Citation Impact
Citing Papers
Protein characterization of Saccharomyces cerevisiae RNA polymerase II after in vivo cross-linking
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Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O 2 -Regulated Prolyl Hydroxylation
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Controlling Macromolecular Topology with Genetically Encoded SpyTag–SpyCatcher Chemistry
2013 StandoutNobel
Multiubiquitin Chain Binding and Protein Degradation Are Mediated by Distinct Domains within the 26 S Proteasome Subunit Mcb1
1998
Mapping Subunit Contacts in the Regulatory Complex of the 26 S Proteasome
2000
Proteasome Involvement in Agonist-induced Down-regulation of μ and δ Opioid Receptors
2001
Valosin-containing protein is a multi-ubiquitin chain-targeting factor required in ubiquitin–proteasome degradation
2001
The 26S-proteasome: regulation and substrate recognition
1997
Proteolysis: The proteasome: a protein-degrading organelle?
1995
An Integrated Mass Spectrometry-based Proteomic Approach
2005
Quaternary Structure of the ATPase Complex of Human 26S Proteasomes Determined by Chemical Cross-Linking
2001
Cut and trim: generating MHC class I peptide ligands
2001
Structural basis for the recognition of hydroxyproline in HIF-1α by pVHL
2002 StandoutNatureNobel
Specific Interactions between ATPase Subunits of the 26 S Protease
1997
Deubiquitinating Enzymes: A New Class of Biological Regulators
1998
Localization of the 26S proteasome during mitosis and meiosis in fission yeast
1998
ATPase and ubiquitin-binding proteins of the yeast proteasome
1997
Intermediates in the formation of mouse 20S proteasomes: implications for the assembly of precursor beta subunits
1997
Amyloid β-Protein Inhibits Ubiquitin-dependent Protein Degradation in Vitro
1995
Ubiquitin in chains
2000
Ubiquitin, proteasomes, and the regulation of intracellular protein degradation
1995
Molecular properties of the proteasome activator PA28 family proteins and γ‐interferon regulation
1997
Structure of the proteasome activator REGα (PA28α)
1997 Nature
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
1998 StandoutNature
The Active Sites of the Eukaryotic 20 S Proteasome and Their Involvement in Subunit Precursor Processing
1997
Molecular cloning and expression of a multiubiquitin chain binding subunit of the human 26S protease
1996
Investigating the importance of proteasome-interaction for Rad23 function
2002
Proteasome Activation by REG Molecules Lacking Homolog-specific Inserts
1998
The 26S proteasome: assembly and function of a destructive machine
2010
Evidence for an Interaction between Ubiquitin-Conjugating Enzymes and the 26S Proteasome
2000
Origin and function of ubiquitin-like proteins
2009 Nature
The Ubiquitin-activating Enzyme E1 Is Phosphorylated and Localized to the Nucleus in a Cell Cycle-dependent Manner
1996 StandoutNobel
Characterization of Recombinant REGα, REGβ, and REGγ Proteasome Activators
1997
The ubiquitin-proteasome proteolytic pathway
1994 StandoutNobel
Evidence for the Existence of a Non-catalytic Modifier Site of Peptide Hydrolysis by the 20 S Proteasome
2000
Editing of ubiquitin conjugates by an isopeptidase in the 26S proteasome
1997 Nature
Nucleotidase Activities of the 26 S Proteasome and Its Regulatory Complex
1996
Lactacystin and clasto-Lactacystin β-Lactone Modify Multiple Proteasome β-Subunits and Inhibit Intracellular Protein Degradation and Major Histocompatibility Complex Class I Antigen Presentation
1997
Subunits of the regulatory complex of the 26S protease
1995
A protein conjugation system essential for autophagy
1998 StandoutNatureNobel
RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO
2002 StandoutNature
Homologues of 26S proteasome subunits are regulators of transcription and translation
1998
Primary structures of two homologous subunits of PA28, a γ‐interferon‐inducible protein activator of the 20S proteasome
1995
The Proteasome: Paradigm of a Self-Compartmentalizing Protease
1998
The Sizes of Peptides Generated from Protein by Mammalian 26 and 20 S Proteasomes
1999
Inhibition of Ubiquitin-mediated Proteolysis by the Arabidopsis 26 S Protease Subunit S5a
1995
cDNA Cloning, Expression, and Functional Characterization of PI31, a Proline-rich Inhibitor of the Proteasome
2000
Subcellular Localization, Stoichiometry, and Protein Levels of 26 S Proteasome Subunits in Yeast
1999
cDNA cloning of p42, a shared subunit of two proteasome regulatory proteins, reveals a novel member of the AAA protein family
1996
The 1.9 Å Structure of a Proteasome-11S Activator Complex and Implications for Proteasome-PAN/PA700 Interactions
2005
Gettin’ down with ubiquitin: turning off cell-surface receptors, transporters and channels
1999
Identification of a novel ubiquitin-conjugating enzyme involved in mitotic cyclin degradation
1996
Structural and functional effects of PA700 and modulator protein on proteasomes 1 1Edited by W. Baumeister
1997
The Ubiquitin System and the N-End Rule Pathway
2000
Multiubiquitin Chain Receptors Define a Layer of Substrate Selectivity in the Ubiquitin-Proteasome System
2004
Cotranslational Ubiquitination of Cystic Fibrosis Transmembrane Conductance Regulator in Vitro
1998
Effects of Major‐Histocompatibility‐Complex‐Encoded Subunits on the Peptidase and Proteolytic Activities of Human 20S Proteasomes
1996
Ubiquitin C-Terminal Hydrolase Is an Immediate-Early Gene Essential for Long-Term Facilitation in Aplysia
1997 StandoutNobel
Oxidants, oxidative stress and the biology of ageing
2000 StandoutNature
Ubiquitin Lys63 is involved in ubiquitination of a yeast plasma membrane protein
1997
The Logic of the 26S Proteasome
2017
The measurement of ubiquitin and ubiquitinated proteins
1999
Loss of autophagy in the central nervous system causes neurodegeneration in mice
2006 StandoutNature
Structure of 20S proteasome from yeast at 2.4Å resolution
1997 StandoutNatureNobel
Novel Multiubiquitin Chain Linkages Catalyzed by the Conjugating Enzymes E2EPF and RAD6 Are Recognized by 26 S Proteasome Subunit 5
1996
A Function for Monoubiquitination in the Internalization of a G Protein–Coupled Receptor
1998
Ump1p Is Required for Proper Maturation of the 20S Proteasome and Becomes Its Substrate upon Completion of the Assembly
1998
Recognition of the polyubiquitin proteolytic signal
2000
Endosome maturation
2011 Standout
Molecular cloning and expression of subunit 12: a non‐MCP and non‐ATPase subunit of the 26 S protease
1995
Regulation of transcription factor NF KAPPA B in immune senescence
1998
Proteasome Activators
2011
KEKE motifs
1994
The Mechanistic Links Between Proteasome Activity, Aging and Agerelated Diseases
2014
The pad1 + Gene Encodes a Subunit of the 26 S Proteasome in Fission Yeast
1998
Regulatory subunit interactions of the 26S proteasome, a complex problem
2000
Hybrid Proteasomes
2000
Removing the Vertebrate-Specific TBP N Terminus Disrupts Placental β2m-Dependent Interactions with the Maternal Immune System
2002 StandoutNobel
A surprising simplicity to protein folding
2000 StandoutNatureNobel
Self-compartmentalizing proteases
1997
A gated channel into the proteasome core particle.
2000
Global quantification of mammalian gene expression control
2011 StandoutNature
Specificity of the Ubiquitin Isopeptidase in the PA700 Regulatory Complex of 26 S Proteasomes
1997
The ubiquitin system
1997
Recognition of Misfolding Proteins by PA700, the Regulatory Subcomplex of the 26 S Proteasome
2000
cDNA Cloning and Functional Analysis of the p97 Subunit of the 26S Proteasome, a Polypeptide Identical to the Type‐1 Tumor‐Necrosis‐Factor‐Receptor‐Associated Protein‐2/55.11
1996
Proteins containing the UBA domain are able to bind to multi-ubiquitin chains
2001
Identification of a novel ubiquitin conjugation motif, required for ligand-induced internalization of the growth hormone receptor
1999
The proteasome 11S regulator subunit REGα (PA28α) is a heptamer
1997
A ubiquitin-like system mediates protein lipidation
2000 StandoutNatureNobel
Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression
2019 StandoutNobel
A Subcomplex of the Proteasome Regulatory Particle Required for Ubiquitin-Conjugate Degradation and Related to the COP9-Signalosome and eIF3
1998
Mapping the ubiquitin‐binding domains in the p54 regulatory complex subunit of the Drosophila 26S protease
1997
New insights into proteasome function: from archaebacteria to drug development
1995
Peptide antigen production by the proteasome: complexity provides efficiency
1996
Molecular cloning and expression of subunit 9 of the 26S proteasome
1997
Characterization of 26S proteasome α- and β-type and ATPase subunits from spinach and their expression during early stages of seedling development
1997
Apg16p is required for the function of the Apg12p–Apg5p conjugate in the yeast autophagy pathway
1999 StandoutNobel
Characterization of Two Polyubiquitin Binding Sites in the 26 S Protease Subunit 5a
1998
Identification of a 26S Proteasome-Associated UCH in Fission Yeast
2000
Caspase Activation Inhibits Proteasome Function during Apoptosis
2004 StandoutNobel
The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins
2000
Mts4, a Non-ATPase Subunit of the 26 S Protease in Fission Yeast Is Essential for Mitosis and Interacts Directly with the ATPase Subunit Mts2
1997
Inhibition of ubiquitin/proteasome-dependent protein degradation by the Gly-Ala repeat domain of the Epstein–Barr virus nuclear antigen 1
1997 StandoutNobel
Arabidopsis MBP1 gene encodes a conserved ubiquitin recognition component of the 26S proteasome.
1996
The Regulatory Complex of Drosophila melanogaster 26s Proteasomes
2000
Coping with Protein Quality Control Failure
2017
The Hydrophobic Effect Contributes to Polyubiquitin Chain Recognition
1998
Degradation of subunits of the Sec61p complex, an integral component of the ER membrane, by the ubiquitin-proteasome pathway.
1996
The mouse and human genes encoding the recognition component of the N-end rule pathway
1998 StandoutNobel
PEST sequences and regulation by proteolysis
1996
Differential Effects of Ubiquitin Aldehyde on Ubiquitin and ATP-Dependent Protein Degradation
1996
Pleiotropic Defects Caused by Loss of the Proteasome-Interacting Factors Rad23 and Rpn10 of Saccharomyces cerevisiae
1999
Architecture of an RNA Polymerase II Transcription Pre-Initiation Complex
2013 StandoutScienceNobel
Degradation of Proteins with Acetylated Amino Termini by the Ubiquitin System
1989 StandoutScienceNobel
Multiubiquitin Chain Binding Subunit MCB1 (RPN10) of the 26S Proteasome Is Essential for Developmental Progression in Physcomitrella patens
1999
The Regulatory Particle of the Saccharomyces cerevisiae Proteasome
1998
The 26S Proteasome: A Molecular Machine Designed for Controlled Proteolysis
1999 Standout
Cells adapted to the proteasome inhibitor 4-hydroxy- 5-iodo-3-nitrophenylacetyl-Leu-Leu-leucinal-vinyl sulfone require enzymatically active proteasomes for continued survival
2001
Rad23 Promotes the Targeting of Proteolytic Substrates to the Proteasome
2002
A Ubiquitin Mutant with Specific Defects in DNA Repair and Multiubiquitination
1995
Analysis of mammalian 20S proteasome biogenesis: the maturation of beta-subunits is an ordered two-step mechanism involving autocatalysis.
1996 Nobel
Mechanism of Ubiquitin Conjugating Enzyme E2-230K: Catalysis Involving a Thiol Relay?
1996
Regulation of Receptor Fate by Ubiquitination of Activated β 2 -Adrenergic Receptor and β-Arrestin
2001 StandoutScienceNobel
Two distinct classes of Ran-binding sites on the nucleoporin Nup-358
1999 StandoutNobel
Potential Immunocompetence of Proteolytic Fragments Produced by Proteasomes before Evolution of the Vertebrate Immune System
1997 StandoutNobel
One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA
2021 StandoutNobel
Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach
2012
Formation of Proteasome−PA700 Complexes Directly Correlates with Activation of Peptidase Activity
1998
ATG Systems from the Protein Structural Point of View
2009 StandoutNobel
Surface hydrophobic residues of multiubiquitin chains essential for proteolytic targeting.
1996
Yeast counterparts of subunits S5a and p58 (S3) of the human 26S proteasome are encoded by two multicopy suppressors of nin1-1.
1997
Regulated degradation of the transcription factor Gcn4.
1994
Dominant-negative cyclin-selective ubiquitin carrier protein E2-C/UbcH10 blocks cells in metaphase
1997 StandoutNobel
Identification of a phylogenetically conserved Sug1 CAD family member that is differentially expressed in the mouse nervous system
1997
Molecular Chaperones in the Cytosol: from Nascent Chain to Folded Protein
2002 StandoutScience
Accurate protein structure modeling using sparse NMR data and homologous structure information
2012 StandoutNobel
Proteasomes in the archaea: from structure to function
2000
Inhibition of the 26 S Proteasome by Polyubiquitin Chains Synthesized to Have Defined Lengths
1997
Subcellular distribution of proteasomes implicates a major location of protein degradation in the nuclear envelope-ER network in yeast
1998
Intracellular Functions of N-Linked Glycans
2001 StandoutScience
The Multiubiquitin-Chain-Binding Protein Mcb1 Is a Component of the 26S Proteasome in Saccharomyces cerevisiae and Plays a Nonessential, Substrate-Specific Role in Protein Turnover
1996
Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway.
1995 StandoutNobel
UBIQUITIN-DEPENDENT PROTEIN DEGRADATION
1996
Substrate Binding and Catalysis by Ubiquitin C-Terminal Hydrolases: Identification of Two Active Site Residues
1996
UBIQUITIN AND THE CONTROL OF PROTEIN FATE IN THE SECRETORY AND ENDOCYTIC PATHWAYS
1998
Roles of Ubiquitinylation in Proteolysis and Cellular Regulation
1995
A novel protein complex involved in signal transduction possessing similarities to 26S proteasome subunits
1998
Subcellular localization of proteasomes and their regulatory complexes in mammalian cells
2000
Ubiquitin Aldehyde Increases Adenosine Triphosphate–Dependent Proteolysis of Hemoglobin α-Subunits in β-Thalassemic Hemolysates
1997
DEGRADATION OF CELL PROTEINS AND THE GENERATION OF MHC CLASS I-PRESENTED PEPTIDES
1999
The Ubiquitin-Proteasome Pathway and Its Role in Cancer
2005
A Proteasome Cap Subunit Required for Spindle Pole Body Duplication in Yeast
1997
THE PROTEASOME
1999 Nobel
Analysis of a Gene Encoding Rpn10 of the Fission Yeast Proteasome Reveals That the Polyubiquitin-binding Site of This Subunit Is Essential When Rpn12/Mts3 Activity Is Compromised
2000
HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53
2003 StandoutNobel
Degradation of Ornithine Decarboxylase by the Mammalian and Yeast 26S Proteasome Complexes Requires all the Components of the Protease
1995 StandoutNobel
Chaperone rings in protein folding and degradation
1999
Basal and human papillomavirus E6 oncoprotein-induced degradation of Myc proteins by the ubiquitin pathway
1998 StandoutNobel
MECHANISMS OF MHC CLASS I–RESTRICTED ANTIGEN PROCESSING
1998
ANTIGEN PROCESSING AND PRESENTATION BY THE CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX
1996
At the crossroads of cell biology and immunology: DRiPs and other sources of peptide ligands for MHC class I molecules
2001
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Functional reconstitution of human eukaryotic translation initiation factor 3 (eIF3)
2011 StandoutNobel
In vivo disassembly of free polyubiquitin chains by yeast Ubp14 modulates rates of protein degradation by the proteasome
1997
Physical association of ubiquitin ligases and the 26S proteasome
2000
THE UBIQUITIN SYSTEM
1998 StandoutNobel
Autophagy as a Regulated Pathway of Cellular Degradation
2000 StandoutScience
Altered ubiquitination and stability of aquaporin-1 in hypertonic stress
2001 StandoutNobel
Yeast Cycloheximide-resistantcrlMutants Are Proteasome Mutants Defective in Protein Degradation
1997
Multiple Click-Selective tRNA Synthetases Expand Mammalian Cell-Specific Proteomics
2018 StandoutNobel
Novel Regulation of the Helix-Loop-Helix Protein Id1 by S5a, a Subunit of the 26 S Proteasome
1997
Scanning the human proteome for calmodulin-binding proteins
2005 StandoutNobel
Molecular Cloning and Expression of a 26 S Protease Subunit Enriched in Dileucine Repeats
1995
SUMO-1 Modification and Its Role in Targeting the Ran GTPase-activating Protein, RanGAP1, to the Nuclear Pore Complex
1998 StandoutNobel
The Axial Channel of the Proteasome Core Particle Is Gated by the Rpt2 ATPase and Controls Both Substrate Entry and Product Release
2001
Targeting of substrates to the 26S proteasome
1997
The N-end rule: functions, mysteries, uses.
1996
Proteasomal Proteomics: Identification of Nucleotide-sensitive Proteasome-interacting Proteins by Mass Spectrometric Analysis of Affinity-purified Proteasomes
2000
CDNA cloning of p112, the largest regulatory subunit of the human 26s proteasome, and functional analysis of its yeast homologue, sen3p.
1996
A mutant deubiquitinating enzyme (Ubp-M) associates with mitotic chromosomes and blocks cell division
1999
Autophagy in Health and Disease: A Double-Edged Sword
2004 StandoutScience
Works of Vicença Ustrell being referenced
Human lymphoblast and erythrocyte multicatalytic proteases: differential peptidase activities and responses to the 11S regulator
1995
The Axial Channel of the 20S Proteasome Opens Upon Binding of the PA200 Activator
2005
PA200, a nuclear proteasome activator involved in DNA repair
2002
A Protein Interaction Network for Ecm29 Links the 26 S Proteasome to Molecular Motors and Endosomal Components
2010
The proteasome activator 11 S REG (PA28) and Class I antigen presentation
1999
The proteasome activator 11 S REG (PA28) and Class I antigen presentation
2000
A 26 S protease subunit that binds ubiquitin conjugates.
1994
Effects of interferon gamma and major histocompatibility complex-encoded subunits on peptidase activities of human multicatalytic proteases.
1995