Citation Impact
Citing Papers
Cells Silenced for SDHB Expression Display Characteristic Features of the Tumor Phenotype
2008
Cell-Permeating α -Ketoglutarate Derivatives Alleviate Pseudohypoxia in Succinate Dehydrogenase-Deficient Cells
2007
Patterns of Gene Expression and Copy-Number Alterations in von-Hippel Lindau Disease-Associated and Sporadic Clear Cell Carcinoma of the Kidney
2009 StandoutNobel
Neuronal apoptosis linked to EglN3 prolyl hydroxylase and familial pheochromocytoma genes: Developmental culling and cancer
2005 StandoutNobel
HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability
2005 StandoutNobel
Loss of succinate dehydrogenase activity results in dependency on pyruvate carboxylation for cellular anabolism
2015
Treatment of kidney cancer
2009 StandoutNobel
Hypoxia-Inducible Factor-1-Dependent Repression of E-cadherin in von Hippel-Lindau Tumor Suppressor–Null Renal Cell Carcinoma Mediated by TCF3, ZFHX1A, and ZFHX1B
2006 StandoutNobel
Hypoxia-Inducible Factor Linked to Differential Kidney Cancer Risk Seen with Type 2A and Type 2B VHL Mutations
2007 StandoutNobel
Specific disintegration of complex II succinate:ubiquinone oxidoreductase links pH changes to oxidative stress for apoptosis induction
2010
Allosteric phenomena in cytochrome P450‐catalyzed monooxygenations
2001
Acromegaly
2006 Standout
Hereditary Paraganglioma/Pheochromocytoma and Inherited Succinate Dehydrogenase Deficiency
2005
A role for mitochondrial enzymes in inherited neoplasia and beyond
2003
pVHL Acts as an Adaptor to Promote the Inhibitory Phosphorylation of the NF-κB Agonist Card9 by CK2
2007 StandoutNobel
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
2‐Methoxyestradiol, a Promising Anticancer Agent
2003
Targeted Inactivation of Fh1 Causes Proliferative Renal Cyst Development and Activation of the Hypoxia Pathway
2007
National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants
2011 Standout
Human liver carbamazepine metabolism
1994
Phaeochromocytoma
2005 Standout
HIF2α cooperates with RAS to promote lung tumorigenesis in mice
2009 StandoutNobel
VHL and p53: Tumor Suppressors Team Up to Prevent Cancer
2006 StandoutNobel
A Multicenter, Randomized Trial of Treatment for Mild Gestational Diabetes
2009 Standout
Otto Warburg's contributions to current concepts of cancer metabolism
2011 Standout
SDH5 Mutations and Familial Paraganglioma: Somewhere Warburg is Smiling
2009 StandoutNobel
Succinate dehydrogenase and fumarate hydratase: linking mitochondrial dysfunction and cancer
2006
Novel succinate dehydrogenase subunit B (SDHB) mutations in familial phaeochromocytomas and paragangliomas, but an absence of somatic SDHB mutations in sporadic phaeochromocytomas
2003
What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
2013 StandoutNobel
Cancer genes and the pathways they control
2004 Standout
Mitochondria, Oxidants, and Aging
2005 Standout
Differential association of oral and transdermal oestrogen-replacement therapy with venous thromboembolism risk
2003
Pre-eclampsia
2005 Standout
Regulation of cancer cell metabolism
2011 Standout
Failure to prolyl hydroxylate hypoxia‐inducible factor α phenocopies VHL inactivation in vivo
2006 StandoutNobel
SDH mutations in cancer
2011
Developing and evaluating complex interventions: the new Medical Research Council guidance
2008 Standout
Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
2001 Standout
Human AlkB Homologue 5 Is a Nuclear 2-Oxoglutarate Dependent Oxygenase and a Direct Target of Hypoxia-Inducible Factor 1α (HIF-1α)
2011 StandoutNobel
Heterogeneous Effects of Direct Hypoxia Pathway Activation in Kidney Cancer
2015 StandoutNobel
Impact of self monitoring of blood glucose in the management of patients with non-insulin treated diabetes: open parallel group randomised trial
2007
Clinician’s Guide to Cardiopulmonary Exercise Testing in Adults
2010 Standout
The Emerging Hallmarks of Cancer Metabolism
2016 Standout
Microtubules as a target for anticancer drugs
2004 Standout
The von Hippel–Lindau protein, HIF hydroxylation, and oxygen sensing
2005 StandoutNobel
Human Cytochrome P450 Enzymes: A Status Report Summarizing Their Reactions, Substrates, Inducers, and Inhibitors
1997
Signalling hypoxia by HIF hydroxylases
2005 StandoutNobel
Sex differences in immune responses
2016 Standout
The effects of 2,3,7,8-Tetrachlorodibenzo-p-dioxin on estrogen metabolism in MCF-7 breast cancer cells: Evidence for induction of a novel 17β-estradiol 4-hydroxylase
1994
The TCA cycle and tumorigenesis: the examples of fumarate hydratase and succinate dehydrogenase
2003
16Alpha-hydroxylation of estrone by human cytochrome P4503A4/5
1998
Redox stress is not essential for the pseudo-hypoxic phenotype of succinate dehydrogenase deficient cells
2006
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
2008 StandoutNobel
PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2
2016 StandoutNobel
Developmental Pharmacology — Drug Disposition, Action, and Therapy in Infants and Children
2003 Standout
The Complex Role of Estrogens in Inflammation
2007 Standout
Dual Role of Human Cytochrome P450 3A4 Residue Phe-304 in Substrate Specificity and Cooperativity
2000
The Von Hippel-Lindau Tumor Suppressor Gene and Kidney Cancer
2004 StandoutNobel
Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications
2019 Standout
Functional Diagnostics in Mitochondrial Diseases
2007
Systemic Complications of Acromegaly: Epidemiology, Pathogenesis, and Management
2004 Standout
First Trimester Insulin Resistance and Subsequent Preeclampsia: A Prospective Study
2002
First Trimester Insulin Resistance and Subsequent Preeclampsia: A Prospective Study
2002
Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release
2014 Standout
Mechanisms of Estrogen Action
2001 Standout
Mutations in the SDHB gene are associated with extra-adrenal and/or malignant phaeochromocytomas.
2003
pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner
2016 StandoutScienceNobel
Metabolic reprogramming and cancer progression
2020 StandoutScience
The Epidemiology of Venous Thromboembolism
2003 Standout
Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus
2011
The von Hippel-Lindau Tumor Suppressor Protein and Clear Cell Renal Carcinoma
2007 StandoutNobel
Transsphenoidal Microsurgery for Growth Hormone-Secreting Pituitary Adenomas: Initial Outcome and Long-Term Results
1998
Role ofVHLGene Mutation in Human Cancer
2004 StandoutNobel
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
Structure and Chemistry of Cytochrome P450
2005 Standout
Works of V. Kerlan being referenced
Functional Consequences of aSDHBGene Mutation in an Apparently Sporadic Pheochromocytoma
2002
Self-monitoring of blood glucose significantly improves metabolic control in patients with type 2 diabetes mellitus: the Auto-Surveillance Intervention Active (ASIA) study
2003
Nature of cytochromes P450 involved in the 2-/4-hydroxylations of estradiol in human liver microsomes
1992
Longitudinal study of maternal plasma bioavailable testosterone and androstanediol glucuronide levels during pregnancy
1994
Ocular naevus and melanoma in acromegaly
1997
Differential effects of oral and transdermal postmenopausal estrogen replacement therapies on C-reactive protein.
2003
Differential Effects of Oral and Transdermal Estrogen/Progesterone Regimens on Sensitivity to Activated Protein C Among Postmenopausal Women
2003
Differential effects of oral and transdermal postmenopausal estrogen replacement therapies on C-reactive protein
2003