Citation Impact
Citing Papers
PDGFRA Activating Mutations in Gastrointestinal Stromal Tumors
2003 StandoutScience
Dishevelled 2 Recruits ß-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4
2003 StandoutScienceNobel
Keeping G Proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and Gßγ
2003 StandoutScienceNobel
Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels
2006 StandoutNobel
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
2010 StandoutNobel
The Dual Role of TGFβ in Human Cancer: From Tumor Suppression to Cancer Metastasis
2012
Concordant Regulation of Gene Expression by Hypoxia and 2-Oxoglutarate-dependent Dioxygenase Inhibition
2006 StandoutNobel
Loss of Hypoxia-Inducible Factor Prolyl Hydroxylase Activity in Cardiomyocytes Phenocopies Ischemic Cardiomyopathy
2010 StandoutNobel
β-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation
2009 StandoutNobel
A new and recurrent activating length mutation in exon 20 of the FLT3 gene in acute myeloid leukemia
2002
Mislocalized Activation of Oncogenic RTKs Switches Downstream Signaling Outcomes
2009
Stromal fibroblasts in cancer initiation and progression
2004 StandoutNature
The role of FLT3 in haematopoietic malignancies
2003
MYC on the Path to Cancer
2012 Standout
A view on drug resistance in cancer
2019 StandoutNature
Structural basis of the Axin–adenomatous polyposis coli interaction
2000
The contribution of VHL substrate binding and HIF1-α to the phenotype of VHL loss in renal cell carcinoma
2002
Targeting HIF-1 for cancer therapy
2003 StandoutNobel
Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus
2003 Standout
On-target Inhibition of Tumor Fermentative Glycolysis as Visualized by Hyperpolarized Pyruvate
2011
The Structural Basis for Autoinhibition of FLT3 by the Juxtamembrane Domain
2004
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Activation of tyrosine kinases by mutation of the gatekeeper threonine
2008
Upregulation of RGS7 may contribute to tumor necrosis factor-induced changes in central nervous function
1999
TGF-β signaling in tumor suppression and cancer progression
2001 Standout
Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors
2002
Actions of TGF-β as tumor suppressor and pro-metastatic factor in human cancer
2006
Hypoxia and Inflammation
2011 Standout
Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
2015 StandoutNature
HIF2α cooperates with RAS to promote lung tumorigenesis in mice
2009 StandoutNobel
Erythropoietin stimulates proliferation of human renal carcinoma cells
2000
Smad-dependent and Smad-independent pathways in TGF-β family signalling
2003 StandoutNature
The von Hippel-Lindau Gene, Kidney Cancer, and Oxygen Sensing
2003 StandoutNobel
Sunitinib versus Interferon Alfa in Metastatic Renal-Cell Carcinoma
2007 Standout
The C-terminal cytoplasmic Lys-Thr-X-X-X-Trp motif in frizzled receptors mediates Wnt/beta-catenin signalling
2000
Mechanically Activated Ion Channels
2015 StandoutNobel
Single Cell Profiling of Potentiated Phospho-Protein Networks in Cancer Cells
2004
TGF- β signaling in cancer – a double-edged sword
2001
Regulation of angiogenesis by hypoxia: role of the HIF system
2003 StandoutNobel
HIF hydroxylation and the mammalian oxygen-sensing pathway
2003 StandoutNobel
TRP channels as cellular sensors
2003 StandoutNature
Interaction with Podocin Facilitates Nephrin Signaling
2001
The ciliary flow sensor and polycystic kidney disease
2013
Mechanism and function of signal transduction by the Wnt/β-catenin and Wnt/Ca2+ pathways
1999
Sorafenib in Advanced Clear-Cell Renal-Cell Carcinoma
2007 Standout
Treatment of Advanced Renal Cell Carcinoma with the Combination Bevacizumab/Erlotinib/Imatinib: A Phase I/II Trial
2007
Regulation of LEF-1/TCF transcription factors by Wnt and other signals
1999
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
2017 Standout
TGFβ in Cancer
2008 Standout
Wnt/β-Catenin Signaling in Development and Disease
2006 Standout
A Role for the Segment Polarity Gene shaggy/GSK-3 in the Drosophila Circadian Clock
2001 StandoutNobel
Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia
2013 Standout
The von Hippel–Lindau protein, HIF hydroxylation, and oxygen sensing
2005 StandoutNobel
The basics of epithelial-mesenchymal transition
2009 Standout
Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
2008 StandoutNobel
Peripheral TGF-β1 Signaling Is a Critical Event in Bone Cancer-Induced Hyperalgesia in Rodents
2013
Wnt signalling in stem cells and cancer
2005 StandoutNature
VEGF in Signaling and Disease: Beyond Discovery and Development
2019 Standout
Anemia of Chronic Disease
2005 Standout
Functional Characterization of FLT3 Receptor Signaling Deregulation in Acute Myeloid Leukemia by Single Cell Network Profiling (SCNP)
2010
LDH-A inhibition, a therapeutic strategy for treatment of hereditary leiomyomatosis and renal cell cancer
2009
β-Arrestin2 mediates the initiation and progression of myeloid leukemia
2012 StandoutNobel
Treatment of Metastatic Renal Cell Carcinoma With a Combination of Bevacizumab and Erlotinib
2005
Metal Catalysts for Heterogeneous Catalysis: From Single Atoms to Nanoclusters and Nanoparticles
2018 Standout
Activation of Wnt signalling in acute myeloid leukemia by induction of Frizzled-4
1992
Translocation Products in Acute Myeloid Leukemia Activate the Wnt Signaling Pathway in Hematopoietic Cells
2004
Covalent Chemistry beyond Molecules
2016 StandoutNobel
von Hippel-Lindau Disease
2006 StandoutNobel
HIF hydroxylation and the mammalian oxygen-sensing pathway
2003 StandoutNobel
Regulator of G Protein Signaling Proteins: Novel Multifunctional Drug Targets
2001
Pain regulation by non-neuronal cells and inflammation
2016 StandoutScience
Extreme hydrops fetalis and cardiovascular abnormalities in mice lacking a functional Adrenomedullin gene
2001 StandoutNobel
Cardiovascular, skeletal, and renal defects in mice with a targeted disruption of the Pkd1 gene
2001
Inhibition of Adipogenesis by Wnt Signaling
2000 StandoutScience
Polycystin 1 is required for the structural integrity of blood vessels
2000
Kinase requirements in human cells: III. Altered kinase requirements inVHL−/− cancer cells detected in a pilot synthetic lethal screen
2008 StandoutNobel
Single-Site Palladium(II) Catalyst for Oxidative Heck Reaction: Catalytic Performance and Kinetic Investigations
2015
Polycystins and partners: proposed role in mechanosensitivity
2014
Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum
2011 StandoutScience
Bipyridine- and Phenanthroline-Based Metal–Organic Frameworks for Highly Efficient and Tandem Catalytic Organic Transformations via Directed C–H Activation
2015
SU11248 is a novel FLT3 tyrosine kinase inhibitor with potent activity in vitro and in vivo
2003
FLT3 expressing leukemias are selectively sensitive to inhibitors of the molecular chaperone heat shock protein 90 through destabilization of signal transduction-associated kinases.
2003
The von Hippel-Lindau Tumor Suppressor Protein and Clear Cell Renal Carcinoma
2007 StandoutNobel
Casein kinase Iɛ in the Wnt pathway: Regulation of β-catenin function
1999
Heterogeneous catalytic approaches in C–H activation reactions
2016
GENETICS OF MYELOID LEUKEMIAS
2002
TGF-β Promotes the Establishment of Renal Cell Carcinoma Bone Metastasis
2006
Dual Role of Transforming Growth Factor β in Mammary Tumorigenesis and Metastatic Progression
2005
Role ofVHLGene Mutation in Human Cancer
2004 StandoutNobel
The FLT3 Internal Tandem Duplication Mutation Prevents Apoptosis in Interleukin-3-Deprived BaF3 Cells Due to Protein Kinase A and Ribosomal S6 Kinase 1–Mediated BAD Phosphorylation at Serine 112
2005
The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease
2006 StandoutScience
Works of W Grüning being referenced
The Polycystic Kidney Disease 1 Gene Product Mediates Protein Kinase C α-dependent and c-Jun N-terminal Kinase-dependent Activation of the Transcription Factor AP-1
1998
The Polycystic Kidney Disease 1 Gene Product Modulates Wnt Signaling
1999
Wnt signaling and transcriptional control of Siamois in Xenopus embryos
1998
Flt3 mutations from patients with acute myeloid leukemia induce transformation of 32D cells mediated by the Ras and STAT5 pathways
2000
Bipyridine Periodic Mesoporous Organosilica: A Solid Ligand for the Iridium‐Catalyzed Borylation of CH Bonds
2014
Modulation of renal tubular cell function by RGS3
1999
Flt3 mutations from patients with acute myeloid leukemia induce transformation of 32D cells mediated by the Ras and STAT5 pathways
2000
Transforming growth factor beta1 is a target for the von Hippel-Lindau tumor suppressor and a critical growth factor for clear cell renal carcinoma.
1999