Citation Impact
Citing Papers
Twist Transcriptionally Up-regulates AKT2 in Breast Cancer Cells Leading to Increased Migration, Invasion, and Resistance to Paclitaxel
2007
Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic
2005
In Vivo Role of INPP4B in Tumor and Metastasis Suppression through Regulation of PI3K–AKT Signaling at Endosomes
2015
Pten Loss in the Mouse Thyroid Causes Goiter and Follicular Adenomas: Insights into Thyroid Function and Cowden Disease Pathogenesis
2007
mTOR Inhibition Induces Upstream Receptor Tyrosine Kinase Signaling and Activates Akt
2006 Standout
MK-2206, an Allosteric Akt Inhibitor, Enhances Antitumor Efficacy by Standard Chemotherapeutic Agents or Molecular Targeted Drugs In vitro and In vivo
2010 Standout
The oncogenic properties of mutant p110α and p110β phosphatidylinositol 3-kinases in human mammary epithelial cells
2005
High Frequency of Mutations of the PIK3CA Gene in Human Cancers
2004 StandoutScience
TOR Signaling in Growth and Metabolism
2006 Standout
The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas
2007 Standout
The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines.
2003
2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer
2015 Standout
Uncommon Mutation, but Common Amplifications, of thePIK3CAGene in Thyroid Tumors
2005
Molecular imaging in drug development
2008 Standout
Mechanisms of type-I- and type-II-interferon-mediated signalling
2005 Standout
Thyroid cancer
2016 Standout
The tor pathway: a target for cancer therapy
2004 Standout
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
2006 Standout
AKT/PKB Signaling: Navigating Downstream
2007 Standout
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Mammalian phosphoinositide kinases and phosphatases
2009 StandoutNobel
ENDOCRINE TUMOURS: Approach to the patient with advanced differentiated thyroid cancer
2011
The phosphatidylinositol 3-Kinase–AKT pathway in human cancer
2002 Standout
TGF-β-induced EMT: mechanisms and implications for fibrotic lung disease
2007 Standout
Activation of AKT Kinases in Cancer: Implications for Therapeutic Targeting
2005
Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways
2005 StandoutNobel
Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer
2003 Standout
Complex networks orchestrate epithelial–mesenchymal transitions
2006 Standout
Temsirolimus, Interferon Alfa, or Both for Advanced Renal-Cell Carcinoma
2007 Standout
Exploiting the PI3K/AKT Pathway for Cancer Drug Discovery
2005 Standout
Congenital Heart Disease and Neurodevelopment: Clinical Manifestations, Genetics, Mechanisms, and Implications
2017
Targeting the phosphoinositide 3-kinase pathway in cancer
2009 Standout
Case fatality rate and associated factors in patients with 22q11 microdeletion syndrome: a retrospective cohort study
2014
Prospective randomized controlled multi-centre trial of cuffed or uncuffed endotracheal tubes in small children
2009
Upstream and downstream of mTOR
2004 Standout
Targeting cancer with small molecule kinase inhibitors
2008 Standout
The effect Akt2 deletion on tumor development in Pten+/− mice
2011
Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
2007 StandoutNature
Progress in molecular-based management of differentiated thyroid cancer
2013
Increased activated Akt expression in renal cell carcinomas and prognosis
2008
Metabolomics: the apogee of the omics trilogy
2012 Standout
Mechanisms of drug combinations: interaction and network perspectives
2009 Standout
The roles of PTEN in development, physiology and tumorigenesis in mouse models: a tissue-by-tissue survey
2008 StandoutNobel
Portrait of PTEN: Messages from mutant mice
2008 StandoutNobel
Beyond Radioiodine: A Review of Potential New Therapeutic Approaches for Thyroid Cancer
2003
European consensus for the management of patients with differentiated thyroid carcinoma of the follicular epithelium
2006 Standout
PI3K/Akt signalling pathway and cancer
2003 Standout
The IGF-1/PI3K/Akt Pathway Prevents Expression of Muscle Atrophy-Induced Ubiquitin Ligases by Inhibiting FOXO Transcription Factors
2004 Standout
Molecular alterations in apoptotic pathways after PKB/Akt-mediated chemoresistance in NCI H460 cells
2004
22q11.2 Deletion syndrome is associated with perioperative outcome in tetralogy of Fallot
2013
Molecular mechanisms of carbonic anhydrase IX‐mediated pH regulation under hypoxia
2008 StandoutNobel
The STATs of cancer — new molecular targets come of age
2004 Standout
AKT/PKB Signaling: Navigating the Network
2017 Standout
Essential roles of PI(3)K–p110β in cell growth, metabolism and tumorigenesis
2008 Nature
Targeting PI3K signalling in cancer: opportunities, challenges and limitations
2009 Standout
22q11.2 deletion syndrome
2015 Standout
Molecular mechanisms involved in differentiated thyroid cancer invasion and metastasis
2006
Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression
2004 Standout
A novel form of constitutively active farnesylated Akt1 prevents mammary epithelial cells from anoikis and suppresses chemotherapy-induced apoptosis
2002
Apoptosome dysfunction in human cancer
2004
The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
2008 Standout
Management Guidelines for Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Taskforce
2006 Standout
Medullary Thyroid Cancer: Management Guidelines of the American Thyroid Association
2009 Standout
Clinical Trials for Progressive Differentiated Thyroid Cancer: Patient Selection, Study Design, and Recent Advances
2009
2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack: A Guideline From the American Heart Association/American Stroke Association
2021 Standout
Akt1 Activation Can Augment Hypoxia-Inducible Factor-1α Expression by Increasing Protein Translation through a Mammalian Target of Rapamycin–Independent Pathway
2006
Conditional loss of PTEN leads to testicular teratoma and enhances embryonic germ cell production
2003 StandoutNobel
RET as a Diagnostic and Therapeutic Target in Sporadic and Hereditary Endocrine Tumors
2006
Apoptosis: A Review of Programmed Cell Death
2007 Standout
Activation of phosphatidylinositol 3-kinase signaling by a mutant thyroid hormone β receptor
2006
Genetic Alterations and Their Relationship in the Phosphatidylinositol 3-Kinase/Akt Pathway in Thyroid Cancer
2007
Augmentation of sodium butyrate-induced apoptosis by phosphatidylinositol 3'-kinase inhibition in the KM20 human colon cancer cell line.
2002
Iterative in Situ Click Chemistry Assembles a Branched Capture Agent and Allosteric Inhibitor for Akt1
2011 StandoutNobel
Activation of Akt and eIF4E Survival Pathways by Rapamycin-Mediated Mammalian Target of Rapamycin Inhibition
2005 Standout
Thyroid Hormone Regulation of Metabolism
2014 Standout
pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner
2016 StandoutScienceNobel
Guidelines for the management of thyroid cancer
2014 Standout
Phosphatidylinositol 3-Kinase/Akt and Ras/Raf-Mitogen-Activated Protein Kinase Pathway Mutations in Anaplastic Thyroid Cancer
2007
Part 14: Pediatric Advanced Life Support
2010 Standout
A Phase I and Pharmacokinetic Study of Temsirolimus (CCI-779) Administered Intravenously Daily for 5 Days Every 2 Weeks to Patients with Advanced Cancer
2006
Works of Vera Bernet being referenced
Cerebral lesions on magnetic resonance imaging correlate with preoperative neurological status in neonates undergoing cardiopulmonary bypass surgery
2013
Klinische Evaluation eines Überdruckventils für Kindertuben mit Cuff
2009
Children with genetic disorders undergoing open-heart surgery: Are they at increased risk for postoperative complications?*
2010
Overexpression and overactivation of Akt in thyroid carcinoma.
2001