Citation Impact
Citing Papers
Genetic Dissection of the Amyloid Precursor Protein in Developmental Function and Amyloid Pathogenesis
2010 StandoutNobel
Alzheimer's disease: synapses gone cold
2011
Altered Ribostasis: RNA-Protein Granules in Degenerative Disorders
2013
The amyloid precursor protein: beyond amyloid.
2006
Complementary and alternative therapies for Down syndrome
2005
Hippocampal Sclerosis in Older Patients: Practical Examples and Guidance With a Focus on Cerebral Age-Related TDP-43 With Sclerosis
2017
Biomolecular condensates: organizers of cellular biochemistry
2017 Standout
School based screening for hypothyroidism in Down's syndrome by dried blood spot TSH measurement
2000
A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome
2015
Alzheimer Mechanisms and Therapeutic Strategies
2012
Co‐occurring medical conditions in adults with Down syndrome: A systematic review toward the development of health care guidelines
2017
Disease-Specific Induced Pluripotent Stem Cells
2008 Standout
Proteolytic Processing of Amyloid-β Precursor Protein by Secretases Does Not Require Cell Surface Transport
2004 StandoutNobel
APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy
2005
Aβ Oligomers – a decade of discovery
2007 Standout
The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
2008 Standout
Deciphering the Molecular Basis of Memory Failure in Alzheimer's Disease
2004
Vascular dementia
2015 Standout
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Comorbidity of autistic spectrum disorders in children with Down syndrome
1999
Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy
2012 Standout
Neurobehavioral disorders in children, adolescents, and young adults with Down syndrome
2006
Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid β-peptide
2007 Standout
Genetic and host factors for dementia in Down's syndrome
2002
Longitudinal study of thyroid function in Down's syndrome in the first two decades
2005
Spreading of pathology in neurodegenerative diseases: a focus on human studies
2015
A Hundred Years of Alzheimer's Disease Research
2006
Prevalence and Trends in Obesity Among US Adults, 1999-2008
2010 Standout
Alzheimer's disease in Down syndrome: Neurobiology and risk
2007
Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo
2002 StandoutNature
Altered Metabolism of the Amyloid β Precursor Protein Is Associated with Mitochondrial Dysfunction in Down's Syndrome
2002
TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model
2015 Standout
Decoding ALS: from genes to mechanism
2016 StandoutNature
The law of mass action applied to neurodegenerative disease: a hypothesis concerning the etiology and pathogenesis of complex diseases
2004
New cross sectional stature, weight, and head circumference references for Down's syndrome in the UK and Republic of Ireland
2002
TDP-43 is a key player in the clinical features associated with Alzheimer’s disease
2014
Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates
2019 Standout
Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease
2016 Standout
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Genetics, environmental factors and the emerging role of epigenetics in neurodegenerative diseases
2008
Protein aggregation and neurodegenerative disease
2004 Standout
Cognitive deficits and associated neurological complications in individuals with Down's syndrome
2010
Dissection of Amyloid-β Precursor Protein-dependent Transcriptional Transactivation
2004 StandoutNobel
Down Syndrome: Advances in Molecular Biology and the Neurosciences
2001
Flotillin-Dependent Clustering of the Amyloid Precursor Protein Regulates Its Endocytosis and Amyloidogenic Processing in Neurons
2008 StandoutNobel
Low risk of solid tumors in persons with Down syndrome
2016
Apolipoprotein E in Alzheimer's disease and other neurological disorders
2011
Alzheimer's disease
2006 Standout
Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles
2003 Standout
Intraneuronal β-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer's Disease Mutations: Potential Factors in Amyloid Plaque Formation
2006 Standout
Dementia in Down's syndrome
2016
“New Old Pathologies”: AD, PART, and Cerebral Age-Related TDP-43 With Sclerosis (CARTS)
2016
The four ages of Down syndrome
2006
Alzheimer's Disease
2010 Standout
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
Early-Onset Alzheimer Disease
2017
A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
2015 Standout
Genetics of β-Amyloid Precursor Protein in Alzheimer's Disease
2016
The Amyloid State of Proteins in Human Diseases
2012 Standout
Three dimensions of the amyloid hypothesis: time, space and 'wingmen'
2015
Down's syndrome
2003 Standout
Oligomeric and Fibrillar Species of Amyloid-β Peptides Differentially Affect Neuronal Viability
2002 Standout
Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation
2011 StandoutNatureNobel
Health Supervision for Children With Down Syndrome
2011 Standout
Challenges of multimorbidity of the aging brain: a critical update
2014
Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization
2015 Standout
Staging TDP-43 pathology in Alzheimer’s disease
2013
The β‐Amyloid Precursor Protein (APP) and Alzheimer's Disease: Does the Tail Wag the Dog?
2002
Pathways towards and away from Alzheimer's disease
2004 StandoutNature
The Brain's Default Network
2008 Standout
Increased App Expression in a Mouse Model of Down's Syndrome Disrupts NGF Transport and Causes Cholinergic Neuron Degeneration
2006 Standout
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
2010 StandoutNobel
The amyloid hypothesis of Alzheimer's disease at 25 years
2016 Standout
Down Syndrome
2020 Standout
Population-Based Prevention of Obesity
2008
The neuropathological diagnosis of Alzheimer’s disease
2019 Standout
Endosome function and dysfunction in Alzheimer's disease and other neurodegenerative diseases
2004
TDP‐43 pathology in Alzheimer's disease, dementia with Lewy bodies and ageing
2016
A Century of Alzheimer's Disease
2006 StandoutScience
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Copper Homeostasis and Neurodegenerative Disorders (Alzheimer's, Prion, and Parkinson's Diseases and Amyotrophic Lateral Sclerosis)
2006 Standout
Three-Dimensional Structure of an Independently Folded Extracellular Domain of Human Amyloid-β Precursor Protein,
2004 StandoutNobel
The Calpain System
2003 Standout
Pharmacotherapy of Down syndrome
2018
Health care management of adults with Down syndrome.
2001
Regulation of Caenorhabditis elegans neuronal polarity by heterochronic genes
2019 StandoutNobel
Binding of F-spondin to amyloid-β precursor protein: A candidate amyloid-β precursor protein ligand that modulates amyloid-β precursor protein cleavage
2004 StandoutNobel
Axonopathy and Transport Deficits Early in the Pathogenesis of Alzheimer's Disease
2005 Science
Alzheimer's Disease: Genes, Proteins, and Therapy
2001 Standout
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
A Clinical Overview of Cholinesterase Inhibitors in Alzheimer’s Disease
2002
Alzheimer's Disease Is a Synaptic Failure
2002 StandoutScience
Characterization of Thyroid Abnormalities in a Large Cohort of Children with Down Syndrome
2017
Comorbidity of autistic spectrum disorders in children with Down syndrome
1999
Biogenesis of γ-secretase early in the secretory pathway
2007 StandoutNobel
TAR DNA‐binding protein 43 and pathological subtype of Alzheimer's disease impact clinical features
2015
Down Syndrome Disintegrative Disorder
2014
Works of V. P. Prasher being referenced
Misdiagnosis of Thyroid Disorders in Down Syndrome: Time to Re-Examine the Myth?
2004
ApoE Genotype and Alzheimer's Disease in Adults With Down Syndrome: Meta-Analysis
1997
Association of variants within APOE, SORL1, RUNX1, BACE1 and ALDH18A1 with dementia in Alzheimer's disease in subjects with Down syndrome
2010
Review of donepezil, rivastigmine, galantamine and memantine for the treatment of dementia in Alzheimer's disease in adults with Down syndrome: implications for the intellectual disability population
2004
The Extended <i>Tau</i> Haplotype and the Age of Onset of Dementia in Down Syndrome
2008
Disintegrative syndrome in young adults
2002
Long term safety and efficacy of donepezil in the treatment of dementia in Alzheimer's disease in adults with Down syndrome: open label study
2003
Seizures associated with fluoxetine therapy
1993
Fifteen-year follow-up of thyroid status in adults with Down syndrome
2011
Memantine for dementia in adults older than 40 years with Down's syndrome (MEADOWS): a randomised, double-blind, placebo-controlled trial
2012
Down Syndrome and Thyroid Disorders: A Review
1999
Patterns and severity of vascular amyloid in Alzheimer’s disease associated with duplications and missense mutations in APP gene, Down syndrome and sporadic Alzheimer’s disease
2018
An Intron 7 Polymorphism in APP Affects the Age of Onset of Dementia in Down Syndrome
2010
Brain anatomy and ageing in non-demented adults with Down's syndrome: anin vivoMRI study
2009
Molecular mapping of alzheimer‐type dementia in Down's syndrome
1998
Natural history of thyroid function in adults with Down syndrome – 10‐year follow‐up study
2006
A 24‐week, double‐blind, placebo‐controlled trial of donepezil in patients with Down syndrome and Alzheimer's disease—pilot study
2002
Significant effect of APOE epsilon 4 genotype on the risk of dementia in Alzheimer's disease and mortality in persons with Down Syndrome
2008
Brief report: Obsessive-compulsive disorder in adults with Down's Syndrome
1995
TDP-43 pathological changes in early onset familial and sporadic Alzheimer’s disease, late onset Alzheimer’s disease and Down’s Syndrome: association with age, hippocampal sclerosis and clinical phenotype
2011
Overweight and obesity amongst Down's syndrome adults
1995
Causes of age-related decline in adaptive behavior of adults with Down syndrome: differential diagnoses of dementia.
1996
Hypothyroidism Presenting as Dementia in a Person with Down Syndrome A Case Report
1993
Case Report: Challenging Behaviour in a Young Adult with Down's Syndrome and Autism
1996
Age‐specific prevalence, thyroid dysfunction and depressive symptomatology in adults with down syndrome and dementia
1995
The First Confirmed Case of Down Syndrome with Dementia with Lewy Bodies
2010
Age of onset and duration of dementia in people with down syndrome: Integration of 98 reported cases in the literature
1993
Screening of medical problems in adults with Down syndrome
1994
Reliability of diagnosing clinical hypothyroidism in adults with Down syndrome
1995
Total serum cholesterol levels and Alzheimer's dementia in patients with down syndrome
2008