphate
1962
Brown Adipose Tissue: Function and Physiological Significance
2004 Standout
Foot-shock induced stress increases β-endorphin levels in blood but not brain
1977 StandoutNatureNobel
Passage of circulating adrenaline into perfused cerebral ventricles and subarachnoidal space
1960
Intracerebroventricular injections in mice
1986
Behavioral effects of intracerebroventricularly administered neurohypophyseal hormone analogs in mice
1982
[(3-Chlorophenyl)piperazinylpropyl]pyridazinones and Analogues as Potent Antinociceptive Agents
2003
THE UPTAKE OF CIRCULATING [3H]NOREPINEPHRINE BY THE PITUITARY GLAND AND VARIOUS AREAS OF THE BRAIN
1961 StandoutNobel
The Oxytocin Receptor System: Structure, Function, and Regulation
2001 Standout
Inhibition of acute inflammation in the periphery by central action of salicylates.
1991
Effects of the obese Gene Product on Body Weight Regulation in ob / ob Mice
1995 StandoutScience
Functionally differentiating two neuronal nitric oxide synthase isoforms through antisense mapping: Evidence for opposing NO actions on morphine analgesia and tolerance
1997
Neuronal actions of endorphins and enkephalins among brain regions: a comparative microiontophoretic study.
1977 StandoutNobel
Regulation of glutaminase B in Escherichia coli. III. Control by nucleotides and divalent cations.
1976 StandoutNobel
Works of WF McCormick being referenced
PHARMACOLOGICAL EFFECTS PRODUCED BY INTRACEREBRAL INJECTION OF DRUGS IN THE CONSCIOUS MOUSE
1957 Standout
Rotatory dispersion of inosine triphosphate and the influence of metals on ITP and ATP
1959
Effect of Chlorpromazme on Survival Time in Irradiated Mice.
1955
Influence of Water-Soluble Vitamin E on Survival Time in Irradiated Mice
1954 Science
PATTERNS OF URINARY FSH EXCRETION DURING OVULATORY AND ANOVULATORY MENSTRUAL CYCLES
1968
A Fatal Drug Interaction Between Clozapine and Fluoxetine
1998