Citation Impact
Citing Papers
Molecular Dissection of Formation of Senescence-Associated Heterochromatin Foci
2007
Wnt-inhibitory factor 1 dysregulation of the bone marrow niche exhausts hematopoietic stem cells
2011
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter
2010 StandoutNobel
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
Frequent Mutations of Chromatin Remodeling Gene ARID1A in Ovarian Clear Cell Carcinoma
2010 StandoutScience
Distinct fibroblast lineages determine dermal architecture in skin development and repair
2013 StandoutNature
Comprehensive molecular portraits of human breast tumours
2012 StandoutNature
mTOR Regulation and Therapeutic Rejuvenation of Aging Hematopoietic Stem Cells
2009
SIRT3 Reverses Aging-Associated Degeneration
2013
Hallmarks of Cancer: The Next Generation
2011 Standout
Secreted Frizzled-Related Protein 1 Extrinsically Regulates Cycling Activity and Maintenance of Hematopoietic Stem Cells
2009
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
An integrated encyclopedia of DNA elements in the human genome
2012 StandoutNature
The DNA-damage response in human biology and disease
2009 StandoutNature
Genome-scale DNA methylation maps of pluripotent and differentiated cells
2008 StandoutNature
Noncanonical Wnt Signaling Maintains Hematopoietic Stem Cells in the Niche
2012
The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells
2007
Long-term haematopoietic reconstitution by Trp53-/-p16Ink4a-/-p19Arf-/- multipotent progenitors
2008 Nature
Telomerase Reverse Transcriptase Delays Aging in Cancer-Resistant Mice
2008
mTOR Signaling in Growth Control and Disease
2012 Standout
Circular RNAs are a large class of animal RNAs with regulatory potency
2013 StandoutNature
Rb Regulates Interactions between Hematopoietic Stem Cells and Their Bone Marrow Microenvironment
2007
Regulatory Mechanisms of Tumor Suppressor P16INK4Aand Their Relevance to Cancer
2011
ChIP–seq: advantages and challenges of a maturing technology
2009
Gi-Coupled GPCR Signaling Controls the Formation and Organization of Human Pluripotent Colonies
2009 StandoutNobel
Epigenetic regulation of aging stem cells
2011
Cellular senescence: when bad things happen to good cells
2007 Standout
The genetics of ageing
2010 StandoutNature
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
2013 StandoutNature
Ionizing radiation‐induced long‐term expression of senescence markers in mice is independent of p53 and immune status
2010
Increased skeletal VEGF enhances β‐catenin activity and results in excessively ossified bones
2009
Cellular Senescence in Cancer and Aging
2007 Standout
Cellular senescence and organismal aging
2008
The bone marrow at the crossroads of blood and immunity
2011
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
2011 StandoutNature
Expression of p16INK4a in peripheral blood T‐cells is a biomarker of human aging
2009
The Epigenomics of Cancer
2007 Standout
The bone marrow niche for haematopoietic stem cells
2014 StandoutNature
Rescue of key features of the p63‐null epithelial phenotype by inactivation of Ink4a and Arf
2009
Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells
2008 Nature
ROS Function in Redox Signaling and Oxidative Stress
2014 Standout
Targeting HIF1α Eliminates Cancer Stem Cells in Hematological Malignancies
2011
p16INK4a induces an age-dependent decline in islet regenerative potential
2006 Nature
Expression of Linear and Novel Circular Forms of an INK4/ARF-Associated Non-Coding RNA Correlates with Atherosclerosis Risk
2010
WNT signalling in the immune system: WNT is spreading its wings
2008
WNT signaling in bone homeostasis and disease: from human mutations to treatments
2013 Standout
Cadherin-Based Adhesion Is a Potential Target for Niche Manipulation to Protect Hematopoietic Stem Cells in Adult Bone Marrow
2010
How stem cells age and why this makes us grow old
2007
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Forging a signature of in vivo senescence
2015
Bmi1 regulates mitochondrial function and the DNA damage response pathway
2009 Nature
mTOR: from growth signal integration to cancer, diabetes and ageing
2010 Standout
Principles of adoptive T cell cancer therapy
2007
Altered senescence, apoptosis, and DNA damage response in a mutant p53 model of accelerated aging
2009
Anti‐aging activity of the Ink4/Arf locus
2009
Epigenetics and aging: the targets and the marks
2007
Tumor Suppressor and Aging Biomarker p16INK4a Induces Cellular Senescence without the Associated Inflammatory Secretory Phenotype
2011
A common variant of the p16INK4a genetic region is associated with physical function in older people
2007
Integrating Physiological Regulation with Stem Cell and Tissue Homeostasis
2011
Cellular senescence: putting the paradoxes in perspective
2010
Stems Cells and the Pathways to Aging and Cancer
2008
Senescent Cells: A Novel Therapeutic Target for Aging and Age-Related Diseases
2012
Suppression of Wnt Signaling by Dkk1 Attenuates PTH-Mediated Stromal Cell Response and New Bone Formation
2010
The common biology of cancer and ageing
2007 Nature
Healing and Hurting: Molecular Mechanisms, Functions, and Pathologies of Cellular Senescence
2009
Two faces of p53: aging and tumor suppression
2007
Emerging models and paradigms for stem cell ageing
2011
Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone
2014 StandoutNature
Cancer immunotherapy comes of age
2011 StandoutNature
Evidence that senescent human prostate epithelial cells enhance tumorigenicity: Cell fusion as a potential mechanism and inhibition by p16INK4a and hTERT
2007
Charting histone modifications and the functional organization of mammalian genomes
2010
Immortalization eliminates a roadblock during cellular reprogramming into iPS cells
2009 Nature
Muscle-derived stem/progenitor cell dysfunction limits healthspan and lifespan in a murine progeria model
2012
Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia
2010 Nature
Cell cycle, CDKs and cancer: a changing paradigm
2009 Standout
Delayed ageing through damage protection by the Arf/p53 pathway
2007 Nature
The role of senescent cells in ageing
2014 StandoutNature
Clonal evolution in cancer
2012 StandoutNature
Aberrant Epigenetic Landscape in Cancer: How Cellular Identity Goes Awry
2010
Widespread transcription at neuronal activity-regulated enhancers
2010 StandoutNature
The Hallmarks of Aging
2013 Standout
CDK Inhibitor p18INK4c Is a Downstream Target of GATA3 and Restrains Mammary Luminal Progenitor Cell Proliferation and Tumorigenesis
2009
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
Angiocrine factors from Akt-activated endothelial cells balance self-renewal and differentiation of haematopoietic stem cells
2010
DNA damage response and cellular senescence in tissues of aging mice
2009
Human DNA methylomes at base resolution show widespread epigenomic differences
2009 StandoutNature
The Regulation of INK4/ARF in Cancer and Aging
2006
Cdc42 Activity Regulates Hematopoietic Stem Cell Aging and Rejuvenation
2012
Enhancer function: new insights into the regulation of tissue-specific gene expression
2011
Regulatory networks defining EMT during cancer initiation and progression
2013 Standout
The Polycomb complex PRC2 and its mark in life
2011 StandoutNature
Opposing roles for p16Ink4a and p19Arf in senescence and ageing caused by BubR1 insufficiency
2008
Chromatin Signatures in Multipotent Human Hematopoietic Stem Cells Indicate the Fate of Bivalent Genes during Differentiation
2009
Mechanisms that Regulate Stem Cell Aging and Life Span
2013
Nuclear reprogramming to a pluripotent state by three approaches
2010 StandoutNatureNobel
Monitoring Tumorigenesis and Senescence In Vivo with a p16INK4a-Luciferase Model
2013
The role of Dickkopf-1 in bone development, homeostasis, and disease
2008
The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression
2010 Standout
Regulation of Hematopoietic Stem Cells by the Steel Factor/KIT Signaling Pathway
2008
Reconstructing the DNA Methylation Maps of the Neandertal and the Denisovan
2014 StandoutScienceNobel
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
Four faces of cellular senescence
2011 Standout
TSC–mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species
2008
Cancer Genome Landscapes
2013 StandoutScience
AKT1 and AKT2 maintain hematopoietic stem cell function by regulating reactive oxygen species
2010
In vivo hematopoietic stem cell modification by mRNA delivery
2023 StandoutScienceNobel
Regulation of Bone Marrow-Derived Vascular Progenitor Cell Mobilization and Maintenance
2010
Epithelial Plasticity: A Common Theme in Embryonic and Cancer Cells
2013 StandoutScience
Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment
2022 StandoutNobel
Ankyrin Repeat: A Unique Motif Mediating Protein−Protein Interactions
2006
Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
2008 StandoutNobel
The Essential Functions of Adipo-osteogenic Progenitors as the Hematopoietic Stem and Progenitor Cell Niche
2010
featureCounts: an efficient general purpose program for assigning sequence reads to genomic features
2013 Standout
The Biology of Cancer Stem Cells
2007
Knockdown of N-cadherin suppresses the long-term engraftment of hematopoietic stem cells
2010
The Molecular Balancing Act of p16INK4a in Cancer and Aging
2013
Works of Viktor Janzen being referenced
Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a
2006 Nature
Wnt Signaling in the Niche Enforces Hematopoietic Stem Cell Quiescence and Is Necessary to Preserve Self-Renewal In Vivo
2008
Hematopoietic Stem Cell Responsiveness to Exogenous Signals Is Limited by Caspase-3
2008
Nf2/Merlin Regulates Hematopoietic Stem Cell Behavior by Altering Microenvironmental Architecture
2008
Differential H3K4 Methylation Identifies Developmentally Poised Hematopoietic Genes
2008
The EMT regulator Zeb2/Sip1 is essential for murine embryonic hematopoietic stem/progenitor cell differentiation and mobilization
2011
Stromal Cell-Derived Factor-1/CXCR4 Signaling Modifies the Capillary-Like Organization of Human Embryonic Stem Cell-Derived Endothelium In Vitro
2006