Citation Impact
Citing Papers
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
Computational Thermostabilization of an Enzyme
2005 StandoutScienceNobel
Synergistic Suppression of Microtubule Dynamics by Discodermolide and Paclitaxel in Non-Small Cell Lung Carcinoma Cells
2004
Phase III Study Comparing Cisplatin Plus Gemcitabine With Cisplatin Plus Pemetrexed in Chemotherapy-Naive Patients With Advanced-Stage Non–Small-Cell Lung Cancer
2008 Standout
Alteration of enzyme specificity by computational loop remodeling and design
2009 StandoutNobel
EglN2 associates with the NRF 1‐ PGC 1α complex and controls mitochondrial function in breast cancer
2015 StandoutNobel
Rationally Designed Integrin β3 Mutants Stabilized in the High Affinity Conformation
2008 StandoutNobel
Catalytic Asymmetric Three‐Component Synthesis of Homoallylic Amines
2013 StandoutNobel
Cell mechanics and the cytoskeleton
2010 StandoutNature
Suppression of tumor growth through disruption of hypoxia-inducible transcription
2000 StandoutNobel
Targeting hypoxia in cancer therapy
2011 Standout
Molecular imaging in living subjects: seeing fundamental biological processes in a new light
2003 Standout
Iron/ethylcellulose (core/shell) nanoplatform loaded with 5-fluorouracil for cancer targeting
2010
Increased cytotoxicity and bystander effect of 5-fluorouracil and 5′-deoxy-5-fluorouridine in human colorectal cancer cells transfected with thymidine phosphorylase
1999
The structure of Escherichia coli cytosine deaminase 1 1Edited by I. A. Wilson
2002
Drug penetration in solid tumours
2006 Standout
Multiple folate enzyme inhibition: mechanism of a novel pyrrolopyrimidine-based antifolate LY231514 (MTA)
1998
Two‐Photon Absorption and the Design of Two‐Photon Dyes
2009 Standout
Enzyme and Pathway Engineering for Suicide Gene Therapy
2006
The tumour microenvironment after radiotherapy: mechanisms of resistance and recurrence
2015 Standout
Synergistic Anticancer Effects of Ganciclovir/Thymidine Kinase and 5-Fluorocytosine/Cytosine Deaminase Gene Therapies
1998
Biochemical effects of folate-based inhibitors of thymidylate synthase in MGH-U1 cells
1994
Ligand-induced distortion of an active site in thymidylate synthase upon binding anticancerdrug 1843U89
1995
Exploiting tumour hypoxia in cancer treatment
2004 Standout
Targeting multidrug resistance in cancer
2006 Standout
The 1.14 Å Crystal Structure of Yeast Cytosine Deaminase
2003
Catalytic Functionalization of Indoles in a New Dimension
2009 Standout
Gene directed enzyme/prodrug therapy of cancer: Historical appraisal and future prospectives
2001
Exploiting the hypoxic cancer cell: mechanisms and therapeutic strategies
2000
Herpes Simplex Virus Thymidine Kinase Gene Transfer for Controlled Graft-versus-Host Disease and Graft-versus-Leukemia: Clinical Follow-up and Improved New Vectors
1998
Regulation and Function of the PD-L1 Checkpoint
2018 Standout
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
A review of the pharmacology and clinical activity of new chemotherapy agents for the treatment of colorectal cancer
1999
Matching chelators to radiometals for radiopharmaceuticals
2013 Standout
In Vivo Replication-Deficient Adenovirus Vector-Mediated Transduction of the Cytosine Deaminase Gene Sensitizes Glioma Cells to 5-Fluorocytosine
1996
Prodrug activation enzymes in cancer gene therapy
2000
Chemotherapy Dosing Part I: Scientific Basis for Current Practice and Use of Body Surface Area
2006
Interactions with Aromatic Rings in Chemical and Biological Recognition
2003 Standout
Microtubules as a target for anticancer drugs
2004 Standout
Negative Regulation of Hypoxic Responses via Induced Reptin Methylation
2010 StandoutNobel
Samarium-153 and Lutetium-177 Chelation Properties of Selected Macrocyclic and Acyclic Ligands
1998
Hypoxic Tumors and Their Effect on Immune Cells and Cancer Therapy
2010
5-Fluorouracil: mechanisms of action and clinical strategies
2003 Standout
Tumor-selective transgene expression in vivo mediated by an E2F-responsive adenoviral vector
1997 StandoutNobel
New drugs in the treatment of colorectal carcinoma
1998
Theoretical Basis, Experimental Design, and Computerized Simulation of Synergism and Antagonism in Drug Combination Studies
2006 Standout
Orally Absorbed Cyclic Peptides
2017
3d Transition Metals for C–H Activation
2018 Standout
Coordinating Radiometals of Copper, Gallium, Indium, Yttrium, and Zirconium for PET and SPECT Imaging of Disease
2010 Standout
Antifolate resistance mediated by the multidrug resistance proteins MRP1 and MRP2.
1999
Signaling Recognition Events with Fluorescent Sensors and Switches
1997 Standout
Conditional Glycosylation in Eukaryotic Cells Using a Biocompatible Chemical Inducer of Dimerization
2008 StandoutNobel
Bis- and Trisindolylmethanes (BIMs and TIMs)
2009 Standout
Hydroamination: Direct Addition of Amines to Alkenes and Alkynes
2008 Standout
Phase III Study of Pemetrexed in Combination With Cisplatin Versus Cisplatin Alone in Patients With Malignant Pleural Mesothelioma
2003 Standout
Novel Fluorometric Sensing of Ammonium Ions by Pyrene Functionalized Homotrioxacalix[3]arenes
1994
Synthesis and Functionalization of Indoles Through Palladium-catalyzed Reactions
2005 Standout
Pyrene-Based Materials for Organic Electronics
2011
Recent developments in indole ring synthesis—methodology and applications
2000 Standout
The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry
2007 Standout
Highly Selective Wet Etch for High-Resolution Three-Dimensional Nanostructures in Arsenic Sulfide All-Inorganic Photoresist
2007
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
A Bifunctional Molecule That Displays Context-Dependent Cellular Activity
2003
Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds
2011 Standout
Folate-Synthesizing Enzyme System as Target for Development of Inhibitors and Inhibitor Combinations against Candida albicansSynthesis and Biological Activity of New 2,4-Diaminopyrimidines and 4‘-Substituted 4-Aminodiphenyl Sulfones
2003
Functional π-Gelators and Their Applications
2014 Standout
Transition-Metal-Catalyzed C−S, C−Se, and C−Te Bond Formation via Cross-Coupling and Atom-Economic Addition Reactions
2011 Standout
LY231514, a pyrrolo[2,3-d]pyrimidine-based antifolate that inhibits multiple folate-requiring enzymes.
1997
Direct evidence for the participation of gap junction-mediated intercellular communication in the transmission of damage signals from alpha -particle irradiated to nonirradiated cells
2001 Standout
Noninvasive quantitation of cytosine deaminase transgene expression in human tumor xenografts with in vivo magnetic resonance spectroscopy
1999
Preparation of Benzo[c]carbazol-6-amines via Manganese-Catalyzed Enaminylation of 1-(Pyrimidin-2-yl)-1H-indoles with Ketenimines and Subsequent Oxidative Cyclization
2018
Open Analogues of Arcyriaflavin A. Synthesis through Diels−Alder Reaction between Maleimides and 1-Aryl-3-tert-butyldimethylsiloxy-1,3-butadienes
2000
Structural Investigations into the Stereochemistry and Activity of a Phenylalanine-2,3-aminomutase from Taxus chinensis
2014 StandoutNobel
THE DEVELOPMENT AND CLINICAL UTILITY OF THE TAXANE CLASS OF ANTIMICROTUBULE CHEMOTHERAPY AGENTS
1997
Magnetic Nanoparticles: Design and Characterization, Toxicity and Biocompatibility, Pharmaceutical and Biomedical Applications
2012 Standout
Transition-Metal-Catalyzed Addition of Heteroatom−Hydrogen Bonds to Alkynes
2004 Standout
Trends in the Aggressiveness of Cancer Care Near the End of Life
2004 Standout
HIF-1 and human disease: one highly involved factor
2000 StandoutNobel
The Catalytic Asymmetric Fischer Indolization
2011 StandoutNobel
Heterocyclic Nanographenes and Other Polycyclic Heteroaromatic Compounds: Synthetic Routes, Properties, and Applications
2016 Standout
Superiority of yeast over bacterial cytosine deaminase for enzyme/prodrug gene therapy in colon cancer xenografts.
1999
Isolation and Synthesis of Biologically Active Carbazole Alkaloids
2002 Standout
Thermally Activated Delayed Fluorescence Materials Towards the Breakthrough of Organoelectronics
2014 Standout
Dose translation from animal to human studies revisited
2007 Standout
Works of V C Knick being referenced
Vinorelbine Tartrate and Paclitaxel Combinations: Enhanced Activity Against In Vivo P388 Murine Leukemia Cells
1995
[(1-Pyrenylmethyl)amino] alcohols, a new class of antitumor DNA intercalators. Discovery and initial amine side chain structure-activity studies
1990
Pharmacokinetics and tissue distribution of the nonadecapeptide Moli1901 in rats and mice
2003
In vivo antitumor activity of 5-fluorocytosine on human colorectal carcinoma cells genetically modified to express cytosine deaminase.
1993
Synthesis and biological properties of 1069C: a new synthetic antitumour agent with very low cross-resistance potential
1992
High-Affinity Inhibitors of Dihydrofolate Reductase: Antimicrobial and Anticancer Activities of 7,8-Dialkyl-1,3-diaminopyrrolo[3,2-f]quinazolines with Small Molecular Size
1996
Biochemical and cellular pharmacology of 1843U89, a novel benzoquinazoline inhibitor of thymidylate synthase.
1993
Enzyme/prodrug gene therapy: comparison of cytosine deaminase/5-fluorocytosine versus thymidine kinase/ganciclovir enzyme/prodrug systems in a human colorectal carcinoma cell line.
1995
Improved biodistribution, tumor targeting, and reduced immunogenicity in mice with a gamma 4 variant of Campath-1H.
1995
Evaluation of arylmethylaminopropanediols by a novel in vitro pharmacodynamic assay: correlation with antitumor activity in vivo.
1990
5-Ethynyluracil (776C85): a potent modulator of the pharmacokinetics and antitumor efficacy of 5-fluorouracil.
1993