Citation Impact
Citing Papers
Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro
2003 StandoutNobel
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
( R )-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible
2013 StandoutScienceNobel
Ferroptosis regulation by the NGLY1/NFE2L1 pathway
2022 StandoutNobel
De novo design of picomolar SARS-CoV-2 miniprotein inhibitors
2020 StandoutScienceNobel
Centromeres and Kinetochores
2003
Activation of nuclear factor κB in inflammatory bowel disease
1998
Chemical characterization and source apportionment of PM 2.5 in Beijing: seasonal perspective
2013
Hierarchical design of pseudosymmetric protein nanocages
2024 StandoutNatureNobel
The rise of intelligent matter
2021 Nature
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
Hydrogen peroxide sensing, signaling and regulation of transcription factors
2014
Aneuploidy: Instigator and Inhibitor of Tumorigenesis
2007
Cancer Chemoprevention and Nutri-Epigenetics: State of the Art and Future Challenges
2012
Human Zwint-1 Specifies Localization of Zeste White 10 to Kinetochores and Is Essential for Mitotic Checkpoint Signaling
2004
The spindle checkpoint: structural insights into dynamic signalling
2002
Diabetic retinopathy
2010 Standout
Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
2012 StandoutNature
Getting in and out of mitosis with Polo-like kinase-1
2005
Cell death by mitotic catastrophe: a molecular definition
2004
Long-term Treatment with Suberythropoietic Epo is Vaso- and Neuroprotective in Experimental Diabetic Retinopathy
2011
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Cell cycle proteins as promising targets in cancer therapy
2017 Standout
Cell-cycle checkpoints and cancer
2004 StandoutNature
Protein-tyrosine Phosphatase Inhibitors Block Tumor Necrosis Factor-dependent Activation of the Nuclear Transcription Factor NF-kB
1995
Identification of a MAD2-binding protein, CMT2, and its role in mitosis
2002
Mad2 Overexpression Promotes Aneuploidy and Tumorigenesis in Mice
2006
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
2014 StandoutNature
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
2005 StandoutNature
Identification of the transforming EML4–ALK fusion gene in non-small-cell lung cancer
2007 StandoutNature
The contribution of outdoor air pollution sources to premature mortality on a global scale
2015 StandoutNature
A Quantitative Systems Approach Reveals Dynamic Control of tRNA Modifications during Cellular Stress
2010
Plk4 haploinsufficiency causes mitotic infidelity and carcinogenesis
2005
DNA damage checkpoints in mammals
2005
ON01910, a non-ATP-competitive small molecule inhibitor of Plk1, is a potent anticancer agent
2005
Reduced Life- and Healthspan in Mice Carrying a Mono-Allelic BubR1 MVA Mutation
2012
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
2001 StandoutNature
Constitutional aneuploidy and cancer predisposition caused by biallelic mutations in BUB1B
2004
The multilayered complexity of ceRNA crosstalk and competition
2014 StandoutNature
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
2011 StandoutNatureNobel
A DNA damage checkpoint response in telomere-initiated senescence
2003 StandoutNature
Stuck in Division or Passing through
2004
Aneuploidy: a matter of bad connections
2005
Immune Signaling by RIG-I-like Receptors
2011
A census of mitotic cancer genes: new insights into tumor cell biology and cancer therapy
2006
CDK1 stabilizes HIF-1α via direct phosphorylation of Ser668 to promote tumor growth
2013
Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands
2015
Deficiency of SPARC suppresses intestinal tumorigenesis in APC Min/+ mice
2007 StandoutNobel
Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan
2012
Non-ATP competitive protein kinase inhibitors as anti-tumor therapeutics
2009
Poly(ADP-ribose): novel functions for an old molecule
2006 Standout
Cell cycle kinases in cancer
2007
Bub1 Maintains Centromeric Cohesion by Activation of the Spindle Checkpoint
2007
Polo-like kinases: positive regulators of cell division from start to finish
1998
γH2AX and cancer
2008
The anaphase-promoting complex: it's not just for mitosis any more
2002
Sak Serine-Threonine Kinase Acts as an Effector of Tec Tyrosine Kinase
2001
The Cdt1 protein is required to license DNA for replication in fission yeast
2000 StandoutNatureNobel
Aneuploidy Acts Both Oncogenically and as a Tumor Suppressor
2006
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
Mad2-Independent Inhibition of APCCdc20 by the Mitotic Checkpoint Protein BubR1
2001
Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex
2004 StandoutNatureNobel
Cell cycle, CDKs and cancer: a changing paradigm
2009 Standout
MicroRNA expression profiles classify human cancers
2005 StandoutNatureNobel
Novel Targets Against Retinal Angiogenesis in Diabetic Retinopathy
2012
Mitochondria as multifaceted regulators of cell death
2019 Standout
The role of senescent cells in ageing
2014 StandoutNature
Epigenetic modifications and human disease
2010 Standout
Ferroptosis: mechanisms, biology and role in disease
2021 Standout
The functions and regulation of the PTEN tumour suppressor
2012 Standout
The Hallmarks of Aging
2013 Standout
CDC5 and CKII Control Adaptation to the Yeast DNA Damage Checkpoint
1997 StandoutNobel
Activating and Silencing the Mitotic Checkpoint through CENP-E-Dependent Activation/Inactivation of BubR1
2003
On the road to cancer: aneuploidy and the mitotic checkpoint
2005
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
Targeting polo-like kinase 1 for cancer therapy
2006
Automatically Fixing Errors in Glycoprotein Structures with Rosetta
2018
Mitotic Checkpoint Slippage in Humans Occurs via Cyclin B Destruction in the Presence of an Active Checkpoint
2006
The Molecular Basis for Phosphodependent Substrate Targeting and Regulation of Plks by the Polo-Box Domain
2003
The cancer genome
2009 StandoutNature
The spindle-assembly checkpoint in space and time
2007 Standout
Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease
2007 StandoutNobel
Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint
2004
Polo-Like Kinase 1 Is Essential for Early Embryonic Development and Tumor Suppression
2008
BI 6727, A Polo-like Kinase Inhibitor with Improved Pharmacokinetic Profile and Broad Antitumor Activity
2009
Intervention With an Erythropoietin-Derived Peptide Protects Against Neuroglial and Vascular Degeneration During Diabetic Retinopathy
2011
Angiopoietin-like 4 is a potent angiogenic factor and a novel therapeutic target for patients with proliferative diabetic retinopathy
2015 StandoutNobel
β-Arrestin inhibits NF-κB activity by means of its interaction with the NF-κB inhibitor IκBα
2004 StandoutNobel
JAK2 activation by growth hormone and other cytokines
2015
Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kappa B.
1996 Standout
Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2
2001
Reconstitution of a human ATR-mediated checkpoint response to damaged DNA
2007 StandoutNobel
DNA-Containing Exosomes Derived from Cancer Cells Treated with Topotecan Activate a STING-Dependent Pathway and Reinforce Antitumor Immunity
2017
Acute myeloid leukemia carrying cytoplasmic/mutated nucleophosmin (NPMc+ AML): biologic and clinical features
2006
Mice with the CHEK2 *1100delC SNP are predisposed to cancer with a strong gender bias
2009
Attachment and tension in the spindle assembly checkpoint
2002
Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression
2014 StandoutNobel
Tumor necrosis factor and lymphotoxin. Qualitative and quantitative differences in the mediation of early and late cellular response.
1994
Plk Phosphorylation Regulates the Microtubule-Stabilizing Protein TCTP
2002
Iterative in Situ Click Chemistry Assembles a Branched Capture Agent and Allosteric Inhibitor for Akt1
2011 StandoutNobel
Insights into Cytokine–Receptor Interactions from Cytokine Engineering
2014
Checkpoint Protein BubR1 Acts Synergistically with Mad2 to Inhibit Anaphase-promoting Complex
2002
Apoptosis Associated with Deregulated E2F Activity Is Dependent on E2F1 and Atm/Nbs1/Chk2
2004
Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome
2004 StandoutNobel
New Insights into the Troubles of Aneuploidy
2012
Small molecule probes to quantify the functional fraction of a specific protein in a cell with minimal folding equilibrium shifts
2014 StandoutNobel
Identification of Genes Periodically Expressed in the Human Cell Cycle and Their Expression in Tumors
2002
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Receptor-mediated dimerization of JAK2 FERM domains is required for JAK2 activation
2018
Aneuploidy-Cancer Predisposition Syndromes: A New Link between the Mitotic Spindle Checkpoint and Cancer
2004
Spindle Checkpoint Protein Bub1 Is Required for Kinetochore Localization of Mad1, Mad2, Bub3, and Cenp-E, Independently of Its Kinase Activity
2001
Toward Maintaining the Genome: DNA Damage and Replication Checkpoints
2002
Polo kinase: the choreographer of the mitotic stage?
1996
Activity-Based Protein Profiling: From Enzyme Chemistry to Proteomic Chemistry
2008
ChatGPT Chemistry Assistant for Text Mining and the Prediction of MOF Synthesis
2023 StandoutNobel
Fission Yeast Mad3p Is Required for Mad2p To Inhibit the Anaphase-Promoting Complex and Localizes to Kinetochores in a Bub1p-, Bub3p-, and Mph1p-Dependent Manner
2002
INITIATION OF DNA REPLICATION IN EUKARYOTIC CELLS
1997
Receptor dimerization dynamics as a regulatory valve for plasticity of type I interferon signaling
2015
Works of Wei Dai being referenced
Polo-like Kinase 3 Functions as a Tumor Suppressor and Is a Negative Regulator of Hypoxia-Inducible Factor-1α under Hypoxic Conditions
2008
Polo-like kinases and the microtubule organization center: targets for cancer therapies.
2003
Incomplete cytokinesis and induction of apoptosis by overexpression of the mammalian polo-like kinase, Plk3.
2000
Polo-like Kinases Inhibited by Wortmannin
2006
Phosphorylation of H3S10 Blocks the Access of H3K9 by Specific Antibodies and Histone Methyltransferase
2008
Regulation of PTEN Stability and Activity by Plk3
2010
Plk3 Functions as an Essential Component of the Hypoxia Regulatory Pathway by Direct Phosphorylation of HIF-1α
2010
Cytometry of ATM activation and histone H2AX phosphorylation to estimate extent of DNA damage induced by exogenous agents
2007
Identifying anthropogenic and natural influences on extreme pollution of respirable suspended particulates in Beijing using backward trajectory analysis
2007
Caenorhabditis ElegansContains Structural Homologs of Humanprkandplk
1999
Regulation of cell cycle checkpoints by polo-like kinases
2005
Enhanced Gel Mobility Shift Assay for DNA-Binding Factors
1993
prk, a Cytokine-inducible Human Protein Serine/Threonine Kinase Whose Expression Appears to be Down-regulated in Lung Carcinomas
1996
Polo-like kinase 3 is Golgi localized and involved in regulating Golgi fragmentation during the cell cycle
2003
p55CDC/hCDC20 is associated with BUBR1 and may be a downstream target of the spindle checkpoint kinase
2000
Programmable artificial phototactic microswimmer
2016
Reactive Oxygen Species-induced Phosphorylation of p53 on Serine 20 Is Mediated in Part by Polo-like Kinase-3
2001
Rig-I−/− mice develop colitis associated with downregulation of Gαi2
2007
Plk3 Functionally Links DNA Damage to Cell Cycle Arrest and Apoptosis at Least in Part via the p53 Pathway
2001
Human Prk Is a Conserved Protein Serine/Threonine Kinase Involved in Regulating M Phase Functions
1997
The physical association and phosphorylation of Cdc25C protein phosphatase by Prk
1999
A genome-wide screen in Saccharomyces cerevisiae reveals pathways affected by arsenic toxicity
2009
B23/Nucleophosmin Serine 4 Phosphorylation Mediates Mitotic Functions of Polo-like Kinase 1
2004
Activity-based probes for functional interrogation of retaining β-glucuronidases
2017
BubR1 is involved in regulation of DNA damage responses
2006
Polo-like kinases and centrosome regulation
2002
ATM activation and histone H2AX phosphorylation as indicators of DNA damage by DNA topoisomerase I inhibitor topotecan and during apoptosis
2006
Effects of hydroxyurea and aphidicolin on phosphorylation of ataxia telangiectasia mutated on Ser 1981 and histone H2AX on Ser 139 in relation to cell cycle phase and induction of apoptosis
2006
Mechanism of Activation of Protein Kinase JAK2 by the Growth Hormone Receptor
2014 Science
Phenylhexyl isothiocyanate inhibits histone deacetylases and remodels chromatins to induce growth arrest in human leukemia cells
2006
Colonic tumorigenesis in BubR1 +/– Apc Min /+ compound mutant mice is linked to premature separation of sister chromatids and enhanced genomic instability
2005
Intravitreal Injection of Erythropoietin Protects both Retinal Vascular and Neuronal Cells in Early Diabetes
2008
Cell Cycle Arrest and Apoptosis Induced by Human Polo-Like Kinase 3 Is Mediated through Perturbation of Microtubule Integrity
2002
Slippage of Mitotic Arrest and Enhanced Tumor Development in Mice with BubR1 Haploinsufficiency
2004
Ferroptosis as a target for protection against cardiomyopathy
2019 Standout
Human Bub1: a putative spindle checkpoint kinase closely linked to cell proliferation.
1998
Epigenetic mechanism of growth inhibition induced by phenylhexyl isothiocyanate in prostate cancer cells.
2006