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Citing Papers
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
2003 StandoutNobel
Functional diversity of helper T lymphocytes
1996 StandoutNature
A role for CD95 ligand in preventing graft rejection
1995 StandoutNature
Analysis of Expression of Lymphocyte Homing-Related Adhesion Molecules in ALY Mice Deficient in Lymph Nodes and Peyer's Patches
1997
Correction of the TNF‐LTα‐Deficient Phenotype by Bone Marrow Transplantation
1997
Tumoricidal activity of tumor necrosis factor–related apoptosis–inducing ligand in vivo
1999 Standout
FADD, a novel death domain-containing protein, interacts with the death domain of fas and initiates apoptosis
1995 Standout
TRAF5, an Activator of NF-κB and Putative Signal Transducer for the Lymphotoxin-β Receptor
1996
5′-Flanking Sequences in Thyroid Hormone Response Element Half-sites Determine the Requirement of Retinoid X Receptor for Receptor-mediated Gene Expression
1997
Activated T Cell Death In Vivo Mediated by Proapoptotic Bcl-2 Family Member Bim
2002
Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-κb-inducing kinase
1999 StandoutNobel
Resistance of cultured peripheral T cells towards activation‐induced cell death involves a lack of recruitment of FLICE (MACH/caspase 8) to the CD95 death‐inducing signaling complex
1997
Proteolysis of Fodrin (Non-erythroid Spectrin) during Apoptosis
1995
Identification of the transforming EML4–ALK fusion gene in non-small-cell lung cancer
2007 StandoutNature
The Lymphotoxin β Receptor Controls Organogenesis and Affinity Maturation in Peripheral Lymphoid Tissues
1998 Standout
Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
1998 StandoutNatureNobel
Reduction of arthritis and pneumonitis in motheaten mice by soluble tumor necrosis factor receptor
1998
Tolerance and Autoimmunity
2001
Human autoimmune lymphoproliferative syndrome, a defect in the apoptosis-inducing Fas receptor: A lesson from the mouse model
1998
The Lymphotoxin-β Receptor Induces Different Patterns of Gene Expression via Two NF-κB Pathways
2002
Fas (CD95)/Fas ligand interactions regulate antigen‐specific, major histocompatibility complex‐restricted T/B cell proliferative responses
1996
Induction of peripheral CD8+ T‐cell tolerance by cross‐presentation of self antigens
1998 StandoutNobel
New advances in understanding the molecular mechanisms of thyroid hormone action
1994
Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment
1995
Lymphoid organ development: from ontogeny to neogenesis
2006
The Roles of Fas/APO-1 (CD95) and TNF in Antigen-Induced Programmed Cell Death in T Cell Receptor Transgenic Mice
1996
TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL
1997
Caspase activity is required for commitment to Fas-mediated apoptosis
1997
Expansion or Elimination of B Cells In Vivo: Dual Roles for CD40- and Fas (CD95)-Ligands Modulated by the B Cell Antigen Receptor
1996
Characterization of the Promoter of the Rat Sarcoplasmic Endoplasmic Reticulum Ca2+-ATPase 1 Gene and Analysis of Thyroid Hormone Responsiveness
1996
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
1999 StandoutNature
Mechanisms underlying T-cell tolerance
1996
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
1995 StandoutNature
Transcriptional Regulatory Patterns of the Myelin Basic Protein and Malic Enzyme Genes by the Thyroid Hormone Receptors α1 and β1
1998
Insulin signalling and the regulation of glucose and lipid metabolism
2001 StandoutNature
Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs
1998 StandoutNature
Non-canonical inflammasome activation targets caspase-11
2011 StandoutNature
Origin and physiological roles of inflammation
2008 StandoutNature
The ST3Gal-I Sialyltransferase Controls CD8+ T Lymphocyte Homeostasis by Modulating O-Glycan Biosynthesis
2000
Mammalian MAP kinase signalling cascades
2001 StandoutNature
Induction of apoptosis in mature T cells by tumour necrosis factor
1995 Nature
Intrinsic Lymphotoxin-β Receptor Requirement for Homeostasis of Lymphoid Tissue Dendritic Cells
2005
AIDS and the death receptors
1997
A Novel Gene Product that Couples TCR Signaling to Fas(CD95) Expression in Activation-Induced Cell Death
1996
Instruction of Distinct CD4 T Helper Cell Fates by Different Notch Ligands on Antigen-Presenting Cells
2004 StandoutNobel
Elimination of Antigen-Presenting Cells and Autoreactive T Cells by Fas Contributes to Prevention of Autoimmunity
2007
A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
1998 StandoutNature
A Dominant Complement Fixation Pathway for Pneumococcal Polysaccharides Initiated by SIGN-R1 Interacting with C1q
2006 StandoutNobel
Points of control in inflammation
2002 StandoutNature
Dendritic cells and the control of immunity
1998 StandoutNatureNobel
The role of the bcl-2/ced-9 gene family in cancer and general implications of defects in cell death control for tumourigenesis and resistance to chemotherapy
1997
Transforming activity of the lymphotoxin-β receptor revealed by expression screening
2005
Inhibition of death receptor signals by cellular FLIP
1997 StandoutNature
Autoimmune Lymphoproliferative Syndrome with Defective Fas: Genotype Influences Penetrance
1999
DNA Recognition by Normal and Oncogenic Thyroid Hormone Receptors
1996
Apoptosis and the maintenance of homoeostasis in the immune system
1996
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
Impaired apoptosis, extended duration of immune responses, and a lupus-like autoimmune disease in IEX-1-transgenic mice
2002 StandoutNobel
Altered Cytokine Export and Apoptosis in Mice Deficient in Interleukin-1β Converting Enzyme
1995 Science
Development of Monocytes, Macrophages, and Dendritic Cells
2010 StandoutScience
The Bcl-2 Protein Family: Arbiters of Cell Survival
1998 StandoutScience
Cancer Regression and Autoimmunity in Patients After Clonal Repopulation with Antitumor Lymphocytes
2002 StandoutScience
Ligand-dependent occupancy of the retinoic acid receptor beta 2 promoter in vivo.
1994
Delineation of three different thyroid hormone-response elements in promoter of rat sarcoplasmic reticulum Ca2+ATPase gene. Demonstration that retinoid X receptor binds 5' to thyroid hormone receptor in response element 1.
1994
Proteasome regulation of activation-induced T cell death
1997 StandoutNobel
Regulation of the Proinflammatory Effects of Fas Ligand (CD95L)
1998 Science
Lymphocyte Homing and Homeostasis
1996 StandoutScience
Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege
1995 StandoutScience
Apoptosis of nur77/N10-transgenic thymocytes involves the Fas/Fas ligand pathway.
1996
The C-type lectin SIGN-R1 mediates uptake of the capsular polysaccharide ofStreptococcus pneumoniaein the marginal zone of mouse spleen
2003 StandoutNobel
CrmA expression in T lymphocytes of transgenic mice inhibits CD95 (Fas/APO-1)-transduced apoptosis, but does not cause lymphadenopathy or autoimmune disease.
1996
Glucocorticoids in T Cell Development and Function
2000
Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl.
1995 Standout
Fas and Fas ligand in embryos and adult mice: ligand expression in several immune-privileged tissues and coexpression in adult tissues characterized by apoptotic cell turnover.
1996
Two distinctive pathways for recruitment of naïve and primed IgM+B cells to the gut lamina propria
2005 StandoutNobel
Human CD4+ T-cell response to hepatitis delta virus: identification of multiple epitopes and characterization of T-helper cytokine profiles
1997 StandoutNobel
Regulation of the Nur77 Orphan Steroid Receptor in Activation-Induced Apoptosis
1995
Death Receptors: Signaling and Modulation
1998 StandoutScience
Physiological and Molecular Basis of Thyroid Hormone Action
2001 Standout
Human nuclear receptor heterodimers: opportunities for detecting targets of transcriptional regulation using yeast.
1996
CD8+ T-cell selection, function, and death in the primary immune response in vivo
2000
Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger
2008 StandoutNobel
Surface lymphotoxin alpha/beta complex is required for the development of peripheral lymphoid organs.
1996
A subclass of dendritic cells kills CD4 T cells via Fas/Fas-ligand-induced apoptosis.
1996
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
Essential Role of Nuclear Factor (NF)-κB–Inducing Kinase and Inhibitor of κb (Iκb) Kinase α in Nf-κb Activation through Lymphotoxin β Receptor, but Not through Tumor Necrosis Factor Receptor I
2001
Fas Preassociation Required for Apoptosis Signaling and Dominant Inhibition by Pathogenic Mutations
2000 StandoutScienceNobel
Half-site arrangement of hybrid glucocorticoid and thyroid hormone response elements specifies thyroid hormone receptor complex binding to DNA and transcriptional activity.
1994
The Release of Cytochrome c from Mitochondria: A Primary Site for Bcl-2 Regulation of Apoptosis
1997 StandoutScience
Unliganded thyroid hormone receptor inhibits formation of a functional preinitiation complex: implications for active repression.
1993
T-Independent Immune Response: New Aspects of B Cell Biology
2000 StandoutScienceNobel
Essential Role of Insulin Receptor Substrate 1 in Differentiation of Brown Adipocytes
2001
Interleukin 1β-converting Enzyme Related Proteases/Caspases Are Involved in TRAIL-induced Apoptosis of Myeloma and Leukemia Cells
1997
MATURE T LYMPHOCYTE APOPTOSIS—Immune Regulation in a Dynamic and Unpredictable Antigenic Environment
1999
TUMOR NECROSIS FACTOR RECEPTOR AND Fas SIGNALING MECHANISMS
1999
The Peripheral Deletion of Autoreactive CD8+ T Cells Induced by Cross-presentation of Self-antigens Involves Signaling through CD95 (Fas, Apo-1)
1998
Intracellular Regulation of TRAIL-Induced Apoptosis in Human Melanoma Cells
1998
A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes
1998
Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
2008 StandoutNobel
The immunobiology of TSE diseases
2001
THE UBIQUITIN SYSTEM
1998 StandoutNobel
TRAF-4 expression in epithelial progenitor cells. Analysis in normal adult, fetal, and tumor tissues.
1998
Suppression of TNF-α-Induced Apoptosis by NF-κB
1996 StandoutScience
Withdrawal of Survival Factors Results in Activation of the JNK Pathway in Neuronal Cells Leading to Fas Ligand Induction and Cell Death
1999
Macrophage-dependent Apoptosis of CD4+ T Lymphocytes from HIV-infected Individuals Is Mediated by FasL and Tumor Necrosis Factor
1997
Adenovirus-mediated gene delivery and in vitro microinsemination produce offspring from infertile male mice
2002 StandoutNobel
In Vivo Genomic Footprinting of Thyroid Hormone-Responsive Genes in Pituitary Tumor Cell Lines
1996
TNF- and Cancer Therapy-Induced Apoptosis: Potentiation by Inhibition of NF-κB
1996 StandoutScience
Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis.
1995
Works of Walker R. Force being referenced
Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas
1995 Nature
Dominant Negative Mutants of TRAF3 Reveal an Important Role for the Coiled Coil Domains in Cell Death Signaling by the Lymphotoxin-β Receptor
1997
Discrete Signaling Regions in the Lymphotoxin-β Receptor for Tumor Necrosis Factor Receptor-associated Factor Binding, Subcellular Localization, and Activation of Cell Death and NF-κB Pathways
2000
Mouse lymphotoxin-beta receptor. Molecular genetics, ligand binding, and expression.
1995
Homodimer and heterodimer DNA binding and transcriptional responsiveness to triiodothyronine (T3) and 9-cis-retinoic acid are determined by the number and order of high affinity half-sites in a T3 response element.
1994
Positive and negative thyroid hormone response elements are composed of strong and weak half-sites 10 nucleotides in length.
1992
3,5,3'-L-triiodothyronine (thyroid hormone)-induced protein-DNA interactions in the thyroid hormone response elements and cell type-specific elements of the rat growth hormone gene revealed by in vivo dimethyl sulfate footprinting
1994
Lymphotoxin-β receptor signaling complex: Role of tumor necrosis factor receptor-associated factor 3 recruitment in cell death and activation of nuclear factor κB
1997