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Citing Papers
Somatic action potentials are sufficient for late-phase LTP-related cell signaling
2002
Increased Susceptibility to Induction of Long-Term Depression and Long-Term Potentiation Reversal during Aging
1996
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein
1992 StandoutNatureNobel
Inhibition of Postsynaptic PKC or CaMKII Blocks Induction But Not Expression of LTP
1989 Science
Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein
1994 Standout
Characterization of the signaling interactions that promote the survival and growth of developing retinal ganglion cells in culture
1995
Synapse Specificity and Long-Term Information Storage
1997
Differences in Hippocampal Neuronal Population Responses to Modifications of an Environmental Context: Evidence for Distinct, Yet Complementary, Functions of CA3 and CA1 Ensembles
2004
Induction of CRE-Mediated Gene Expression by Stimuli That Generate Long-Lasting LTP in Area CA1 of the Hippocampus
1996
Signaling Networks
2000
Immediate-early genes, kindling and long-term potentiation
1989
Signaling from Synapse to Nucleus: Postsynaptic CREB Phosphorylation during Multiple Forms of Hippocampal Synaptic Plasticity
1996
CREB as a Memory Modulator: induced expression of a dCREB2 activator isoform enhances long-term memory in drosophila
1995
A Molecular Switch for the Consolidation of Long‐Term Memory: cAMP‐Inducible Gene Expression
1995 StandoutNobel
Postsynaptic then presynaptic protein kinase C activity may be necessary for long-term potentiation
1992
Fear memories require protein synthesis in the amygdala for reconsolidation after retrieval
2000 StandoutNature
Serotonin Induces Temporally and Mechanistically Distinct Phases of Persistent PKA Activity in Aplysia Sensory Neurons
1998
Activity-Dependent β-Adrenergic Modulation of Low Frequency Stimulation Induced LTP in the Hippocampal CA1 Region
1996
Inhibition of protein synthesis in the dentate gyrus, but not the entorhinal cortex, blocks maintenance of long-term potentiation in rats
1989
An essential role for postsynaptic calmodulin and protein kinase activity in long-term potentiation
1989 Nature
Genetic and Pharmacological Evidence for a Novel, Intermediate Phase of Long-Term Potentiation Suppressed by Calcineurin
1998 StandoutNobel
Inhibitors of calmodulin and protein kinase C block different phases of hippocampal long-term potentiation
1988
Delay-dependent impairment of a matching-to-place task with chronic and intrahippocampal infusion of the NMDA-antagonist D-AP5
1999
Independent rate and temporal coding in hippocampal pyramidal cells
2003 StandoutNatureNobel
Drosophila larval neuromuscular junction: Molecular components and mechanisms underlying synaptic plasticity
2000
The global record of memory in hippocampal neuronal activity
1999 Nature
Postsynaptic CAMP pathway gates early LTP in hippocampal CA1 region
1995
Involvement of a Postsynaptic Protein Kinase A Substrate in the Expression of Homosynaptic Long-Term Depression
1998
Recruitment of New Sites of Synaptic Transmission During the cAMP-Dependent Late Phase of LTP at CA3–CA1 Synapses in the Hippocampus
1997 StandoutNobel
Activation of p42 Mitogen-activated Protein Kinase in Hippocampal Long Term Potentiation
1996
Enhancement of Memory-Related Long-Term Facilitation by ApAF, a Novel Transcription Factor that Acts Downstream from Both CREB1 and CREB2
2000 StandoutNobel
PKA isoforms, neural pathways, and behaviour: making the connection
1997
A synaptic model of memory: long-term potentiation in the hippocampus
1993 StandoutNature
Temporally distinct pre- and post-synaptic mechanisms maintain long-term potentiation
1989 Nature
Maintenance of long-term potentiation in rat dentate gyrus requires protein synthesis but not messenger RNA synthesis immediately post-tetanization
1989
The CaM kinase II hypothesis for the storage of synaptic memory
1994
Frequency of gamma oscillations routes flow of information in the hippocampus
2009 StandoutNatureNobel
Activation of a K‐252b‐Sensitive Protein Kinase is Necessary for a Post‐Synaptic Phase of Long‐Term Potentiation in Area CA1 of Rat Hippocampus
1990
c-fos Protooncogene expression in rat hippocampus and entorhinal cortex following tetanic stimulation of the perforant path
1991
Genetic approaches to memory storage
1999
The role of immediate early genes in the stabilization of long-term potentiation
1991
Tissue Plasminogen Activator Contributes to the Late Phase of LTP and to Synaptic Growth in the Hippocampal Mossy Fiber Pathway
1998 StandoutNobel
Dissociation of hippocampus and caudate nucleus memory systems by posttraining intracerebral injection of dopamine agonists.
1991
Spatial and temporal changes in signal transduction pathways during LTP
1994
2-Amino-4-phosphonobutyrate selectively eliminates late phases of long-term potentiation in rat hippocampus
1989
Enhancement of extracellular protein concentrations during long-term potentiation in the rat hippocampal slice
1992
Synapse-Specific, Long-Term Facilitation of Aplysia Sensory to Motor Synapses: A Function for Local Protein Synthesis in Memory Storage
1997 StandoutNobel
cAMP contributes to mossy fiber LTP by initiating both a covalently mediated early phase and macromolecular synthesis-dependent late phase
1994 StandoutNobel
Persistent protein kinase activity underlying long-term potentiation
1988 Nature
A genetic test of the effects of mutations in PKA on mossy fiber ltp and its relation to spatial and contextual learning
1995
Long-term potentiation in the hippocampus is blocked by tyrosine kinase inhibitors
1991 StandoutNatureNobel
The Hippocampus, Memory, and Place Cells
1999
CREB and the formation of long-term memory
1996
The role of nitric oxide in hippocampal long-term potentiation
1992
Local protein synthesis and its role in synapse-specific plasticity
2000 StandoutNobel
CREB: A mediator of long-term memory from mollusks to mammals
1994
Induction of a dominant negative CREB transgene specifically blocks long-term memory in Drosophila
1994
Can molecules explain long-term potentiation?
1999
Long-term plasticity in hippocampal place-cell representation of environmental geometry
2002 StandoutNatureNobel
Ultrastructural Plasticity of Excitatory Synapses
1997
Induction of Fos-like immunoreactivity and the maintenance of long-term potentiation in the dentate gyrus of unanesthetized rats
1990
A Late Phase of Cerebellar Long-Term Depression Requires Activation of CaMKIV and CREB
1999
Stimulation of cAMP response element (CRE)-mediated transcription during contextual learning
1998
Postsynaptic factors control the duration of synaptic enhancement in area CA1 of the hippocampus
1991
A persistent postsynaptic modification mediates long-term potentiation in the hippocampus
1988
Arachidonic acid induces a long-term activity-dependent enhancement of synaptic transmission in the hippocampus
1989 Nature
Cyclic AMP induces functional presynaptic boutons in hippocampal CA3–CA1 neuronal cultures
1999
Cognitive Neuroscience and the Study of Memory
1998
Long-term potentiation: What's learning got to do with it?
1997
Recombinant BDNF Rescues Deficits in Basal Synaptic Transmission and Hippocampal LTP in BDNF Knockout Mice
1996 StandoutNobel
Reversible neural inactivation reveals hippocampal participation in several memory processes
1999
The role of Rab3A in neurotransmitter release
1994 StandoutNatureNobel
Genetic Demonstration of a Role for PKA in the Late Phase of LTP and in Hippocampus-Based Long-Term Memory
1997 StandoutNobel
Genetic Dissection of Structural and Functional Components of Synaptic Plasticity. II. Fasciclin II Controls Presynaptic Structural Plasticity
1996
Role of guanylyl cyclase and cGMP-dependent protein kinase in long-term potentiation
1994 StandoutNatureNobel
A Protein Synthesis–Dependent Late Phase of Cerebellar Long-Term Depression
1996
Staurosporine impairs both short-term and long-term potentiation in the dentate gyrus in vitro
1994
MAP Kinase Translocates into the Nucleus of the Presynaptic Cell and Is Required for Long-Term Facilitation in Aplysia
1997 StandoutNobel
Hippocampal protein kinase C activity is reduced in poor spatial learners
1990
A Transient, Neuron-Wide Form of CREB-Mediated Long-Term Facilitation Can Be Stabilized at Specific Synapses by Local Protein Synthesis
1999 StandoutNobel
Transgenic approaches to cognition
1995 StandoutNobel
Age-related defects in spatial memory are correlated with defects in the late phase of hippocampal long-term potentiation in vitro and are attenuated by drugs that enhance the cAMP signaling pathway
1999 StandoutNobel
Rolipram, a type IV-specific phosphodiesterase inhibitor, facilitates the establishment of long-lasting long-term potentiation and improves memory
1998 StandoutNobel
Pattern Separation in the Dentate Gyrus and CA3 of the Hippocampus
2007 StandoutScienceNobel
Increased transmitter release at excitatory synapses produced by direct activation of adenylate cyclase in rat hippocampal slices
1994
Protein synthesis-dependent formation of protein kinase Mzeta in long- term potentiation
1996
Novelty acquisition is associated with induction of hippocampal long-term depression
1999
A Requirement for Local Protein Synthesis in Neurotrophin-Induced Hippocampal Synaptic Plasticity
1996 Science
Long-Lasting Neurotrophin-Induced Enhancement of Synaptic Transmission in the Adult Hippocampus
1995 Science
Pretraining Prevents Spatial Learning Impairment after Saturation of Hippocampal Long-Term Potentiation
1999 StandoutNobel
Mediation of Hippocampal Mossy Fiber Long-Term Potentiation by Cyclic AMP
1994 Science
Memory Consolidation of Auditory Pavlovian Fear Conditioning Requires Protein Synthesis and Protein Kinase A in the Amygdala
2000
Activity-dependent regulation of synaptic clustering in a hippocampal culture system
1999
Role for Rapid Dendritic Protein Synthesis in Hippocampal mGluR-Dependent Long-Term Depression
2000 Science
Postsynaptic protein kinase C essential to induction and maintenance of long-term potentiation in the hippocampal CA1 region.
1992
Capture of a protein synthesis-dependent component of long-term depression
2000 StandoutNobel
Gating by Cyclic AMP: Expanded Role for an Old Signaling Pathway
1996 Science
Postsynaptic Application of a Peptide Inhibitor of cAMP-Dependent Protein Kinase Blocks Expression of Long-Lasting Synaptic Potentiation in Hippocampal Neurons
2003
Memory--a Century of Consolidation
2000 StandoutScience
Involvement of hippocampal cAMP/cAMP-dependent protein kinase signaling pathways in a late memory consolidation phase of aversively motivated learning in rats
1997
Impaired Long-Term Potentiation, Spatial Learning, and Hippocampal Development in fyn Mutant Mice
1992 StandoutScienceNobel
A Family of cAMP-Binding Proteins That Directly Activate Rap1
1998 StandoutScience
Requirement of a Critical Period of Transcription for Induction of a Late Phase of LTP
1994 StandoutScienceNobel
A Family of AMPA-Selective Glutamate Receptors
1990 StandoutScienceNobel
Accumulation of Hippocampal Place Fields at the Goal Location in an Annular Watermaze Task
2001 StandoutNobel
Modulation of Both the Early and the Late Phase of Mossy Fiber LTP by the Activation of β-Adrenergic Receptors
1996 StandoutNobel
Abnormal Hippocampal Spatial Representations in αCaMKII T286A and CREB αΔ− Mice
1998 Science
Mice lacking the gene encoding tissue-type plasminogen activator show a selective interference with late-phase long-term potentiation in both Schaffer collateral and mossy fiber pathways.
1996
Induction of long-term facilitation in Aplysia sensory neurons by local application of serotonin to remote synapses.
1993 StandoutNobel
Importance of AMPA Receptors for Hippocampal Synaptic Plasticity But Not for Spatial Learning
1999 ScienceNobel
Neural Science
2000 StandoutNobel
CREB AND MEMORY
1998
Functional Expression of the Heteromeric “Olfactory” Cyclic Nucleotide-Gated Channel in the Hippocampus: A Potential Effector of Synaptic Plasticity in Brain Neurons
1997
Control of Memory Formation Through Regulated Expression of a CaMKII Transgene
1996 StandoutScienceNobel
Bruchpilot Promotes Active Zone Assembly, Ca 2+ Channel Clustering, and Vesicle Release
2006 StandoutScienceNobel
Different Training Procedures Recruit Either One or Two Critical Periods for Contextual Memory Consolidation, Each of Which Requires Protein Synthesis and PKA
1998 StandoutNobel
The 3′-untranslated region of CaMKIIα is a cis-acting signal for the localization and translation of mRNA in dendrites
1996 StandoutNobel
An Extracellular Proteolytic Cascade Promotes Neuronal Degeneration in the Mouse Hippocampus
1997
Integrating information at single synaptic connections.
1995
Altered behavior and long-term potentiation in type I adenylyl cyclase mutant mice.
1995
Repeated pulses of serotonin required for long-term facilitation activate mitogen-activated protein kinase in sensory neurons of Aplysia
1998 StandoutNobel
Hippocampal long-term depression and depotentiation are defective in mice carrying a targeted disruption of the gene encoding the RI beta subunit of cAMP-dependent protein kinase.
1995 StandoutNobel
Interactive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein, with homology to Eag and cyclic nucleotide-gated channels
1997 StandoutNobel
Flip and Flop: A Cell-Specific Functional Switch in Glutamate-Operated Channels of the CNS
1990 StandoutScienceNobel
Inhibition of protein kinase C blocks two components of LTP persistence, leaving initial potentiation intact
1990
Molecular Mechanisms of Long-Term Potentiation in the Insular CortexIn Vivo
1999
Parallel Instabilities of Long-Term Potentiation, Place Cells, and Learning Caused by Decreased Protein Kinase A Activity
2000 StandoutNobel
The Molecular Biology of Memory Storage: A Dialogue Between Genes and Synapses
2001 StandoutScienceNobel
GENE DISCOVERY INDROSOPHILA: New Insights for Learning and Memory
1998
Toward a molecular definition of long-term memory storage
1996 StandoutNobel
A biochemist's view of long-term potentiation.
1996
Memory Consolidation for Contextual and Auditory Fear Conditioning Is Dependent on Protein Synthesis, PKA, and MAP Kinase
1999
Stability in Synapse Number and Size at 2 Hr after Long-Term Potentiation in Hippocampal Area CA1
1998
Synaptic Plasticity and Memory: An Evaluation of the Hypothesis
2000 Standout
GENE TARGETING AND THE BIOLOGY OF LEARNING AND MEMORY
1997
The impact of postsynaptic calcium on synaptic transmission — its role in long-term potentiation
1989
Recruitment of long-lasting and protein kinase A-dependent long-term potentiation in the CA1 region of hippocampus requires repeated tetanization.
1994 StandoutNobel
Long-lasting forms of synaptic potentiation in the mammalian hippocampus.
1996
Long-term potentiation and the induction of c-fos mRNA and proteins in the dentate gyrus of unanesthetized rats
1989
A Macromolecular Synthesis-Dependent Late Phase of Long-Term Potentiation Requiring cAMP in the Medial Perforant Pathway of Rat Hippocampal Slices
1996 StandoutNobel
Genetic evidence for a protein-kinase-A-mediated presynaptic component in NMDA-receptor-dependent forms of long-term synaptic potentiation
2005 StandoutNobel
Impaired hippocampal plasticity in mice lacking the Cbeta1 catalytic subunit of cAMP-dependent protein kinase.
1996 StandoutNobel
Transduction of Receptor Signals by ß-Arrestins
2005 StandoutScienceNobel
SynCAM, a Synaptic Adhesion Molecule That Drives Synapse Assembly
2002 StandoutScienceNobel
Works of Uwe Frey being referenced
The effect of dopaminergic D1 receptor blockade during tetanization on the expression of long-term potentiation in the rat CA1 region in vitro
1991
Synaptic tagging and long-term potentiation
1997 Nature
Different Mechanisms and Multiple Stages of LTP
1990
Synaptic tagging: implications for late maintenance of hippocampal long-term potentiation
1998
Polymyxin B, an inhibitor of protein kinase C, prevents the maintenance of synaptic long-term potentiation in hippocampal CA1 neurons
1988
Anisomycin, an inhibitor of protein synthesis, blocks late phases of LTP phenomena in the hippocampal CA1 region in vitro
1988
Weak before strong: dissociating synaptic tagging and plasticity-factor accounts of late-LTP
1998
Long-term potentiation induced in dendrites separated from rat's CA1 pyramidal somata does not establish a late phase
1989
Asymptotic hippocampal long-term potentiation in rats does not preclude additional potentiation at later phases
1995
Dopaminergic antagonists prevent long-term maintenance of posttetanic LTP in the CA1 region of rat hippocampal slices
1990
Domperidone, an inhibitor of the D2-receptor, blocks a late phase of an electrically induced long-term potentiation in the CA1-region in rats.
1989
Hippocampal synaptic plasticity: role in spatial learning or the automatic recording of attended experience?
1997
Effects of cAMP Simulate a Late Stage of LTP in Hippocampal CA1 Neurons
1993 Science
Deficits in Memory Tasks of Mice with CREB Mutations Depend on Gene Dosage
1998
Endogenous Serine Protease Inhibitor Modulates Epileptic Activity and Hippocampal Long-Term Potentiation
1997
A different form of long-lasting potentiation revealed in tissue plasminogen activator mutant mice
1996
Somatodendritic expression of an immediate early gene is regulated by synaptic activity.
1995
Influence of actinomycin D, a RNA synthesis inhibitor, on long‐term potentiation in rat hippocampal neurons in vivo and in vitro.
1996