Citation Impact
Citing Papers
Formylglycine-generating enzyme binds substrate directly at a mononuclear Cu(I) center to initiate O 2 activation
2019 StandoutNobel
Directed evolution of cytochrome c for carbon–silicon bond formation: Bringing silicon to life
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Mechanistic Investigations of Anaerobic Sulfatase-Maturating Enzyme: Direct C β H-Atom Abstraction Catalyzed by a Radical AdoMet Enzyme
2009
A New Type of Bacterial Sulfatase Reveals a Novel Maturation Pathway in Prokaryotes
2006
Sequence determinants directing conversion of cysteine to formylglycine in eukaryotic sulfatases
1999
Function and Structure of a Prokaryotic Formylglycine-generating Enzyme
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Paralog of the formylglycine‐generating enzyme – retention in the endoplasmic reticulum by canonical and noncanonical signals
2008
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
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Screening for lysosomal disorders
1994
A novel protein modification generating an aldehyde group in sulfatases: its role in catalysis and disease
1998
The Protein Data Bank
2000 Standout
Sulfatases: Structure, Mechanism, Biological Activity, Inhibition, and Synthetic Utility
2004
Friedel–Crafts‐Type Mechanism for the Enzymatic Elimination of Ammonia from Histidine and Phenylalanine
2005
Catalytic Mechanism of the Arylsulfatase Promiscuous Enzyme from Pseudomonas Aeruginosa
2012
Early Formation of mRNP
2003 StandoutNobel
Computational Enzyme Design
2013 StandoutNobel
A Block to mRNA Nuclear Export in S. cerevisiae Leads to Hyperadenylation of Transcripts that Accumulate at the Site of Transcription
2001 StandoutNobel
Conserved core structure and active site residues in alkaline phosphatase superfamily enzymes
2001
STRING v10: protein–protein interaction networks, integrated over the tree of life
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The Iron Sulfur Protein AtsB Is Required for Posttranslational Formation of Formylglycine in the Klebsiella Sulfatase
1999
Engineering of an enantioselective tyrosine aminomutase by mutation of a single active site residue in phenylalanine aminomutase
2010 StandoutNobel
Mechanisms Controlling Mitochondrial Biogenesis and Respiration through the Thermogenic Coactivator PGC-1
1999 Standout
Crystal structure of a covalent intermediate of endogenous human arylsulfatase A
2003
Molecular Characterization of the Human Cα-formylglycine-generating Enzyme
2005
Crystal structure of human catecholamine sulfotransferase 1 1Edited by R. Huber
1999
Molecular Basis for Multiple Sulfatase Deficiency and Mechanism for Formylglycine Generation of the Human Formylglycine-Generating Enzyme
2005
The Human Transcription Factors
2018 Standout
The human SUMF1 gene, required for posttranslational sulfatase modification, defines a new gene family which is conserved from pro- to eukaryotes
2003
Expression, Localization, Structural, and Functional Characterization of pFGE, the Paralog of the Cα-Formylglycine-generating Enzyme
2005
The Multiple Sulfatase Deficiency Gene Encodes an Essential and Limiting Factor for the Activity of Sulfatases
2003
Structure and organization of the human galactocerebrosidase (GALC) gene
1995
Expanding the Enzyme Universe: Accessing Non‐Natural Reactions by Mechanism‐Guided Directed Evolution
2015 StandoutNobel
Posttranslational Formation of Formylglycine in Prokaryotic Sulfatases by Modification of Either Cysteine or Serine
1998
Sulfotransferases and Sulfatases in Mycobacteria
2002 StandoutNobel
Dephosphorylation of the Mannose‐6 Phosphate Recognition Marker is Localized in Late Compartments of the Endocytic Route
1996
Potent active site-directed inhibition of steroid sulphatase by tricyclic coumarin-based sulphamates
2000
Structural and Catalytic Similarities between Nucleotide Pyrophosphatases/Phosphodiesterases and Alkaline Phosphatases
2001
Direct Evidence for ArOS Bond Cleavage upon Inactivation of Pseudomonas aeruginosa Arylsulfatase by Aryl Sulfamates
2008
Structure of Human Estrone Sulfatase Suggests Functional Roles of Membrane Association
2003
Sulfatases, Trapping of the Sulfated Enzyme Intermediate by Substituting the Active Site Formylglycine
1998
Lysosomal storage disorders
2005
Sulfotransferases: Structure, Mechanism, Biological Activity, Inhibition, and Synthetic Utility
2004
Riding the sulfur cycle – metabolism of sulfonates and sulfate esters in Gram-negative bacteria
2000
Molecular genetics of metachromatic leukodystrophy
1994
Sulfotransferases, sulfatases and formylglycine-generating enzymes: a sulfation fascination
2008
ERp44 Mediates a Thiol-independent Retention of Formylglycine-generating Enzyme in the Endoplasmic Reticulum
2008
Molecular basis of multiple sulfatase deficiency, mucolipidosis II/III and Niemann–Pick C1 disease — Lysosomal storage disorders caused by defects of non-lysosomal proteins
2008
Multiple Sulfatase Deficiency Is Caused by Mutations in the Gene Encoding the Human Cα-Formylglycine Generating Enzyme
2003
A New Member of the Alkaline Phosphatase Superfamily with a Formylglycine Nucleophile: Structural and Kinetic Characterisation of a Phosphonate Monoester Hydrolase/Phosphodiesterase from Rhizobium leguminosarum
2008
Mechanism‐Inspired Engineering of Phenylalanine Aminomutase for Enhanced β‐Regioselective Asymmetric Amination of Cinnamates
2011 StandoutNobel
A Simple Enantioconvergent and Chemoenzymatic Synthesis of Optically Active α‐Substituted Amides
2011 StandoutNobel
Mycobacterium tuberculosis Rv3406 Is a Type II Alkyl Sulfatase Capable of Sulfate Scavenging
2013 StandoutNobel
Structure of sulfamidase provides insight into the molecular pathology of mucopolysaccharidosis IIIA
2014
Kinetic measurements and mechanism determination of Stf0 sulfotransferase using mass spectrometry
2005 StandoutNobel
Characterization of Posttranslational Formylglycine Formation by Luminal Components of the Endoplasmic Reticulum
2001
A superfamily of metalloenzymes unifies phosphopentomutase and cofactor‐independent phosphoglycerate mutase with alkaline phosphatases and sulfatases
1998
Crystal Structure of an Enzyme-Substrate Complex Provides Insight into the Interaction between Human Arylsulfatase A and its Substrates During Catalysis
2001
Catalytic promiscuity and the evolution of new enzymatic activities
1999
A novel amino acid modification in sulfatases that is defective in multiple sulfatase deficiency
1995
Aryl sulfamates are broad spectrum inactivators of sulfatases: Effects on sulfatases from various sources
2008
Asymmetric Multicomponent Reactions (AMCRs): The New Frontier
2005 Standout
Human sulfatases: A structural perspective to catalysis
2007
Molecular Architecture of the Human Pre-mRNA 3′ Processing Complex
2009 StandoutNobel
Sulfatases and sulfatase modifying factors: an exclusive and promiscuous relationship
2005
Synthesis of Heterobifunctional Protein Fusions Using Copper‐Free Click Chemistry and the Aldehyde Tag
2012 StandoutNobel
Molecular Basis for G Protein Control of the Prokaryotic ATP Sulfurylase
2006 StandoutNobel
Novel cofactors via post-translational modifications of enzyme active sites
2000
1.3 Å Structure of Arylsulfatase from Pseudomonas aeruginosa Establishes the Catalytic Mechanism of Sulfate Ester Cleavage in the Sulfatase Family
2001
Lysosomal storage diseases
1995
A Fluorogenic Aryl Fluorosulfate for Intraorganellar Transthyretin Imaging in Living Cells and in Caenorhabditis elegans
2015 StandoutNobel
In Vitro Characterization of AtsB, a Radical SAM Formylglycine-Generating Enzyme That Contains Three [4Fe-4S] Clusters
2008
Sulfatase-activated fluorophores for rapid discrimination of mycobacterial species and strains
2013 StandoutNobel
Mouse model for the lysosomal disorder galactosialidosis and correction of the phenotype with overexpressing erythroid precursor cells.
1995 StandoutNobel
Quantitative exploration of the molecular origin of the activation of GTPase
2013 StandoutNobel
Catalytic Proficiency: The Extreme Case of S–O Cleaving Sulfatases
2011
Sulfatase Activity of E. coli Alkaline Phosphatase Demonstrates a Functional Link to Arylsulfatases, an Evolutionarily Related Enzyme Family
1998
Residues Critical for Formylglycine Formation and/or Catalytic Activity of Arylsulfatase A
1998
Directed Evolution: Bringing New Chemistry to Life
2017 StandoutNobel
New Aldehyde Tag Sequences Identified by Screening Formylglycine Generating Enzymes in Vitro and in Vivo
2008 StandoutNobel
Rv2131c fromMycobacterium tuberculosisIs a CysQ 3′-Phosphoadenosine-5′-phosphatase
2008 StandoutNobel
Enzymatische Eliminierung von Ammoniak aus Histidin und Phenylalanin: der Friedel‐Crafts‐ähnliche Mechanismus
2005
In the light of directed evolution: Pathways of adaptive protein evolution
2009 StandoutNobel
Experimental and Theoretical Insights into the Mechanisms of Sulfate and Sulfamate Ester Hydrolysis and the End Products of Type I Sulfatase Inactivation by Aryl Sulfamates
2014
Efficient Catalytic Promiscuity in an Enzyme Superfamily: An Arylsulfatase Shows a Rate Acceleration of 1013 for Phosphate Monoester Hydrolysis
2008
Further Characterization of Cys-Type and Ser-Type Anaerobic Sulfatase Maturating Enzymes Suggests a Commonality in the Mechanism of Catalysis
2013
Occurrence, Classification, and Biological Function of Hydrogenases: An Overview
2007 Standout
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Characterization and Mutagenesis of Gal/GlcNAc-6-O-sulfotransferases
2002 StandoutNobel
Formation of mRNA 3′ Ends in Eukaryotes: Mechanism, Regulation, and Interrelationships with Other Steps in mRNA Synthesis
1999
Carbohydrate Sulfotransferases of the GalNAc/Gal/GlcNAc6ST Family
2002 StandoutNobel
Conversion of cysteine to formylglycine: A protein modification in the endoplasmic reticulum
1997
Enantiocomplementary inverting sec-alkylsulfatase activity in cyano- and thio-bacteria Synechococcus and Paracoccus spp.: selectivity enhancement by medium engineering
2009
A sulfated metabolite produced bystf3negatively regulates the virulence ofMycobacteriumtuberculosis
2006 StandoutNobel
The Caenorhabditis elegans mucolipin-like gene cup-5 is essential for viability and regulates lysosomes in multiple cell types
2002 StandoutNobel
Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag
2009 StandoutNobel
SULFATASES AND HUMAN DISEASE
2005
Overlapping functions of lysosomal acid phosphatase (LAP) and tartrate-resistant acid phosphatase (Acp5) revealed by doubly deficient mice
2001 StandoutNobel
MmpL8 is required for sulfolipid-1 biosynthesis and Mycobacterium tuberculosis virulence
2003 StandoutNobel
Addressing Open Questions about Phosphate Hydrolysis Pathways by Careful Free Energy Mapping
2012 StandoutNobel
The ENZYME data bank.
1993
Biology of Oligodendrocyte and Myelin in the Mammalian Central Nervous System
2001 Standout
Enzymatic Mechanisms of Phosphate and Sulfate Transfer
2006
Sphingolipide – ihre Stoffwechselwege und die Pathobiochemie neurodegenerativer Erkrankungen
1999
Progress in Ab Initio QM/MM Free-Energy Simulations of Electrostatic Energies in Proteins: Accelerated QM/MM Studies of pKa, Redox Reactions and Solvation Free Energies
2008 StandoutNobel
Formylglycine, a Post-Translationally Generated Residue with Unique Catalytic Capabilities and Biotechnology Applications
2014 StandoutNobel
Multiple sulfatase deficiency: catalytically inactive sulfatases are expressed from retrovirally introduced sulfatase cDNAs.
1992
Escherichia coli K1 aslA Contributes to Invasion of Brain Microvascular Endothelial Cells In Vitro and In Vivo
2000
Quantifying the Mechanism of Phosphate Monoester Hydrolysis in Aqueous Solution by Evaluating the Relevant Ab Initio QM/MM Free-Energy Surfaces
2013 StandoutNobel
Protein Glycoengineering Enabled by the Versatile Synthesis of Aminooxy Glycans and the Genetically Encoded Aldehyde Tag
2011 StandoutNobel
Isoenzyme-specific regulation of genes involved in energy metabolism by hypoxia: similarities with the regulation of erythropoietin
1996 StandoutNobel
NRF-1, an activator involved in nuclear-mitochondrial interactions, utilizes a new DNA-binding domain conserved in a family of developmental regulators.
1993
On the Interpretation of the Observed Linear Free Energy Relationship in Phosphate Hydrolysis: A Thorough Computational Study of Phosphate Diester Hydrolysis in Solution
2008 StandoutNobel
Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition
2005
Discovery of sulfated metabolites in mycobacteria with a genetic and mass spectrometric approach
2002 StandoutNobel
Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1.
1994 Standout
Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms?
2012 Standout
Works of V. Gieselmann being referenced
Structure of the arylsulfatase A gene
1990
Molecular Genetics of Metachromatic Leukodystrophy
1991
Low arylsulphatase A activity and choreoathetotic syndrome in three siblings: differentiation of pseudodeficiency from metachromatic leukodystrophy
1991
Glycosylation and phosphorylation of arylsulfatase A.
1994
Mutations in the arylsulfatase A pseudodeficiency allele causing metachromatic leukodystrophy.
1991
Arylsulfatase A pseudodeficiency: loss of a polyadenylylation signal and N-glycosylation site.
1989
Restoration of arylsulphatase A activity in human-metachromatic-leucodystrophy fibroblasts via retroviral-vector-mediated gene transfer
1991
Crystal Structure of Human Arylsulfatase A: The Aldehyde Function and the Metal Ion at the Active Site Suggest a Novel Mechanism for Sulfate Ester Hydrolysis,
1998