Citation Impact
Citing Papers
The metalloproteinase MT1-MMP is required for normal development and maintenance of osteocyte processes in bone
2004
β-Arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2
2009 StandoutNobel
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
Shear-induced unfolding triggers adhesion of von Willebrand factor fibers
2007 Standout
Alpelisib for PIK3CA -Mutated, Hormone Receptor–Positive Advanced Breast Cancer
2019 Standout
A single ubiquitin is sufficient for cargo protein entry into MVBs in the absence of ESCRT ubiquitination
2011
Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality
2020 StandoutNobel
A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication
2008
Matrix Metalloproteinase-Induced Epithelial-Mesenchymal Transition in Breast Cancer
2010
Substrate Filtering by the Active Site Crossover Loop in UCHL3 Revealed by Sortagging and Gain-of-function Mutations
2008
Mice with hyper-long telomeres show less metabolic aging and longer lifespans
2019
MMP-13 Plays a Role in Keratinocyte Migration, Angiogenesis, and Contraction in Mouse Skin Wound Healing
2009
Regulation of Type II Transmembrane Serine Proteinase TMPRSS6 by Hypoxia-inducible Factors
2010 StandoutNobel
Re-epithelialization and immune cell behaviour in an ex vivo human skin model
2020 Standout
Matrix metalloproteinases: a tail of a frog that became a prince
2002
In vivo cyclic induction of the FOXM1 transcription factor delays natural and progeroid aging phenotypes and extends healthspan
2022
Chromatin Reader Brd4 Functions in Ig Class Switching as a Repair Complex Adaptor of Nonhomologous End-Joining
2014 StandoutNobel
Cancer Invasion and the Microenvironment: Plasticity and Reciprocity
2011 Standout
Matrix metalloproteinases and the regulation of tissue remodelling
2007 Standout
Inflammation and cancer
2002 StandoutNature
A view on drug resistance in cancer
2019 StandoutNature
Liver fibrosis
2005 Standout
Regulation of DNA Damage Responses by Ubiquitin and SUMO
2013
Cellular senescence: when bad things happen to good cells
2007 Standout
Drosophila Matrix Metalloproteinases Are Required for Tissue Remodeling, but Not Embryonic Development
2003
Cellular senescence in aging and age-related disease: from mechanisms to therapy
2015 Standout
JNK‐ and Fos‐regulated Mmp1 expression cooperates with Ras to induce invasive tumors in Drosophila
2006
Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future
2017 Standout
Hallmarks of aging: An expanding universe
2023 Standout
Strategies for MMP inhibition in cancer: innovations for the post-trial era
2002
A Genomic and Functional Inventory of Deubiquitinating Enzymes
2005 Standout
Reprogramming aging and progeria
2012
The role of chondrocyte senescence in osteoarthritis
2002
Structure-guided mutagenesis of a mucin-selective metalloprotease from Akkermansia muciniphila alters substrate preferences
2022 StandoutNobel
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Micromanaging aging with miRNAs
2011
Primary open-angle glaucoma
2004 Standout
Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory response
2012
Novel highly selective inhibitors of ubiquitin specific protease 30 (USP30) accelerate mitophagy
2018
Dissecting muscle and neuronal disorders in a Drosophila model of muscular dystrophy
2007 StandoutNobel
Ubiquitin and ubiquitin-like specific proteases targeted by infectious pathogens: Emerging patterns and molecular principles
2008
High incidence of ubiquitin‐like domains in human ubiquitin‐specific proteases
2007
Human and mouse proteases: a comparative genomic approach
2003
DDR2 receptor promotes MMP-2–mediated proliferation and invasion by hepatic stellate cells
2001
Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites
2021 StandoutNobel
Breaking the chains: structure and function of the deubiquitinases
2009 Standout
Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
2010 Standout
Iron refractory iron deficiency anemia
2013
Initial sequence of the chimpanzee genome and comparison with the human genome
2005 StandoutNature
Remodelling the extracellular matrix in development and disease
2014 Standout
Matrix metalloproteinases as modulators of inflammation and innate immunity
2004 Standout
Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering
2005 Standout
The Ubiquitin Binding Domain ZnF UBP Recognizes the C-Terminal Diglycine Motif of Unanchored Ubiquitin
2006
Role of matrix metalloproteinases in epithelial migration
2009
Ab initio protein modelling reveals novel human MIT domains
2009
A Genomic Analysis of Rat Proteases and Protease Inhibitors
2004
Néstor–Guillermo progeria syndrome: A novel premature aging condition with early onset and chronic development caused by BANF1 mutations
2011
Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice
2019
Tumor metastasis: mechanistic insights and clinical challenges
2006 Standout
Proteolytic networks in cancer
2011
The Hallmarks of Aging
2013 Standout
Idiopathic pulmonary fibrosis
2011 Standout
Iron-Refractory Iron Deficiency Anemia (IRIDA)
2014
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
The PI3K Pathway in Human Disease
2017 Standout
Ocular Hypertension in Mice with a Targeted Type I Collagen Mutation
2003
TMPRSS6, but not TF, TFR2 or BMP2 variants are associated with increased risk of iron-deficiency anemia
2012
Metastatic ability of Drosophila tumors depends on MMP activity
2006
The Ubiquitin-Specific Protease Usp4 Regulates the Cell Surface Level of the A2a Receptor
2005
The Transcription Factor Mef2 Links the Drosophila Core Clock to Fas2, Neuronal Morphology, and Circadian Behavior
2013 StandoutNobel
Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
2009 Standout
Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver
2008 Standout
New functions for the matrix metalloproteinases in cancer progression
2002 Standout
Matrix metalloproteinases in cancer: from new functions to improved inhibition strategies
2004
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
2017 Standout
Cleavage of ultra‐large von Willebrand factor by ADAMTS‐13 under flow conditions
2005
Mechanisms, biology and inhibitors of deubiquitinating enzymes
2007
Secreted Versus Membrane-anchored Collagenases
2009
An MMP liberates the Ninjurin A ectodomain to signal a lossof cell adhesion
2006
Clonal status of actionable driver events and the timing of mutational processes in cancer evolution
2015
Crystal Structures of Protein-Bound Cyclic Peptides
2019
The Phanerozoic Record of Global Sea-Level Change
2005 StandoutScience
ADAMTS-1 Metalloproteinase Promotes Tumor Development through the Induction of a Stromal Reaction In vivo
2008
Molecular Pathology of Laminopathies
2021
Drosophila TIMP Is a Potent Inhibitor of MMPs and TACE: Similarities in Structure and Function to TIMP-3
2003
Nucleolar structure and function are regulated by the deubiquitylating enzyme USP36
2009
The extracellular matrix: A dynamic niche in cancer progression
2012 Standout
Postglacial variations in the level of the sea: Implications for climate dynamics and solid‐Earth geophysics
1998
Distinct functions for the catalytic and hemopexin domains of a Drosophila matrix metalloproteinase
2009
Sea Level Change Through the Last Glacial Cycle
2001 StandoutScience
Progress and trends in the development of therapies for Hutchinson–Gilford progeria syndrome
2020
Regulation of Mitochondrial Morphology by USP30, a Deubiquitinating Enzyme Present in the Mitochondrial Outer Membrane
2008
Architecture and function of metallopeptidase catalytic domains
2013
Splicing-Directed Therapy in a New Mouse Model of Human Accelerated Aging
2011
Metabolic reprogramming and cancer progression
2020 StandoutScience
Fibrosis — A Common Pathway to Organ Injury and Failure
2015 Standout
Disruption of Wnt/β-Catenin Signaling and Telomeric Shortening Are Inextricable Consequences of Tankyrase Inhibition in Human Cells
2015
Membrane-bound serine protease matriptase-2 (Tmprss6) is an essential regulator of iron homeostasis
2008
Basigin (EMMPRIN/CD147) interacts with integrin to affect cellular architecture
2005
Iron-Deficiency Anemia
2015 Standout
Protease degradomics: A new challenge for proteomics
2002
Diverse functions of matrix metalloproteinases during fibrosis
2014
LINE-1 RNA causes heterochromatin erosion and is a target for amelioration of senescent phenotypes in progeroid syndromes
2022
Mouse Models to Disentangle the Hallmarks of Human Aging
2018
Tumor cell traffic through the extracellular matrix is controlled by the membrane-anchored collagenase MT1-MMP
2004
Matrix metalloproteinases promote motor axon fasciculation in theDrosophilaembryo
2007
How Matrix Metalloproteinases Regulate Cell Behavior
2001 Standout
The Ubiquitin Code
2012 Standout
Critical roles for collagenase-3 (Mmp13) in development of growth plate cartilage and in endochondral ossification
2004
How I manage patients with atypical microcytic anaemia
2012
Scar-Associated Macrophages Are a Major Source of Hepatic Matrix Metalloproteinase-13 and Facilitate the Resolution of Murine Hepatic Fibrosis
2007
Trafficking of G Protein–Coupled Receptors
2006 StandoutNobel
Histone Deacetylases in Herpesvirus Replication and Virus-Stimulated Host Defense
2013
Increased inflammation delays wound healing in mice deficient in collagenase‐2 (MMP‐8)
2007
Phosphatidylinositol 3-Kinase, Growth Disorders, and Cancer
2018
Role of Extracellular Matrix in Adaptation of Tendon and Skeletal Muscle to Mechanical Loading
2004 Standout
Works of Vı́ctor Quesada being referenced
Progerin accelerates atherosclerosis by inducing endoplasmic reticulum stress in vascular smooth muscle cells
2019
Development of a CRISPR/Cas9-based therapy for Hutchinson–Gilford progeria syndrome
2019
Cell–cell adhesion genes CTNNA2 and CTNNA3 are tumour suppressors frequently mutated in laryngeal carcinomas
2013
Deubiquitinases in cancer: new functions and therapeutic options
2011
POT1 mutations cause telomere dysfunction in chronic lymphocytic leukemia
2013
Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases
2003
Structural and Enzymatic Characterization of Drosophila Dm2-MMP, a Membrane-bound Matrix Metalloproteinase with Tissue-specific Expression
2002
Matriptase-2 mutations in iron-refractory iron deficiency anemia patients provide new insights into protease activation mechanisms
2009
Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains
2002
Exome sequencing identifies a novel mutation in PIK3R1 as the cause of SHORT syndrome
2014
The Degradome database: mammalian proteases and diseases of proteolysis
2008
Exome Sequencing and Functional Analysis Identifies BANF1 Mutation as the Cause of a Hereditary Progeroid Syndrome
2011
The Degradome database: expanding roles of mammalian proteases in life and disease
2015
Identification and Characterization of ADAMTS-20 Defines a Novel Subfamily of Metalloproteinases-Disintegrins with Multiple Thrombospondin-1 Repeats and a Unique GON Domain
2003
Secular variations in latitudes and longitudes and continental drift
1974
Apicomplexan UCHL3 retains dual specificity for ubiquitin and Nedd8 throughout evolution
2007
Identification and Enzymatic Characterization of Two Diverging Murine Counterparts of Human Interstitial Collagenase (MMP-1) Expressed at Sites of Embryo Implantation
2001
A Functional Ubiquitin-Specific Protease Embedded in the Large Tegument Protein (ORF64) of Murine Gammaherpesvirus 68 Is Active during the Course of Infection
2007
Polyserase-I, a human polyprotease with the ability to generate independent serine protease domains from a single translation product
2003
Novel LMNA mutations cause an aggressive atypical neonatal progeria without progerin accumulation
2016