Citation Impact
Citing Papers
Preferential Generation of Follicular B Helper T Cells from Foxp3 + T Cells in Gut Peyer's Patches
2009 StandoutScienceNobel
Protein characterization of Saccharomyces cerevisiae RNA polymerase II after in vivo cross-linking
2007 StandoutNobel
Generation of ordered protein assemblies using rigid three-body fusion
2021 StandoutNobel
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
Transferrin receptor targeting by de novo sheet extension
2021 StandoutNobel
Mutations in NALP12 cause hereditary periodic fever syndromes
2008
Induction of interferon-stimulated gene expression and antiviral responses require protein deacetylase activity
2004 StandoutNobel
Hierarchical design of pseudosymmetric protein nanocages
2024 StandoutNatureNobel
Simple repeat sequences on the human Y chromosome are equally polymorphic as their autosomal counterparts
1992
Targeted Disruption of the Stat1 Gene in Mice Reveals Unexpected Physiologic Specificity in the JAK–STAT Signaling Pathway
1996 Standout
Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
2001 StandoutNature
β-Catenin regulates expression of cyclin D1 in colon carcinoma cells
1999 StandoutNature
Dendritic Cell-specific MHC Class II Transactivator Contains a Caspase Recruitment Domain That Confers Potent Transactivation Activity
2001
Sequential Waves of Functionally Related Proteins Are Expressed When B Cells Prepare for Antibody Secretion
2003
NODs: intracellular proteins involved in inflammation and apoptosis
2003
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Unravelling the pathogenesis of inflammatory bowel disease
2007 StandoutNature
Environment Drives Selection and Function of Enhancers Controlling Tissue-Specific Macrophage Identities
2014
Indispensable Role of the Runx1-Cbfβ Transcription Complex for In Vivo-Suppressive Function of FoxP3+ Regulatory T Cells
2009 StandoutNobel
A role for mitochondria in NLRP3 inflammasome activation
2010 StandoutNature
Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1
2007 StandoutNatureNobel
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
2001 StandoutNature
Effector functions of NLRs in the intestine: innate sensing, cell death, and disease
2012
A novel IL-4 responsive element of the Eα MHC class II promoter that binds to an inducible factor
1995
Analysis of protein complexes using mass spectrometry
2007
Rapid online buffer exchange for screening of proteins, protein complexes and cell lysates by native mass spectrometry
2020 StandoutNobel
The NOD: a signaling module that regulates apoptosis and host defense against pathogens
2001
Caspase Functions in Cell Death and Disease
2013 Standout
A Novel Role for the Major Histocompatibility Complex Class II Transactivator CIITA in the Repression of IL-4 Production
1999
Structure of the winged-helix protein hRFX1 reveals a new mode of DNA binding
2000 Nature
Structural and functional diversity in the leucine-rich repeat family of proteins
1996
DNA methylation controls Foxp3 gene expression
2008
Expression of MHC class II molecules in different cellular and functional compartments is controlled by differential usage of multiple promoters of the transactivator CIITA
1997
The Inflammasomes
2010 Standout
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene
1996 StandoutNatureNobel
Transcriptional control of lymphoid development: lessons from gene targeting
1996
The Primary Immunodeficiencies
1995
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
2016 StandoutNatureNobel
Epigenetic Control of the foxp3 Locus in Regulatory T Cells
2007
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Innate Immune Receptors
2016
Pathogen Recognition and Innate Immunity
2006 Standout
The plant immune system
2006 StandoutNature
Identification of Distinct Regions of 5′ Flanking DNA That Mediate Constitutive, IFN-γ, STAT1, and TGF-β-Regulated Expression of the Class II Transactivator Gene
1998
HOW CELLS RESPOND TO INTERFERONS
1998 Standout
Nods, Nalps and Naip: intracellular regulators of bacterial-induced inflammation
2003
PLANT DISEASE RESISTANCE GENES
1997 Standout
Paternal and maternal DNA lineages reveal a bottleneck in the founding of the Finnish population.
1996 StandoutNobel
The Dendritic Cell Populations of Mouse Lymph Nodes
2001
STATs and Gene Regulation
1997 StandoutScience
Interactions Between the Microbiota and the Immune System
2012 StandoutScience
Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte Activation
2000 StandoutNobel
Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A
2011 StandoutNobel
Antiviral Actions of Interferons
2001 Standout
Network of dendritic cells within the muscular layer of the mouse intestine
2005 StandoutNobel
The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation
2011 StandoutScience
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Class II transactivator (CIITA) is sufficient for the inducible expression of major histocompatibility complex class II genes.
1994
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
Emerging Challenges in Regulatory T Cell Function and Biology
2007 StandoutScienceNobel
Msx2-interacting nuclear target protein (Mint) deficiency reveals negative regulation of early thymocyte differentiation by Notch/RBP-J signaling
2007 StandoutNobel
CELLULAR RESPONSES TO INTERFERON-γ
1997 Standout
Toll-related receptors and the control of antimicrobial peptide expression inDrosophila
2000 StandoutNobel
Computational design of mechanically coupled axle-rotor protein assemblies
2022 StandoutScienceNobel
The Danger Model: A Renewed Sense of Self
2002 StandoutScience
Identification of distinct regions of 5' flanking DNA that mediate constitutive, IFN-gamma, STAT1, and TGF-beta-regulated expression of the class II transactivator gene.
1998
RNA Scanning of a Molecular Machine with a Built-in Ruler
2016 StandoutNobel
Modulation of Major Histocompatibility Class II Protein Expression by Varicella-Zoster Virus
2000
Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation
2020 StandoutNobel
Loss of Runx3 function in leukocytes is associated with spontaneously developed colitis and gastric mucosal hyperplasia
2004
Human Cytomegalovirus Inhibits Major Histocompatibility Complex Class II Expression By Disruption of the Jak/Stat Pathway
1998
Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection
2004 StandoutNobel
Host-Gut Microbiota Metabolic Interactions
2012 StandoutScience
NOD-LRR PROTEINS: Role in Host-Microbial Interactions and Inflammatory Disease
2005
Phylogenetic Perspectives in Innate Immunity
1999 StandoutScienceNobel
MOLECULAR GENETICS OF T CELL DEVELOPMENT
2004
Cloning and functional characterization of mammalian homologues of the COPII component Sec23.
1996 StandoutNobel
Mycobacterium tuberculosisInhibits Macrophage Responses to IFN-γ through Myeloid Differentiation Factor 88-Dependent and -Independent Mechanisms
2004
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
De novo design of protein logic gates
2020 StandoutScienceNobel
Inhibition of IFN-γ-Induced Class II Transactivator Expression by a 19-kDa Lipoprotein fromMycobacterium tuberculosis: A Potential Mechanism for Immune Evasion
2003
Histone Deacetylase 1/mSin3A Disrupts Gamma Interferon-Induced CIITA Function and Major Histocompatibility Complex Class II Enhanceosome Formation
2003
Defective Lymphoid Development in Mice Lacking Jak3
1995 StandoutScienceNobel
The BB1 Monoclonal Antibody Recognizes Both Cell Surface CD74 (MHC Class II-Associated Invariant Chain) as Well as B7-1 (CD80), Resolving the Question Regarding a Third CD28/CTLA-4 Counterreceptor
1998
Proteins with leucine-rich repeats
1995 Nobel
CATERPILLER: A Novel Gene Family Important in Immunity, Cell Death, and Diseases
2004
Works of Viktor Steimle being referenced
The two novel MHC class II transactivators RFX5 and CIITA both control expression of HLA-DM genes
1995
MHC Class II‐Deficient Combined Immunodeficiency: A Disease of Gene Regulation
1994
Two novel mutations in the MHC class II transactivator CIITA in a second patient from MHC class II deficiency complementation group A
1997
Molecular defects in the bare lymphocyte syndrome and regulation of MHC class II genes
1995
Developmental extinction of major histocompatibility complex class II gene expression in plasmocytes is mediated by silencing of the transactivator gene CIITA.
1994
CIITA Leucine-Rich Repeats Control Nuclear Localization, In Vivo Recruitment to the Major Histocompatibility Complex (MHC) Class II Enhanceosome, and MHC Class II Gene Transactivation
2000
REGULATION OF MHC CLASS II GENES: Lessons from a Disease
1996
Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)
1993
Mutation in the Class II trans-Activator Leading to a Mild Immunodeficiency
2001
Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)
1993
CIITA is a transcriptional coactivator that is recruited to MHC class II promoters by multiple synergistic interactions with an enhanceosome complex
2000
Hypervariability of intronic simple (gt)n(ga)m repeats in HLA-DRB genes
1990
Runx3 Regulates Integrin αE/CD103 and CD4 Expression during Development of CD4−/CD8+ T Cells
2005
A novel DNA-binding regulatory factor is mutated in primary MHC class II deficiency (bare lymphocyte syndrome).
1995
Two-dimensional Blue Native/SDS Gel Electrophoresis of Multi-Protein Complexes from Whole Cellular Lysates
2003
Morpholino Antisense Oligonucleotide-Mediated Gene Knockdown During Thymocyte Development Reveals Role for Runx3 Transcription Factor in CD4 Silencing During Development of CD4−/CD8+ Thymocytes
2003
Regulation of MHC Class II Expression by Interferon-γ Mediated by the Transactivator Gene CIITA
1994 Science