Citation Impact
Citing Papers
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
2009 Standout
Aggregation of embryonic stem cells induces Nanog repression and primitive endoderm differentiation
2004 StandoutNobel
Stem Cell–Derived Culture Models of Hepatitis E Virus Infection
2018 StandoutNobel
Ferroptosis is governed by differential regulation of transcription in liver cancer
2019
Ferroptosis: molecular mechanisms and health implications
2020 Standout
Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs
2016 Standout
Pan-Genotype Hepatitis E Virus Replication in Stem Cell–Derived Hepatocellular Systems
2017 StandoutNobel
Nuclear Hormone Receptor NHR-49 Controls Fat Consumption and Fatty Acid Composition in C. elegans
2005
Mechanisms, regulation and functions of the unfolded protein response
2020 Standout
ω-6 Polyunsaturated fatty acids extend life span through the activation of autophagy
2013 StandoutNobel
Loss of Hepatocyte-Nuclear-Factor-4α Affects Colonic Ion Transport and Causes Chronic Inflammation Resembling Inflammatory Bowel Disease in Mice
2009
Activation of p21/ gene expression and inhibition of cell proliferation by overexpression of hepatocyte nuclear factor-4α
2004
The transcription factor cyclic AMP–responsive element–binding protein H regulates triglyceride metabolism
2011
CpG islands and the regulation of transcription
2011 Standout
MicroRNAs Regulate Human Hepatocyte Nuclear Factor 4α, Modulating the Expression of Metabolic Enzymes and Cell Cycle
2009
Ulcerative Colitis
2011 Standout
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Vascularized and functional human liver from an iPSC-derived organ bud transplant
2013 StandoutNature
Direct Lineage Conversion of Terminally Differentiated Hepatocytes to Functional Neurons
2011 StandoutNobel
Hypomorphic Mutation in the Site-1 Protease Mbtps1 Endows Resistance to Persistent Viral Infection in a Cell-Specific Manner
2011 StandoutNobel
Network motifs: theory and experimental approaches
2007 Standout
Transcriptional regulation of the human hepatic lipase (LIPC) gene promoter
2006
Efficient Generation of Functional Hepatocytes From Human Embryonic Stem Cells and Induced Pluripotent Stem Cells by HNF4α Transduction
2011
Liver-Enriched Transcription Factor CREBH Interacts With Peroxisome Proliferator-Activated Receptor α to Regulate Metabolic Hormone FGF21
2014
The unfolded protein response: controlling cell fate decisions under ER stress and beyond
2012 Standout
Transcriptional Networks and Signaling Pathways that Govern Vertebrate Intestinal Development
2010
Hepatic insulin signalling is dispensable for suppression of glucose output by insulin in vivo
2015
The signalling from endoplasmic reticulum-resident bZIP transcription factors involved in diverse cellular physiology
2011
Organoid Models and Applications in Biomedical Research
2015 Standout
Molecular Mechanism of Liver Development and Regeneration
2007
Hepatocyte Polarity
2012
Behavior of tight-junction, adherens-junction and cell polarity proteins during HNF-4α-induced epithelial polarization
2005
Mapping and analysis of chromatin state dynamics in nine human cell types
2011 StandoutNature
An HNF4α-miRNA Inflammatory Feedback Circuit Regulates Hepatocellular Oncogenesis
2011
Embryonic development of the liver†
2005
Zinc Supplementation Reverses Alcohol-Induced Steatosis in Mice Through Reactivating Hepatocyte Nuclear Factor-4α and Peroxisome Proliferator-Activated Receptor-α†
2009
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
Binding of pRB to the PHD Protein RBP2 Promotes Cellular Differentiation
2005 StandoutNobel
Sequence features that drive human promoter function and tissue specificity
2010
Two to Tango: Regulation of Mammalian Iron Metabolism
2010 Standout
Suppression of the hepcidin‐encoding gene Hamp permits iron overload in mice lacking both hemojuvelin and matriptase‐2/TMPRSS6
2009 StandoutNobel
p21 in cancer: intricate networks and multiple activities
2009 Standout
Genetic polymorphism of hepatocyte nuclear factor‐4α influences human cytochrome P450 2D6 activity†
2008
INVOLVEMENT OF HEPATOCYTE NUCLEAR FACTOR 4α IN THE DIFFERENT EXPRESSION LEVEL BETWEEN CYP2C9 AND CYP2C19 IN THE HUMAN LIVER
2006
Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload
2005
Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
2010 Standout
Human occludin is a hepatitis C virus entry factor required for infection of mouse cells
2009 StandoutNatureNobel
Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?
2007 Standout
Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells
2005 Standout
Intestinal epithelial cells: regulators of barrier function and immune homeostasis
2014 Standout
Evidence for epithelial-mesenchymal transitions in adult liver cells
2006
Liver development update: new embryo models, cell lineage control, and morphogenesis
2004
Genetics and pathogenesis of inflammatory bowel disease
2011 StandoutNature
Operational definition of intrinsically unstructured protein sequences based on susceptibility to the 20S proteasome
2007
Disruption of Paneth and goblet cell homeostasis and increased endoplasmic reticulum stress in Agr2−/− mice
2009 StandoutNobel
Alcoholic Liver Disease: Pathogenesis and New Therapeutic Targets
2011 Standout
Transmembrane proteins of tight junctions
2007
Endoplasmic reticulum-tethered transcription factor cAMP responsive element-binding protein, hepatocyte specific, regulates hepatic lipogenesis, fatty acid oxidation, and lipolysis upon metabolic stress in mice
2011
Targeting the Achilles heel of the hepatitis B virus: a review of current treatments against covalently closed circular DNA
2015 StandoutNobel
Revisiting STAT3 signalling in cancer: new and unexpected biological functions
2014 Standout
Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation
2013 Standout
Developmental Regulation of Hepatitis B Virus Biosynthesis by Hepatocyte Nuclear Factor 4α
2009
Snail controls differentiation of hepatocytes by repressing HNF4α expression
2006
TGF-β-induced epithelial to mesenchymal transition
2009 Standout
Genetics of ulcerative colitis
2010
Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver
2008 Standout
Stem cell-derived polarized hepatocytes
2020 StandoutNobel
Organogenesis and Development of the Liver
2010
Humanized mice efficiently engrafted with fetal hepatoblasts and syngeneic immune cells develop human monocytes and NK cells
2016 StandoutNobel
The transcription factor grainyhead-like 2 regulates the molecular composition of the epithelial apical junctional complex
2010
Three-dimensional culture and cAMP signaling promote the maturation of human pluripotent stem cell-derived hepatocytes
2013
Identification, Molecular Cloning, and Analysis of Full-Length Hepatitis C Virus Transmitted/Founder Genotypes 1, 3, and 4
2015 StandoutNobel
Nuclear Receptor Hepatocyte Nuclear Factor 4α1 Competes with Oncoprotein c-Myc for Control of the p21/WAF1 Promoter
2007
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Quantitative Proteomics Identifies Host Factors Modulated during Acute Hepatitis E Virus Infection in the Swine Model
2014
Identification and differentiation of hepatic stem cells during liver development
2006
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
2014 StandoutNobel
In situ expansion of engineered human liver tissue in a mouse model of chronic liver disease
2017 StandoutNobel
Control of Pancreas and Liver Gene Expression by HNF Transcription Factors
2004 Science
Organogenesis in a dish: Modeling development and disease using organoid technologies
2014 StandoutScience
Concise Review: Mesenchymal Stem/Multipotent Stromal Cells: The State of Transdifferentiation and Modes of Tissue Repair—Current Views
2007 Standout
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Inflammatory Bowel Disease
2010 Standout
Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells
2012 StandoutNobel
GATA4 is essential for formation of the proepicardium and regulates cardiogenesis
2004
Unique antiviral mechanism discovered in anti-hepatitis B virus research with a natural product analogue
2007
Hepatocyte Polarity
2013
HNF4A is essential for specification of hepatic progenitors from human pluripotent stem cells
2011
Claudins and the Modulation of Tight Junction Permeability
2013 Standout
Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response
2009 StandoutNobel
Regulation of hepatic autophagy by stress‐sensing transcription factor CREBH
2019
MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands
2010 StandoutNobel
Hepatocyte Nuclear Factor 4α, a Key Factor for Homeostasis, Cell Architecture, and Barrier Function of the Adult Intestinal Epithelium
2009
Works of Wendy Garrison being referenced
Hepatocyte nuclear factor 4α is implicated in endoplasmic reticulum stress–induced acute phase response by regulating expression of cyclic adenosine monophosphate responsive element binding protein H†
2008
Hepatocyte nuclear factor 4α controls the development of a hepatic epithelium and liver morphogenesis
2003
Generation of single-copy transgenic mouse embryos directly from ES cells by tetraploid embryo complementation
2001
Hepatocyte Nuclear Factor 4α Is Essential for Embryonic Development of the Mouse Colon
2006
Hnf4: A Central Regulator of Hepatocyte Differentiation and Function
2003