Citation Impact
Citing Papers
An X Chromosome Gene, WTX , Is Commonly Inactivated in Wilms Tumor
2007 Science
Zinc Finger-DNA Recognition: Crystal Structure of a Zif268-DNA Complex at 2.1 Å
1991 StandoutScience
Concordant Regulation of Gene Expression by Hypoxia and 2-Oxoglutarate-dependent Dioxygenase Inhibition
2006 StandoutNobel
Discovery of archaeal fusexins homologous to eukaryotic HAP2/GCS1 gamete fusion proteins
2022 StandoutNobel
Effects of an Rb mutation in the mouse
1992 StandoutNature
On the allelic spectrum of human disease
2001
Caught up in a Wnt storm: Wnt signaling in cancer
2003
Disruption of insulin–like growth factor 2 imprinting in Beckwith–Wiedemann syndrome
1993
WAF1, a potential mediator of p53 tumor suppression
1993 Standout
WT-1 is required for early kidney development
1993 Standout
Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene
1994 StandoutNature
Therapeutic Strategies for Targeting Ras Proteins
2011
The changing of the guard: Molecular diversity and rapid evolution of β-defensins
2006
Defensins: antimicrobial peptides of innate immunity
2003 Standout
A genetic model for colorectal tumorigenesis
1990 Standout
An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor
1990
Understanding the recent evolution of the human genome: insights from human-chimpanzee genome comparisons
2006
APC mutations occur early during colorectal tumorigenesis
1992 StandoutNature
Tumor suppressor genes
1991 Standout
Genetic Patterns in Head and Neck Cancers That Contain or Lack Transcriptionally Active Human Papillomavirus
2004
Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping
1990 StandoutNature
PLINK: A Tool Set for Whole-Genome Association and Population-Based Linkage Analyses
2007 Standout
Dehydrated hereditary stomatocytosis linked to gain-of-function mutations in mechanically activated PIEZO1 ion channels
2013 StandoutNobel
Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li–Fraumeni syndrome
1990 StandoutNature
Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets
2017 StandoutNobel
Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene
2000 StandoutNature
The candidate Wilms' tumour gene is involved in genitourinary development
1990 Nature
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
Molecular cloning oflin-29, a heterochronic gene required for the differentiation of hypodermal cells and the cessation of molting inC.elegans
1991 StandoutNobel
Wnt/β-Catenin Signaling and Disease
2012 Standout
Familial bone marrow monosomy 7. Evidence that the predisposing locus is not on the long arm of chromosome 7.
1989
Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules
1991 StandoutNature
Genetic and Epigenetic Losses of Heterozygosity in Cancer Predisposition and Progression
1990
Microdeletions and microinsertions causing human genetic disease: common mechanisms of mutagenesis and the role of local DNA sequence complexity
2005
Human Papillomavirus and Survival of Patients with Oropharyngeal Cancer
2010 Standout
Patterning of the Caenorhabditis elegans head region by the Pax-6 family member vab-3
1995 StandoutNatureNobel
Oncogenes and signal transduction
1991 Standout
Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret
1994 StandoutNature
Loss of heterozygosity at chromosome regions 22q11–12 and 11p15.5 in renal rhabdoid tumors
1996
SOX9 Regulates Prostaglandin D Synthase Gene Transcription in Vivo to Ensure Testis Development
2007
Analysis and Separation of Residues Important for the Chemoattractant and Antimicrobial Activities of β-Defensin 3
2008 StandoutNobel
Molecular themes in oncogenesis
1991 StandoutNobel
Fusion activity of lipid-anchored envelope glycoproteins of herpes simplex virus type 1
2004
Evidence implicating heterozygous deletion of chromosome 7 in the pathogenesis of familial leukemia associated with monosomy 7
1992
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
2018 StandoutNobel
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
1992 StandoutNature
Microsatellite Instability in Human Cancer: A Prognostic Marker for Chemotherapy?
1999
Sox18 induces development of the lymphatic vasculature in mice
2008 StandoutNature
Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
2017 StandoutNature
Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer
1998 StandoutNature
Genomic structure, evolutionary conservation and aniridia mutations in the human PAX6 gene
1992
A 450-kb contig of defensin genes on human chromosome 8p23
1999
Primate defensins
2004
Wnt signalling in stem cells and cancer
2005 StandoutNature
Drugging the undruggable RAS: Mission Possible?
2014
Cyclin A and the retinoblastoma gene product complex with a common transcription factor
1991 StandoutNatureNobel
Renal agenesis and the absence of enteric neurons in mice lacking GDNF
1996 StandoutNature
Parental origin of mutations of the retinoblastoma gene
1989 Nature
Head and Neck Cancer
2001 Standout
A catalogue of imprinted genes and parent-of-origin effects in humans and animals
1998
WT1 mutations contribute to abnormal genital system development and hereditary Wilms' tumour
1991 Nature
Familial Wiedemann-Beckwith syndrome and a second Wilms tumor locus both map to 11p15.5.
1989
A gene for Wilms tumour?
1990 Nature
Use of allelic loss to predict malignant risk for low-grade oral epithelial dysplasia.
2000
Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus
1990 Standout
Tumor Suppressor Genes: The Puzzle and the Promise
1989 Science
Tumor Suppressor Genes
1991 Science
Role for the Wilms tumor gene in genital development?
1990
The rate of telomere sequence loss in human leukocytes varies with age
1998 StandoutNobel
The Galvanization of Biology: A Growing Appreciation for the Roles of Zinc
1996 StandoutScience
Reconstructing the DNA Methylation Maps of the Neandertal and the Denisovan
2014 StandoutScienceNobel
Tumor-specific loss of 11p15.5 alleles in del11p13 Wilms tumor and in familial adrenocortical carcinoma.
1989
Molecular mechanisms of oncogenesis.
1989
Essential role of β-adrenergic receptor kinase 1 in cardiac development and function
1996 StandoutNobel
Tumor Microsatellite-Instability Status as a Predictor of Benefit from Fluorouracil-Based Adjuvant Chemotherapy for Colon Cancer
2003 Standout
Epigenetic changes at the insulin-like growth factor II/ H19 locus in developing kidney is an early event in Wilms tumorigenesis
1997
Linkage of Early-Onset Familial Breast Cancer to Chromosome 17q21
1990 StandoutScience
Osteopontin Promotes Hepatic Progenitor Cell Expansion and Tumorigenicity via Activation of β-Catenin in Mice
2015
Type 1 Neurofibromatosis Gene: Identification of a Large Transcript Disrupted in Three NF1 Patients
1990 StandoutScience
A case-control study confirms that microsatellite assay can identify patients at risk of developing oral squamous cell carcinoma within a field of cancerization.
2000
G 1 Events and Regulation of Cell Proliferation
1989 StandoutScience
Chromosome Aberrations and Cancer
1991 Science
Low incidence of loss of chromosome 10 in sporadic and hereditary human medullary thyroid carcinoma.
1989
Distal deletion of chromosome Ip in ductal carcinoma of the breast.
1989
Exclusion of the retinoblastoma gene and chromosome 13q as the site of a primary lesion for human breast cancer.
1990
Human DNA Repair Genes
2001 StandoutScienceNobel
Mutations in SDHD , a Mitochondrial Complex II Gene, in Hereditary Paraganglioma
2000 StandoutScience
WISP genes are members of the connective tissue growth factor family that are up-regulated in Wnt-1-transformed cells and aberrantly expressed in human colon tumors
1998
DPC4 , A Candidate Tumor Suppressor Gene at Human Chromosome 18q21.1
1996 StandoutScience
Works of Vicki Huff being referenced
β-Catenin Activation in a Novel Liver Progenitor Cell Type Is Sufficient to Cause Hepatocellular Carcinoma and Hepatoblastoma
2014
The Wilms tumor gene, Wt1 , is required for Sox9 expression and maintenance of tubular architecture in the developing testis
2006
Lack of linkage of familial Wilms' tumour to chromosomal band 11 p13
1988 Nature
Mutation in thePAX6 gene in twenty patients with aniridia
2000
Wilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models
2010
Genetic mosaicism in normal tissues of Wilms' tumour patients
1993
Smallest region of overlap in Wilms tumor deletions uniquely implicates an 11p13 zinc finger gene as the disease locus
1991
Inheritance of Unequal Numbers of the Genes Encoding the Human Neutrophil Defensins HP-1 and HP-3
1995
Frequent association of beta-catenin and WT1 mutations in Wilms tumors.
2000
The carboxy-terminal 41 amino acids of herpes simplex virus type 1 glycoprotein B are not essential for production of infectious virus particles
1988
Sequential loss of heterozygosity at microsatellite motifs in preinvasive and invasive head and neck squamous carcinoma.
1995
Evidence for WT1 as a Wilms tumor (WT) gene: intragenic germinal deletion in bilateral WT.
1991
Structural analysis of the human nov proto-oncogene and expression in Wilms tumor.
1994
Parental origin of de novo constitutional deletions of chromosomal band 11p13.
1990
WT1 exon 1 deletion/insertion mutations in Wilms tumor patients, associated with di- and trinucleotide repeats and deletion hotspot consensus sequences.
1995
Microsatellite instability in preinvasive and invasive head and neck squamous carcinoma.
1996