Citation Impact
Citing Papers
A myocardium tropic adeno-associated virus (AAV) evolved by DNA shuffling and in vivo selection
2009
Oligonucleotide conjugated multi-functional adeno-associated viruses
2018
Screening Libraries to Discover Molecular Design Principles for the Targeted Delivery of mRNA with One-Component Ionizable Amphiphilic Janus Dendrimers Derived from Plant Phenolic Acids
2023 StandoutNobel
Next generation of adeno-associated virus 2 vectors: Point mutations in tyrosines lead to high-efficiency transduction at lower doses
2008
Engineering adeno-associated viruses for clinical gene therapy
2014
Superior In vivo Transduction of Human Hepatocytes Using Engineered AAV3 Capsid
2016 StandoutNobel
In Vivo Selection Yields AAV-B1 Capsid for Central Nervous System and Muscle Gene Therapy
2016
AAV Capsid Structure and Cell Interactions
2011
Non-uniform refinement: adaptive regularization improves single-particle cryo-EM reconstruction
2020 Standout
Off-target-free gene delivery by affinity-purified receptor-targeted viral vectors
2015
Innovation by homologous recombination
2013 StandoutNobel
Quantification of adeno-associated virus particles and empty capsids by optical density measurement
2003
Tropism-modified AAV Vectors Overcome Barriers to Successful Cutaneous Therapy
2014
Adeno-associated virus (AAV) capsid genes isolated from rat and mouse liver genomic DNA define two new AAV species distantly related to AAV-5
2006
Development of next generation adeno-associated viral vectors capable of selective tropism and efficient gene delivery
2015
Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects
2020 Standout
Applications of CRISPR-Cas Enzymes in Cancer Therapeutics and Detection
2018 StandoutNobel
Altering AAV tropism with mosaic viral capsids
2005
Ocular Drug Delivery
2010 Standout
In situ immune response and mechanisms of cell damage in central nervous system of fatal cases microcephaly by Zika virus
2018 Standout
A Cas9 Ribonucleoprotein Platform for Functional Genetic Studies of HIV-Host Interactions in Primary Human T Cells
2016 StandoutNobel
Evolution of a designed protein assembly encapsulating its own RNA genome
2017 StandoutNatureNobel
Random peptide libraries displayed on adeno-associated virus to select for targeted gene therapy vectors
2003
Two distinct regions in Staphylococcus aureus GatCAB guarantee accurate tRNA recognition
2009
Non-viral vectors for gene-based therapy
2014 Standout
PEGylation as a strategy for improving nanoparticle-based drug and gene delivery
2015 Standout
Reengineering a receptor footprint of adeno-associated virus enables selective and systemic gene transfer to muscle
2009
Genome Engineering Using Adeno-associated Virus: Basic and Clinical Research Applications
2015
Germline viral “fossils” guide in silico reconstruction of a mid-Cenozoic era marsupial adeno-associated virus
2016
AAV Hybrid Serotypes: Improved Vectors for Gene Delivery
2005
DNA Shuffling of Adeno-associated Virus Yields Functionally Diverse Viral Progeny
2008
Vector Design Tour de Force: Integrating Combinatorial and Rational Approaches to Derive Novel Adeno-associated Virus Variants
2014
Applications of contact predictions to structural biology
2017 StandoutNobel
Directed evolution of adeno-associated virus yields enhanced gene delivery vectors
2006
Virus entry: molecular mechanisms and biomedical applications
2004
Adeno-associated virus (AAV) vectors in cancer gene therapy
2016
The potential of adeno-associated viral vectors for gene delivery to muscle tissue
2014
Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues
2008 Standout
The AAV Vector Toolkit: Poised at the Clinical Crossroads
2012
In Silico Reconstruction of the Viral Evolutionary Lineage Yields a Potent Gene Therapy Vector
2015
Progress and problems with the use of viral vectors for gene therapy
2003 Standout
Adeno-associated virus vector as a platform for gene therapy delivery
2019 Standout
Use of covariance analysis for the prediction of structural domain boundaries from multiple protein sequence alignments
2002
Phase 1 Gene Therapy for Duchenne Muscular Dystrophy Using a Translational Optimized AAV Vector
2011
ResLog plots as an empirical metric of the quality of cryo-EM reconstructions
2014
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
Directed Evolution of Adeno-associated Virus for Enhanced Gene Delivery and Gene Targeting in Human Pluripotent Stem Cells
2011
AAV Vectors Vaccines Against Infectious Diseases
2014
Optimization of the Capsid of Recombinant Adeno-Associated Virus 2 (AAV2) Vectors: The Final Threshold?
2013
AAV-ID: A Rapid and Robust Assay for Batch-to-Batch Consistency Evaluation of AAV Preparations
2017
Sub-2 Å Ewald curvature corrected structure of an AAV2 capsid variant
2018
PEG conjugation moderately protects adeno‐associated viral vectors against antibody neutralization
2005
Optogenetics in Neural Systems
2011 Standout
Gene transfer to the lung: Lessons learned from more than 2 decades of CF gene therapy
2008
Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity
2017
Development of Virus-Like Particle Technology from Small Highly Symmetric to Large Complex Virus-Like Particle Structures
2013 Standout
Adeno-Associated Virus at 50: A Golden Anniversary of Discovery, Research, and Gene Therapy Success—A Personal Perspective
2015
The Unexpected Importance of the Primary Structure of the Hydrophobic Part of One-Component Ionizable Amphiphilic Janus Dendrimers in Targeted mRNA Delivery Activity
2022 StandoutNobel
Physiological Implications of Hydrogen Sulfide: A Whiff Exploration That Blossomed
2012 Standout
Adeno-Associated Virus Type 2 VP2 Capsid Protein Is Nonessential and Can Tolerate Large Peptide Insertions at Its N Terminus
2004
One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA
2021 StandoutNobel
Efficiency of Protease-Activatable Virus Nanonodes Tuned Through Incorporation of Wild-Type Capsid Subunits
2014
Cryo-electron Microscopy Reconstruction and Stability Studies of the Wild Type and the R432A Variant of Adeno-associated Virus Type 2 Reveal that Capsid Structural Stability Is a Major Factor in Genome Packaging
2016
Capsid Antibodies to Different Adeno-Associated Virus Serotypes Bind Common Regions
2013
Ionizable lipid nanoparticles deliver mRNA to pancreatic β cells via macrophage-mediated gene transfer
2023 StandoutNobel
A parvovirus isolated from royal python (Python regius) is a member of the genus Dependovirus
2004
Intratumoral activation of the necroptotic pathway components RIPK1 and RIPK3 potentiates antitumor immunity
2019 StandoutNobel
Molecular Characterization of Adeno-Associated Viruses Infecting Children
2005
Robust and accurate prediction of residue–residue interactions across protein interfaces using evolutionary information
2014 StandoutNobel
Adeno-Associated Virus Structural Biology as a Tool in Vector Development
2013
Overcoming Preexisting Humoral Immunity to AAV Using Capsid Decoys
2013
Virus-mediated gene transfer to induce therapeutic angiogenesis: where do we stand?
2007
The Assembly-Activating Protein Promotes Capsid Assembly of Different Adeno-Associated Virus Serotypes
2011
Immune responses to AAV vectors: overcoming barriers to successful gene therapy
2013
SCHEMA Computational Design of Virus Capsid Chimeras: Calibrating How Genome Packaging, Protection, and Transduction Correlate with Calculated Structural Disruption
2013
A Precise Chemical Strategy To Alter the Receptor Specificity of the Adeno‐Associated Virus
2016
New tools for automated high-resolution cryo-EM structure determination in RELION-3
2018 Standout
Site-Specific PEGylated Adeno-Associated Viruses with Increased Serum Stability and Reduced Immunogenicity
2017
Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery
2017 StandoutNobel
Adeno-Associated Virus Type 2 Capsids with Externalized VP1/VP2 Trafficking Domains Are Generated prior to Passage through the Cytoplasm and Are Maintained until Uncoating Occurs in the Nucleus
2006
Comparative Analysis of Adeno-Associated Virus Capsid Stability and Dynamics
2013
Adeno-associated viruses undergo substantial evolution in primates during natural infections
2003
Nontoxic nanopore electroporation for effective intracellular delivery of biological macromolecules
2019 StandoutNobel
Works of Weishu Bu being referenced
Prediction of protein (domain) structural classes based on amino‐acid index
1999
Insights into tRNA-Dependent Amidotransferase Evolution and Catalysis from the Structure of the Aquifex aeolicus Enzyme
2009
The atomic structure of adeno-associated virus (AAV-2), a vector for human gene therapy
2002