Citation Impact
Citing Papers
Rhizobium induces DNA damage in Caenorhabditis elegans intestinal cells
2019 StandoutNobel
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Functional diversity of helper T lymphocytes
1996 StandoutNature
Cloning of a new cytokine that induces IFN-γ production by T cells
1995 StandoutNature
A Toll-like receptor recognizes bacterial DNA
2000 StandoutNature
Predictive motifs derived from cytosine methyltransferases
1989 StandoutNobel
The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells
2006 Standout
mRNA Is an Endogenous Ligand for Toll-like Receptor 3
2004 StandoutNobel
The role of IL-12 in the induction of organ-specific autoimmune diseases
1995
Intestinal homeostasis and its breakdown in inflammatory bowel disease
2011 StandoutNature
Age-associated changes in DNA methylation and mRNA level of the c-myc gene in spleen and liver of mice
1989
Unravelling the pathogenesis of inflammatory bowel disease
2007 StandoutNature
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
2003 StandoutNature
Pathogenesis and therapy of psoriasis
2007 StandoutNature
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
1992 Standout
A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment
2000 Standout
Novel IL-12 family members shed light on the orchestration of Th1 responses
2003
The inhibitory cytokine IL-35 contributes to regulatory T-cell function
2007 StandoutNature
IL-21 initiates an alternative pathway to induce proinflammatory TH17 cells
2007 StandoutNature
Cytokine production in the central nervous system of Lewis rats with experimental autoimmune encephalomyelitis: dynamics of mRNA expression for interleukin-10, interleukin-12, cytolysin, tumor necrosis factor α and tumor necrosis factor β
1995
T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions
1998 StandoutNature
Immune-Neuro-Endocrine Interactions: Facts and Hypotheses
1996
EBNA1-specific CD4+ T cells in healthy carriers of Epstein-Barr virus are primarily Th1 in function
2001 StandoutNobel
Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cells
2003
A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
1997 StandoutNature
Cytokines as Endogenous Pyrogens
1999
GATA-3 Significantly Downregulates IFN-γ Production from Developing Th1 Cells in Addition to Inducing IL-4 and IL-5 Levels
1999
The fission yeast gene pmt1+encodes a DNA methyltransferase homologue
1995 StandoutNobel
Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression
1998 StandoutNature
The Gene Ontology Annotation (GOA) Project: Implementation of GO in SWISS-PROT, TrEMBL, and InterPro
2003
Cell-mediated cytotoxicity
1993 StandoutNobel
Interleukin‐12 is required for interferon‐γ production and lethality in lipopolysaccharide‐induced shock in mice
1995
Analysis of tumor necrosis factor promoter responses to ultraviolet light.
1994 StandoutNobel
Lymphotoxin ?, a novel member of the TNF family that forms a heteromeric complex with lymphotoxin on the cell surface
1993
Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells
1988
DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development
1999 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene
1996 StandoutNatureNobel
Cell type-specific activation of mitogen-activated protein kinases by CpG-DNA controls interleukin-12 release from antigen-presenting cells
1999
Dendritic cells and the control of immunity
1998 StandoutNatureNobel
Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
2010 StandoutNature
Acute-Phase Proteins and Other Systemic Responses to Inflammation
1999 Standout
Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
1996 StandoutNatureNobel
Interleukin‐12 is produced by dendritic cells and mediates T helper 1 development as well as interferon‐γ production by T helper 1 cells
1996 StandoutNobel
IL-12-Deficient Mice Are Defective in IFNγ Production and Type 1 Cytokine Responses
1996
Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology
2010 Nature
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Natural killer cell stimulatory factor (NKSF) or interleukin-12 is a key regulator of immune response and inflammation
1992
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
An Interleukin (IL)-10/IL-12 Immunoregulatory Circuit Controls Susceptibility to Autoimmune Disease
1998
Recombinant interleukin 12 cures mice infected with Leishmania major.
1993 Standout
A Novel Concept for the Combinatorial Synthesis of Peptide Nucleic Acids.
1998
Mammalian DNA ligases. Catalytic domain and size of DNA ligase I.
1990 StandoutNobel
Response of human natural killer (NK) cells to NK cell stimulatory factor (NKSF): cytolytic activity and proliferation of NK cells are differentially regulated by NKSF.
1992
STATs and Gene Regulation
1997 StandoutScience
Interactions Between the Microbiota and the Immune System
2012 StandoutScience
CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation.
1995 StandoutNobel
[7] Synthetic adaptors for cloning DNA
1979
Dendritic Cells Induce Peripheral T Cell Unresponsiveness under Steady State Conditions in Vivo
2001 StandoutNobel
Interleukin-12 p40 gene (IL12B) 3′-untranslated region polymorphism is associated with susceptibility to atopic dermatitis and psoriasis vulgaris
2002
Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cells
2003
Endogenous interleukin 12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology.
1994
Recent Developments in Isocyanide Based Multicomponent Reactions in Applied Chemistry
2005 Standout
High level IL-12 production by murine dendritic cells: upregulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10.
1996
Interleukin 12 is required for the T-lymphocyte-independent induction of interferon gamma by an intracellular parasite and induces resistance in T-cell-deficient hosts.
1993
Human Dendritic Cells Activate Resting Natural Killer (NK) Cells and Are Recognized via the NKp30 Receptor by Activated NK Cells
2002 StandoutNobel
Reversibility of T helper 1 and 2 populations is lost after long-term stimulation.
1996
Multiple Control Elements Mediate Activation of the Murine and Human Interleukin 12 p40 Promoters: Evidence of Functional Synergy between C/EBP and Rel Proteins
1997
Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells.
1993 Standout
Development of T H 1 CD4 + T Cells Through IL-12 Produced by Listeria -Induced Macrophages
1993 StandoutScience
Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4.
1995
Purification of a factor which provides a costimulatory signal for gamma interferon production
1993
Ubiquitous Transgenic Expression of the IL-23 Subunit p19 Induces Multiorgan Inflammation, Runting, Infertility, and Premature Death
2001
PD-1 deficiency reveals various tissue-specific autoimmunity by H-2band dose-dependent requirement of H-2g7for diabetes in NOD mice
2008 StandoutNobel
B7 and interleukin 12 cooperate for proliferation and interferon gamma production by mouse T helper clones that are unresponsive to B7 costimulation.
1994
The Role of DNA Methylation in Mammalian Epigenetics
2001 StandoutScience
Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells.
1992
IL-23: A Cytokine That Acts on Memory T Cells
2002
Interleukin 12: A key modulator of immune function
1994
The structure of two subgenomic RNAs from human infhienza virus A/PR/8/34
1981 StandoutNobel
Requirement for V α 14 NKT Cells in IL-12-Mediated Rejection of Tumors
1997 Science
Interleukin 12 and tumor necrosis factor alpha are costimulators of interferon gamma production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist.
1993
Antitumor and antimetastatic activity of interleukin 12 against murine tumors.
1993
Effects of DNA methylation on topoisomerase I and II cleavage activities.
1994 StandoutNobel
THE INTERLEUKIN-12/INTERLEUKIN-12-RECEPTOR SYSTEM: Role in Normal and Pathologic Immune Responses
1998
Epstein–Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietin
1997
Unique insertion site of Tn7 in the E. coli chromosome
1982 StandoutNatureNobel
A novel interleukin-12 p40-related protein induced by latent Epstein-Barr virus infection in B lymphocytes
1996
Cutting Edge: Diabetes-Associated Quantitative Trait Locus, Idd4, Is Responsible for the IL-12p40 Overexpression Defect in Nonobese Diabetic (NOD) Mice
2003
Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper 1 and T helper 2 populations.
1995
Contribution of the CXC chemokines IP-10 and Mig to the antitumor effects of IL-12
1998
Recombination and balanced chromosome polymorphism suggested by DNA sequences 5' to the human delta-globin gene.
1983 StandoutNobel
Unraveling Function in the TNF Ligand and Receptor Families
1994 StandoutScienceNobel
Mammalian DNA methyltransferases prefer poly(dI-dC) as substrate.
1986
Works of Warren McComas being referenced
Coexpression of two distinct genes is required to generate secreted bioactive cytotoxic lymphocyte maturation factor.
1991
Chemical synthesis of two deoxyribododecanucleotides for the attachment of restriction termini to an artificial minigene
1977
Oligomer synthesis and DNA/RNA recognition properties of a novel oligonucleotide backbone analog: Glucopyranosyl nucleic amide (GNA)
1997
Cloning and expression of murine IL-12
1992
DNA methylation: sequences flanking C-G pairs modulate the specificity of the human DNA methylase
1985