Standout Papers
Citation Impact
Citing Papers
Alternative Zippering as an On-Off Switch for SNARE-Mediated Fusion
2009 StandoutScienceNobel
Distinct Kinetic Changes in Neurotransmitter Release After SNARE Protein Cleavage
2005 ScienceNobel
Complexin Controls the Force Transfer from SNARE Complexes to Membranes in Fusion
2009 StandoutScienceNobel
Single Reconstituted Neuronal SNARE Complexes Zipper in Three Distinct Stages
2012 StandoutScienceNobel
SNARE Proteins: One to Fuse and Three to Keep the Nascent Fusion Pore Open
2012 StandoutScienceNobel
SNARE Function Analyzed in Synaptobrevin/VAMP Knockout Mice
2001 StandoutScienceNobel
SNARE-complex disassembly by NSF follows synaptic-vesicle fusion
2001
Conformational Switch of Syntaxin-1 Controls Synaptic Vesicle Fusion
2008 StandoutScienceNobel
α-Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro
2010 StandoutScienceNobel
Fusion of Cells by Flipped SNAREs
2003 StandoutScienceNobel
A Genomewide Search for Ribozymes Reveals an HDV-Like Sequence in the Human CPEB3 Gene
2006 StandoutScienceNobel
Functional architecture of an intracellular membrane t-SNARE
2000 StandoutNatureNobel
Synaptotagmin I: A major Ca2+ sensor for transmitter release at a central synapse
1994 StandoutNobel
Temperature-Sensitive Paralytic Mutations Demonstrate that Synaptic Exocytosis Requires SNARE Complex Assembly and Disassembly
1998
COPII-Coated Vesicle Formation Reconstituted with Purified Coat Proteins and Chemically Defined Liposomes
1998 StandoutNobel
SNARE complexes and neuroexocytosis: how many, how close?
2005
Syntaxin and synaptobrevin function downstream of vesicle docking in drosophila
1995
Sec18p (NSF)-Driven Release of Sec17p (α-SNAP) Can Precede Docking and Fusion of Yeast Vacuoles
1996
SNARE Complex Oligomerization by Synaphin/Complexin Is Essential for Synaptic Vesicle Exocytosis
2001
The X-ray crystal structure of neuronal Sec1 from squid sheds new light on the role of this protein in exocytosis
2000
Ca2+-Dependent Synaptotagmin Binding to SNAP-25 Is Essential for Ca2+-Triggered Exocytosis
2002
SNAREs and SNARE regulators in membrane fusion and exocytosis
1999
Calcium Can Disrupt the SNARE Protein Complex on Sea Urchin Egg Secretory Vesicles without Irreversibly Blocking Fusion
1998
Isolation and Biochemical Characterization of a Ca2+-independent α-Latrotoxin-binding Protein
1996
Membrane Tethering and Fusion in the Secretory and Endocytic Pathways
2000
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Functional and physical coupling of voltage‐sensitive calcium channels with exocytotic proteins: ramifications for the secretion mechanism
2001
Mixed and Non-cognate SNARE Complexes
1999
α-Latrotoxin and Its Receptors
2007
The C Terminus of SNAP25 Is Essential for Ca2+-dependent Binding of Synaptotagmin to SNARE Complexes
2000
Docked granules, the exocytic burst, and the need for ATP hydrolysis in endocrine cells
1995
N-Ethylmaleimide-sensitive Factor Acts at a Prefusion ATP-dependent Step in Ca2+-activated Exocytosis
1996
Munc18-1 Promotes Large Dense-Core Vesicle Docking
2001 StandoutNobel
-Latrotoxin Stimulates a Novel Pathway of Ca2+-Dependent Synaptic Exocytosis Independent of the Classical Synaptic Fusion Machinery
2009 StandoutNobel
Drosophila CAPS Is an Essential Gene that Regulates Dense-Core Vesicle Release and Synaptic Vesicle Fusion
2001
Activity-dependent changes in partial VAMP complexes during neurotransmitter release
1999
Monitoring of Black Widow Spider Venom (BWSV) induced exo- and endocytosis in living frog motor nerve terminals with FM1-43
1995
α-Latrotoxin Stimulates Exocytosis by the Interaction with a Neuronal G-Protein-Coupled Receptor
1997
Complexins: Cytosolic proteins that regulate SNAP receptor function
1995
Snares and munc18 in synaptic vesicle fusion
2002 StandoutNobel
SNAREs and the specificity of transport vesicle targeting
1995
Physical Link and Functional Coupling of Presynaptic Calcium Channels and the Synaptic Vesicle Docking/Fusion Machinery
1998
Gβγ acts at the C terminus of SNAP-25 to mediate presynaptic inhibition
2005
Docking of Secretory Vesicles Is Syntaxin Dependent
2006
SNAREpins: Minimal Machinery for Membrane Fusion
1998 StandoutNobel
A Structural Change Occurs upon Binding of Syntaxin to SNAP-25
1997
The “quad‐partite” synapse: Microglia‐synapse interactions in the developing and mature CNS
2012
SNAP-25 Is Required for a Late Postdocking Step in Ca2+-dependent Exocytosis
1996
Sequential N‐ to C‐terminal SNARE complex assembly drives priming and fusion of secretory vesicles
2006
The small GTP-binding protein Rab3A regulates a late step in synaptic vesicle fusion
1997 StandoutNatureNobel
Protease Resistance of Syntaxin·SNAP-25·VAMP Complexes
1998
Analysis of regulated exocytosis in adrenal chromaffin cells: insights into NSF/SNAP/SNARE function
1998
The Probability of Quantal Secretion Near a Single Calcium Channel of an Active Zone
2000
Neurotransmission: harnessing fusion machinery at the synapse
1994 StandoutNobel
A Late Phase of Exocytosis from Synaptosomes Induced by Elevated [Ca2+]i Is Not Blocked by Clostridial Neurotoxins
2000
Synaptotagmin I functions as a calcium regulator of release probability
2001 StandoutNatureNobel
Membrane Fusion
2003 StandoutNobel
Compartmental specificity of cellular membrane fusion encoded in SNARE proteins
2000 StandoutNatureNobel
α-Synuclein Cooperates with CSPα in Preventing Neurodegeneration
2005 StandoutNobel
Two functionally distinct α2-adrenergic receptors regulate sympathetic neurotransmission
1999 StandoutNatureNobel
Genetic ablation of the t-SNARE SNAP-25 distinguishes mechanisms of neuroexocytosis
2001
Vesicular restriction of synaptobrevin suggests a role for calcium in membrane fusion
2002 Nature
Ca2+ Regulates the Interaction between Synaptotagmin and Syntaxin 1
1995
Differential Regulation of Synaptic Vesicle Tethering and Docking by UNC-18 and TOM-1
2010
Defects in synaptic vesicle docking in unc-18 mutants
2003
Single Molecule Mechanical Probing of the SNARE Protein Interactions
2006
Neuroligins and neurexins link synaptic function to cognitive disease
2008 StandoutNatureNobel
SNAREs and membrane fusion in the Golgi apparatus
1998
Molecular form follows function: (un)snaring the SNAREs
2008
A dual-Ca2+-sensor model for neurotransmitter release in a central synapse
2007 StandoutNatureNobel
The concept of a calcium sensor in transmitter release
1999
Mutations in the drosophila Rop gene suggest a function in general secretion and synaptic transmission
1994
Interactions of Presynaptic Ca2+ Channels and Snare Proteins in Neurotransmitter Release
1999
Crystal Structure of the Vesicular Transport Protein Sec17
1999
Interactions between Presynaptic Calcium Channels and Proteins Implicated in Synaptic Vesicle Trafficking and Exocytosis
1998
Role of calcium in neurotransmitter release evoked by α-latrotoxin or hypertonic sucrose
2000 StandoutNobel
Systematic analysis of genes required for synapse structure and function
2005 StandoutNatureNobel
Calcium-dependent interaction of N-type calcium channels with the synaptic core complex
1996 Nature
Essential functions of synapsins I and II in synaptic vesicle regulation
1995 StandoutNatureNobel
Syntaxin 1A Interacts with Multiple Exocytic Proteins to Regulate Neurotransmitter Release In Vivo
1999
Microglial Interactions with Synapses Are Modulated by Visual Experience
2010
The role of Rab3A in neurotransmitter release
1994 StandoutNatureNobel
The synaptic vesicle cycle: a cascade of protein–protein interactions
1995 StandoutNatureNobel
Facilitation, augmentation and potentiation at central synapses
2000
A post-docking role for synaptobrevin in synaptic vesicle fusion
1994
α-Neurexins couple Ca2+ channels to synaptic vesicle exocytosis
2003 StandoutNatureNobel
Differential Effects of SNAP-25 Deletion on Ca2+-Dependent and Ca2+-Independent Neurotransmission
2007 StandoutNobel
Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner
2012 Standout
RIM1α forms a protein scaffold for regulating neurotransmitter release at the active zone
2002 StandoutNatureNobel
α-Latrotoxin action probed with recombinant toxin: receptors recruit α-latrotoxin but do not transduce an exocytotic signal
1998 StandoutNobel
Development of Vesicle Pools during Maturation of Hippocampal Synapses
2002
The Tlg SNARE complex is required for TGN homotypic fusion
2001
Expression of Multiple UNC-13 Proteins in theCaenorhabditis elegansNervous System
2000
Postsynaptic Membrane Fusion and Long-Term Potentiation
1998 StandoutScienceNobel
Ordering the Final Events in Yeast Exocytosis
2000
The Core Membrane Fusion Complex Governs the Probability of Synaptic Vesicle Fusion But Not Transmitter Release Kinetics
2002
A VAMP-Binding Protein from Aplysia Required for Neurotransmitter Release
1995 StandoutScienceNobel
Synaptic Physiology and Ultrastructure incomatoseMutants Define anIn VivoRole for NSF in Neurotransmitter Release
1998
Mechanisms of Synaptic Vesicle Exocytosis
2000
Botulinum Neurotoxin a Blocks Synaptic Vesicle Exocytosis but Not Endocytosis at the Nerve Terminal
1999
RIM-Binding Protein, a Central Part of the Active Zone, Is Essential for Neurotransmitter Release
2011 StandoutScienceNobel
GENETICS OF SYNAPTIC VESICLE FUNCTION: Toward the Complete Functional Anatomy of an Organelle
1999 StandoutNobel
Paralysis and Early Death in Cysteine String Protein Mutants of Drosophila
1994 Science
Specificity of Ca2+-Dependent Protein Interactions Mediated by the C2A Domains of Synaptotagmins
2000 StandoutNobel
α-Latrotoxin and Its Receptors: Neurexins and CIRL/Latrophilins
2001 StandoutNobel
Identification of a Minimal Core of the Synaptic SNARE Complex Sufficient for Reversible Assembly and Disassembly
1998
Sr2+ Binding to the Ca2+ Binding Site of the Synaptotagmin 1 C2B Domain Triggers Fast Exocytosis without Stimulating SNARE Interactions
2003 StandoutNobel
Structural basis for the Golgi membrane recruitment of Sly1p by Sed5p
2002
NSF Function in Neurotransmitter Release Involves Rearrangement of the SNARE Complex Downstream of Synaptic Vesicle Docking
1998
Purification of the N-type calcium channel associated with syntaxin and synaptotagmin. A complex implicated in synaptic vesicle exocytosis.
1994
Membrane Fusion and Exocytosis
1999 StandoutNobel
α-Latrocrustatoxin Increases Neurotransmitter Release by Activating a Calcium Influx Pathway at Crayfish Neuromuscular Junction
1999
Bruchpilot Promotes Active Zone Assembly, Ca 2+ Channel Clustering, and Vesicle Release
2006 StandoutScienceNobel
Protein Sorting by Transport Vesicles
1996 StandoutScienceNobel
Syntaxin Modulation of Calcium Channels in Cortical Synaptosomes As Revealed by Botulinum Toxin C1
2000
PRESYNAPTIC RECEPTORS
1998
Neurexin Is Expressed on Nerves, But Not at Nerve Terminals, in the Electric Organ
1997
Identification of a syntaxin-binding site on N-Type calcium channels
1994
Two previously undescribed members of the mouse CPEB family of genes and their inducible expression in the principal cell layers of the hippocampus
2003 Nobel
Membrane Fusion: Grappling with SNARE and SM Proteins
2009 StandoutScienceNobel
Membrane fusion protein synexin (annexin VII) as a Ca2+/GTP sensor in exocytotic secretion.
1996
Nucleation of COPII Vesicular Coat Complex by Endoplasmic Reticulum to Golgi Vesicle SNAREs
1998 StandoutScienceNobel
The Mating of a Fly
1994 StandoutScienceNobel
Modulation of an early step in the secretory machinery in hippocampal nerve terminals
1998
Yeast Homotypic Vacuole Fusion: A Window on Organelle Trafficking Mechanisms
2000
Synaptic Assembly of the Brain in the Absence of Neurotransmitter Secretion
2000 StandoutScienceNobel
Conserved structural features of the synaptic fusion complex: SNARE proteins reclassified as Q- and R-SNAREs
1998
Neurotoxins Affecting Neuroexocytosis
2000 Standout
SynCAM, a Synaptic Adhesion Molecule That Drives Synapse Assembly
2002 StandoutScienceNobel
Works of Vincent O’Connor being referenced
Degenerating Synaptic Boutons in Prion Disease
2009
Subfield‐specific immediate early gene expression associated with hippocampal long‐term potentiation in vivo
2001
Fusion complex formation protects synaptobrevin against proteolysis by tetanus toxin light chain
1994
SNAP-mediated protein–protein interactions essential for neurotransmitter release
1995 StandoutNatureNobel
On the structure of the ‘synaptosecretosome’ Evidence for a neurexin/synaptotagmin/syntaxin/Ca2+channel complex
1993
C1q: the perfect complement for a synaptic feast?
2008
Synaptic vesicle exocytosis: Molecules and models
1994
The N‐ethylmaleimide‐sensitive fusion protein (NSF) is preferentially expressed in the nervous system
1994
Selective presynaptic degeneration in the synaptopathy associated with ME7-induced hippocampal pathology
2009
Latrotoxin Receptor Signaling Engages the UNC-13-Dependent Vesicle-Priming Pathway in C. elegans
2004
The Role of Microglia in Synaptic Stripping and Synaptic Degeneration: A Revised Perspective
2010
A Neuronal Sec1 Homolog Regulates Neurotransmitter Release at the Squid Giant Synapse
1998
Disruption of syntaxin-mediated protein interactions blocks neurotransmitter secretion
1997
Clostridial neurotoxins compromise the stability of a low energy SNARE complex mediating NSF activation of synaptic vesicle fusion.
1995
Regulation of Neurotransmitter Release Kinetics by NSF
1998 Science
Ca2+or Sr2+Partially Rescues Synaptic Transmission in Hippocampal Cultures Treated with Botulinum Toxin A and C, But Not Tetanus Toxin
1997