W.E. van Spil

Osteoarthritis, obesity and weight loss: evidence, hypotheses and horizons – a scoping review

Synovitis in osteoarthritis: current understanding with therapeutic implications

Inflammatory mediators in osteoarthritis: A critical review of the state-of-the-art, current prospects, and future challenges

3D osteoarthritic changes in TMJ condylar morphology correlates with specific systemic and local biomarkers of disease

Biologic basis of osteoarthritis

Metabolic triggered inflammation in osteoarthritis

In vivo imaging of MMP-13 activity in the murine destabilised medial meniscus surgical model of osteoarthritis

Etiology of osteoarthritis: genetics and synovial joint development

Inflammatory ultrasound features show independent associations with progression of structural damage after over 2 years of follow-up in patients with hand osteoarthritis

Senescent cells: an emerging target for diseases of ageing

Osteoarthritis

Identifying effector molecules, cells, and cytokines of innate immunity in OA

Cellular senescence in ageing: from mechanisms to therapeutic opportunities

Osteoarthritis as an inflammatory disease (osteoarthritis is not osteoarthrosis!)

The role of atherosclerosis in osteoarthritis

The Effects of a Calcium-Rich Pre-Exercise Meal on Biomarkers of Calcium Homeostasis in Competitive Female Cyclists: A Randomised Crossover Trial

Low-grade inflammation as a key mediator of the pathogenesis of osteoarthritis

Applications of machine learning in drug discovery and development

An update on the pathophysiology of osteoarthritis

Osteoarthritis

Osteoarthritis year 2012 in review: biomarkers

Biomarkers as drug development tools: discovery, validation, qualification and use

Phenotypes of osteoarthritis: current state and future implications.

Physiology of sweat gland function: The roles of sweating and sweat composition in human health

Diagnosis and Treatment of Hip and Knee Osteoarthritis

Knee osteoarthritis has doubled in prevalence since the mid-20th century

Current Understanding of Pathogenesis and Treatment of TMJ Osteoarthritis

Osteoarthritis: an update with relevance for clinical practice

Knee joint distraction compared with total knee arthroplasty

Systemic biochemical markers of joint metabolism and inflammation in relation to radiographic parameters and pain of the knee: data from CHECK, a cohort of early-osteoarthritis subjects

Associations of CTX-II with biochemical markers of bone turnover raise questions on its tissue origin: data from CHECK, a cohort study of early osteoarthritis

Serum and urinary biochemical markers for knee and hip-osteoarthritis: a systematic review applying the consensus BIPED criteria

A sex-specific association between incident radiographic osteoarthritis of hip or knee and incident peripheral arterial calcifications: 8-year prospective data from Cohort Hip and Cohort Knee (CHECK)

Six weeks of continuous joint distraction appears sufficient for clinical benefit and cartilaginous tissue repair in the treatment of knee osteoarthritis

An explorative study comparing levels of soluble mediators in control and osteoarthritic synovial fluid

Clusters within a wide spectrum of biochemical markers for osteoarthritis: data from CHECK, a large cohort of individuals with very early symptomatic osteoarthritis

Trajectories of femorotibial cartilage thickness among persons with or at risk of knee osteoarthritis: development of a prediction model to identify progressors

Serum adipokines in osteoarthritis; comparison with controls and relationship with local parameters of synovial inflammation and cartilage damage

Efficacy of bisphosphonates in specific knee osteoarthritis subpopulations: protocol for an OA Trial Bank systematic review and individual patient data meta-analysis

Osteoarthritis Year in Review 2016: biomarkers (biochemical markers)

Molecular taxonomy of osteoarthritis for patient stratification, disease management and drug development: biochemical markers associated with emerging clinical phenotypes and molecular endotypes