Standout Papers
Citation Impact
Citing Papers
Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro
2006 StandoutNobel
Neutralizing antibody response during acute and chronic hepatitis C virus infection
2004 StandoutNobel
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
Uracil DNA Glycosylase Activity Is Dispensable for Immunoglobulin Class Switch
2004 StandoutScienceNobel
Mouse models of acute and chronic hepacivirus infection
2017 StandoutScienceNobel
The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins
2013 StandoutScienceNobel
Stepwise progression of B lineage differentiation supported by interleukin 7 and other stromal cell molecules.
1990
Expansive discovery of chemically diverse structured macrocyclic oligoamides
2024 StandoutScienceNobel
Cancer immunoediting: from immunosurveillance to tumor escape
2002 Standout
SEC14L2 enables pan-genotype HCV replication in cell culture
2015 StandoutNatureNobel
The Mechanism of V(D)J Joining: Lessons from Molecular, Immunological, and Comparative Analyses
1994
IgH Class Switch Recombination to IgG1 in DNA-PKcs-Deficient B Cells
2002
The mechanism of V(D)J recombination: A balance of diversity, specificity, and stability
1992
The SCID Mouse Mutant: Definition, Characterization, and Potential Uses
1991
The V(D)J recombination activating gene, RAG-1
1989 Nobel
Ku80 is required for immunoglobulin isotype switching
1998
Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation
1995
Molecular and cellular origins of B lymphocyte diversity
1991
Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cells
1988 Nature
V(D)J Recombination: Molecular Biology and Regulation
1992
AID Is Required for c-myc/IgH Chromosome Translocations In Vivo
2004 StandoutNobel
V(D)J recombination: Broken DNA molecules with covalently sealed (hairpin) coding ends in scid mouse thymocytes
1992
Mutations in the DNA ligase I gene of an individual with immunodeficiencies and cellular hypersensitivity to DNA-damaging agents
1992 StandoutNobel
The AID enzyme induces class switch recombination in fibroblasts
2002 StandoutNatureNobel
The Oncogenic Cysteine-rich LIM domain protein Rbtn2 is essential for erythroid development
1994 StandoutNobel
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
2011 StandoutNatureNobel
Circular DNA is excised by immunoglobulin class switch recombination
1990 StandoutNobel
Dendritic cells: emerging pharmacological targets of immunosuppressive drugs
2004
MX2 is an interferon-induced inhibitor of HIV-1 infection
2013 StandoutNatureNobel
Early B-cell precursors in scid mice: Normal numbers of cells transformable with abelson murine leukemia virus (A-MuLV)
1988
Taking dendritic cells into medicine
2007 StandoutNatureNobel
A developmental switch in thymic lymphocyte maturation potential occurs at the level of hematopoietic stem cells
1990
The scid mutation in mice causes a general defect in DNA repair
1990 Nature
In situ class switching and differentiation to IgA-producing cells in the gut lamina propria
2001 StandoutNatureNobel
A Multigene Family Encoding a Diverse Array of Putative Pheromone Receptors in Mammals
1997 StandoutNobel
Virus-induced autoantibody response to a transgenic viral antigen
1990 StandoutNatureNobel
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
The scid defect affects the final step of the immunoglobulin VDJ recombinase mechanism
1988
Thymic selection in CD8 transgenic mice supports an instructive model for commitment to a CD4 or CD8 lineage
1991 StandoutNobel
Antigen-induced apoptotic death of Ly-1 B cells responsible for autoimmune disease in transgenic mice
1992 StandoutNatureNobel
V(D)J recombination in mouse thymocytes: Double-strand breaks near T cell receptor δ rearrangement signals
1992
The exploration of macrocycles for drug discovery — an underexploited structural class
2008
Genetic interaction between PARP and DNA-PK in V(D)J recombination and tumorigenesis
1997
Everolimus for the Prevention of Allograft Rejection and Vasculopathy in Cardiac-Transplant Recipients
2003 Standout
DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis
2020 StandoutNatureNobel
The role of short homology repeats and TdT in generation of the invariant γδ antigen receptor repertoire in the fetal thymus
1995 StandoutNobel
The HCV Life Cycle: In vitro Tissue Culture Systems and Therapeutic Targets
2014 Standout
Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting
2012 StandoutNatureNobel
Distinct antigen receptor repertoires of two classes of murine epithelium-associated T cells
1989 StandoutNatureNobel
RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement
1992 Standout
The mechanism of antigen receptor gene assembly
1989
Recent Advances in Understanding V(D)J Recombination
1997
Experimental Models for Understanding B Lymphocyte Formation
1987
Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme
2000 StandoutNobel
Extrathymic positive selection of αβ T-cell precursors in nude mice
1992 StandoutNatureNobel
AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching
2001 StandoutNatureNobel
The defect in murine severe combined immune deficiency: Joining of signal sequences but not coding segments in V(D)J recombination
1988
Limited diversity of γδ antigen receptor genes of thy-1+ dendritic epidermal cells
1988 StandoutNobel
Mitogen- and IL-4-regulated expression of germ-line Ig γ2b transcripts: Evidence for directed heavy chain class switching
1988
Hepatitis C Virus RNA Functionally Sequesters miR-122
2015 StandoutNobel
T-lymphocyte development in scid mice is arrested shortly after the initiation of T-cell receptor delta gene recombination.
1991
Two gut intraepithelial CD8+ lymphocyte populations with different T cell receptors: a role for the gut epithelium in T cell differentiation.
1991
Generation of Lymphohematopoietic Cells from Embryonic Stem Cells in Culture
1994 StandoutScienceNobel
Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles
2003 StandoutNobel
Synthesis and metabolism of a histamine metabolite, 1-methyl-4-(β-aminoethyl)-imidazole
1958
A link between double-strand break-related repair and V(D)J recombination: the scid mutation.
1991
In vitro repair of oxidative DNA damage by human nucleotide excision repair system: Possible explanation for neurodegeneration in Xeroderma pigmentosum patients
1997 StandoutNobel
T-cell receptor gene rearrangements in functional T-cell clones from severe combined immune deficient (scid) mice: reversion of the scid phenotype in individual lymphocyte progenitors.
1990
Differentiation of growth signal requirement of B lymphocyte precursor is directed by expression of immunoglobulin.
1991 StandoutNobel
Strand breaks without DNA rearrangement in V (D)J recombination.
1991
Quality Control by DNA Repair
1999 StandoutScienceNobel
The scid gene encodes a trans-acting factor that mediates the rejoining event of Ig gene rearrangement.
1988
Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus
2012 StandoutNobel
Isolation of scid pre-B cells that rearrange kappa light chain genes: formation of normal signal and abnormal coding joins.
1989
Analysis of the repertoire of anti‐(4‐hydroxy‐3‐nitro‐phenyl)acetyl (NP) antibodies in C 57 BL/6 mice by cell fusion. II. Characterization of idiotopes by monoclonal anti‐idiotope antibodies
1979
Mutations in the p53 and SCID genes cooperate in tumorigenesis.
1996
T cell receptor gamma and delta gene junctional sequences in SCID mice: excessive P nucleotide insertion.
1991
Cis−Trans Isomerization of Organic Molecules and Biomolecules: Implications and Applications
2003
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Genomic organization of mouse J kappa recombination signal binding protein (RBP-J kappa) gene.
1992 StandoutNobel
Recognition of Self Antigens by Skin-Derived T Cells with Invariant γδ Antigen Receptors
1991 StandoutScienceNobel
Normal Development of Mice Deficient in β 2 M, MCClass I Proteins, and CD8 + T Cells
1990 StandoutScienceNobel
Cellular cofactors affecting hepatitis C virus infection and replication
2007 StandoutNobel
Analysis of Lymphoid Population in Scid Mice; Detection of a Potential B Lymphocyte Progenitor Population Present at Normal Levels in Scid Mice by Three Color Flow Cytometry With B220 and S7
1989
The absolute number of trans-rearrangements between the TCRG and TCRB loci is predictive of lymphoma risk: a severe combined immune deficiency (SCID) murine model.
1997
V(D)J recombination coding junction formation without DNA homology: processing of coding termini.
1993
Enzymatic N-Methylation of Histamine
1959 StandoutNatureNobel
Clearance of replicating hepatitis C virus replicon RNAs in cell culture by small interfering RNAs
2002 StandoutNobel
Histamine catabolism by cat liver homogenates
1958
Wild-type V(D)J recombination in scid pre-B cells.
1990
Activation of naïve B lymphocytes via CD81, a pathogenetic mechanism for hepatitis C virus-associated B lymphocyte disorders
2005 StandoutNobel
Molecular Characterization of the Lymphoid V(D) J Recombination Activity
1989
Target Cell Cyclophilin A Modulates Human Immunodeficiency Virus Type 1 Infectivity
2004
Replacing the complementarity-determining regions in a human antibody with those from a mouse
1986 StandoutNatureNobel
scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair.
1991
Entry‐into‐human study with the novel immunosuppressant SDZ RAD in stable renal transplant recipients
1999
Defect of Scid Mouse Revealed in In Vitro Culture Systems
1989
Thymic selection of H-2-incompatible bone marrow cells in SCID mice. Differences in T help for induction of B cell IgG responses versus cytotoxic T cells.
1988
Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation.
1990
Lenalidomide efficacy in activated B ‐cell‐like subtype diffuse large B ‐cell lymphoma is dependent upon IRF 4 and cereblon expression
2012
Structure and function of anti-DNA autoantibodies derived from a single autoimmune mouse.
1987
Normal recombination substrate VH to DJH rearrangements in pre-B cell lines from scid mice.
1990
Works of W. Schüler being referenced
Protein Kinase C Inhibitor Sotrastaurin Selectively Inhibits the Growth of CD79 Mutant Diffuse Large B-Cell Lymphomas
2011
Antascomicins A, B, C, D and E. Novel FKBP12 Binding Compounds from a Micromonospora Strain.
1996
Cymbimicin A and B, Two Novel Cyclophilin-binding Structures Isolated from Actinomycetes.
1997
Sanglifehrins A, B, C and D, Novel Cyclophilin-binding Compounds Isolated from Streptomyces sp. A92-308110. I. Taxonomy, Fermentation, Isolation and Biological Activity.
1999
SDZ RAD, A NEW RAPAMYCIN DERIVATIVE
1997 Standout
Defective V‐to‐J recombination of T cell receptor γ chain genes in scid mice
1990
Coding joint formation of endogenous T cell receptor genes in lymphoid cells from scid mice: unusual P‐nucleotide additions in VJ‐coding joints
1991
SDZ RAD inhibits cold ischemia-induced vascular remodeling
1999
Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency
1986
Nature of the scid Defect: A Defective VDJ Recombinase System
1989
The scid Mouse Mutant
1988
Sanglifehrin A, a Novel Cyclophilin-Binding Compound Showing Immunosuppressive Activity with a New Mechanism of Action
2001
Characterization of syngeneic anti‐idiotypic antibody against the idiotype of BALB/c myeloma protein J558
1977
Zur Hemmung der Diaminooxydase (Histaminase)
1952
Abnormal recombination of Igh D and J gene segments in transformed pre-B cells of scid mice.
1988
T cell receptor genes do not rearrange or express functional transcripts in natural killer cells of scid mice.
1987
Further evidence against random polyclonal antibody formation in mice with lupus-like graft-vs-host disease.
1984
Transcription of unrearranged antigen receptor genes in scid mice.
1988