Citation Impact
Citing Papers
Epigenetic Silencing of MicroRNA-34b/c and B-Cell Translocation Gene 4 Is Associated with CpG Island Methylation in Colorectal Cancer
2008
ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation
2009 StandoutScience
Circulating microRNA profiles in human patients with acetaminophen hepatotoxicity or ischemic hepatitis
2014 StandoutNobel
Aberrant Silencing of Cancer-Related Genes by CpG Hypermethylation Occurs Independently of Their Spatial Organization in the Nucleus
2010
Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble
2018 StandoutNobel
DNA Methylation and Complete Transcriptional Silencing of Cancer Genes Persist after Depletion of EZH2
2007
Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
2009 StandoutScience
RNA-Guided Human Genome Engineering via Cas9
2013 StandoutScience
Genomic and Epigenomic Integration Identifies a Prognostic Signature in Colon Cancer
2011
Targeted Methylation of Two Tumor Suppressor Genes Is Sufficient to Transform Mesenchymal Stem Cells into Cancer Stem/Initiating Cells
2011
UCHIME improves sensitivity and speed of chimera detection
2011 Standout
( R )-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible
2013 StandoutScienceNobel
Methylation of Polycomb Target Genes in Intestinal Cancer Is Mediated by Inflammation
2008
Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA
2011 StandoutScience
Cancer and Altered Metabolism: Potential Importance of Hypoxia-Inducible Factor and 2-Oxoglutarate-Dependent Dioxygenases
2011 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma
2008
Concepts of epigenetics in prostate cancer development
2008
PAINS: Relevance to Tool Compound Discovery and Fragment-Based Screening
2013
Genome-scale DNA methylation maps of pluripotent and differentiated cells
2008 StandoutNature
Signals and Combinatorial Functions of Histone Modifications
2011
Histone acetylation and chromatin signature in stem cell identity and cancer
2007
The Ink4/Arf locus is a barrier for iPS cell reprogramming
2009 Nature
Augmenting Antitumor Immune Responses with Epigenetic Modifying Agents
2015
Functions of DNA methylation: islands, start sites, gene bodies and beyond
2012 Standout
Epigenetic regulation of theINK4b-ARF-INK4alocus
2010
The Highly Cooperative Folding of Small Naturally Occurring Proteins Is Likely the Result of Natural Selection
2007 StandoutNobel
A DNA hypermethylation module for the stem/progenitor cell signature of cancer
2012
CpG islands and the regulation of transcription
2011 Standout
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Protein functional landscapes, dynamics, allostery: a tortuous path towards a universal theoretical framework
2010
Metabolic Regulation of Epigenetics
2012
Convergence of Mutation and Epigenetic Alterations Identifies Common Genes in Cancer That Predict for Poor Prognosis
2008
Developmental programming of CpG island methylation profiles in the human genome
2009
Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina–associated domains
2011
Hallmarks of aging: An expanding universe
2023 Standout
Stability and flexibility of epigenetic gene regulation in mammalian development
2007 Nature
Cancer Epigenetics: From Mechanism to Therapy
2012 Standout
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
2011 StandoutNature
The multilayered complexity of ceRNA crosstalk and competition
2014 StandoutNature
CpG island hypermethylation-associated silencing of non-coding RNAs transcribed from ultraconserved regions in human cancer
2010
Cancer stem-like cells contribute to cisplatin resistance and progression in bladder cancer
2012
Epigenetics in Cancer
2008 Standout
Mitochondria: In Sickness and in Health
2012 Standout
Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes
2015 StandoutNobel
Critical issues of clinical human embryonic stem cell therapy for brain repair
2008
The Histone Chaperone Spt6 Is Required for Activation-induced Cytidine Deaminase Target Determination through H3K4me3 Regulation
2012 StandoutNobel
Fibroblast growth factor signalling: from development to cancer
2010 Standout
Deep Sequencing the MicroRNA Transcriptome in Colorectal Cancer
2013
Integrated Analyses Identify a Master MicroRNA Regulatory Network for the Mesenchymal Subtype in Serous Ovarian Cancer
2013
Regulation and function of DNA methylation in plants and animals
2011
Integrated genomic characterization of endometrial carcinoma
2013 StandoutNature
Butyrate Promotes Induced Pluripotent Stem Cell Generation
2010
Lineage-Specific Polycomb Targets and De Novo DNA Methylation Define Restriction and Potential of Neuronal Progenitors
2008
Immunity, Inflammation, and Cancer
2010 Standout
TET enzymes, TDG and the dynamics of DNA demethylation
2013 StandoutNature
From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites
2016 Standout
Promoter CpG Methylation Contributes to ES Cell Gene Regulation in Parallel with Oct4/Nanog, PcG Complex, and Histone H3 K4/K27 Trimethylation
2008
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
2017 Standout
EMT: 2016
2016 Standout
Genomic patterns of DNA methylation: targets and function of an epigenetic mark
2007
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
2018 StandoutNobel
Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation
2008
Epigenetic modifications as therapeutic targets
2010
A Fresh Look at iPS Cells
2009 StandoutNobel
Stem Cell Chromatin Patterns: An Instructive Mechanism for DNA Hypermethylation?
2007
Removal of deaminated cytosines and detection of in vivo methylation in ancient DNA
2009 StandoutNobel
MS-qFRET: A quantum dot-based method for analysis of DNA methylation
2009
Genetic and epigenetic stability of human pluripotent stem cells
2012
Aberrant Epigenetic Landscape in Cancer: How Cellular Identity Goes Awry
2010
The Hallmarks of Aging
2013 Standout
Rapamycin and other longevity‐promoting compounds enhance the generation of mouse induced pluripotent stem cells
2011
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
2010 StandoutNature
Widespread and tissue specific age-related DNA methylation changes in mice
2010
A decade of exploring the cancer epigenome — biological and translational implications
2011 Standout
Genome-scale analysis of aberrant DNA methylation in colorectal cancer
2011
IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
2012 Nature
Human DNA methylomes at base resolution show widespread epigenomic differences
2009 StandoutNature
Orphan CpG Islands Identify Numerous Conserved Promoters in the Mammalian Genome
2010
A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping
2014 Standout
Alternative transcription and alternative splicing in cancer
2012
Flexibility and Design: Conformational Heterogeneity along the Evolutionary Trajectory of a Redesigned Ubiquitin
2017
Linking DNA methylation and histone modification: patterns and paradigms
2009 Standout
The Polycomb complex PRC2 and its mark in life
2011 StandoutNature
PcG Proteins, DNA Methylation, and Gene Repression by Chromatin Looping
2008
A Novel CpG Island Set Identifies Tissue-Specific Methylation at Developmental Gene Loci
2008
Relationship between Gene Body DNA Methylation and Intragenic H3K9me3 and H3K36me3 Chromatin Marks
2011
The presence of RNA polymerase II, active or stalled, predicts epigenetic fate of promoter CpG islands
2009
Nuclear reprogramming to a pluripotent state by three approaches
2010 StandoutNatureNobel
Consolidation of the cancer genome into domains of repressive chromatin by long-range epigenetic silencing (LRES) reduces transcriptional plasticity
2010
Reducing the Impact of PCR-Mediated Recombination in Molecular Evolution and Environmental Studies Using a New-Generation High-Fidelity DNA Polymerase
2009
Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line
2008
Reconstructing the DNA Methylation Maps of the Neandertal and the Denisovan
2014 StandoutScienceNobel
Funnel sculpting for in silico assembly of secondary structure elements of proteins
2003 StandoutNobel
Electrostatic origin of the mechanochemical rotary mechanism and the catalytic dwell of F1-ATPase
2011 StandoutNobel
Recent Stem Cell Advances: Induced Pluripotent Stem Cells for Disease Modeling and Stem Cell–Based Regeneration
2010 StandoutNobel
How does a protein fold?
1994 Nature
Spermidine in health and disease
2018 StandoutScience
Specific promoter methylation identifies different subgroups of MLL-rearranged infant acute lymphoblastic leukemia, influences clinical outcome, and provides therapeutic options
2009
Metabolic reprogramming and cancer progression
2020 StandoutScience
Site-specific gene correction of a point mutation in human iPS cells derived from an adult patient with sickle cell disease
2011
Cancer Genome Landscapes
2013 StandoutScience
Epithelial Plasticity: A Common Theme in Embryonic and Cancer Cells
2013 StandoutScience
Chemistry: Chemical con artists foil drug discovery
2014 StandoutNature
Cancer Epigenetics: Modifications, Screening, and Therapy
2007
Works of Wayne Yu being referenced
Promoter Methylation of Genes in and around the Candidate Lung Cancer Susceptibility Locus 6q23-25
2008
Pre-processing Agilent microarray data
2007
Novel candidate colorectal cancer biomarkers identified by methylation microarray-based scanning
2011
Comparing the DNA Hypermethylome with Gene Mutations in Human Colorectal Cancer
2007
Expression of cancer/testis antigens in prostate cancer is associated with disease progression
2010
Androgen-induced programs for prostate epithelial growth and invasion arise in embryogenesis and are reactivated in cancer
2008
A stem cell–like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing
2007
Exploring the Energy Landscape of Antibody−Antigen Complexes: Protein Dynamics, Flexibility, and Molecular Recognition
2008
Butyrate Greatly Enhances Derivation of Human Induced Pluripotent Stem Cells by Promoting Epigenetic Remodeling and the Expression of Pluripotency-Associated Genes
2010
Detection of High Levels of Recombination Generated During PCR Amplification of RNA Templates
2006
Adaptive Mutations Alter Antibody Structure and Dynamics during Affinity Maturation
2015
Differentiation of a Highly Tumorigenic Basal Cell Compartment in Urothelial Carcinoma
2009
Protein dynamics in minimyoglobin: is the central core of myoglobin the conformational domain?
1993