Citation Impact
Citing Papers
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins
2013 StandoutScienceNobel
Activation of Stat3 in Human Melanoma Promotes Brain Metastasis
2006
Induction of interferon-stimulated gene expression and antiviral responses require protein deacetylase activity
2004 StandoutNobel
Hierarchical design of pseudosymmetric protein nanocages
2024 StandoutNatureNobel
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
Transforming Growth Factor (TGF)-β1 Internalization
2001
Stat3 regulates genes common to both wound healing and cancer
2005
HIV-1 infection of nondividing cells: C-terminal tyrosine phosphorylation of the viral matrix protein is a key regulator
1995
Differential contributions of ERK and PI3-kinase to the regulation of cyclin D1 expression and to the control of the G1/S transition in mouse embryonic stem cells
2002
Inhibition of Bcr–Abl kinase activity by PD180970 blocks constitutive activation of Stat5 and growth of CML cells
2002
Phosphorylation of Cell Surface Receptors: A Mechanism for Regulating Signal Transduction Pathways
1988 StandoutNobel
Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells
2003
SV40 T antigen alone drives karyotype instability that precedes neoplastic transformation of human diploid fibroblasts
1990
JAKs, STATs and Src kinases in hematopoiesis
2002
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
A Spatial-Temporal Model of Cell Activation
1988 Science
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
2006 StandoutNobel
Differentiation of trophoblast endocrine cells
1996
Nanocaged platforms: modification, drug delivery and nanotoxicity. Opening synthetic cages to release the tiger
2016
Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
2007 StandoutNobel
Heterochronic Genes Control Cell Cycle Progress and Developmental Competence of C. elegans Vulva Precursor Cells
1996 StandoutNobel
Telomere states and cell fates
2000 StandoutNatureNobel
Mechanisms of Disease: insights into the emerging role of signal transducers and activators of transcription in cancer
2005
Telomeres shorten during ageing of human fibroblasts
1990 StandoutNatureNobel
Src Kinases Mediate STAT Growth Pathways in Squamous Cell Carcinoma of the Head and Neck
2003
Regulated expression and phosphorylation of a possible mammalian cell-cycle control protein
1988 StandoutNatureNobel
HIV-1 Genome Nuclear Import Is Mediated by a Central DNA Flap
2000 StandoutNobel
Runaway telomere elongation caused by telomerase RNA gene mutations
1995 StandoutNatureNobel
A Novel Platinum Compound Inhibits Constitutive Stat3 Signaling and Induces Cell Cycle Arrest and Apoptosis of Malignant Cells
2005
Bioengineered protein-based nanocage for drug delivery
2016
Purified maturation-promoting factor contains the product of a Xenopus homolog of the fission yeast cell cycle control gene cdc2+
1988 StandoutNobel
Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice
1999 StandoutNobel
Generation of germline-competent induced pluripotent stem cells
2007 StandoutNatureNobel
Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis
2002
HIV infection does not require endocytosis of its receptor, CD4
1988 StandoutNobel
cAMP contributes to mossy fiber LTP by initiating both a covalently mediated early phase and macromolecular synthesis-dependent late phase
1994 StandoutNobel
STATs in cancer inflammation and immunity: a leading role for STAT3
2009 Standout
Co-operative Effect of c-Src Tyrosine Kinase and Stat3 in Activation of Hepatocyte Growth Factor Expression in Mammary Carcinoma Cells
2001
Anaplastic lymphoma kinase (ALK) activates Stat3 and protects hematopoietic cells from cell death
2002
STAT proteins: novel molecular targets for cancer drug discovery
2000
Deletion of the SOCS3 Gene in Liver Parenchymal Cells Promotes Hepatitis–Induced Hepatocarcinogenesis
2006
The STATs of cancer — new molecular targets come of age
2004 Standout
Roles of activated Src and Stat3 signaling in melanoma tumor cell growth
2002
Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment
2006
TGFα deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice
1993 StandoutNobel
Cancer-related inflammation
2008 StandoutNature
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
The pathogenesis of atherosclerosis: a perspective for the 1990s
1993 StandoutNature
Barrett's esophagus: Cell cycle abnormalities in advancing stages of neoplastic progression
1993
Activation of Stat3 by receptor tyrosine kinases and cytokines regulates survival in human non-small cell carcinoma cells
2003
STATs: transcriptional control and biological impact
2002 Standout
Development of Virus-Like Particle Technology from Small Highly Symmetric to Large Complex Virus-Like Particle Structures
2013 Standout
Molecular Characterization of a Functional cDNA Encoding the Serotonin 1c Receptor
1988 StandoutScienceNobel
Neuroendocrine Modulation of Signal Transducer and Activator of Transcription-3 in Ovarian Cancer
2007
Telomere length predicts replicative capacity of human fibroblasts.
1992 StandoutNobel
Cell-cycle control of c-myc but not c-ras expression is lost following chemical transformation
1984
Involvement of tyrosine residues located in the carboxyl tail of the human beta 2-adrenergic receptor in agonist-induced down-regulation of the receptor.
1990 StandoutNobel
Homologies Between Signal Transducing G Proteins and ras Gene Products
1984 StandoutScienceNobel
The long and the short of long–term memory—a molecular framework
1986 StandoutNatureNobel
Knockdown of STAT3 Expression by RNA Interference Inhibits the Induction of Breast Tumors in Immunocompetent Mice
2005
Photoexpulsion of Surface-Grafted Ruthenium Complexes and Subsequent Release of Cytotoxic Cargos to Cancer Cells from Mesoporous Silica Nanoparticles
2013 StandoutNobel
Hyperactivation of STAT3 Is Involved in Abnormal Differentiation of Dendritic Cells in Cancer
2004
Epidermal growth factor (EGF) is required only during the traverse of early G1 in PDGF stimulated density-arrested BALB/c-3T3 cells
1983
Similar action of platelet‐derived growth factor and epidermal growth factor in the prereplicative phase of human fibroblasts suggests a common intracellular pathway
1985
Three restriction points in the cell cycle of activated murine B lymphocytes.
1985
Platelet-derived growth factor mimics phorbol diester action on epidermal growth factor receptor phosphorylation at threonine-654.
1985
Platelet-derived growth factor treatment decreases the affinity of the epidermal growth factor receptors of Swiss 3T3 cells.
1983
beta-Adrenergic regulation of insulin and epidermal growth factor receptors in rat adipocytes.
1983
Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor
1983 Standout
Regulation of transmembrane signaling by receptor phosphorylation
1987 StandoutNobel
Protein kinase C phosphorylation at Thr 654 of the unoccupied EGF receptor and EGF binding regulate functional receptor loss by independent mechanisms
1986
Purified human platelet-derived growth factor receptor has ligand-stimulated tyrosine kinase activity.
1986
Ectopic Expression of the Serotonin 1c Receptor and the Triggering of Malignant Transformation
1989 StandoutScienceNobel
Inhibition of constitutive signal transducer and activator of transcription 3 activation by novel platinum complexes with potent antitumor activity
2004
Functional role for c-myc in mitogenic response to platelet-derived growth factor
1984 Nature
Nucleotide sequence of the human N-myc gene.
1986 StandoutNobel
Relationship between donor age and the replicative lifespan of human cells in culture: A reevaluation
1998
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
BET bromodomain inhibition targets both c-Myc and IL7R in high-risk acute lymphoblastic leukemia
2012
Early Signals in the Mitogenic Response
1986 Science
Novel peptidomimetic inhibitors of signal transducer and activator of transcription 3 dimerization and biological activity
2004
Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability
2009 StandoutNobel
Resveratrol inhibits Src and Stat3 signaling and induces the apoptosis of malignant cells containing activated Stat3 protein
2006
Effect of prostaglandin E1 on DNA synthesis in vascular smooth muscle cells
1986
Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention.
2002
Activation of PI3K/Akt and MAPK pathways regulates Myc-mediated transcription by phosphorylating and promoting the degradation of Mad1
2008
Activation of a translocated c-myc gene: role of structural alterations in the upstream region.
1984 StandoutNobel
Cellular Senescence revisited: a review
1987
Stimulation of aortic smooth muscle cell mitogenesis by serotonin.
1986
Growth Factors and Cancer
1991 StandoutScience
Developmental and tissue-specific regulation of mouse telomerase and telomere length.
1995 StandoutNobel
G 1 Events and Regulation of Cell Proliferation
1989 StandoutScience
Nuclear interaction of EGFR and STAT3 in the activation of the iNOS/NO pathway
2005
Post-transcriptional control of the onset of DNA synthesis by an insulin-like growth factor.
1984
Cell cycle controls in higher eukaryotic cells: Resting state or a prolonged G1 period?
1986
LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism
2005
Cellular redistribution of β‐adrenergic receptors in a human astrocytoma cell line: A comparison with the epidermal growth factor receptor in murine fibroblasts
1985
Immunotherapy: Bewitched, Bothered, and Bewildered No More
2004 StandoutScienceNobel
The RNA Component of Human Telomerase
1995 StandoutScienceNobel
Gene expression during the mammalian cell cycle
1986
Design of a hyperstable 60-subunit protein icosahedron
2016 StandoutNatureNobel
A significant part of macrophage-derived growth factor consists of at least two forms of PDGF
1985
Combinatorial Peptide Libraries: Mining for Cell-Binding Peptides
2013
Restoration of Telomeres in Human Papillomavirus-Immortalized Human Anogenital Epithelial Cells
1994
Regulation of thymidine kinase activity in the cell cycle by a labile protein
1985
Inhibition of STAT3 signaling induces apoptosis and decreases survivin expression in primary effusion lymphoma
2003
Epidermal Growth Factor Receptor Cooperates with Signal Transducer and Activator of Transcription 3 to Induce Epithelial-Mesenchymal Transition in Cancer Cells via Up-regulation of TWIST Gene Expression
2007
Restoration of telomeres in human papillomavirus-immortalized human anogenital epithelial cells.
1994
Diacylglycerol modulates binding and phosphorylation of the epidermal growth factor receptor.
1984
Kinetics of G1 transit following brief starvation for serum factors
1984
Expression of N-myc in teratocarcinoma stem cells and mouse embryos
1985 StandoutNatureNobel
The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia
2016 Standout
Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells
2001
Molecules involved in proliferation of normal and cancer cells: presidential address.
1987
Molecular cloning of gene sequences regulated by platelet-derived growth factor
1983
The protein encoded by the human proto-oncogene c-myc.
1984 StandoutNobel
Constitutive activation of Stat3 in human prostate tumors and cell lines: direct inhibition of Stat3 signaling induces apoptosis of prostate cancer cells.
2002
ß-Arrestin 2 Mediates Endocytosis of Type III TGF-ß Receptor and Down-Regulation of Its Signaling
2003 StandoutScienceNobel
Wound Macrophages Express TGF-α and Other Growth Factors in Vivo: Analysis by mRNA Phenotyping
1988 Science
Insulin‐like growth factor I regulation of transcription and replicating enzyme induction necessary for DNA synthesis
1986
Works of Walker Wharton being referenced
Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia
2010
Characterization of the rebinding of 125I‐epidermal growth factor released from BALB/c‐3T3 cells following accumulation in the presence of chloroquine
1988
Induction of p21WAF1/CIP1 and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts: role of activated STAT3 signaling
2000
Western blot detection of epidermal growth factor receptor from plasmalemma of culture cells using 125I-labeled epidermal growth factor
1987
Activation of Stat3 preassembled with platelet-derived growth factor β receptors requires Src kinase activity
2000
Dissociation of cellular transformation from platelet‐derived growth factor independence
1986
Modulation of the epidermal growth factor receptor by platelet-derived growth factor and choleragen: Effects on mitogenesis
1982
Newborn human skin fibroblasts senesce in vitro without acquiring adult growth factor requirements*1
1984
Mitogenic activity elaborated by macrophage‐like cell lines acts as competence factor(s) for BALB/c 3T3 cells
1982
Isolation of cell membrane for epidermal growth factor receptor studies
1991
Epidermal growth factor (EGF) and somatomedin C regulate G1 progression in competent BALB/c-3T3 cells
1982
Proadipocyte cell lines: models of cellular proliferation and differentiation
1993
Delivery of Small Interfering RNA by Peptide-Targeted Mesoporous Silica Nanoparticle-Supported Lipid Bilayers
2012
Elevated intracellular concentrations of cyclic AMP inhibited serum‐stimulated, density‐arrested BALB/c‐3T3 cells in mid G1
1982
Increases in cyclic AMP potentiate competence formation in BALB/c‐3T3 cells
1982
Inhibition of BALB/c‐3T3 cells in late G1: Commitment to DNA synthesis controlled by somatomedin C
1981
A method for staining 3T3 cell nuclei with propidium iodide in hypotonic solution
1983
Regulation of uridine kinase activity in BLAB/C-3T3 cells by serum components
1981
Cell-Specific Delivery of Diverse Cargos by Bacteriophage MS2 Virus-like Particles
2011
Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis
2001