Citation Impact
Citing Papers
Cardiac Hypertrophy: The Good, the Bad, and the Ugly
2003 Standout
Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases
2011 Standout
Dual Role of Mitochondrial Reactive Oxygen Species in Hypoxia Signaling: Activation of Nuclear Factor-κB via c-SRC– and Oxidant-Dependent Cell Death
2007
Reactive Oxygen Species in Inflammation and Tissue Injury
2013 Standout
Hydrogen peroxide as a central redox signaling molecule in physiological oxidative stress: Oxidative eustress
2017 Standout
Signaling from β1- and β2-adrenergic receptors is defined by differential interactions with PDE4
2008 StandoutNobel
Ginsenoside Rb1 Reduces Isoproterenol-Induced Cardiomyocytes ApoptosisIn VitroandIn Vivo
2013
A review on plant-based rutin extraction methods and its pharmacological activities
2013 Standout
Cardiac-specific blockade of NF-κB in cardiac pathophysiology: differences between acute and chronic stimuli in vivo
2005
Traditional Chinese Medicine for Cardiovascular Disease
2017 Standout
Effects of Flavonoids and other Polyphenols on Inflammation
2011 Standout
Molecular dissection of reactive astrogliosis and glial scar formation
2009 Standout
Role of the BMK1/ERK5 signaling pathway: lessons from knockout mice
2004
Lipopolysaccharide signaling in endothelial cells
2005
Pathological roles of MAPK signaling pathways in human diseases
2010 Standout
Signal integration by JNK and p38 MAPK pathways in cancer development
2009 Standout
PKG activity causes photoreceptor cell death in two retinitis pigmentosa models
2008
Vascular shear stress and activation of inflammatory genes
2006
Ameliorating effects of compounds derived from Salvia miltiorrhiza root extract on microcirculatory disturbance and target organ injury by ischemia and reperfusion
2007 Standout
Heme oxygenase and carbon monoxide initiate homeostatic signaling
2007
Crosstalk of reactive oxygen species and NF-κB signaling
2010 Standout
Mammalian phosphoinositide kinases and phosphatases
2009 StandoutNobel
Early cardiac hypertrophy in mice with impaired calmodulin regulation of cardiac muscle Ca2+ release channel
2007 StandoutNobel
Erk5 Activation Elicits a Vasoprotective Endothelial Phenotype via Induction of Krüppel-like Factor 4 (KLF4)
2010
PECAM-1 directed re-targeting of exogenous mRNA providing two orders of magnitude enhancement of vascular delivery and expression in lungs independent of apolipoprotein E-mediated uptake
2018 StandoutNobel
The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in Health and Disease
2017 Standout
Molecular distinction between physiological and pathological cardiac hypertrophy: Experimental findings and therapeutic strategies
2010
Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy
2005 Standout
Barrier protective effects of rutin in LPS-induced inflammation in vitro and in vivo
2012
Anti-inflammatory effects of rutin on HMGB1-induced inflammatory responses in vitro and in vivo
2013
Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance
2006 Standout
Mitochondria: More Than Just a Powerhouse
2006 Standout
Defining the regulation of KLF4 expression and its downstream transcriptional targets in vascular endothelial cells
2009
Role of mitogen-activated protein kinase kinase kinases in signal integration
2007
JAK/STAT, Raf/MEK/ERK, PI3K/Akt and BCR-ABL in cell cycle progression and leukemogenesis
2004
Flow-Mediated Signaling Modulates Endothelial Cell Phenotype
2006
Effect of oxymatrine, the active component from Radix Sophorae flavescentis (Kushen), on ventricular remodeling in spontaneously hypertensive rats
2012
cGMP-Dependent Protein Kinases and cGMP Phosphodiesterases in Nitric Oxide and cGMP Action
2010 Standout
Graves' Ophthalmopathy
2010 Standout
High-mobility group box 1 restores cardiac function after myocardial infarction in transgenic mice
2008
Involvement of early growth response gene 1 in the modulation of microsomal prostaglandin E synthase 1 by epigallocatechin gallate in A549 human pulmonary epithelial cells
2006
MAP kinase signalling cascades and transcriptional regulation
2012
Ras, PI3-kinase and mTOR signaling in cardiac hypertrophy
2004
Inhibitors of cyclic nucleotide phosphodiesterase 3 and 5 as therapeutic agents in heart failure
2006
Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach
2018 Standout
Minocycline Protects Cardiac Myocytes Against Simulated Ischemia–Reperfusion Injury by Inhibiting Poly(ADP-ribose) Polymerase-1
2010
Physiology and Pathophysiology of Purinergic Neurotransmission
2007 Standout
Regulation of Androgen Receptor Signaling by PTEN (Phosphatase and Tensin Homolog Deleted on Chromosome 10) Tumor Suppressor through Distinct Mechanisms in Prostate Cancer Cells
2004
Hesperidin, hesperidin methyl chalone and phellopterin from Poncirus trifoliata (Rutaceae) differentially regulate the expression of adhesion molecules in tumor necrosis factor-α-stimulated human umbilical vein endothelial cells
2008
Portrait of PTEN: Messages from mutant mice
2008 StandoutNobel
WNK1 Activates ERK5 by an MEKK2/3-dependent Mechanism
2004
The tumor microenvironment and its role in promoting tumor growth
2008 Standout
Reactive oxygen species in cancer
2010 Standout
Mitogen-Activated Protein (MAP) Kinase/MAP Kinase Phosphatase Regulation: Roles in Cell Growth, Death, and Cancer
2008
Anti-inflammatory Effects of Baicalin, Baicalein, and Wogonin In Vitro and In Vivo
2014
Crosstalk in NF-κB signaling pathways
2011 Standout
The inflammatory response in myocardial injury, repair, and remodelling
2014 Standout
Plant-derived immunomodulators: an insight on their preclinical evaluation and clinical trials
2015 Standout
Tumor Necrosis Factor-α Inhibits Endothelial Nitric-oxide Synthase Gene Promoter Activity in Bovine Aortic Endothelial Cells
2004
Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases
2019 Standout
Regulation of cardiac hypertrophy by intracellular signalling pathways
2006 Standout
NOX4-dependent Hydrogen peroxide promotes shear stress-induced SHP2 sulfenylation and eNOS activation
2015
The Pathobiology of Vascular Dementia
2013 Standout
The MAP Kinase Signaling Cascades: A System of Hundreds of Components Regulates a Diverse Array of Physiological Functions
2010
Regulation of endothelial barrier function during flow-induced conversion to an arterial phenotype
2007 StandoutNobel
Fluvastatin inhibits AGE-induced cell proliferation and migration via an ERK5-dependent Nrf2 pathway in vascular smooth muscle cells
2017
Anti-inflammatory actions of PPAR ligands: new insights on cellular and molecular mechanisms
2007
Reactive oxygen species, cellular redox systems, and apoptosis
2010 Standout
Mitochondrial ROS – radical detoxification, mediated by protein kinase D
2006
Exploring the full spectrum of macrophage activation
2008 Standout
The therapeutic potential of carbon monoxide
2010 Standout
Naringenin has anti‐inflammatory properties in macrophage and ex vivo human whole‐blood models
2008
cGMP-Hydrolytic Activity and Its Inhibition by Sildenafil in Normal and Failing Human and Mouse Myocardium
2009
The MAP kinase ERK5 binds to and phosphorylates p90 RSK
2006
MAP kinase and pain
2008 Standout
The role of IL-6 and STAT3 in inflammation and cancer
2005 Standout
Microvascular Dysfunction and Cognitive Impairment
2016
Endothelial protective genes induced by statin are mimicked by ERK5 activation as triggered by a drug combination of FTI-277 and GGTI-298
2015
Redox Control of Endothelial Function and Dysfunction: Molecular Mechanisms and Therapeutic Opportunities
2008
MAPK signalling: ERK5 versus ERK1/2
2006
Protecting against vascular disease in brain
2011
Intracellular signaling mechanisms of sex hormones in acute myocardial inflammation and injury
2005
Reciprocal Relationships Between Insulin Resistance and Endothelial Dysfunction
2006 Standout
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
The MAPK pathway across different malignancies: A new perspective
2014 Standout
EFFECTS OF DEEP-SEA WATER ON CARDIAC ABNORMALITY IN HIGH-CHOLESTEROL DIETARY MICE
2011
Cardiac hypertrophy and sudden death in mice with a genetically clamped renin transgene
2004 StandoutNobel
High Mobility Group Box 1 Promotes Angiogenesis from Bone Marrow-derived Endothelial Progenitor Cells after Myocardial Infarction
2015
The coordinated increased expression of biliverdin reductase and heme oxygenase‐2 promotes cardiomyocyte survival: a reductase‐based peptide counters β‐adrenergic receptor ligand‐mediated cardiac dysfunction
2010
Minocycline: far beyond an antibiotic
2013 Standout
Role of Ca 2+ /Calmodulin-Stimulated Cyclic Nucleotide Phosphodiesterase 1 in Mediating Cardiomyocyte Hypertrophy
2009
Neurotrophin-regulated signalling pathways
2006 Standout
Activation of Extracellular Signal-Regulated Kinase by Stretch-Induced Injury in Astrocytes Involves Extracellular ATP and P2 Purinergic Receptors
2003
The Biological Basis for Cardiac Repair After Myocardial Infarction
2016 Standout
Compartmentation of Cyclic Nucleotide Signaling in the Heart
2006
Increased Endothelial Mitogen-Activated Protein Kinase Phosphatase-1 Expression Suppresses Proinflammatory Activation at Sites That Are Resistant to Atherosclerosis
2008
Novel Mechanisms of Endothelial Mechanotransduction
2014
Involvement of Extracellular Signal-Regulated Kinases 1/2 in Cardiac Hypertrophy and Cell Death
2002
Atheroprotective Signaling Mechanisms Activated by Steady Laminar Flow in Endothelial Cells
2008
Endothelial Cell Dysfunction and the Pathobiology of Atherosclerosis
2016 Standout
Identification of Activators of ERK5 Transcriptional Activity by High-Throughput Screening and the Role of Endothelial ERK5 in Vasoprotective Effects Induced by Statins and Antimalarial Agents
2014
On the pivotal role of PPARa in adaptation of the heart to hypoxia and why fat in the diet increases hypoxic injury
2016 StandoutNobel
Overview of PDEs and Their Regulation
2007
Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives
2011 Standout
Reactive Oxygen Species–Mediated Mitochondria-to-Nucleus Signaling: A Key to Aging and Radical-Caused Diseases
2006
Techniques for Analysis of Plant Phenolic Compounds
2013 Standout
Works of Wenyi Che being referenced
ERK1/2 Associates with the c-Met-binding Domain of Growth Factor Receptor-bound Protein 2 (Grb2)-associated Binder-1 (Gab1)
2004
Suppression of Estrogen Receptor-mediated Transcription and Cell Growth by Interaction with TR2 Orphan Receptor
2002
Activation of big MAP kinase 1 (BMK1/ERK5) inhibits cardiac injury after myocardial ischemia and reperfusion
2004
ERK5 Activation Inhibits Inflammatory Responses via Peroxisome Proliferator-activated Receptor δ (PPARδ) Stimulation
2006
Mitochondrial Dok-4 Recruits Src Kinase and Regulates NF-κB Activation in Endothelial Cells
2005
Differential Role of MEK5α and MEK5β in BMK1/ERK5 Activation
2004
Bcr in Vascular Smooth Muscle Cells
2001
Insulin-Like Growth Factor-1 Enhances Inflammatory Responses in Endothelial Cells
2002
Inhibition of Tumor Necrosis Factor-α–Induced SHP-2 Phosphatase Activity by Shear Stress
2003
A positive feedback loop of phosphodiesterase 3 (PDE3) and inducible cAMP early repressor (ICER) leads to cardiomyocyte apoptosis
2005
Src and Multiple MAP Kinase Activation in Cardiac Hypertrophy and Congestive Heart Failure Under Chronic Pressure-overload: Comparison with Acute Mechanical Stretch
2001
Bcr Kinase Activation by Angiotensin II Inhibits Peroxisome Proliferator-Activated Receptor γ Transcriptional Activity in Vascular Smooth Muscle Cells
2008
The Hinge-Helix 1 Region of Peroxisome Proliferator-Activated Receptor γ1 (PPARγ1) Mediates Interaction with Extracellular Signal-Regulated Kinase 5 and PPARγ1 Transcriptional Activation: Involvement in Flow-Induced PPARγ Activation in Endothelial Cells
2004