Citation Impact
Citing Papers
Identification of Ubiquitin Ligases Required for Skeletal Muscle Atrophy
2001 StandoutScience
TFEB Links Autophagy to Lysosomal Biogenesis
2011 StandoutScience
Silencing of Epidermal Growth Factor Receptor Suppresses Hypoxia-Inducible Factor-2–Driven VHL −/− Renal Cancer
2005
Infection, inflammation, height, and longevity
2005 Standout
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
Expression of the ubiquitin-proteasome pathway and muscle loss in experimental cancer cachexia
2005
Foxo Transcription Factors Induce the Atrophy-Related Ubiquitin Ligase Atrogin-1 and Cause Skeletal Muscle Atrophy
2004 Standout
Molecular pathways leading to loss of skeletal muscle mass in cancer cachexia – can findings from animal models be translated to humans?
2016
The JNK MAP kinase pathway contributes to the development of endotoxin-induced diaphragm caspase activation
2009
mTOR Signaling in Growth Control and Disease
2012 Standout
Indomethacin and ibuprofen preserve gastrocnemius muscle mass in mice bearing the colon‐26 adenocarcinoma
2004
The Ubiquitin Proteasome System in Neurodegenerative Diseases
2003 StandoutNobel
Determinants of Nuclear and Cytoplasmic Ubiquitin-mediated Degradation of MyoD
2003 StandoutNobel
Regulation of V2 Vasopressin Receptor Degradation by Agonist-promoted Ubiquitination
2003 StandoutNobel
A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
2012 StandoutNature
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
2003 StandoutNobel
Ubiquitin-Proteasome-mediated Degradation of Id1 Is Modulated by MyoD
2004 StandoutNobel
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
The molecular basis of skeletal muscle atrophy
2004
IKKβ/NF-κB Activation Causes Severe Muscle Wasting in Mice
2004
Management of muscle wasting in cancer-associated cachexia
2001
Ca2+-free Calmodulin and Calmodulin Damaged byin Vitro Aging Are Selectively Degraded by 26 S Proteasomes without Ubiquitination
2000
Cancer cachexia: Developing multimodal therapy for a multidimensional problem
2008
Indomethacin preserves muscle mass and reduces levels of E3 ligases and TNF receptor type 1 in the gastrocnemius muscle of tumor‐bearing mice
2004
Dystrophin glycoprotein complex dysfunction: A regulatory link between muscular dystrophy and cancer cachexia
2005
Myofibrillar Proteolysis in Chick Myotubes during Oxidative Stress
2004
Mechanisms for Generating the Autonomous cAMP-Dependent Protein Kinase Required for Long-Term Facilitation in Aplysia
1999 StandoutNobel
The Nuclear Ubiquitin-Proteasome System Degrades MyoD
2001 StandoutNobel
Autophagy: Renovation of Cells and Tissues
2011 Standout
Molecular Regulation of Muscle Cachexia: It May Be More Than the Proteasome
2002
Cancer-associated cachexia
2018 Standout
Protein surveillance machinery in brains with spinocerebellar ataxia type 3: Redistribution and differential recruitment of 26S proteasome subunits and chaperones to neuronal intranuclear inclusions
2002
FoxO3 Coordinately Activates Protein Degradation by the Autophagic/Lysosomal and Proteasomal Pathways in Atrophying Muscle Cells
2007
Altered responses in skeletal muscle protein turnover during aging in anabolic and catabolic periods
2005
Skeletal muscle dysfunction in critical care: Wasting, weakness, and rehabilitation strategies
2010
Protein degradation and protection against misfolded or damaged proteins
2003 StandoutNature
Processing of p105 Is Inhibited by Docking of p50 Active Subunits to the Ankyrin Repeat Domain, and Inhibition Is Alleviated by Signaling via the Carboxyl-terminal Phosphorylation/ Ubiquitin-Ligase Binding Domain
2001 StandoutNobel
Disruption of Fnip1 Reveals a Metabolic Checkpoint Controlling B Lymphocyte Development
2012 StandoutNobel
Artificial hydrolase based on carbon nanotubes conjugated with peptides
2016
Molecular chaperones in protein folding and proteostasis
2011 StandoutNature
Cachexia in cancer patients
2002
Inhibitors of the proteasome reduce the accelerated proteolysis in atrophying rat skeletal muscles.
1997
Understanding the Odd Science of Aging
2005 Standout
Growth Differentiation Factor 11 Is a Circulating Factor that Reverses Age-Related Cardiac Hypertrophy
2013 Standout
Impairment of proteasome structure and function in aging
2002
Ubiquitin-dependent Destruction of Topoisomerase I Is Stimulated by the Antitumor Drug Camptothecin
1997
Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress
2010
Sarcopenia
2019 Standout
Functional Disability 5 Years after Acute Respiratory Distress Syndrome
2011 Standout
Pathways of muscle protein breakdown in injury and sepsis
1999
The Proteasome
2001
The ubiquitin system: pathogenesis of human diseases and drug targeting
2004 StandoutNobel
Increased expression of proteasome subunits in skeletal muscle of cancer patients with weight loss
2004
Reactive oxygen species have a causal role in multiple forms of insulin resistance
2006 StandoutNature
Intracellular Proteinases of Invertebrates: Calcium-Dependent and Proteasome/Ubiquitin-Dependent Systems
1998
Mechanisms for Insulin Resistance: Common Threads and Missing Links
2012 Standout
Inhibition of Stat3 Activation Suppresses Caspase-3 and the Ubiquitin-Proteasome System, Leading to Preservation of Muscle Mass in Cancer Cachexia
2015
AKT/PKB Signaling: Navigating the Network
2017 Standout
Determinants of Disuse-Induced Skeletal Muscle Atrophy: Exercise and Nutrition Countermeasures to Prevent Protein Loss
2006
TMC-86A, B and TMC-96, New Proteasome Inhibitors from Streptomyces sp. TC 1084 and Saccharothrix sp. TC 1094. I. Taxonomy, Fermentation, Isolation, and Biological Activities.
1999
RGS4 Is Arginylated and Degraded by the N-end Rule Pathway in Vitro
2000
Reversal of Cancer Cachexia and Muscle Wasting by ActRIIB Antagonism Leads to Prolonged Survival
2010
Adaptation of the ubiquitin-proteasome proteolytic pathway in cancer cachexia
1999
The Tumor Suppressor Protein p16 and the Human Papillomavirus Oncoprotein-58 E7 Are Naturally Occurring Lysine-less Proteins That Are Degraded by the Ubiquitin System
2004 StandoutNobel
Clinical Classification of Cancer Cachexia: Phenotypic Correlates in Human Skeletal Muscle
2014
TMC-95A, B, C, and D, Novel Proteasome Inhibitors Produced by Apiospora montagnei Sacc. TC 1093. Taxonomy, Production, Isolation, and Biological Activities.
2000
Frailty in elderly people
2013 Standout
What do we really know about the ubiquitin-proteasome pathway in muscle atrophy?
2001
The ubiquitin system
2000 StandoutNobel
Cancer cachexia is regulated by selective targeting of skeletal muscle gene products
2004
Coordinated patterns of gene expression for substrate and energy metabolism in skeletal muscle of diabetic mice
2002
Sepsis stimulates release of myofilaments in skeletal muscle by a calcium‐dependent mechanism
1999
Regulation of Muscle Protein Degradation
2004
TNF‐α increases ubiquitin‐conjugating activity in skeletal muscle by up‐regulating UbcH2/E2 20k
2003
Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy
2001
Burn injury causes mitochondrial dysfunction in skeletal muscle
2005
Protein Synthesis upon Acute Nutrient Restriction Relies on Proteasome Function
2005 Science
Cancer cachexia is regulated by selective targeting of skeletal muscle gene products
2004
Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression
2004 Standout
The Calpain System
2003 Standout
Kinase requirements in human cells: III. Altered kinase requirements inVHL−/− cancer cells detected in a pilot synthetic lethal screen
2008 StandoutNobel
Spermidine in health and disease
2018 StandoutScience
Muscle mitohormesis promotes cellular survival via serine/glycine pathway flux
2014
Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes (II)
2018 Standout
Ubiquitin-mediated proteolysis: biological regulation via destruction
2000 StandoutNobel
Insulin Resistance Accelerates Muscle Protein Degradation: Activation of the Ubiquitin-Proteasome Pathway by Defects in Muscle Cell Signaling
2006
Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs
2005 Standout
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role ofPGC1andNRF1
2003 Standout
Chronic contractile activity upregulates the proteasome system in rabbit skeletal muscle
2000
Altered Activity, Social Behavior, and Spatial Memory in Mice Lacking the NTAN1p Amidase and the Asparagine Branch of the N-End Rule Pathway
2000
Impact of Natural Products on Developing New Anti-Cancer Agents
2009 Standout
HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53
2003 StandoutNobel
Autophagy and Metabolism
2010 StandoutScience
Impaired Degradation of Mutant α-Synuclein by Chaperone-Mediated Autophagy
2004 StandoutScience
Signaling mechanism of tumor cell‐induced up‐regulation of E3 ubiquitin ligase UBR2
2013
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Protacs: Chimeric molecules that target proteins to the Skp1–Cullin–F box complex for ubiquitination and degradation
2001 Standout
Mechanisms accelerating muscle atrophy in catabolic diseases.
2000
Scanning the human proteome for calmodulin-binding proteins
2005 StandoutNobel
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
PGC-1α protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription
2006
Confinement-Controlled, Either syn- or anti-Selective Catalytic Asymmetric Mukaiyama Aldolizations of Propionaldehyde Enolsilanes
2021 StandoutNobel
Relevance of Weak Hydrogen Bonds in the Conformation of Organic Compounds and Bioconjugates: Evidence from Recent Experimental Data and High-Levelab InitioMO Calculations
2010
Impairment of the Ubiquitin-Proteasome System by Protein Aggregation
2001 StandoutScience
Works of Vered Solomon being referenced
Muscle Protein Breakdown and the Critical Role of the Ubiquitin-Proteasome Pathway in Normal and Disease States
1999
Importance of the ATP-Ubiquitin-Proteasome Pathway in the Degradation of Soluble and Myofibrillar Proteins in Rabbit Muscle Extracts
1996
The N-end Rule Pathway Catalyzes a Major Fraction of the Protein Degradation in Skeletal Muscle
1998
Insulin Suppresses the Increased Activities of Lysosomal Cathepsins and Ubiquitin Conjugation System in Burn-Injured Rats
2000
Antiproteolytic Action of Insulin in Burn-Injured Rats
2002
Regulation of Protein Catabolism by Muscle-Specific and Cytokine-Inducible Ubiquitin Ligase E3α-II during Cancer Cachexia
2004
A new model of cancer cachexia: contribution of the ubiquitin-proteasome pathway
1999
Ubiquitin conjugation by the N-end rule pathway and mRNAs for its components increase in muscles of diabetic rats
1999
Rates of ubiquitin conjugation increase when muscles atrophy, largely through activation of the N-end rule pathway
1998
Mapping glycoside hydrolase substrate subsites by isothermal titration calorimetry
2004