Citation Impact
Citing Papers
Identification of Markers of Taxane Sensitivity Using Proteomic and Genomic Analyses of Breast Tumors from Patients Receiving Neoadjuvant Paclitaxel and Radiation
2010
Hematopoietic RIPK1 deficiency results in bone marrow failure caused by apoptosis and RIPK3-mediated necroptosis
2014
Differential Proteomics Identifies Protein Biomarkers That Predict Local Relapse of Head and Neck Squamous Cell Carcinomas
2009
Human pancreatic cancer cell exosomes, but not human normal cell exosomes, act as an initiator in cell transformation
2019
Co-operative and Hierarchical Binding of c-FLIP and Caspase-8: A Unified Model Defines How c-FLIP Isoforms Differentially Control Cell Fate
2016
Comprehensive genomic characterization of head and neck squamous cell carcinomas
2015 StandoutNature
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
2014 StandoutNobel
Cellular IAP proteins and LUBAC differentially regulate necrosome-associated RIP1 ubiquitination
2015
The Inflammasome Adaptor ASC Induces Procaspase-8 Death Effector Domain Filaments
2015
Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists
2024 StandoutScienceNobel
RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL
2015
The c-FLIPL Cleavage Product p43FLIP Promotes Activation of Extracellular Signal-regulated Kinase (ERK), Nuclear Factor κB (NF-κB), and Caspase-8 and T Cell Survival
2013
Translocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell death
2013
Clinical implications and utility of field cancerization
2007
MiR-424 and miR-155 deregulated expression in cytogenetically normal acute myeloid leukaemia: correlation with NPM1 and FLT3 mutation status
2012
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Biomolecular condensates: organizers of cellular biochemistry
2017 Standout
Cell death in chronic inflammation: breaking the cycle to treat rheumatic disease
2020
Combination of IAP antagonist and IFNγ activates novel caspase-10- and RIPK1-dependent cell death pathways
2017
It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival
2011
SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis
2011 Nature
Atypical ubiquitylation — the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages
2012
Physical Principles of Membrane Shape Regulation by the Glycocalyx
2019 StandoutNobel
Molecular techniques and genetic alterations in head and neck cancer
2008
Necroptosis and its role in inflammation
2015 StandoutNature
Mechanism and medical implications of mammalian autophagy
2018 Standout
Structural Architecture of the CARMA1/Bcl10/MALT1 Signalosome: Nucleation-Induced Filamentous Assembly
2013
Death by TNF: a road to inflammation
2022
The NLRP3 inflammasome: molecular activation and regulation to therapeutics
2019 Standout
TNFR1‐induced activation of the classical NF‐κB pathway
2011
The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease
2015 Standout
The C-terminal Domain of the Long Form of Cellular FLICE-inhibitory Protein (c-FLIPL) Inhibits the Interaction of the Caspase 8 Prodomain with the Receptor-interacting Protein 1 (RIP1) Death Domain and Regulates Caspase 8-dependent Nuclear Factor κB (NF-κB) Activation
2014
Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
2015 StandoutNature
Head and neck cancer
2008 Standout
IAPs: from caspase inhibitors to modulators of NF-κB, inflammation and cancer
2010
Molecular Adaptations Allow Dynein to Generate Large Collective Forces inside Cells
2013
NF-κB, the first quarter-century: remarkable progress and outstanding questions
2012 Standout
NF-κB-Independent Role of IKKα/IKKβ in Preventing RIPK1 Kinase-Dependent Apoptotic and Necroptotic Cell Death during TNF Signaling
2015
The biology and function of fibroblasts in cancer
2016 Standout
The E3 Ligase Parkin Maintains Mitochondrial Integrity by Increasing Linear Ubiquitination of NEMO
2013
Evaluation of cornulin, keratin 4, keratin 13 expression and grade of dysplasia for predicting malignant progression of oral leukoplakia
2009
The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible
2016 Standout
The molecular biology of head and neck cancer
2010 Standout
Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes
2014 Standout
A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape
2019 StandoutNobel
Shedding light on the cell biology of extracellular vesicles
2018 Standout
Necroptosis: The Release of Damage-Associated Molecular Patterns and Its Physiological Relevance
2013
Higher-Order Assemblies in a New Paradigm of Signal Transduction
2013
Identification of Putative Target Genes of the Transcription Factor RUNX2
2013 StandoutNobel
A long-awaited merger of the pathways mediating host defence and programmed cell death
2014
Necroptosis
2014
RIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibition
2013
Differential affinity of FLIP and procaspase 8 for FADD’s DED binding surfaces regulates DISC assembly
2014
Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells
2023 StandoutNobel
Integrin inactivators: balancing cellular functions in vitro and in vivo
2013
Emerging roles for Lys11-linked polyubiquitin in cellular regulation
2011
cIAPs Block Ripoptosome Formation, a RIP1/Caspase-8 Containing Intracellular Cell Death Complex Differentially Regulated by cFLIP Isoforms
2011
Nanoparticle-assisted optical tethering of endosomes reveals the cooperative function of dyneins in retrograde axonal transport
2015 StandoutNobel
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
2018 StandoutNobel
Exosomes in tumor microenvironment influence cancer progression and metastasis
2013
Cellular FLICE-inhibitory Protein (cFLIP) Isoforms Block CD95- and TRAIL Death Receptor-induced Gene Induction Irrespective of Processing of Caspase-8 or cFLIP in the Death-inducing Signaling Complex
2011
Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
2011 Standout
Regulation of tumour necrosis factor signalling: live or let die
2015
Linear ubiquitination in NF-κB signaling and inflammation: What we do understand and what we do not
2011
Viral infection and the evolution of caspase 8-regulated apoptotic and necrotic death pathways
2011
Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia
2013 Standout
Molecular imaging by mass spectrometry — looking beyond classical histology
2010
Caspase-8 tyrosine-380 phosphorylation inhibits CD95 DISC function by preventing procaspase-8 maturation and cycling within the complex
2016
Regulated necrosis: disease relevance and therapeutic opportunities
2016
RIPK1 Blocks Early Postnatal Lethality Mediated by Caspase-8 and RIPK3
2014
SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex
2011 Nature
Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
2017 StandoutNature
LUBAC-synthesized linear ubiquitin chains restrict cytosol-invading bacteria by activating autophagy and NF-κB
2017
Crosstalk in NF-κB signaling pathways
2011 Standout
Expanding TRAF function: TRAF3 as a tri-faced immune regulator
2011
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
2015 StandoutNature
SHARPIN is an endogenous inhibitor of β1-integrin activation
2011
The Ripoptosome, a Signaling Platform that Assembles in Response to Genotoxic Stress and Loss of IAPs
2011
Fas/CD95-Induced Chemokines Can Serve as “Find-Me” Signals for Apoptotic Cells
2013
Inflammasomes: mechanism of action, role in disease, and therapeutics
2015 Standout
Serum protein signature may improve detection of ductal carcinoma in situ of the breast
2009
Glycosylation in cancer: mechanisms and clinical implications
2015 Standout
Fluorescence-Based Sensors to Monitor Localization and Functions of Linear and K63-Linked Ubiquitin Chains in Cells
2012
Tumor Necrosis Factor Inhibits Spread of Hepatitis C Virus Among Liver Cells, Independent From Interferons
2017 StandoutNobel
Dispensable roles of Gsdmd and Ripk3 in sustaining IL-1β production and chronic inflammation in Th17-mediated autoimmune arthritis
2021 StandoutNobel
CLOCK deubiquitylation by USP8 inhibits CLK/CYC transcription in Drosophila
2012 StandoutNobel
The intersection of cell death and inflammasome activation
2016
Cryo-EM Structure of Caspase-8 Tandem DED Filament Reveals Assembly and Regulation Mechanisms of the Death-Inducing Signaling Complex
2016
Direction of actin flow dictates integrin LFA-1 orientation during leukocyte migration
2017 StandoutNobel
Linear ubiquitination of cytosolic Salmonella Typhimurium activates NF-κB and restricts bacterial proliferation
2017
Exosomes
2019 Standout
Control of Life-or-Death Decisions by RIP1 Kinase
2013
TNF and IL-1 exhibit distinct ubiquitin requirements for inducing NEMO–IKK supramolecular structures
2014
Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes
2016 Standout
Dynamics of CRISPR-Cas9 genome interrogation in living cells
2015 StandoutScienceNobel
Two independent pathways of regulated necrosis mediate ischemia–reperfusion injury
2013
Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses
2011 StandoutNobel
Extracellular vesicles including exosomes are mediators of signal transduction: Are they protective or pathogenic?
2014
Supramolecular Organisation of the Mitochondrial Respiratory Chain: A New Challenge for the Mechanism and Control of Oxidative Phosphorylation
2012
Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release
2014 Standout
Fundamental Mechanisms of Immune Checkpoint Blockade Therapy
2018 StandoutNobel
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Comprehensive comparison of large-scale tissue expression datasets
2015
Sharpin prevents skin inflammation by inhibiting TNFR1-induced keratinocyte apoptosis
2014
Novel cross-talk within the IKK family controls innate immunity
2011
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Ferroptosis as a target for protection against cardiomyopathy
2019 Standout
The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension
2012
Cutting Edge: RIP1 Kinase Activity Is Dispensable for Normal Development but Is a Key Regulator of Inflammation in SHARPIN-Deficient Mice
2014
The Ubiquitin Code
2012 Standout
Chemodynamic Therapy: Tumour Microenvironment‐Mediated Fenton and Fenton‐like Reactions
2018 Standout
The third group of the B7‐CD 28 immune checkpoint family: HHLA 2, TMIGD 2, B7x, and B7‐H3
2017
Tug-of-war between dissimilar teams of microtubule motors regulates transport and fission of endosomes
2009
The linear ubiquitin assembly complex (LUBAC) is essential for NLRP3 inflammasome activation
2014
Chemical Glycoproteomics
2016 StandoutNobel
Caspase‐8: regulating life and death
2017 Standout
Works of Uwe Warnken being referenced
Costimulatory Protein 4IgB7H3 Drives the Malignant Phenotype of Glioblastoma by Mediating Immune Escape and Invasiveness
2011
In-depth mass spectrometric mapping of the human vitreous proteome
2013
Modulation of oxidative phosphorylation machinery signifies a prime mode of anti-ageing mechanism of calorie restriction in male rat liver mitochondria
2009
Proteomic analysis reveals successive aberrations in protein expression from healthy mucosa to invasive head and neck cancer
2006
Molecular architecture of the DED chains at the DISC: regulation of procaspase-8 activation by short DED proteins c-FLIP and procaspase-8 prodomain
2015
Linear ubiquitination prevents inflammation and regulates immune signalling
2011 Nature
Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells
2011
Recruitment of the Linear Ubiquitin Chain Assembly Complex Stabilizes the TNF-R1 Signaling Complex and Is Required for TNF-Mediated Gene Induction
2009
Quantitative Proteomics Identify Novel miR-155 Target Proteins
2011
Stoichiometry of the CD95 Death-Inducing Signaling Complex: Experimental and Modeling Evidence for a Death Effector Domain Chain Model
2012
Subcellular protein extraction from human pancreatic cancer tissues
2009