Citation Impact
Citing Papers
The mevalonate pathway regulates microRNA activity in Caenorhabditis elegans
2012 StandoutNobel
Developmental Decline in Neuronal Regeneration by the Progressive Change of Two Intrinsic Timers
2013 StandoutScienceNobel
Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
2003 Standout
Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
2002 Standout
Regulation of Intracellular Accumulation of Mutant Huntingtin by Beclin 1
2006
Hallmarks of Cancer: The Next Generation
2011 Standout
Common defects of different retinoic acid resistant promyelocytic leukemia cells are persistent telomerase activity and nuclear body disorganization
1997
Testicular Germ-Cell Cancer
1997 Standout
Identification of a novel nuclear pore-associated protein as a functional target of the HIV-1 Rev protein in yeast
1995 StandoutNobel
Retinoic acid receptors: From molecular mechanisms to cancer therapy
2014
Transcriptional regulator of programmed cell death encoded by Caenorhabditis elegans gene ces-2
1996 StandoutNatureNobel
MicroRNAs
2004 Standout
A novel repeat domain that is often associated with RING finger and B-box motifs
1998 StandoutNobel
Crystal Structure of the Bcl-XL-Beclin 1 Peptide Complex
2007
The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
1997 StandoutNatureNobel
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
2003 StandoutNobel
The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR
1991
Cytoscape: A Software Environment for Integrated Models of Biomolecular Interaction Networks
2003 Standout
Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG
2006 Standout
Gene expression–based high-throughput screening(GE-HTS) and application to leukemia differentiation
2004
nhl-2 Modulates MicroRNA Activity in Caenorhabditis elegans
2009 StandoutNobel
Autophagy as a cell death and tumor suppressor mechanism
2004 Standout
Eaten alive: a history of macroautophagy
2010 Standout
Deletion analysis of chromosome 13q14.3 and characterisation of an alternative splice form of LEU1 in B cell chronic lymphocytic leukemia
2002
Proto-oncogene PML controls genes devoted to MHC class I antigen presentation
1998 Nature
Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA
2000 StandoutNatureNobel
The RING Finger
1993
IκBγ, a 70 kd protein identical to the C-terminal half of p110 NF-κB: A new member of the IκB family
1992
Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation
1990 StandoutNatureNobel
The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene
1992
Role of autophagy in cancer
2007 Standout
The Oncogenic Cysteine-rich LIM domain protein Rbtn2 is essential for erythroid development
1994 StandoutNobel
Comprehensive analysis of a large genomic sequence at the putative B-cell chronic lymphocytic leukaemia (B-CLL) tumour suppresser gene locus
2001
Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis
2007
Enhancement of Memory-Related Long-Term Facilitation by ApAF, a Novel Transcription Factor that Acts Downstream from Both CREB1 and CREB2
2000 StandoutNobel
The Bloom's syndrome gene product is homologous to RecQ helicases
1995
Translocations, master genes, and differences between the origins of acute and chronic leukemias
1991
The autophagosomal–lysosomal compartment in programmed cell death
2001
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
Physiological functions of Atg6/Beclin 1: a unique autophagy-related protein
2007
MicroRNA Pathways in Flies and Worms
2003 StandoutNobel
Genes and Mechanisms Related to RNA Interference Regulate Expression of the Small Temporal RNAs that Control C. elegans Developmental Timing
2001 StandoutNobel
Development by Self-Digestion
2004 Standout
Tumor suppressors and cell metabolism: a recipe for cancer growth
2009
Induction of autophagy and inhibition of tumorigenesis by beclin 1
1999 StandoutNature
Autophagy suppresses tumor progression by limiting chromosomal instability
2007
Hepatitis B virus X protein sensitizes cells to starvation‐induced autophagy via up‐regulation of beclin 1 expression†‡
2008
Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis
2007
Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx
1995 StandoutNobel
New microRNAs from mouse and human
2003
Lysosomes and autophagy in cell death control
2005
DRAM, a p53-Induced Modulator of Autophagy, Is Critical for Apoptosis
2006
The lin-41 RBCC Gene Acts in the C. elegans Heterochronic Pathway between the let-7 Regulatory RNA and the LIN-29 Transcription Factor
2000 StandoutNobel
Atg8, a Ubiquitin-like Protein Required for Autophagosome Formation, Mediates Membrane Tethering and Hemifusion
2007 StandoutNobel
Functional Proteomics Reveals the Biochemical Niche of C. elegans DCR-1 in Multiple Small-RNA-Mediated Pathways
2006 StandoutNobel
Autophagy in cell death: an innocent convict?
2005 Standout
MicroRNA expression profiles classify human cancers
2005 StandoutNatureNobel
Autophagic pathways as new targets for cancer drug development
2010
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
The role of autophagy during the early neonatal starvation period
2004 StandoutNatureNobel
Cloning and Characterization of a Novel RING Finger Protein That Interacts with Class V Myosins
1999
Transcriptional activation by the v-myb oncogene and its cellular progenitor, c-myb
1989 StandoutNobel
Endoglin, a TGF-β binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1
1994 Standout
Vitamin D analog EB1089 triggers dramatic lysosomal changes and Beclin 1-mediated autophagic cell death
2005
Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma
2007
microRNAs
2001 StandoutNobel
The functions of animal microRNAs
2004 StandoutNatureNobel
cactus, a gene involved in dorsoventral pattern formation of Drosophila, is related to the IκB gene family of vertebrates
1992 StandoutNobel
The autophagy effector Beclin 1: a novel BH3-only protein
2008
Autophagy Protects the Retina from Light-induced Degeneration
2013
Characterization of the 13q14 tumor suppressor locus in CLL: identification of ALT1, an alternative splice variant of the LEU2 gene.
2001
can, a Putative Oncogene Associated with Myeloid Leukemogenesis, May Be Activated by Fusion of Its 3‣ Half to Different Genes: Characterization of the set Gene
1992
Moloney murine leukemia virus-induced myeloid tumors in adult BALB/c mice: requirement of c-myb activation but lack of v-abl involvement
1987
The coordinate regulation of the p53 and mTOR pathways in cells
2005
Expression of murine interleukin 7 in a murine glioma cell line results in reduced tumorigenicity in vivo.
1992 StandoutNobel
Structure of the STRA6 receptor for retinol uptake
2016 StandoutScienceNobel
The PAX3-FKHR Fusion Protein Created by the t(2;13) Translocation in Alveolar Rhabdomyosarcomas Is A More Potent Transcriptional Activator than PAX3
1995
Role of MicroRNAs in Plant and Animal Development
2003 StandoutScienceNobel
Role of Autophagy in Breast Cancer
2007
The translocation (6;9), associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can mRNA.
1992
Tumor Suppressor Genes
1991 Science
Expression of a hemopoietic growth factor cDNA in a factor-dependent cell line results in autonomous growth and tumorigenicity
1985
Pbx1 is converted into a transcriptional activator upon acquiring the N-terminal region of E2A in pre-B-cell acute lymphoblastoid leukemia.
1993
Membrane proteomics of phagosomes suggests a connection to autophagy
2008 StandoutNobel
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
2003
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways
1998 StandoutNobel
Interpreting patterns of gene expression with self-organizing maps: Methods and application to hematopoietic differentiation
1999 Standout
Use of Chromatin Immunoprecipitation To Clone Novel E2F Target Promoters
2001
The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript.
1993
Functional specificity of the mammalian Beclin-Vps34 PI 3-kinase complex in macroautophagy versus endocytosis and lysosomal enzyme trafficking
2006
Beclin 1 gene inhibits tumor growth in colon cancer cell lines.
2007
The Translocation (6;9), Associated with a Specific Subtype of Acute Myeloid Leukemia, Results in the Fusion of Two Genes, dek and can, and the Expression of a Chimeric, Leukemia-Specific dek-can mRNA
1992
Down-regulation of candidate tumor suppressor genes within chromosome band 13q14.3 is independent of the DNA methylation pattern in B-cell chronic lymphocytic leukemia
2002
Alternative 5′ exons in c-abl mRNA
1986 Nobel
Hlf, a novel hepatic bZIP protein, shows altered DNA-binding properties following fusion to E2A in t(17;19) acute lymphoblastic leukemia.
1992
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
ncl-1 Is Required for the Regulation of Cell Size and Ribosomal RNA Synthesis in Caenorhabditis elegans
1998
Autoproteolysis in nucleoporin biogenesis
1999 StandoutNobel
Two Modes of c-myb Activation in Virus-Induced Mouse Myeloid Tumors
1986
Chromosome Aberrations and Cancer
1991 Science
Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair
2008 StandoutNobel
Two yeast nuclear pore complex proteins involved in mRNA export form a cytoplasmically oriented subcomplex
1998 StandoutNobel
A family of unusually spliced biologically active transcripts encoded by a Drosophila clock gene
1987 StandoutNatureNobel
Identification of many microRNAs that copurify with polyribosomes in mammalian neurons
2003 StandoutNobel
The Double-Edged Sword of Autophagy Modulation in Cancer
2009
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
Autophagy: Basic Principles and Relevance to Disease
2008
Accelerated degradation of PML-retinoic acid receptor alpha (PML-RARA) oncoprotein by all-trans-retinoic acid in acute promyelocytic leukemia: possible role of the proteasome pathway.
1996 StandoutNobel
Activation of fibroblasts in cancer stroma
2010
Caenorhabditis elegans microRNAs of the let-7 family act in innate immune response circuits and confer robust developmental timing against pathogen stress
2015 StandoutNobel
Beclin 1 contains a leucine-rich nuclear export signal that is required for its autophagy and tumor suppressor function.
2001
Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes: characterization of the set gene.
1992
Works of V.V.V.S. Murty being referenced
Confirmation of 15q26.1 as the site of the FES protooncogene by fluorescence in situ hybridization
1993
The gene for fibroblast activation protein α (FAP), a putative cell surface-bound serine protease expressed in cancer stroma and wound healing, maps to chromosome band 2q23
1995
Cloning and Genomic Organization of Beclin 1, a Candidate Tumor Suppressor Gene on Chromosome 17q21
1999
Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML
1991
Transforming Growth Factor Receptor Gene TGFBR2 Maps to Human Chromosome Band 3p22
1994
Nucleotide sequence, transcription map, and mutation analysis of the 13q14 chromosomal region deleted in B-cell chronic lymphocytic leukemia
2001
Allelic deletions in the long arm of chromosome 12 identify sites of candidate tumor suppressor genes in male germ cell tumors.
1992
Friend murine leukemia virus-immortalized myeloid cells are converted into tumorigenic cell lines by Abelson leukemia virus.
1985
Allelic loss and somatic differentiation in human male germ cell tumors.
1994