Citation Impact
Citing Papers
Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade
2017 Standout
Increased spatiotemporal resolution reveals highly dynamic dense tubular matrices in the peripheral ER
2016 ScienceNobel
Human Papillomavirus E7 Oncoprotein Overrides the Tumor Suppressor Activity of p21Cip1 in Cervical Carcinogenesis
2009
ER Tubules Mark Sites of Mitochondrial Division
2011 StandoutScience
Disturbed macro-connectivity in schizophrenia linked to oligodendrocyte dysfunction: from structural findings to molecules
2015
Genetic Dissection of the Amyloid Precursor Protein in Developmental Function and Amyloid Pathogenesis
2010 StandoutNobel
Amyloid precursor protein mutation E682K at the alternative β‐secretase cleavage β′‐site increases Aβ generation
2011
Erbin Is Required for Myelination in Regenerated Axons after Injury
2012
Evidence for natural antisense transcript-mediated inhibition of microRNA function
2010
The Alzheimer's β-secretase enzyme BACE1 is required for accurate axon guidance of olfactory sensory neurons and normal glomerulus formation in the olfactory bulb
2011
Head and neck squamous cell carcinoma
2020 Standout
Potent amyloidogenicity and pathogenicity of Aβ43
2011
Ultrastructural Characterization of the Lower Motor System in a Mouse Model of Krabbe Disease
2016 Standout
Synapses and Alzheimer's Disease
2012 StandoutNobel
Alzheimer Precursor Protein Interaction with the Nogo-66 Receptor Reduces Amyloid-β Plaque Deposition
2006
The Neural Cell Adhesion Molecules L1 and CHL1 Are Cleaved by BACE1 Protease in Vivo
2012
Parkinson disease
2017 Standout
Targeting Aβ and tau in Alzheimer's disease, an early interim report
2009
The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics
2011 Standout
Hallmarks of HPV carcinogenesis: The role of E6, E7 and E5 oncoproteins in cellular malignancy
2019
Single-cell-resolution transcriptome map of human, chimpanzee, bonobo, and macaque brains
2020 StandoutNobel
Treatment Strategies Targeting Amyloid -Protein
2012
Intraneuronal amyloid β and reduced brain volume in a novel APP T714I mouse model for Alzheimer's disease
2006
Human papillomavirus oncoproteins: pathways to transformation
2010 Standout
Pharmacological Inhibition of BACE1 Impairs Synaptic Plasticity and Cognitive Functions
2014
Mechanisms of sporadic cerebral small vessel disease: insights from neuroimaging
2013 Standout
A Presenilin-1 Mutation Identified in Familial Alzheimer Disease with Cotton Wool Plaques Causes a Nearly Complete Loss of γ-Secretase Activity
2010
VPS35 in Dopamine Neurons Is Required for Endosome-to-Golgi Retrieval of Lamp2a, a Receptor of Chaperone-Mediated Autophagy That Is Critical for -Synuclein Degradation and Prevention of Pathogenesis of Parkinson's Disease
2015
Guillain-Barré syndrome
2016 Standout
ilastik: interactive machine learning for (bio)image analysis
2019 Standout
The biological properties of E6 and E7 oncoproteins from human papillomaviruses
2009
Trafficking and Proteolytic Processing of APP
2012
Microglial Beclin 1 Regulates Retromer Trafficking and Phagocytosis and Is Impaired in Alzheimer’s Disease
2013
The secretases: enzymes with therapeutic potential in Alzheimer disease
2010
Peripheral nerve proteins as potential autoantigens in acute and chronic inflammatory demyelinating polyneuropathies
2014
Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of β-secretase
2008
Oncogenic activities of human papillomaviruses
2009
Tau in physiology and pathology
2015 Standout
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Immune attack: the role of inflammation in Alzheimer disease
2015 Standout
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Identification of β-Secretase (BACE1) Substrates Using Quantitative Proteomics
2009
Genetics of Brain Fiber Architecture and Intellectual Performance
2009
The human papillomavirus E7 oncoprotein
2008
Modulation of γ- and β-Secretases as Early Prevention Against Alzheimer’s Disease
2017
Long non-coding RNAs: new players in cell differentiation and development
2013 Standout
Caspase Functions in Cell Death and Disease
2013 Standout
Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain
2020 StandoutNobel
Protein aggregation diseases: pathogenicity and therapeutic perspectives
2010
Musical Training as a Framework for Brain Plasticity: Behavior, Function, and Structure
2012 Standout
Flotillin-Dependent Clustering of the Amyloid Precursor Protein Regulates Its Endocytosis and Amyloidogenic Processing in Neurons
2008 StandoutNobel
Alzheimer's disease
2006 Standout
Alzheimer's disease
2016 Standout
Non-coding RNAs in human disease
2011 Standout
Parkinson's disease-linked mutations in VPS35 induce dopaminergic neurodegeneration
2014
GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Aβ42
2007
Animal Models of Alzheimer Disease
2012
Fluorescence nanoscopy in cell biology
2017 StandoutNobel
Unique features of long non-coding RNA biogenesis and function
2015 Standout
Secretome protein enrichment identifies physiological BACE1 protease substrates in neurons
2012
Long noncoding RNAs and human disease
2011 Standout
BACE1-/- mice exhibit seizure activity that does not correlate with sodium channel level or axonal localization
2010
The Amyloid State of Proteins in Human Diseases
2012 Standout
Alzheimer's disease: strategies for disease modification
2010
Reactive Astrocytes: Production, Function, and Therapeutic Potential
2017 Standout
Direct association of the HPV16 E7 oncoprotein with cyclin A/CDK2 and cyclin E/CDK2 complexes
2008
The Impact of Dietary Fiber on Gut Microbiota in Host Health and Disease
2018 Standout
Ferulic Acid Is a Nutraceutical β-Secretase Modulator That Improves Behavioral Impairment and Alzheimer-like Pathology in Transgenic Mice
2013
BACE1 inhibitor drugs in clinical trials for Alzheimer’s disease
2014
Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ
2014 Standout
The Pathobiology of Vascular Dementia
2013 Standout
Evolution and Functions of Long Noncoding RNAs
2009 Standout
The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes
2012 Standout
The Reticulon and Dp1/Yop1p Proteins Form Immobile Oligomers in the Tubular Endoplasmic Reticulum
2008
How culture shaped the human genome: bringing genetics and the human sciences together
2010 Standout
Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
2011 Standout
Intracellular amyloid-β in Alzheimer's disease
2007 Standout
Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio
2010
Negative regulation of myelination: Relevance for development, injury, and demyelinating disease
2008
Single-cell transcriptomic analysis of Alzheimer’s disease
2019 StandoutNature
Long noncoding RNAs: functional surprises from the RNA world
2009 Standout
The amyloid state and its association with protein misfolding diseases
2014 Standout
Gene regulation by long non-coding RNAs and its biological functions
2020 Standout
Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
2011 Standout
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
2010 StandoutNobel
The amyloid hypothesis of Alzheimer's disease at 25 years
2016 Standout
Loss‐of‐function presenilin mutations in Alzheimer disease
2007
Myelin Regeneration: A Recapitulation of Development?
2011
Full length RTN3 regulates turnover of tubular endoplasmic reticulum via selective autophagy
2017
Human Papillomavirus Type 16 E7 Oncoprotein Associates with the Centrosomal Component γ-Tubulin
2007
Qualitative changes in human γ-secretase underlie familial Alzheimer’s disease
2015
Combining an amyloid‐beta (Aβ) cleaving enzyme inhibitor with a γ‐secretase modulator results in an additive reduction of Aβ production
2014
Low‐density lipoprotein receptor‐related protein promotes amyloid precursor protein trafficking to lipid rafts in the endocytic pathway
2007
Hypoxia facilitates Alzheimer's disease pathogenesis by up-regulating BACE1 gene expression
2006
Human Papillomavirus and Cervical Cancer
2003 Standout
Myelination of the Nervous System: Mechanisms and Functions
2014
The mechanism of γ-Secretase dysfunction in familial Alzheimer disease
2012
Unique potential of 4-1BB agonist antibody to promote durable regression of HPV + tumors when combined with an E6/E7 peptide vaccine
2015 StandoutNobel
Amyloid Precursor Protein Processing and Alzheimer's Disease
2011
Long Noncoding RNAs: Past, Present, and Future
2013 Standout
Emerging Therapeutics for Alzheimer's Disease
2014
Attenuating astrocyte activation accelerates plaque pathogenesis in APP/PS1 mice
2012
BACE inhibitors in clinical development for the treatment of Alzheimer’s disease
2018
Proteases and Proteolysis in Alzheimer Disease: A Multifactorial View on the Disease Process
2010
Label‐free quantitative analysis of the membrane proteome of B ace1 protease knock‐out zebrafish brains
2013
Axonal organization defects in the hippocampus of adult conditional BACE1 knockout mice
2018
Chemical Glycoproteomics
2016 StandoutNobel
Global landscape of recent inferred Darwinian selection for Homo sapiens
2005
Works of Wanxia He being referenced
BACE1 Regulates Hippocampal Astrogenesis via the Jagged1-Notch Pathway
2013
Bace1 modulates myelination in the central and peripheral nervous system
2006
Cleavage of Neuregulin-1 by BACE1 or ADAM10 Protein Produces Differential Effects on Myelination
2011
Transgenic mice overexpressing reticulon 3 develop neuritic abnormalities
2007
Processing Amyloid Precursor Protein at the β-Site Requires Proper Orientation to Be Accessed by BACE1
2004
The Membrane Topology of RTN3 and Its Effect on Binding of RTN3 to BACE1
2007
Wild-type Presenilin 1 Protects against Alzheimer Disease Mutation-induced Amyloid Pathology
2006
Reticulon family members modulate BACE1 activity and amyloid-β peptide generation
2004
Impact of RTN3 Deficiency on Expression of BACE1 and Amyloid Deposition
2014
BACE1 deletion in the adult mouse reverses preformed amyloid deposition and improves cognitive functions
2018
VPS35 haploinsufficiency increases Alzheimer’s disease neuropathology
2011
Direct Activation of Cyclin-Dependent Kinase 2 by Human Papillomavirus E7
2003
Genetic deletion of BACE1 in mice affects remyelination of sciatic nerves
2008