Citation Impact
Citing Papers
Olefin Cyclopropanation via Carbene Transfer Catalyzed by Engineered Cytochrome P450 Enzymes
2012 StandoutScienceNobel
2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer
2015 Standout
Diterpenes from European Euphorbia Species Serving as Prototypes for Natural‐Product‐Based Drug Discovery
2012
Four diterpene esters from Euphorbia myrsinites
1995
Sense and specificity: a molecular identity for nociceptors
1999 StandoutNobel
A novel agonist, phorbol 12-phenylacetate 13-acetate 20-homovanillate, abolishes positive cooperativity of binding by the vanilloid receptor
1996
Follicular-Patterned Lesions of the Thyroid
2002
Diterpenoid (poly)esters and a ring A-seco-phorboid from the aerial parts of Euphorbia macroclada Boiss
2010
Apoptosis induction and modulation of P-glycoprotein mediated multidrug resistance by new macrocyclic lathyrane-type diterpenoids
2006
Mechanisms and Therapeutic Potential of Vanilloids (Capsaicin-like Molecules)
1993
The capsaicin receptor: a heat-activated ion channel in the pain pathway
1997 StandoutNatureNobel
Biological assays for irritant, tumor-initiating and -promoting activities
1991
ThermoTRP channels and beyond: mechanisms of temperature sensation
2003 StandoutNobel
Marine natural products
1990 Standout
Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide
1999 StandoutNatureNobel
Resiniferatoxin, a phorbol-related diterpene, acts as an ultrapotent analog of capsaicin, the irritant constituent in red pepper
1989 Standout
Existence of slow-cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: Implications on epithelial stem cells
1989 Standout
A Bivalent Tarantula Toxin Activates the Capsaicin Receptor, TRPV1, by Targeting the Outer Pore Domain
2010 StandoutNobel
[3H]resiniferatoxin binding by the vanilloid receptor: species-related differences, effects of temperature and sulfhydryl reagents
1993
The vanilloid (capsaicin) receptor: Receptor types and species differences
1994
The Cloned Capsaicin Receptor Integrates Multiple Pain-Producing Stimuli
1998 StandoutNobel
Comments on Recent Achievements in Biomimetic Organic Synthesis
2003
New 19-acetoxyingol diterpenes from the latex of Euphorbia poisonii (Euphorbiaceae)
1996
Lathyrane diterpenes from Euphorbia prolifera and their inhibitory activities on LPS-induced NO production
2012
Lathyrane diterpenes from Euphorbia lathyris as modulators of multidrug resistance and their crystal structures
2009
Heme Oxygenase-1/Carbon Monoxide: From Basic Science to Therapeutic Applications
2006 Standout
Natural products from true mangrove flora: source, chemistry and bioactivities
2008
Unsaturated Long-Chain N-Acyl-vanillyl-amides (N-AVAMs): Vanilloid Receptor Ligands That Inhibit Anandamide-Facilitated Transport and Bind to CB1 Cannabinoid Receptors
1999 StandoutNobel
Natural products to drugs: natural product-derived compounds in clinical trials
2008 Standout
TNF-α inhibitory diterpenoids from the Chinese mangrove plant Excoecaria agallocha L.
2010
Conformational studies on resiniferatoxin (RTX), an ultrapotent vanilloid agonist
1998
A non‐pungent triprenyl phenol of fungal origin, scutigeral, stimulates rat dorsal root ganglion neurons via interaction at vanilloid receptors
1999
Extracellular Signal-Regulated Kinase and c-Jun NH2-Terminal Kinase Activities Are Continuously and Differentially Increased in Aorta of Hypertensive Rats
1997 StandoutNobel
TRPV1 structures in distinct conformations reveal activation mechanisms
2013 StandoutNatureNobel
Natural Product Hybrids as New Leads for Drug Discovery
2003 Standout
New myrsinol diterpenes from Euphorbia prolifera and their inhibitory activities on LPS-induced NO production
2012
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
2016 StandoutNatureNobel
Cascade Reactions in Total Synthesis
2006 Standout
Effects of the capsaicin analogue resiniferatoxin on spinal nociceptive mechanisms in the rat: behavioral, electrophysiological and in situ hybridization studies
1997
Daphnane diterpenoids isolated from Trigonostemon thyrsoideum as HIV-1 antivirals
2010
Jatrophane and lathyrane diterpenoids from Euphorbia hyberna L.
2002
Molecular Basis for Species-Specific Sensitivity to “Hot” Chili Peppers
2002 StandoutNobel
Duration of desensitization and ultrastructural changes in dorsal root ganglia in rats treated with resiniferatoxin, an ultrapotent capsaicin analog
1989
Vascular protein kinase C in Wistar-Kyoto and spontaneously hypertensive rats
1992
Four new myrsinol diterpenes from Euphorbia prolifera
2012
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
2004 StandoutNatureNobel
Natural products to drugs: natural product derived compounds in clinical trials
2005
A serine-substituted P450 catalyzes highly efficient carbene transfer to olefins in vivo
2013 StandoutNobel
Thermoregulatory effects of resiniferatoxin in the mouse: Comparison with capsaicin
1989
Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia
2000 StandoutNature
Resiniferatoxin and its analogs provide novel insights into the pharmacology of the vanilloid (capsaicin) receptor
1990
The Super-Cooling Agent Icilin Reveals a Mechanism of Coincidence Detection by a Temperature-Sensitive TRP Channel
2004 StandoutNobel
Ingenane diterpenoids from Euphorbia esula
2007
Phytoalexins: Enzymology and Molecular Biology
1983
Total Synthesis of Ingenol
2005
Two pentacyclic diterpene esters from Euphorbia decipiens
1998
Synthetic Studies toward Jatrophane Diterpenes from Euphorbia characias. Enantioselective Synthesis of (−)-15-O-Acetyl-3-O-propionyl-17-norcharaciol
2009
Guidelines for the Early Management of Patients With Acute Ischemic Stroke
2013 Standout
3d Transition Metals for C–H Activation
2018 Standout
Similarities and Differences in the Structure−Activity Relationships of Capsaicin and Resiniferatoxin Analogues
1996
Diterpenoids from Euphorbia micractina
1992
Physiological Implications of Hydrogen Sulfide: A Whiff Exploration That Blossomed
2012 Standout
Diterpene esters from ‘Euphorbium’ and their irritant and cocarcinogenic activity
1974
An Expeditious Procedure for the Isolation of Ingenol from the Seeds of Euphorbia lathyris
1998
Cocarcinogenesis and tumor promoters of the diterpene Ester type as possible carcinogenic risk factors
1981
Diterpenes from Euphorbia segetalis
1998
Tumour promoter TPA enhances transformation of human leukocytes by Epstein–Barr virus
1979 StandoutNatureNobel
Apoprotein E is synthesized and secreted by resident and thioglycollate-elicited macrophages but not by pyran copolymer- or bacillus Calmette-Guerin-activated macrophages.
1983
Chemical composition, toxic/antimetabolic constituents, and effects of different treatments on their levels, in four provenances of L. from Mexico
2005
Paralinones A and B, novel diterpene esters from Euphorbia paralias
1997
Unnatural Natural Products from the Transannular Cyclization of Lathyrane Diterpenes
2001
Calcium regulation of growth and differentiation of mouse epidermal cells in culture
1980 Standout
Regeneration and the mechanism of epidermal tumor promotion
1985
The chemistry of zerumbone. Part 5: Structural transformation of the dimethylamine derivatives
2003 StandoutNobel
Total Synthesis of Ingenol
2003
New tri- and tetracyclic diterpenes from Euphorbia villosa
2004
The biosynthesis of tigliane and related diterpenoids; an intriguing problem
1987
An Asymmetric Synthesis of Aza Analogues of the Tricyclic Skeleton of Daphnane and the ABC Ring System of Phorbol
2002
Differential Activation and Desensitization of Sensory Neurons by Resiniferatoxin
1997
Different biological targets for resiniferatoxin and phorbol 12-myristate 13-acetate.
1980
Specific binding of phorbol ester tumor promoters
1980 Standout
A Novel Lathyrane Diterpenoid from the Roots of Euphorbia lathyris
1998
Diterpenes from euphorbia seguieriana
1995
Differential inducibility of Epstein‐Barr virus in cloned, non‐producer raji cells
1979 StandoutNobel
Jatrophane and lathyrane diterpenoid esters from north american leafy spurge seed
1992
A Tetracyclic diterpene and triterpenes from euphorbia segetalis
1998
Lathyrane Diterpenoids from the Roots of Euphorbia micractina and Their Biological Activities
2011
A New P-Glycoprotein Inhibitor from the Caper Spurge (Euphorbia lathyris)
2002
Cooperative Reactivity in an Extended-Viologen-Based Cyclophane
2016 StandoutNobel
Selectivity of ruthenium red in inhibiting bronchoconstriction and CGRP release induced by afferent C‐fibre activation in the guinea‐pig lung
1991
Diterpenoids from Euphorbia esula
2010
Diterpenoids from Euphorbia pithyusa subsp. cupanii
1999
Lathyranone A: A Diterpenoid Possessing an Unprecedented Skeleton from Euphorbia lathyris
2007
Impaired Nociception and Pain Sensation in Mice Lacking the Capsaicin Receptor
2000 StandoutScienceNobel
Differential inhibition of epstein‐barr virus induction by the amino acid analogue, L‐canavanine
1980 StandoutNobel
Investigations into the skin-irritant properties of resiniferonol ortho esters
1979
Vanilloid (Capsaicin) Receptors and Mechanisms
1999 Standout
Resiniferatoxin Binds to the Capsaicin Receptor (TRPV1) near the Extracellular Side of the S4 Transmembrane Domain
2004
Wickerols A and B: novel anti-influenza virus diterpenes produced by Trichoderma atroviride FKI-3849
2012 StandoutNobel
Plant Products as Antimicrobial Agents
1999 Standout
Biomimetische organische Synthesen: Anmerkungen zu jüngeren Ergebnissen
2003
Enzymatic Chemistry of Cyclopropane, Epoxide, and Aziridine Biosynthesis
2011
Enzymatic construction of highly strained carbocycles
2018 StandoutScienceNobel
Dissociation of tumor promoter-stimulated ornithine decarboxylase activity and DNA synthesis in mouse epidermis in vivo and in vitro by fluocinolone acetonide, a tumor-promotion inhibitor.
1977
Prediction of stroke outcome with echoplanar perfusion- and diffusion-weighted MRI
1998
Characterization of the Interaction of Ingenol 3-Angelate with Protein Kinase C
2004
Jatropha curcas L. as a source for the production of biofuel in Nicaragua
1996
Dietary Carcinogens and Anticarcinogens
1983 StandoutScience
Apolipoprotein E: Cholesterol Transport Protein with Expanding Role in Cell Biology
1988 StandoutScience
Selectively Cytotoxic Diterpenes from Euphorbia poisonii
1996
Specific vanilloid responses in C6 rat glioma cells
1998
Chemical and Pharmacological Research of the Plants in Genus Euphorbia
2008 Standout
Highly irritant ingenane type diterpene esters fromEuphorbia cyparissias L.
1981
Cyclizations of N-Acyliminium Ions
2004 Standout
New Jatrophane Diterpenoid Esters from Euphorbia turczaninowii
2001
Review of biodiesel composition, properties, and specifications
2011 Standout
The Vanilloid Receptor: A Molecular Gateway to the Pain Pathway
2001 StandoutNobel
Isolation and Structure Revision of Pepluane Diterpenoids from Euphorbia peplus
1998
Diterpenoids from Euphorbia micractina
1995
Biosynthesis and Metabolism of Cyclopropane Rings in Natural Compounds
2003
Increase in the synthesis of a Mr 32,000 protein in BALB/c 3T3 cells treated with tumor-promoting indole alkaloids or polyacetates.
1983
Lathyranoic Acid A: First Secolathyrane Diterpenoid in Nature fromEuphorbia lathyris
2005
Pentacyclic diterpene esters from Euphorbia aleppica
1995
A New Approach for Ingenol Synthesis
1997
Nonpolar Components of the Latex of Euphorbia peplus
2000
Characterization of Functional Vanilloid Receptors Expressed by Mast Cells
1998
Tumour promoters of the irritant diterpene ester type as risk factors of cancer in man
1987
Euphorbia Diterpenes: Isolation, Structure, Biological Activity, and Synthesis (2008–2012)
2014 Standout
Approach to the Tricyclic Core of the Tigliane–Daphnane Diterpenes. Concerning the Utility of Transannular Aldol Additions
2013
Navigating the Chiral Pool in the Total Synthesis of Complex Terpene Natural Products
2017
Transition Metal-Catalyzed C–H Amination: Scope, Mechanism, and Applications
2017 Standout
Thiourea analogues of resiniferatoxin as ligands for the vanilloid receptor
1995
Photochemical Approaches to Complex Chemotypes: Applications in Natural Product Synthesis
2016
A new lathyrane diterpene glycoside from Euphorbia helioscopia L.
2009
Strong and Confined Acids Enable a Catalytic Asymmetric Nazarov Cyclization of Simple Divinyl Ketones
2019 StandoutNobel
Diterpenes and phloracetophenones from Euphorbia portulacoides
1996
Properties of a Resiniferatoxin-stimulated, Calcium Inhibited but Phosphatidylserine-dependent Kinase, which is Distinct from Protein Kinase C Isotypes α, β1γ, δ, ε and η
1995
13C-NMR Data of Three Important Diterpenes Isolated from Euphorbia Species
2009
Three new diterpene esters from Euphorbia decipiens
1998
Transannular cyclizations of zerumbone epoxide
1982
Ingenane and lathyrane diterpenes from the latex of Euphorbia canariensis
1997
Recent Advances in the Baylis−Hillman Reaction and Applications
2003 Standout
Neurogenic component of phorbol ester-induced mouse skin inflammation.
1989
Synthesis of 2,9,10-trioxatricyclo[4.3.1.0]decane analogues of resiniferatoxin
1992
Synthetic approaches to ingenol
2005
Ingenane and lathyrane diterpenes from the latex of euphorbia acrurensis
1998
8-methoxyingol esters from the latex of Euphorbia hermentiana
1983
Works of W. Adolf being referenced
Oligo- and macrocyclic diterpenes in Thymelaeaceae and Euphorbiaceae occurring and utilized in Yunnan (southwest China)
1993
Biosynthesis of the Diterpene Phytoalexin Casbene
1978
Irritant Principles of the Mezereon Family (Thymelaeaceae), V. New Skin Irritants and Tumor Promoters of the Daphnane and 1α-Alkyldaphnane Type from Synaptolepis kirkii and Synaptolepis retusa
1988
On the active principles of the spurge family
1975
1983
New irritant diterpene-esters from roots of L. (Euphorbiaceae)
1980
Inhibition of specific binding of [3H]phorbol-12,13-dipropionate to an epidermal fraction by certain irritants and irritant promoters of mouse skin
1983
[The importance of atypical adenoma of the thyroid gland].
1988
Irritant phorbol derivatives from four Jatropha species
1984
“Euphorbiasteroid” (Epoxy-lathyrol) A new tricyclic diterpene from L.
1970
Biological assays for irritant tumor-initiating and -promoting activities
1982
Structure determination of the new tetracyclic diterpene ingenol-triacetate with triple product methods
1970
Irritant diterpene ester promoters of mouse skin: contributions to etiologies of environmental cancer and to biochemical mechanisms of carcinogenesis.
1983
Investigations of Medicinal Plants of Euphorbiaceae and Thymelaeaceae Occurring and Used in Thailand; II. Cryptic Irritants of the Diterpene Ester Type from ThreeExcoecaria species
1985
Resiniferatoxin and other esters of novel polyfuncticnal diterpenes from Euphorbia resinifera and unispina
1975
New tigliane and daphnane derivatives fromPimelea prostrata andPimelea simplex
1977
Oligo‐ and macrocyclic diterpenes in thymelaeaceae and euphorbiaceae occurring and utilized in Yunnan (Southwest China). 2. Ingenane type diterpene esters from Euphorbia nematocypha Hand.‐Mazz
1992
Further new diterpene esters from the irritant and cocarcinogenic seed oil and latex of the caper spurge (Euphorbia lathyris L.)
1971
Röntgenstrukturanalyse eines neuen makrozyklischen diterpenesters aus der springwolfsmilch (Euphorbia Lathyris L.)
1970
On the Active Principles of the Euphorbiaceae, IXa Ingenane Type Diterpene Esters from Five Euphorbia Species
1984
Structure-activity Relations of Polyfunctional Diterpenes of the Daphnane Type. I. Revised Structure For Resiniferatoxin and Structure-activity Relations of Resini-feronol and Some of its Esters
1982
On the irritant and cocarcinogenic principles of hippomane mancinella.
1975
On the irritant and cocarcinogenic principles of hippomane mancinella
1975
Lathyrane type diterpene esters from Euphorbia lathyris
1984
Diterpenoid Irritants and Cocarcinogens in Euphorbiaceae and Thymelaeaceae: Structural Relationships in View of their Biogenesis
1977
Systemic promoting action and leukemogenesis in SWR mice by phorbol and structurally related polyfunctional diterpenes
1979
Tumor-Promoting Diterpene Esters Prevent Macrophage Activation and Suppress Macrophage Tumoricidal Capacity
1982
Zur Chemie des Ingenols, I Ingenol und einige seiner Derivate/ On the Chemistry of Ingenol, I Ingenol and Some of its Derivatives
1981
Structure of 7-hydroxy-lathyrol a further diterpene from euphorbia lathyris L.
1971
On the Active Principles of the Spurge Family, X. 1,2Skin Irritants, Cocarcinogens, and Cryptic Cocarcinogens from the Latex of the Manchineel Tree
1984
New highly irritant 1-alkyldaphnane derivatives from several species of thymelaeaceae
1977
Macrocyclic Lathyrane Type Diterpene Esters (Jolkinols) from Callus Cultures and Roots ofEuphorbia lathyris
1984