Citation Impact
Citing Papers
RIP1 suppresses innate immune necrotic as well as apoptotic cell death during mammalian parturition
2014
PUMA amplifies necroptosis signaling by activating cytosolic DNA sensors
2018
Pyroptosis versus necroptosis: similarities, differences, and crosstalk
2018
An outline of necrosome triggers
2016
Revisiting caspases in sepsis
2014
Ferroptosis: past, present and future
2020 Standout
Necroptosis in anti-viral inflammation
2018
RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL
2015
Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death
2013
Cancer therapy in the necroptosis era
2016
Widespread Mitochondrial Depletion via Mitophagy Does Not Compromise Necroptosis
2013
Ferroptosis: molecular mechanisms and health implications
2020 Standout
Necroptosis is preceded by nuclear translocation of the signaling proteins that induce it
2015
Emerging roles of PKM2 in cell metabolism and cancer progression
2012 StandoutNobel
Activity of Uncleaved Caspase-8 Controls Anti-bacterial Immune Defense and TLR-Induced Cytokine Production Independent of Cell Death
2016
Necroinflammation in Kidney Disease
2015
RIP3: a molecular switch for necrosis and inflammation
2013
Ferroptosis: Death by Lipid Peroxidation
2015 Standout
Necroptosis and its role in inflammation
2015 StandoutNature
Inflammation and Cancer: Triggers, Mechanisms, and Consequences
2019 Standout
Hsp90 modulates the stability of MLKL and is required for TNF-induced necroptosis
2016
Dying cells actively regulate adaptive immune responses
2017
RIP3 targets pyruvate dehydrogenase complex to increase aerobic respiration in TNF-induced necroptosis
2018
Chronic inflammation in the etiology of disease across the life span
2019 Standout
Distinct roles of RIP1–RIP3 hetero- and RIP3–RIP3 homo-interaction in mediating necroptosis
2014
Nuclear RIPK3 and MLKL contribute to cytosolic necrosome formation and necroptosis
2018
Targeting Ferroptosis to Iron Out Cancer
2019 Standout
Complex Pathologic Roles of RIPK1 and RIPK3: Moving Beyond Necroptosis
2017
Molecular mechanisms regulating NLRP3 inflammasome activation
2015 Standout
Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis
2013
Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications
2022 Standout
Necroptosis in the Pathophysiology of Disease
2019
Live to die another way: modes of programmed cell death and the signals emanating from dying cells
2015
The Autophagy Machinery Controls Cell Death Switching between Apoptosis and Necroptosis
2016
Inflammaging: a new immune–metabolic viewpoint for age-related diseases
2018 Standout
CaMKII is a RIP3 substrate mediating ischemia- and oxidative stress–induced myocardial necroptosis
2016
Necroptosis and neutrophil-associated disorders
2018
Immunogenic cell death in cancer and infectious disease
2016 Standout
The immune contexture in cancer prognosis and treatment
2017 Standout
Comparing the effects of different cell death programs in tumor progression and immunotherapy
2018
The molecular machinery of regulated cell death
2019 Standout
Macrolides sensitize EGFR-TKI-induced non-apoptotic cell death via blocking autophagy flux in pancreatic cancer cell lines
2015 StandoutNobel
Necroptosis: A new way of dying?
2016
Pyroptosis is driven by non-selective gasdermin-D pore and its morphology is different from MLKL channel-mediated necroptosis
2016
Regulation of RIPK3- and RHIM-dependent Necroptosis by the Proteasome
2016
Necroptosis
2014
Pyroptosis: mechanisms and diseases
2021 Standout
Glutaminolysis and Transferrin Regulate Ferroptosis
2015 Standout
Targeting apoptosis in cancer therapy
2020 Standout
The diverse role of RIP kinases in necroptosis and inflammation
2015
Acute kidney injury
2021 Standout
Induction of necroptotic cell death by viral activation of the RIG-I or STING pathway
2017
RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis
2014
Contribution of RIP3 and MLKL to immunogenic cell death signaling in cancer chemotherapy
2016
Broadening horizons: the role of ferroptosis in cancer
2021 Standout
MLKL Compromises Plasma Membrane Integrity by Binding to Phosphatidylinositol Phosphates
2014
Necroptosis in development and diseases
2018
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
2015 StandoutNature
Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
2016 StandoutNature
Regulation of tumour necrosis factor signalling: live or let die
2015
Activation of apoptosis signalling pathways by reactive oxygen species
2016 Standout
RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway
2014
Regulated necrosis: disease relevance and therapeutic opportunities
2016
Regulated necrosis: the expanding network of non-apoptotic cell death pathways
2014
CYLD Proteolysis Protects Macrophages from TNF-Mediated Auto-necroptosis Induced by LPS and Licensed by Type I IFN
2016
Initiation and execution mechanisms of necroptosis: an overview
2017
Necroptosis in development, inflammation and disease
2016
Silencing of pkm2 increases the efficacy of docetaxel in human lung cancer xenografts in mice
2010
Mixed Lineage Kinase Domain-like Protein MLKL Causes Necrotic Membrane Disruption upon Phosphorylation by RIP3
2014
The many secret lives of adipocytes: implications for diabetes
2018
Targeting autophagy in cancer
2017 Standout
Mitochondria as multifaceted regulators of cell death
2019 Standout
ROS Are Good
2016 Standout
CHIP controls necroptosis through ubiquitylation- and lysosome-dependent degradation of RIPK3
2016
Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death
2016 Standout
<p>Reactive Oxygen Species: Drivers of Physiological and Pathological Processes</p>
2020 Standout
Programmed cell death as a defence against infection
2017
Ferroptosis: mechanisms, biology and role in disease
2021 Standout
Necroptosis: an alternative cell death program defending against cancer
2016
RIPK1 inhibits ZBP1-driven necroptosis during development
2016 Nature
Gasdermins: Effectors of Pyroptosis
2017 Standout
MLKL Requires the Inositol Phosphate Code to Execute Necroptosis
2018
RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome
2017
The Nucleotide Sensor ZBP1 and Kinase RIPK3 Induce the Enzyme IRG1 to Promote an Antiviral Metabolic State in Neurons
2019
Apoptosis and Necroptosis as Host Defense Strategies to Prevent Viral Infection
2017
NF-κB, inflammation, immunity and cancer: coming of age
2018 Standout
Tumor Necrosis Factor Inhibits Spread of Hepatitis C Virus Among Liver Cells, Independent From Interferons
2017 StandoutNobel
Dispensable roles of Gsdmd and Ripk3 in sustaining IL-1β production and chronic inflammation in Th17-mediated autoimmune arthritis
2021 StandoutNobel
Programmed Necrosis and Disease:We interrupt your regular programming to bring you necroinflammation
2018
Plasma membrane changes during programmed cell deaths
2017
Intracellular Nucleic Acid Sensing Triggers Necroptosis through Synergistic Type I IFN and TNF Signaling
2018
Necroptosis: Mechanisms and Relevance to Disease
2016
Programmed necrosis and necroptosis signalling
2014
Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases
2017 Standout
Tumour Necrosis Factor Alpha in Intestinal Homeostasis and Gut Related Diseases
2019
Programmed Necrosis in the Cross Talk of Cell Death and Inflammation
2014
The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis
2016
Pore-forming activity and structural autoinhibition of the gasdermin family
2016 StandoutNature
Kinase Activities of RIPK1 and RIPK3 Can Direct IFN-β Synthesis Induced by Lipopolysaccharide
2017
Necroptosis in health and diseases
2014
Intratumoral activation of the necroptotic pathway components RIPK1 and RIPK3 potentiates antitumor immunity
2019 StandoutNobel
DAMP-sensing receptors in sterile inflammation and inflammatory diseases
2019 Standout
Cytokine Storm
2020 Standout
Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death
2014
Pathophysiology of Type 2 Diabetes Mellitus
2020 Standout
On the Mechanism of Cytoprotection by Ferrostatin-1 and Liproxstatin-1 and the Role of Lipid Peroxidation in Ferroptotic Cell Death
2017 Standout
Die another way – non-apoptotic mechanisms of cell death
2014
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
The deadly landscape of pro‐apoptotic BCL ‐2 proteins in the outer mitochondrial membrane
2015
Ferroptosis as a target for protection against cardiomyopathy
2019 Standout
Cell death: a review of the major forms of apoptosis, necrosis and autophagy
2019 Standout
Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during Yersinia infection
2018
Chaperone-mediated autophagy is involved in the execution of ferroptosis
2019
A new kind of cell suicide: mechanisms and functions of programmed necrosis
2014
The Influence of Probiotics on the Firmicutes/Bacteroidetes Ratio in the Treatment of Obesity and Inflammatory Bowel disease
2020 Standout
Programmed necrosis in inflammation: Toward identification of the effector molecules
2016 Science
Caspase‐8: regulating life and death
2017 Standout
Regulated Cell Death: Signaling and Mechanisms
2014
Works of Wanze Chen being referenced
Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis
2013
The Gβγ-Src signaling pathway regulates TNF-induced necroptosis via control of necrosome translocation
2014
Reversible De-differentiation of Mature White Adipocytes into Preadipocyte-like Precursors during Lactation
2018
Clnk plays a role in TNF-alpha-induced cell death in murine fibrosarcoma cell line L929
2015
RIP1/RIP3 Binding to HSV-1 ICP6 Initiates Necroptosis to Restrict Virus Propagation in Mice
2015
Ppm1b negatively regulates necroptosis through dephosphorylating Rip3
2015
Diverse Sequence Determinants Control Human and Mouse Receptor Interacting Protein 3 (RIP3) and Mixed Lineage Kinase domain-Like (MLKL) Interaction in Necroptotic Signaling
2013
Adenine Nucleotide (ADP/ATP) Translocase 3 Participates in the Tumor Necrosis Factor–induced Apoptosis of MCF-7 Cells
2007