Standout Papers

Cloning and functional characterization of mammalian homologues of the COPII component Sec23.... 1996 2026 2006 2016 1.7k
  1. Cloning and functional characterization of mammalian homologues of the COPII component Sec23. (1996)
    J P Paccaud, Walter Reith et al. Molecular Biology of the Cell
  2. Conditional gene targeting in macrophages and granulocytes using LysMcre mice (1999)
    Björn E. Clausen, Christoph Burkhardt et al. Transgenic Research

Citation Impact

Citing Papers

TRP channel activation by reversible covalent modification
2006 StandoutNobel
The macrophage F4/80 receptor is required for the induction of antigen-specific efferent regulatory T cells in peripheral tolerance
2005
DNA capture by a CRISPR-Cas9–guided adenine base editor
2020 StandoutScienceNobel
Origins of Specificity in Protein-DNA Recognition
2010
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
Dendritic Cells Amplify T Cell-Mediated Immune Responses in the Central Nervous System
2006
CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus
2015 StandoutNatureNobel
Four-component protein nanocages designed by programmed symmetry breaking
2024 StandoutNatureNobel
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
2014 StandoutNatureNobel
Differential activation and antagonistic function of HIF-α isoforms in macrophages are essential for NO homeostasis
2010
Hallmarks of Cancer: The Next Generation
2011 Standout
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Inflammation in the Central Nervous System: the Role for Dendritic Cells
2003
IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer
2004 Standout
COPII and secretory cargo capture into transport vesicles
1997 StandoutNobel
A Transgenic Mouse Model of Inducible Macrophage Depletion
2009
Migration of dendritic cells into the brain in a mouse model of prion disease
2005
COPII-Coated Vesicle Formation Reconstituted with Purified Coat Proteins and Chemically Defined Liposomes
1998 StandoutNobel
The ankyrin repeat as molecular architecture for protein recognition
2004
A server and database for dipole moments of proteins
2007
A Primer on Vesicle Budding
1999 StandoutNobel
Regulation of progenitor cell proliferation and granulocyte function by microRNA-223
2008 Nature
Comparative analysis of the efficiency and specificity of myeloid-Cre deleting strains using ROSA-EYFP reporter mice
2014
The microbiota in adaptive immune homeostasis and disease
2016 StandoutNature
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
Coupling of Coat Assembly and Vesicle Budding to Packaging of Putative Cargo Receptors
1999 StandoutNobel
The tumor-promoting actions of TNF-α involve TNFR1 and IL-17 in ovarian cancer in mice and humans
2009
Mammalian Homologues of Yeast Sec31p
2000
Multiple Cargo Binding Sites on the COPII Subunit Sec24p Ensure Capture of Diverse Membrane Proteins into Transport Vesicles
2003 StandoutNobel
Secretory COPII coat component Sec23a is essential for craniofacial chondrocyte maturation
2006
Nomenclature of the ARID family of DNA-binding proteins
2005
Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation
2012 StandoutNatureNobel
Inflammatory processes in the aging mouse brain: Participation of dendritic cells and T-cells
2006
Hypothetical protein KIAA0079 is a mammalian homologue of yeast Sec24p
1999
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
2001 StandoutNature
A novel IL-4 responsive element of the Eα MHC class II promoter that binds to an inducible factor
1995
Analysis of microRNA turnover in mammalian cells following Dicer1 ablation
2011
Promoter polymorphism rs3087456 in the MHC class II transactivator gene is not associated with susceptibility for selected autoimmune diseases in German patient groups
2006
Directed evolution of adenine base editors with increased activity and therapeutic application
2020
Microbial Stimulation Fully Differentiates Monocytes to DC-SIGN/CD209+ Dendritic Cells for Immune T Cell Areas
2010 StandoutNobel
Metazoan MicroRNAs
2018 Standout
IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages
2003
Ubiquitin-dependent regulation of COPII coat size and function
2012 StandoutNatureNobel
COPII Subunit Interactions in the Assembly of the Vesicle Coat
1997
A role of PIEZO1 in iron metabolism in mice and humans
2021 StandoutNobel
TANGO1 Facilitates Cargo Loading at Endoplasmic Reticulum Exit Sites
2009 StandoutNobel
COPII-coated vesicles: flexible enough for large cargo?
2005 StandoutNobel
A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain
2019 StandoutNobel
HIF-1α Is Essential for Myeloid Cell-Mediated Inflammation
2003 Standout
A timeline of tumour-associated macrophage biology
2023
Neither interleukin‐4 receptor α expression on CD4+ T cells, or macrophages and neutrophils is required for protective immunity to Trichinella spiralis
2008
G*Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences
2007 Standout
COPII–cargo interactions direct protein sorting into ER-derived transport vesicles
1998 StandoutNatureNobel
Sar1p N-Terminal Helix Initiates Membrane Curvature and Completes the Fission of a COPII Vesicle
2005 StandoutNobel
Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins
2022
CNS dendritic cells: Critical participants in CNS inflammation?
2006
Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1
2006 StandoutNobel
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene
1996 StandoutNatureNobel
The Primary Immunodeficiencies
1995
Cyclins and cdks in development and cancer: a perspective
2005
The Retinoblastoma Binding Protein RBP2 Is an H3K4 Demethylase
2007 StandoutNobel
Cancer-related inflammation
2008 StandoutNature
Blood-derived dendritic cells in an acute brain injury
2005
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
CD11c/EYFP transgene illuminates a discrete network of dendritic cells within the embryonic, neonatal, adult, and injured mouse brain
2008 StandoutNobel
COPII and selective export from the endoplasmic reticulum
1998
The plant immune system
2006 StandoutNature
Dendritic cells and dendritic-like microglia in focal cortical ischemia of the mouse brain
2002
The Recycling of ERGIC-53 in the Early Secretory Pathway
1997
Hepatitis C Virus RNA Functionally Sequesters miR-122
2015 StandoutNobel
Regulation of a COPII component by cytosolic O‐glycosylation during mitosis
2004
The Antigen-Presenting Activity of Fresh, Adult Parenchymal Microglia and Perivascular Cells from Retina
2004
Metabolic cross-talk allows labeling of O-linked β- N -acetylglucosamine-modified proteins via the N -acetylgalactosamine salvage pathway
2011 StandoutNobel
MicroRNA-155 Promotes Resolution of Hypoxia-Inducible Factor 1α Activity during Prolonged Hypoxia
2011
Small GTP-Binding Proteins
2001 Standout
Ago HITS-CLIP Expands Understanding of Kaposi's Sarcoma-associated Herpesvirus miRNA Function in Primary Effusion Lymphomas
2012
HOW CELLS RESPOND TO INTERFERONS
1998 Standout
Nods, Nalps and Naip: intracellular regulators of bacterial-induced inflammation
2003
HIV Gag protein conjugated to a Toll-like receptor 7/8 agonist improves the magnitude and quality of Th1 and CD8+T cell responses in nonhuman primates
2005
Sec24 Proteins and Sorting at the Endoplasmic Reticulum
1999
Interferon consensus sequence-binding protein, a member of the interferon regulatory factor family, suppresses interferon-induced gene transcription.
1993
Role of cytoplasmic C-terminal amino acids of membrane proteins in ER export
2002
Engagement of myelomonocytic Siglecs by tumor-associated ligands modulates the innate immune response to cancer
2014
DrosophilaRegulatory factor X is necessary for ciliated sensory neuron differentiation
2002
Enhancer I Predominance in Hepatitis B Virus Gene Expression
2004
How to drain without lymphatics? Dendritic cells migrate from the cerebrospinal fluid to the B-cell follicles of cervical lymph nodes
2005
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
CELLULAR RESPONSES TO INTERFERON-γ
1997 Standout
Precision glycocalyx editing as a strategy for cancer immunotherapy
2016 StandoutNobel
Cargo Selection by the COPII Budding Machinery during Export from the ER
1998
Sequences and Factors: A Guide to MHC Class-II Transcription
1992
Initiation of Immune Responses in Brain Is Promoted by Local Dendritic Cells
2004
Maintenance of in Vivo Tolerance by Persistence of Antigen
1992 StandoutScienceNobel
Analysis of xbx genes in C. elegans
2005 StandoutNobel
Brain Dendritic Cells and Macrophages/Microglia in Central Nervous System Inflammation
2001
Nucleation of COPII Vesicular Coat Complex by Endoplasmic Reticulum to Golgi Vesicle SNAREs
1998 StandoutScienceNobel
Histone H3K27ac separates active from poised enhancers and predicts developmental state
2010 Standout
gp25L/emp24/p24 Protein Family Members of the cis-Golgi Network Bind Both COP I and II Coatomer
1998
Lst1p and Sec24p Cooperate in Sorting of the Plasma Membrane Atpase into Copii Vesicles in Saccharomyces cerevisiae
2000 StandoutNobel
Identification of the putative mammalian orthologue of Sec31P, a component of the COPII coat
1999
The microbial mimic poly IC induces durable and protective CD4+T cell immunity together with a dendritic cell targeted vaccine
2008 StandoutNobel
Systemic Activation of NRF2 Alleviates Lethal Autoimmune Inflammation in Scurfy Mice
2017 StandoutNobel
Defective Lymphoid Development in Mice Lacking Jak3
1995 StandoutScienceNobel
CATERPILLER: A Novel Gene Family Important in Immunity, Cell Death, and Diseases
2004

Works of Walter Reith being referenced

Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria–specific CD4 + T cells
2015 Science
Mini‐review: Specificity and expression of CIITA, the master regulator of MHC class II genes
2004
Cyclin E2: a novel CDK2 partner in the late G1 and S phases of the mammalian cell cycle
1998
MHC Class II‐Deficient Combined Immunodeficiency: A Disease of Gene Regulation
1994
Conditional gene targeting in macrophages and granulocytes using LysMcre mice
1999 Standout
The brain as an immune privileged site: dendritic cells of the central nervous system inhibit T cell activation
2003
RFX Proteins, a Novel Family of DNA Binding Proteins Conserved in the Eukaryotic Kingdom
1996
Dendritic cells and differential usage of the MHC class II transactivator promoters in the central nervous system in experimental autoimmune encephalitis
2000
Structure of the winged-helix protein hRFX1 reveals a new mode of DNA binding
2000 Nature
A gene encoding a novel RFX-associated transactivator is mutated in the majority of MHC class II deficiency patients
1998
MHC class II expression is differentially regulated in plasmacytoid and conventional dendritic cells
2004
Regulatory factor-X binding to mutant HLA-DRA promoter sequences
1991
Congenital immunodeficiency with a regulatory defect in MHC class II gene expression lacks a specific HLA-DR promoter binding protein, RF-X
1988
The Bare Lymphocyte Syndrome and the Regulation of MHC Expression
2001
Two DNA-binding proteins discriminate between the promoters of different members of the major histocompatibility complex class II multigene family.
1990
RFX1, a transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins.
1994
A Consensus Motif in the RFX DNA Binding Domain and Binding Domain Mutants with Altered Specificity
1996
MHC class II regulatory factor RFX has a novel DNA-binding domain and a functionally independent dimerization domain.
1990
CIITA Leucine-Rich Repeats Control Nuclear Localization, In Vivo Recruitment to the Major Histocompatibility Complex (MHC) Class II Enhanceosome, and MHC Class II Gene Transactivation
2000
The Transcription Factor RFX3 Directs Nodal Cilium Development and Left-Right Asymmetry Specification
2004
REGULATION OF MHC CLASS II GENES: Lessons from a Disease
1996
Induction of HLA class II genes by IFN-gamma is transcriptional and requires a trans-acting protein.
1989
MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells
2009
RFX1 is identical to enhancer factor C and functions as a transactivator of the hepatitis B virus enhancer.
1993
CIITA is a transcriptional coactivator that is recruited to MHC class II promoters by multiple synergistic interactions with an enhanceosome complex
2000
RFX1 is Identical to Enhancer Factor C and Functions as a Transactivator of the Hepatitis B Virus Enhancer
1993
Silencing of c-Fos expression by microRNA-155 is critical for dendritic cell maturation and function
2011
Cloning of the major histocompatibility complex class II promoter binding protein affected in a hereditary defect in class II gene regulation.
1989
Cloning and functional characterization of mammalian homologues of the COPII component Sec23.
1996 StandoutNobel
Rankless by CCL
2026