Citation Impact
Citing Papers
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α
2007 Standout
H 2 S as a Physiologic Vasorelaxant: Hypertension in Mice with Deletion of Cystathionine γ-Lyase
2008 StandoutScience
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
2014 StandoutNobel
Redox mechanisms in hepatic chronic wound healing and fibrogenesis
2008
A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension
2019 StandoutNobel
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Hypoxia and chronic lung disease
2007
LTRPC2 Ca2+-Permeable Channel Activated by Changes in Redox Status Confers Susceptibility to Cell Death
2002
Primary Pulmonary Hypertension
2000
Acute Oxygen-Sensing Mechanisms
2005
Oxygen sensing and signal transduction in hypoxic pulmonary vasoconstriction
2015
Sustained pulmonary hypertension and right ventricular hypertrophy after chronic hypoxia in mice with congenital deficiency of nitric oxide synthase 3.
1998
Valvular Heart Disease Associated with Fenfluramine–Phentermine
1997 Standout
Sirtuin-7 Inhibits the Activity of Hypoxia-inducible Factors
2013 StandoutNobel
Cyclic GMP-dependent Protein Kinase Activates Cloned BKCa Channels Expressed in Mammalian Cells by Direct Phosphorylation at Serine 1072
1999
Treatment of Pulmonary Arterial Hypertension
2004 Standout
Differences in STIM1 and TRPC expression in proximal and distal pulmonary arterial smooth muscle are associated with differences in Ca2+responses to hypoxia
2008
Cancer Cell Metabolism: Warburg and Beyond
2008 Standout
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
The Protective Effects of Estrogen on the Cardiovascular System
1999 Standout
Chronic hypoxia inhibits Kv channel gene expression in rat distal pulmonary artery
2005
Cellular and molecular pathobiology of pulmonary arterial hypertension
2004 Standout
β2-Adrenergic Receptor-induced p38 MAPK Activation Is Mediated by Protein Kinase A Rather than by Gi or Gβγ in Adult Mouse Cardiomyocytes
2000 StandoutNobel
A Mitochondria-K+ Channel Axis Is Suppressed in Cancer and Its Normalization Promotes Apoptosis and Inhibits Cancer Growth
2007
NO: COPD and beyond
1997
Ca2+Channels and Chronic Hypoxia
2006
Primary pulmonary hypertension
2003
High-Altitude Pulmonary Edema: From Exaggerated Pulmonary Hypertension to a Defect in Transepithelial Sodium Transport
1999
Acute hypoxia increases intracellular [Ca2+] in pulmonary arterial smooth muscle by enhancing capacitative Ca2+ entry
2005
Pulmonary Vasoconstriction, Oxygen Sensing, and the Role of Ion Channels
1998
Hypoxia Induces Cell-Specific Changes in Gene Expression in Vascular Wall Cells: Implications for Pulmonary Hypertension
1999
Blinded by the Light: The Growing Complexity of p53
2009 Standout
HIF hydroxylation and the mammalian oxygen-sensing pathway
2003 StandoutNobel
TRP channels as cellular sensors
2003 StandoutNature
Glial and neuronal control of brain blood flow
2010 StandoutNature
Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1α-Kv1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer
2007
Cellular and Molecular Basis of Pulmonary Arterial Hypertension
2009
Effects of Iron Supplementation and Depletion on Hypoxic Pulmonary Hypertension
2009 StandoutNobel
The Metabolic Basis of Pulmonary Arterial Hypertension
2014
The Pathogenesis of Vasodilatory Shock
2001
Imaging Dynamic Redox Changes in Mammalian Cells with Green Fluorescent Protein Indicators
2004 StandoutNobel
High-Altitude Illness
2001 Standout
Long-term Pharmacotherapy of Obesity 2000
2001
HIF-1 Regulates Cytochrome Oxidase Subunits to Optimize Efficiency of Respiration in Hypoxic Cells
2007 StandoutNobel
Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α
1999 StandoutNobel
Smooth muscle cell expression of type I cyclic GMP-dependent protein kinase is suppressed by continuous exposure to nitrovasodilators, theophylline, cyclic GMP, and cyclic AMP.
1997
Inhibition of hypoxic pulmonary vasoconstriction by antagonists of store-operated Ca2+ and nonselective cation channels
2005
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Endothelin-1 mediates hypoxia-induced inhibition of voltage-gated K+ channel expression in pulmonary arterial myocytes
2007 StandoutNobel
Prevention of Hemodilution-Induced Inhibition of Hypoxic Pulmonary Vasoconstriction by N-Acetylcysteine in Dogs
2004
Selective pharmacological inhibition of distinct nitric oxide synthase isoforms
1996
Linkage of β1-adrenergic stimulation to apoptotic heart cell death through protein kinase A–independent activation of Ca2+/calmodulin kinase II
2003 StandoutNobel
The immunopathogenesis of sepsis
2002 StandoutNature
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
2009 Standout
Prostacyclin Synthase Expression Is Decreased in Lungs from Patients with Severe Pulmonary Hypertension
1999
Subacute Hypoxia Decreases Voltage-Activated Potassium Channel Expression and Function in Pulmonary Artery Myocytes
2004
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
2012 Standout
Hypoxia Decreases Exhaled Nitric Oxide in Mountaineers Susceptible to High-Altitude Pulmonary Edema
2001
RISK FACTORS FOR PULMONARY ARTERIAL HYPERTENSION
2001
Digoxin inhibits development of hypoxic pulmonary hypertension in mice
2012 StandoutNobel
Inhibition of voltage-gated K+currents by endothelin-1 in human pulmonary arterial myocytes
2001
Frequency modulation of Ca2+sparks is involved in regulation of arterial diameter by cyclic nucleotides
1998
Dysfunctional Voltage-Gated K + Channels in Pulmonary Artery Smooth Muscle Cells of Patients With Primary Pulmonary Hypertension
1998
Chronic hypoxia decreases KVchannel expression and function in pulmonary artery myocytes
2001
In Vivo Gene Transfer of the O 2 -Sensitive Potassium Channel Kv1.5 Reduces Pulmonary Hypertension and Restores Hypoxic Pulmonary Vasoconstriction in Chronically Hypoxic Rats
2003
Clinical iron deficiency disturbs normal human responses to hypoxia
2016 StandoutNobel
Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α
2002 StandoutNobel
Chronic hypoxia upregulates endothelial and inducible NO synthase gene and protein expression in rat lung
1996
Oxygen Sensing by Primary Cardiac Fibroblasts
2003
Hypoxia-inducible factor 1α protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations
2000 StandoutNobel
Inhibition of voltage-gated K+current in rat intrapulmonary arterial myocytes by endothelin-1
1998
Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression
2014 StandoutNobel
Pulmonary Arterial Hypertension
2006
Guanylyl Cyclases and Signaling by Cyclic GMP
2000 Standout
ET-1 modulates KCa-channel activity and arterial tension in normoxic and hypoxic human pulmonary vasculature
1998
Functional Arteries Grown in Vitro
1999 StandoutScience
An Abnormal Mitochondrial–Hypoxia Inducible Factor-1α–Kv Channel Pathway Disrupts Oxygen Sensing and Triggers Pulmonary Arterial Hypertension in Fawn Hooded Rats
2006
An endothelium-derived hyperpolarizing factor distinct from NO and prostacyclin is a major endothelium-dependent vasodilator in resistance vessels of wild-type and endothelial NO synthase knockout mice
2000
Nitric oxide regulates basal systemic and pulmonary vascular resistance in healthy humans.
1994
Endothelium‐dependent hyperpolarizations: Past beliefs and present facts
2007
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
Long-Term Treatment With Oral Sildenafil Is Safe and Improves Functional Capacity and Hemodynamics in Patients With Pulmonary Arterial Hypertension
2003
Identification of Epoxyeicosatrienoic Acids as Endothelium-Derived Hyperpolarizing Factors
1996
Effects of hypoxia in porcine pulmonary arterial myocytes: roles of KVchannel and endothelin-1
2000
Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds
2011 Standout
ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease
2006 Standout
Partial HIF-1α deficiency impairs pulmonary arterial myocyte electrophysiological responses to hypoxia
2001 StandoutNobel
Linkage of β1-adrenergic stimulation to apoptotic heart cell death through protein kinase A–independent activation of Ca2+/calmodulin kinase II
2003 StandoutNobel
Chronic hypoxia alters effects of endothelin and angiotensin on K+currents in pulmonary arterial myocytes
1999
Pharmacological and immunohistochemical evidence for a functional nitric oxide synthase system in rat peritoneal eosinophils
1997 StandoutNobel
Pulmonary Vasoconstriction and Hypertension in Mice With Targeted Disruption of the Endothelial Nitric Oxide Synthase (NOS 3) Gene
1997
Role of cGMP versus 20-HETE in the vasodilator response to nitric oxide in rat cerebral arteries
2000
Hearts From Rodents Exposed to Intermittent Hypoxia or Erythropoietin Are Protected Against Ischemia-Reperfusion Injury
2003 StandoutNobel
Dichloroacetate, a Metabolic Modulator, Prevents and Reverses Chronic Hypoxic Pulmonary Hypertension in Rats
2002
Gender Differences in Coronary Artery Diameter Involve Estrogen, Nitric Oxide, and Ca2+-Dependent K+Channels
1996
Alterations in a redox oxygen sensing mechanism in chronic hypoxia
2001
BKCachannel activation by membrane-associated cGMP kinase may contribute to uterine quiescence in pregnancy
2000
The Pharmacology of the Ductus Arteriosus
1998
Molecular basis of hypoxia-induced pulmonary vasoconstriction: role of voltage-gated K+channels
2001
Calcium - a life and death signal
1998 StandoutNature
Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2
2001 StandoutNobel
HIF-1 and human disease: one highly involved factor
2000 StandoutNobel
L-type Ca2+channels, resting [Ca2+]i, and ET-1-induced responses in chronically hypoxic pulmonary myocytes
2000
Hypoxia-inducible factor 1 is required for remote ischemic preconditioning of the heart
2013 StandoutNobel
Free Radicals in the Physiological Control of Cell Function
2002 Standout
Elevated blood pressures in mice lacking endothelial nitric oxide synthase
1996 StandoutNobel
Capacitative calcium entry and TRPC channel proteins are expressed in rat distal pulmonary arterial smooth muscle
2004
Molecular basis and function of voltage-gated K+channels in pulmonary arterial smooth muscle cells
1998
Temporal, spatial, and oxygen-regulated expression of hypoxia-inducible factor-1 in the lung
1998 StandoutNobel
Works of Václav Hampl being referenced
Hyperoxia and Recovery from Hypoxia Alter Collagen in Peripheral Pulmonary Arteries Similarly
2001
Molecular identification of the role of voltage-gated K+ channels, Kv1.5 and Kv2.1, in hypoxic pulmonary vasoconstriction and control of resting membrane potential in rat pulmonary artery myocytes.
1998
Perinatal Hypoxia Increases Hypoxic Pulmonary Vasoconstriction in Adult Rats Recovering from Chronic Exposure to Hypoxia
1990
Long-term effects of prenatal indomethacin administration on the pulmonary circulation in rats
1995
Origins of Breath Nitric Oxide in Humans
1996
NG-monomethyl-l-arginine causes nitric oxide synthesis in isolated arterial rings: Trouble in paradise
1992
Dithionite Increases Radical Formation and Decreases Vasoconstriction in the Lung
1995
Impairment of hypoxic pulmonary vasoconstriction in mice lacking the voltage‐gated potassium channel Kv1.5
2001
Chronic EDRF inhibition and hypoxia: effects on pulmonary circulation and systemic blood pressure
1993
Differential Distribution of Electrophysiologically Distinct Myocytes in Conduit and Resistance Arteries Determines Their Response to Nitric Oxide and Hypoxia
1996
Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase.
1994
Role of Endothelial-Derived Nitric Oxide in Normal and Hypertensive Pulmonary Vasculature
1994
Anorexic Agents Aminorex, Fenfluramine, and Dexfenfluramine Inhibit Potassium Current in Rat Pulmonary Vascular Smooth Muscle and Cause Pulmonary Vasoconstriction
1996
Hypoxic fetoplacental vasoconstriction in humans is mediated by potassium channel inhibition
2002
Diversity in Mitochondrial Function Explains Differences in Vascular Oxygen Sensing
2002
Increased endothelium-derived NO in hypertensive pulmonary circulation of chronically hypoxic rats
1994
Hypoxia potentiates nitric oxide synthesis and transiently increases cytosolic calcium levels in pulmonary artery endothelial cells
1995
Nebulized nitric oxide/nucleophile adduct reduces chronic pulmonary hypertension.
1996