Citation Impact
Citing Papers
Improvement of comparative model accuracy by free-energy optimization along principal components of natural structural variation
2004 StandoutNobel
Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBβ)
2001 StandoutScience
Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex
2005 StandoutScience
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
Keeping G Proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and Gßγ
2003 StandoutScienceNobel
High Frequency of Mutations of the PIK3CA Gene in Human Cancers
2004 StandoutScience
New connections in the regulation of PEPCK gene expression by insulin
1996
Agonist-stimulated synthesis of phosphatidylinositol(3,4,5)-trisphosphate
1993
Akt/Protein Kinase B Is Regulated by Autophosphorylation at the Hypothetical PDK-2 Site
2000
Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects.
1995
Intracellular signalling: PDK1 – a kinase at the hub of things
1999
PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2
1999
Activation of Atypical Protein Kinase C ζ by Caspase Processing and Degradation by the Ubiquitin-Proteasome System
2000 StandoutNobel
The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
1997 StandoutNatureNobel
Protection from obesity-induced insulin resistance in mice lacking TNF-α function
1997 StandoutNature
Oncogenic kinase signalling
2001 StandoutNature
The Severe Acute Respiratory Syndrome
2003
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
High resolution crystal structure of the human PDK1 catalytic domain defines the regulatory phosphopeptide docking site
2002
Mechanism of Protein Kinase B Activation by Insulin/Insulin-Like Growth Factor-1 Revealed by Specific Inhibitors of Phosphoinositide 3-Kinase—Significance for Diabetes and Cancer
1999
The catalytic subunit of cAMP-dependent protein kinase: prototype for an extended network of communication
1999
The Role of Phosphoinositide 3-Kinase Lipid Products in Cell Function
1999
A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans
1996 StandoutNatureNobel
PAR‐6 regulates aPKC activity in a novel way and mediates cell‐cell contact‐induced formation of the epithelial junctional complex
2001
DNA-dependent protein kinase catalytic subunit: A relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product
1995
A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans
1999 StandoutNobel
Association of Atypical Protein Kinase C Isotypes with the Docker Protein FRS2 in Fibroblast Growth Factor Signaling
1999
Phosphatidylinositol-3-OH kinase direct target of Ras
1994 StandoutNature
Thrombin signalling and protease-activated receptors
2000 StandoutNature
Enhanced Mass Spectrometric Mapping of the Human GalNAc-type O-Glycoproteome with SimpleCells
2013
Rho GTPases in cell biology
2002 StandoutNature
Tor, a Phosphatidylinositol Kinase Homologue, Controls Autophagy in Yeast
1998 StandoutNobel
Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway
1999 Standout
Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kγ
2000 StandoutNatureNobel
Increased levels of phosphatidylinositol 3-kinase activity in colorectal tumors
1998
When is a lipid kinase not a lipid kinase? When it is a protein kinase
1995
Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells
2023 StandoutNobel
Ribosomal S6 Kinase Signaling and the Control of Translation
1999
Tumor necrosis factor-alpha- and hyperglycemia-induced insulin resistance. Evidence for different mechanisms and different effects on insulin signaling.
1996
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
2001 StandoutNature
Insulin Regulation of Phosphoenolpyruvate Carboxykinase Gene Expression Does Not Require Activation of the Ras/Mitogen-activated Protein Kinase Signaling Pathway
1996
Phosphatidylinositol 3‐kinase
1994
Insulin signalling and the regulation of glucose and lipid metabolism
2001 StandoutNature
The challenge of emerging and re-emerging infectious diseases
2004 StandoutNature
An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior
2005 StandoutNobel
The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells
2000
Cellular responses to DNA damage: cell-cycle checkpoints, apoptosis and the roles of p53 and ATM
1995
Reactive oxygen species have a causal role in multiple forms of insulin resistance
2006 StandoutNature
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
The DNA damage response: putting checkpoints in perspective
2000 StandoutNature
Identification and characterization of a new oncogene derived from the regulatory subunit of phosphoinositide 3-kinase
1998
A mammalian protein targeted by G1-arresting rapamycin–receptor complex
1994 StandoutNature
A human homolog of the C. elegans polarity determinant Par-6 links Rac and Cdc42 to PKCζ signaling and cell transformation
2000
Unique Structural and Functional Properties of the ATP-binding Domain of Atypical Protein Kinase C-ι
2000
Integrins
2002 Standout
Comparison of ultrafiltration units for proteomic and N-glycoproteomic analysis by the filter-aided sample preparation method
2010
Signalling through phosphoinositide 3-kinases: the lipids take centre stage
1999
ATR is a caffeine-sensitive, DNA-activated protein kinase with a substrate specificity distinct from DNA-PK
1999
RNA–protein analysis using a conditional CRISPR nuclease
2013 StandoutNobel
Protein Phosphatase 2A Negatively Regulates Insulin's Metabolic Signaling Pathway by Inhibiting Akt (Protein Kinase B) Activity in 3T3-L1 Adipocytes
2004
Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm
2003
Regulation of C. elegans Life-Span by Insulinlike Signaling in the Nervous System
2000 StandoutScienceNobel
Rap1 Is a Potent Activation Signal for Leukocyte Function-Associated Antigen 1 Distinct from Protein Kinase C and Phosphatidylinositol-3-OH Kinase
2000
Protein Analysis by Shotgun/Bottom-up Proteomics
2013
Cancer Cell Cycles
1996 StandoutScience
Chitosan—A versatile semi-synthetic polymer in biomedical applications
2011 Standout
CHITIN AND CHITOSAN FOR VERSATILE APPLICATIONS
2002
Phosphorylation and activation of cAMP-dependent protein kinase by phosphoinositide-dependent protein kinase
1998
Prion protein (PrP) synthetic peptides induce cellular PrP to acquire properties of the scrapie isoform.
1995 StandoutNobel
Reversal of Obesity- and Diet-Induced Insulin Resistance with Salicylates or Targeted Disruption of Ikkβ
2001 StandoutScience
A Self-Assembled Multivalent Pseudopolyrotaxane for Binding Galectin-1
2004 StandoutNobel
Uses for JNK: the Many and Varied Substrates of the c-Jun N-Terminal Kinases
2006
Integrins and Signal Transduction Pathways: the Road Taken
1995 StandoutScience
Activation of the ATM Kinase by Ionizing Radiation and Phosphorylation of p53
1998 StandoutScience
Activation of platelet phosphatidylinositide 3-kinase requires the small GTP-binding protein Rho.
1993
Aging, life span, and senescence
1998 StandoutNobel
Engineering Orthogonal Polypeptide GalNAc-Transferase and UDP-Sugar Pairs
2019 StandoutNobel
Phosphoinositide 3-kinase is activated by phosphopeptides that bind to the SH2 domains of the 85-kDa subunit
1993
TOR1 and TOR2 are structurally and functionally similar but not identical phosphatidylinositol kinase homologues in yeast.
1994
Aquaglyceroporin AQP9: Solute permeation and metabolic control of expression in liver
2003 StandoutNobel
daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans
1997 StandoutScienceNobel
Biodegradable Long-Circulating Polymeric Nanospheres
1994 StandoutScience
Dual roles of ATM in the cellular response to radiation and in cell growth control.
1996 Nobel
The structure of the inter-SH2 domain of class IA phosphoinositide 3-kinase determined by site-directed spin labeling EPR and homology modeling
2003
Polymers for biodegradable medical devices. 1. The potential of polyesters as controlled macromolecular release systems
1986
Enhanced Phosphorylation of p53 by ATM in Response to DNA Damage
1998 StandoutScience
Function of PI3Kγ in Thymocyte Development, T Cell Activation, and Neutrophil Migration
2000 StandoutScienceNobel
Pathophysiology and Pharmacological Treatment of Insulin Resistance*
2000
Autophagy as a Regulated Pathway of Cellular Degradation
2000 StandoutScience
Preferential binding of ATR protein to UV-damaged DNA
2002 StandoutNobel
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Chemical Glycoproteomics
2016 StandoutNobel
The PI3K–PDK1 connection: more than just a road to PKB
2000
The Atr and Atm protein kinases associate with different sites along meiotically pairing chromosomes.
1996
Works of Weimin Hou being referenced
c-Jun N-Terminal Kinases Mediate Reactivation of Akt and Cardiomyocyte Survival After Hypoxic Injury In Vitro and In Vivo
2005
Regulation of protein kinase C ζ by PI 3-kinase and PDK-1
1998
Attenuation of SARS coronavirus by a short hairpin RNA expression plasmid targeting RNA-dependent RNA polymerase
2004
New ammunition for the proteomic reactor: strong anion exchange beads and multiple enzymes enhance protein identification and sequence coverage
2010
PDK1 mediates growth factor-induced Ral-GEF activation by a kinase-independent mechanism
2002
The Proteomic Reactor: A Microfluidic Device for Processing Minute Amounts of Protein Prior to Mass Spectrometry Analysis
2006
Controlled drug release by ultrasound irradiation.
1985
Sustained release of indomethacin from chitosan granules.
1985
A Tightly Associated Serine/Threonine Protein Kinase Regulates Phosphoinositide 3-Kinase Activity
1993
Sustained-release and intragastric-floating granules of indomethacin using chitosan in rabbits.
1988