Citation Impact
Citing Papers
Progressive Disruption of Cellular Protein Folding in Models of Polyglutamine Diseases
2006 Science
Prospective identification of tumorigenic breast cancer cells
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Parkinson-like syndrome induced by continuous MPTP infusion: Convergent roles of the ubiquitin-proteasome system and α-synuclein
2005 StandoutNobel
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
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Mediation of Poly(ADP-Ribose) Polymerase-1-Dependent Cell Death by Apoptosis-Inducing Factor
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Chaperone Suppression of α-Synuclein Toxicity in a Drosophila Model for Parkinson's Disease
2002 StandoutScience
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2003
Suppression of Reactive Oxygen Species and Neurodegeneration by the PGC-1 Transcriptional Coactivators
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Frailty in Older Adults: Evidence for a Phenotype
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Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation
2015 StandoutNobel
Strength and Aerobic Training Attenuate Muscle Wasting and Improve Resistance to the Development of Disability With Aging
1995
Disrupted mitochondrial electron transport function increases expression of anti-apoptotic Bcl-2 and Bcl-XL proteins in SH-SY5Y neuroblastoma and in Parkinson disease cybrid cells through oxidative stress
2000
Increased levels of lipid hydroperoxides in the parkinsonian substantia nigra: An HPLC and ESR study
1994
A Role for 12-lipoxygenase in Nerve Cell Death Caused by Glutathione Depletion
1997
Reactive Oxygen Species and the Central Nervous System
1992 Standout
α-Synuclein Promotes Mitochondrial Deficit and Oxidative Stress
2000
The Ubiquitin Proteasome System in Neurodegenerative Diseases
2003 StandoutNobel
Invited Review Free radicals and the pathobiology of brain dopamine systems
1998
Increased mitochondrial superoxide dismutase activity in Parkinson's disease but not amyotrophic lateral sclerosis motor cortex
1997
Do defecs in mitochondrial energy metabolism underlie the pathology of neurodegenerative diseases?
1993
Mitochondria: Dynamic Organelles in Disease, Aging, and Development
2006 Standout
Dysfunction of mitochondrial complex I and the proteasome: interactions between two biochemical deficits in a cellular model of Parkinson's disease
2003
Mitochondrial respiratory failure in skeletal muscle from patients with Parkinson's disease and multiple system atrophy
1994
Genetic or Pharmacological Iron Chelation Prevents MPTP-Induced Neurotoxicity In Vivo
2003
Increased Basal Ganglia Iron Levels in Huntington Disease
1999
An inhibitor of mitochondrial complex I, rotenone, inactivates proteasome by oxidative modification and induces aggregation of oxidized proteins in SH‐SY5Y cells
2003
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
1998 StandoutNature
Plasma Homocysteine as a Risk Factor for Dementia and Alzheimer's Disease
2002 Standout
Premature ageing in mice expressing defective mitochondrial DNA polymerase
2004 StandoutNature
Mitochondrial function in neurodegeneration and ageing
1992
Hydrogen peroxide mediates amyloid β protein toxicity
1994 Standout
Genetics of Parkinson's disease
1997
Proteasomal function is impaired in substantia nigra in Parkinson's disease
2001
Oxidative damage in neurodegenerative disease
1994
Proteolytic stress: A unifying concept for the etiopathogenesis of Parkinson's disease
2003
High frequency of mitochondrial complex I mutations in Parkinson’s disease and aging
2004
Mitochondrial toxins in models of neurodegenerative diseases. I: in vivo brain hydroxyl radical production during sytemic MPTP treatment or following microdialysis infusion of methylpyridinium or azide ions
1997
Oxidative stress and the pathogenesis of Parkinson's disease
1996
Hallmarks of aging: An expanding universe
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A role for mitochondria in NLRP3 inflammasome activation
2010 StandoutNature
Parkinson's Disease Is Associated with Oxidative Damage to Cytoplasmic DNA and RNA in Substantia Nigra Neurons
1999
An evaluation of the role of mitochondria in neurodegenerative diseases: mitochondrial mutations and oxidative pathology, protective nuclear responses, and cell death in neurodegeneration
1999
Altered proteasomal function due to the expression of polyglutamine-expanded truncated N-terminal huntingtin induces apoptosis by caspase activation through mitochondrial cytochrome c release
2001
On the question of apoptosis in the parkinsonian substantia nigra
1997
Decline with age of the respiratory chain activity in human skeletal muscle
1994
Mitochondrial diseases
2012
Aging, energy, and oxidative stress in neurodegenerative diseases
1995
Oxidative damage and metabolic dysfunction in Huntington's disease: Selective vulnerability of the basal ganglia
1997
Genetic aspects of Parkinson's disease
1998
Nature and cause of mitochondrial dysfunction in Huntington’s disease: focusing on huntingtin and the striatum
2010
Biological Functions of Autophagy Genes: A Disease Perspective
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Somatic mitochondrial DNA mutations in cortex and substantia nigra in aging and Parkinson’s disease
2003
Chronic systemic complex I inhibition induces a hypokinetic multisystem degeneration in rats
2003
Nrf2-induced antioxidant protection: A promising target to counteract ROS-mediated damage in neurodegenerative disease?
2008
Mitochondria, Oxidants, and Aging
2005 Standout
Mitochondrial Respiration and ATP Production Are Significantly Impaired in Striatal Cells Expressing Mutant Huntingtin
2005
Elevated reactive oxygen species and antioxidant enzyme activities in animal and cellular models of Parkinson's disease
1997
Major strain differences in response to chronic systemic administration of the mitochondrial toxin 3-nitropropionic acid in rats: implications for neuroprotection studies
2000
Platelet mitochondria function in Parkinson's disease
1992
Contributory mechanisms in the causation of neurodegenerative disorders
1993
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
Multiple Deletions Are Detectable in Mitochondrial DNA of Aging Mice
1995
Extracellular accumulation of nitric oxide, hydrogen peroxide, and glutamate in astrocytic cultures following glutathione depletion, complex I inhibition, and/or lipopolysaccharide-induced activation
2000
Mitochondrial dysfunction in neurodegenerative disorders
1998
Neurodegenerative disorders in humans: the role of glutathione in oxidative stress-mediated neuronal death
1997
Oxidative stress as a cause of nigral cell death in Parkinson's disease and incidental lewy body disease
1992
Molecular chaperones in protein folding and proteostasis
2011 StandoutNature
Oxidative stress in Parkinson's disease
2003 Standout
Dysfunction of rat forebrain astrocytes in culture alters cytokine and neurotrophic factor release
2000
High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer's disease brain
2002
α-Synuclein Cooperates with CSPα in Preventing Neurodegeneration
2005 StandoutNobel
Coenzyme Q10 and nicotinamide and a free radical spin trap protect against MPTP neurotoxicity
1995
Autophagy in Human Health and Disease
2013 Standout
Association of slow acetylator genotype for N-acetyltransferase 2 with familial Parkinson's disease
1997
Sequestration of iron by Lewy bodies in Parkinson's disease
2000
α-Synuclein: Normal Function and Role in Neurodegenerative Diseases
2004
Evidence for mitochondrial dysfunction in Parkinson's disease—a critical appraisal
1994
Dopamine Oxidation Alters Mitochondrial Respiration and Induces Permeability Transition in Brain Mitochondria
1999
Oxidative stress as a cause of Parkinson's disease
1991
Endogenous Parkin Preserves Dopaminergic Substantia Nigral Neurons following Mitochondrial DNA Mutagenic Stress
2015
Oxidative damage to mitochondrial DNA shows marked age‐dependent increases in human brain
1993
Role of mitochondria in the etiology and pathogenesis of Parkinson's disease
1995
The Role of Iron in Neurodegeneration
1999
Metabolism and functions of glutathione in brain
2000 Standout
Role of controlled cardiac reoxygenation in reducing nitric oxide production and cardiac oxidant damage in cyanotic infantile hearts.
1994 StandoutNobel
Oxidative metabolites of 5-S-cysteinyldopamine inhibit the α-ketoglutarate dehydrogenase complex: possible relevance to the pathogenesis of Parkinson's disease
2000
Complex I deficiency in Parkinson's disease frontal cortex
2007
The oxidant stress hypothesis in Parkinson's disease: Evidence supporting it
1992
Parkinson's Disease
1998 Standout
[42]Assessment of mitochondrial oxidative phosphorylation in patient muscle biopsies, lymphoblasts, and transmitochondrial cell lines
1996
Age- and peroxidative stress-related modifications of the cerebral enzymatic activities linked to mitochondria and the glutathione system
1995
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
Early α-synuclein lipoxidation in neocortex in Lewy body diseases
2006
Lack of up‐regulation of ferritin is associated with sustained iron regulatory protein‐1 binding activity in the substantia nigra of patients with Parkinson's disease
2002
Role of Mitochondria in Parkinson Disease
1999
Mitochondria and ageing
2000
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
The role of iron in brain ageing and neurodegenerative disorders
2014 Standout
Is defective electron transport at the hub of aging?
2003
Alterations in the distribution of glutathione in the substantia nigra in Parkinson's disease
1997
Altered Proteasomal Function in Sporadic Parkinson's Disease
2002
Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia
1994
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Low platelet mitochondrial complex I and complex II/III activity in early untreated parkinson's disease
1995
Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α
2006 Standout
Glial Cells Mediate Toxicity in Glutathione‐Depleted Mesencephalic Cultures
1999
Interrelationships between astrocyte function, oxidative stress and antioxidant status within the central nervous system
1997
Excitatory Amino Acids as a Final Common Pathway for Neurologic Disorders
1994 Standout
Inflammatory Regulators in Parkinson's Disease: iNOS, Lipocortin-1, and Cyclooxygenases-1 and -2
2000
Nuclear and mitochondrial genetics in Parkinson's disease.
1995
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
2000 Standout
Advances in Our Understanding of the Mechanisms of the Neurotoxicity of MPTP and Related Compounds
1993
Parkin enhances mitochondrial biogenesis in proliferating cells
2006
Oxidative stress and neurodegenerative disorders
1998
1991
Selective Neuronal Degeneration in Huntington's Disease
2006
Glutathione‐related enzymes in brain in Parkinson's disease
1994
Cytochrome c oxidase deficient cells accumulate in the hippocampus and choroid plexus with age
2001
Oxidative Stress in Huntington's Disease
1999
Increased Caspase 3 and Bax Immunoreactivity Accompany Nuclear GAPDH Translocation and Neuronal Apoptosis in Parkinson's Disease
2000
Glutathione depletion in rat brain does not cause nigrostriatal pathway degeneration
1997
Neuromelanin associated redox‐active iron is increased in the substantia nigra of patients with Parkinson's disease
2003
Parkinson's disease: pathophysiology
1991
A Fluorogenic Aryl Fluorosulfate for Intraorganellar Transthyretin Imaging in Living Cells and in Caenorhabditis elegans
2015 StandoutNobel
Brain trace elements and aging
1999
Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling
2011 Standout
Involvement of Mitochondrial Complex II Defects in Neuronal Death Produced by N-Terminus Fragment of Mutated Huntingtin
2006
Iron induced oxidative stress and mitochondrial dysfunction: relevance to Parkinson's disease
1993
Mitochondrial involvement in the ageing process. Facts and controversies
1997
Oxidative stress, mitochondrial DNA mutation, and apoptosis in aging.
2007
Mice Deficient in Cellular Glutathione Peroxidase Show Increased Vulnerability to Malonate, 3-Nitropropionic Acid, and 1-Methyl-4-Phenyl-1,2,5,6-Tetrahydropyridine
2000 Standout
1995
[3H]Dihydrorotenone Binding to NADH: Ubiquinone Reductase (Complex I) of the Electron Transport Chain: An Autoradiographic Study
1996
Use of Transmitochondrial Cybrids To Assign a Complex I Defect to the Mitochondrial DNA-Encoded NADH Dehydrogenase Subunit 6 Gene Mutation at Nucleotide Pair 14459 That Causes Leber Hereditary Optic Neuropathy and Dystonia
1996
Spermidine in health and disease
2018 StandoutScience
Small molecule probes to quantify the functional fraction of a specific protein in a cell with minimal folding equilibrium shifts
2014 StandoutNobel
Mitochondrial Diseases in Man and Mouse
1999 StandoutScience
ETIOLOGY AND PATHOGENESIS OF PARKINSON'S DISEASE
1999
Oxidative Damage in Neurodegenerative Diseases
1997
Adapting Proteostasis for Disease Intervention
2008 StandoutScience
Mitochondrial Contribution to Parkinson's Disease Pathogenesis
2011
Mitochondrial Dysfunction and Type 2 Diabetes
2005 StandoutScience
Failure of the ubiquitin–proteasome system in Parkinson's disease
2001
Iron Toxicity in Diseases of Aging: Alzheimer's Disease, Parkinson's Disease and Atherosclerosis
2009
The development of mitochondrial medicine.
1994
Impaired Degradation of Mutant α-Synuclein by Chaperone-Mediated Autophagy
2004 StandoutScience
Bradykinin B1 and B2 receptors both have protective roles in renal ischemia/reperfusion injury
2007 StandoutNobel
Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet
2011 StandoutNobel
Mitochondrial Dysfunction and Oxidative Damage in parkin-deficient Mice
2004
Oxidative Stress, Glutamate, and Neurodegenerative Disorders
1993 StandoutScience
Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control
2014
Altered mitochondrial function, iron metabolism and glutathione levels in Parkinson's disease
1993
Mutations in the DJ-1 Gene Associated with Autosomal Recessive Early-Onset Parkinsonism
2003 StandoutScience
Altered Glial Function Causes Neuronal Death and Increases Neuronal Susceptibility to 1‐Methyl‐4‐Phenylpyridinium‐ and 6‐Hydroxydopamine‐Induced Toxicity in Astrocytic/Ventral Mesencephalic Co‐Cultures
1999
Accelerated expansion of pathogenic mitochondrial DNA heteroplasmies in Huntington’s disease
2021
Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism
1999
Oxidative stress in neurodegeneration: cause or consequence?
2004 Standout
Mitochondrial involvement in the ageing process. Facts and controversies
1997
Works of V. M. Mann being referenced
A 31P magnetic resonance spectroscopy study of mitochondrial function in skeletal muscle of patients with Parkinson's disease
1994
Analyses of mitochondrial respiratory chain function and mitochondrial DNA deletion in human skeletal muscle: Effect of ageing
1992
Indices of oxidative stress and mitochondrial function in individuals with incidental Lewy body disease
1994
Complex I, Iron, and ferritin in Parkinson's disease substantia nigra
1994
BRAIN, SKELETAL MUSCLE AND PLATELET HOMOGENATE MITOCHONDRIAL FUNCTION IN PARKINSON'S DISEASE
1992
Human mitochondrial complex I dysfunction
1992
Mitochondrial defect in Huntington's disease caudate nucleus
1996
Anatomic and Disease Specificity of NADH CoQ1 Reductase (Complex I) Deficiency in Parkinson's Disease
1990