Citation Impact
Citing Papers
Thalidomide induces limb defects by preventing angiogenic outgrowth during early limb formation
2009
Identification of a Primary Target of Thalidomide Teratogenicity
2010 StandoutScience
Congenital Heart Disease in the General Population
2007 Standout
HIF Hydroxylase Pathways in Cardiovascular Physiology and Medicine
2015 StandoutNobel
Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes.
1991 Standout
Killing Me Softly: The Fetal Origins Hypothesis
2011
Fetal alcohol syndrome in dizygotic twins
1975
DisGeNET: a comprehensive platform integrating information on human disease-associated genes and variants
2016 Standout
Mutations of PVRL1, encoding a cell-cell adhesion molecule/herpesvirus receptor, in cleft lip/palate-ectodermal dysplasia
2000 Standout
Medical genetics in Hungary.
1988
Maternal Smoking, Body Mass Index, and Neural Tube Defects
1998
Clinical translation of angiogenesis inhibitors
2002 Standout
Mendelian randomization: can genetic epidemiology help redress the failures of observational epidemiology?
2007
Newborn Hearing Screening — A Silent Revolution
2006 Standout
Molecular mechanisms of cereblon-based drugs
2019
Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
1999 Standout
PHF8, a gene associated with cleft lip/palate and mental retardation, encodes for an Nε-dimethyl lysine demethylase
2009 StandoutNobel
Progesterone and the Risk of Preterm Birth among Women with a Short Cervix
2007 Standout
Mechanism of action of thalidomide and 3-aminothalidomide in multiple myeloma
2001
Multiple Myeloma
2004
Trends in the use of prenatal diagnosis in New York State and the impact of biochemical screening on the detection of Down syndrome: 1984–1993
1997
Mechanism of action in thalidomide teratogenesis
2000
The effect of hypoxia in development
2007
A structure-based computational workflow to predict liability and binding modes of small molecules to hERG
2020 StandoutNobel
Cleft lip and palate
2009 Standout
Birth prevalence study of the apert syndrome
1992
Wnt/β-Catenin Signaling and Disease
2012 Standout
Teratogen update: thalidomide: a review, with a focus on ocular findings and new potential uses
1999
Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
2009 Standout
FGF-21 as a novel metabolic regulator
2005 Standout
The cornified envelope: a model of cell death in the skin
2005 Standout
Apert syndrome results from localized mutations of FGFR2 and is allelic with Crouzon syndrome
1995 Standout
An E3 ligase guide to the galaxy of small-molecule-induced protein degradation
2021
Facial shape differences between rats selected for tame and aggressive behaviors
2017 StandoutNobel
Congenital malformations among infants whose mothers had gestational diabetes or preexisting diabetes
2001
Socioeconomic inequalities in risk of congenital anomaly
2000
Prevention of the First Occurrence of Neural-Tube Defects by Periconceptional Vitamin Supplementation
1992 Standout
Inhibition of NF-κB Activity by Thalidomide through Suppression of IκB Kinase Activity
2001
Deficiency of PORCN, a regulator of Wnt signaling, is associated with focal dermal hypoplasia
2007
Nongenital malformations following exposure to progestational drugs: The last chapter of an erroneous allegation
2005
Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases
2018 Standout
PROTAC targeted protein degraders: the past is prologue
2022 Standout
Perspectives on holoprosencephaly: Part I. Epidemiology, genetics, and syndromology
1989
Identification of Sonic hedgehog as a candidate gene responsible for holoprosencephaly
1996 Standout
Fraser syndrome and cryptophthalmos: review of the diagnostic criteria and evidence for phenotypic modules in complex malformation syndromes
2002
Heterozygous Germline Mutations in the p53 Homolog p63 Are the Cause of EEC Syndrome
1999
Maternal Overweight and Obesity and the Risk of Congenital Anomalies
2009 Standout
Thalidomide
2004
Development of targeted protein degradation therapeutics
2019
Fibroblast growth factors, their receptors and signaling.
2000
Antitumor Activity of Thalidomide in Refractory Multiple Myeloma
1999 Standout
S.T.E.P.S.™: A comprehensive program for controlling and monitoring access to thalidomide
1999
Down's syndrome
2003 Standout
In honor of the Teratology Society's 50th anniversary: The role of Teratology Society members in the development and evolution of in vivo developmental toxicity test guidelines
2010
Effects of Thalidomide and Related Metabolites in a Mouse Corneal Model of Neovascularization
1997
Free radical-mediated oxidative DNA damage in the mechanism of thalidomide teratogenicity
1999
Biochemical and genetic aspects of 7-dehydrocholesterol reductase and Smith-Lemli-Opitz syndrome
2000
Mutations in the human Sonic Hedgehog gene cause holoprosencephaly
1996 Standout
Expanding the arsenal of E3 ubiquitin ligases for proximity-induced protein degradation
2021
Cancer therapies based on targeted protein degradation — lessons learned with lenalidomide
2021
The primary cilium: a signalling centre during vertebrate development
2010 Standout
Effect of In Utero and Early-Life Conditions on Adult Health and Disease
2008 Standout
The first 30 years of p53: growing ever more complex
2009 Standout
Automatic Filtering and Substantiation of Drug Safety Signals
2012
Rett syndrome: exclusion mapping following the hypothesis of germinal mosaicism for new X-linked mutations
1991
Review on genetic variants and maternal smoking in the etiology of oral clefts and other birth defects
2008
Chapter 3. Role of Neurotransmitters in Palate Development
1984
Fluorine in medicinal chemistry
2007 Standout
Contribution of Organofluorine Compounds to Pharmaceuticals
2020 Standout
The Saga of Thalidomide
1962
Consumption of alcohol during pregnancy: a review of effects on growth and development of offspring.
1982
Association of congenital deafness with goitre (Pendred's syndrome): A study of 207 families
1964
Thalidomide induces limb deformities by perturbing the Bmp/Dkkl/Wnt signaling pathway
2007
Congenital malformations and environmental influences in pregnancy.
1969
Air Pollution and Cardiovascular Disease
2004 Standout
Socioeconomic Status and Child Development
2002 Standout
Self-disproportionation of enantiomers of thalidomide and its fluorinated analogue via gravity-driven achiral chromatography: mechanistic rationale and implications
2014
Congenital anomalies in twins.
1986
Mouse Otx2 functions in the formation and patterning of rostral head.
1995 Standout
Peptidic degron for IMiD-induced degradation of heterologous proteins
2019 StandoutNobel
The epidemiology of congenital heart disease
1965
The rise, fall and subsequent triumph of thalidomide: lessons learned in drug development
2011
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Thalidomide Pharmacokinetics and Metabolite Formation in Mice, Rabbits, and Multiple Myeloma Patients
2004
The extracellular matrix geneFrem1is essential for the normal adhesion of the embryonic epidermis
2004 StandoutNobel
Making sense of cilia in disease: The human ciliopathies
2009
Genetic identification of HSD-1, a conserved steroidogenic enzyme that directs larval development inCaenorhabditis elegans
2008 StandoutNobel
Decreasing the burden of congenital heart anomalies: an epidemiologic evaluation of risk factors and survival
2003
Hormones and Endocrine-Disrupting Chemicals: Low-Dose Effects and Nonmonotonic Dose Responses
2012 Standout
Dietary Carcinogens and Anticarcinogens
1983 StandoutScience
p63 identifies keratinocyte stem cells
2001 Standout
Thalidomide promotes degradation of SALL4, a transcription factor implicated in Duane Radial Ray syndrome
2018
The Control of Prostate-Specific Antigen Expression and Gene Regulation by Pharmacological Agents
2001
Impact of Natural Products on Developing New Anti-Cancer Agents
2009 Standout
Per- and polyfluoroalkyl substances in the environment
2022 StandoutScience
Multiple Myeloma
2011 Standout
The Saga of Thalidomide
1962
A study of parental age effects on the occurrence of fresh mutations for the Apert syndrome
1974
Design and End Points of Clinical Trials for Patients With Progressive Prostate Cancer and Castrate Levels of Testosterone: Recommendations of the Prostate Cancer Clinical Trials Working Group
2008 Standout
Crbn I391V is sufficient to confer in vivo sensitivity to thalidomide and its derivatives in mice
2018
Apoptotic signaling induced by immunomodulatory thalidomide analogs in human multiple myeloma cells: therapeutic implications
2002 Standout
(R)- and (S)-3-Fluorothalidomides: Isosteric Analogues of Thalidomide
1999
Mutations in the NSDHL gene, encoding a 3?-hydroxysteroid dehydrogenase, cause CHILD syndrome
2000
The Fetal Alcohol Syndrome
1978 Standout
Long-Run Health Impacts of Income Shocks: Wine and Phylloxera in Nineteenth-Century France
2010 StandoutNobel
Cleft palate in mice with a targeted mutation in the γ-aminobutyric acid-producing enzyme glutamic acid decarboxylase 67
1997 StandoutNobel
Works of W. Lenz being referenced
Smoking during pregnancy and congenital limb deficiency
1994
Fraser syndrome (cryptophthalmos with syndactyly) in the fetus and newborn
1990
A short history of thalidomide embryopathy
1988
[Thalidomide embryopathy in Japan].
1968
Polysyndaktylie, verk�rzte Gliedma�en und Genitalfehlbildungen: Kennzeichen eines selbst�ndigen Syndroms?
1971
Malformations Caused by Drugs in Pregnancy
1966
Die Thalidomid-Embryopathie*
1962
Striation of bones in focal dermal hypoplasia: manifestation of functional mosaicism?
1977
Distal limb deficiency following chorionic villus sampling?
1992
Syndrome of Caudal Regression in Infants of Diabetic Mothers: Observations of Further Cases
1966
MULTIPLE CONGENITAL ABNORMALITIES
1962
[Polysyndactyly, short limbs, and genital malformations--a new syndrome?].
1971
THALIDOMIDE AND CONGENITAL ABNORMALITIES
1962
The CHILD syndrome
1980
Phenocopies.
1973
EPIDEMIOLOGY OF CONGENITAL MALFORMATIONS
1965
[On the genetics of incontinentia pigmenti].
1961
Das erbliche Syndrom: Innenohrschwerhörigkeit und Jodfehlverwertung mit Kropf1
1961
Phenocopy
1970
THALIDOMIDE AND CONGENITAL ABNORMALITIES
1962
Zur h�ufigkeit und Mutationsrate des Apert-Syndroms
1967
An epidemiological study of isolated split hand/foot in Hungary, 1975-1984.
1993
Median cleft face syndrome in association with hydrocephalus, agenesis of the corpus callosum, holoprosencephaly and choanal atresia
1987