Wei Yan

Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation

Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble

(+)- and (−)-liriodenol, a pair of novel enantiomeric lignans from Liriodendron hybrid

Recent advances in research on lignans and neolignans

Engineering enzymes for noncanonical amino acid synthesis

A Panel of TrpB Biocatalysts Derived from Tryptophan Synthase through the Transfer of Mutations that Mimic Allosteric Activation

Improved Synthesis of 4-Cyanotryptophan and Other Tryptophan Analogues in Aqueous Solvent Using Variants of TrpB from Thermotoga maritima

The First One-Pot Synthesis of l-7-Iodotryptophan from 7-Iodoindole and Serine, and an Improved Synthesis of Other l-7-Halotryptophans

Unlocking Reactivity of TrpB: A General Biocatalytic Platform for Synthesis of Tryptophan Analogues

Marine natural products

Synthesis of β-Branched Tryptophan Analogues Using an Engineered Subunit of Tryptophan Synthase

Bioactive Chaetoglobosins from the Mangrove Endophytic Fungus Penicillium chrysogenum

A Panel of TrpB Biocatalysts Derived from Tryptophan Synthase through the Transfer of Mutations that Mimic Allosteric Activation

Cephalosol: An Antimicrobial Metabolite with an Unprecedented Skeleton from Endophytic Cephalosporium acremonium IFB‐E007

Precursor-directed fungal generation of novel halogenated chaetoglobosins with more preferable immunosuppressive action