Citation Impact
Citing Papers
Lys63-Linked Polyubiquitination of IRAK-1 Is Required for Interleukin-1 Receptor- and Toll-Like Receptor-Mediated NF-κB Activation
2008
Developmental Decline in Neuronal Regeneration by the Progressive Change of Two Intrinsic Timers
2013 StandoutScienceNobel
The 2016 revision of the World Health Organization classification of lymphoid neoplasms
2016 Standout
The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins
2013 StandoutScienceNobel
Comprehensive genomic characterization of head and neck squamous cell carcinomas
2015 StandoutNature
Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution
2024 StandoutNobel
The let-7 target gene mouse lin-41 is a stem cell specific E3 ubiquitin ligase for the miRNA pathway protein Ago2
2009
It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival
2011
The mechanisms of Hedgehog signalling and its roles in development and disease
2013 Standout
NF-κB signaling in inflammation
2017 Standout
The NF-κB regulator MALT1 determines the encephalitogenic potential of Th17 cells
2012
Necroptosis and its role in inflammation
2015 StandoutNature
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
2010 Standout
Structural Architecture of the CARMA1/Bcl10/MALT1 Signalosome: Nucleation-Induced Filamentous Assembly
2013
Deubiquitinases in the regulation of NF-κB signaling
2010
Regulation of microRNA biogenesis
2014 Standout
Shared Principles in NF-κB Signaling
2008 Standout
Hypoxia and Inflammation
2011 Standout
IAPs: from caspase inhibitors to modulators of NF-κB, inflammation and cancer
2010
NF-κB, the first quarter-century: remarkable progress and outstanding questions
2012 Standout
Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity
2011 Standout
The tumour microenvironment after radiotherapy: mechanisms of resistance and recurrence
2015 Standout
Pattern Recognition Receptors and Inflammation
2010 Standout
Commitment to the Regulatory T Cell Lineage Requires CARMA1 in the Thymus but Not in the Periphery
2009 StandoutNobel
The Signaling Adaptor p62 Is an Important NF-κB Mediator in Tumorigenesis
2008
Structural Basis for Recognition of Diubiquitins by NEMO
2009
The molecular biology of head and neck cancer
2010 Standout
Antigen-Receptor Signaling to Nuclear Factor κB
2006
Unified Polymerization Mechanism for the Assembly of ASC-Dependent Inflammasomes
2014 Standout
The CARMA1 signalosome links the signalling machinery of adaptive and innate immunity in lymphocytes
2006
Intracellular Toll-like Receptors
2010 StandoutNobel
Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children
2016 Standout
FOXP3 and scurfy: how it all began
2014 StandoutNobel
c‐Rel is crucial for the induction of Foxp3+ regulatory CD4+ T cells but not TH17 cells
2010
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Identification of Putative Target Genes of the Transcription Factor RUNX2
2013 StandoutNobel
Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation
2009 Standout
Breaking the chains: structure and function of the deubiquitinases
2009 Standout
Disruption of Fnip1 Reveals a Metabolic Checkpoint Controlling B Lymphocyte Development
2012 StandoutNobel
The widespread regulation of microRNA biogenesis, function and decay
2010 Standout
Deubiquitylation and regulation of the immune response
2008
Immunity, Inflammation, and Cancer
2010 Standout
Return to homeostasis: downregulation of NF-κB responses
2011
TCR signaling to NF-κB and mTORC1: Expanding roles of the CARMA1 complex
2015
Oncogenic Activation of NF- B
2010
Signalling through C-type lectin receptors: shaping immune responses
2009
NF-κB Is a Negative Regulator of IL-1β Secretion as Revealed by Genetic and Pharmacological Inhibition of IKKβ
2007
Death receptor signal transducers: nodes of coordination in immune signaling networks
2009
Selective C-Rel Activation via Malt1 Controls Anti-Fungal TH-17 Immunity by Dectin-1 and Dectin-2
2011
Roles of the NF- B Pathway in Lymphocyte Development and Function
2009
Viral infection and the evolution of caspase 8-regulated apoptotic and necrotic death pathways
2011
Diffuse large B-cell lymphoma—treatment approaches in the molecular era
2013
T cell antigen receptor stimulation induces MALT1 paracaspase–mediated cleavage of the NF-κB inhibitor A20
2008
Hedgehog beyond medulloblastoma and basal cell carcinoma
2010
Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans
2008
Sterile inflammation: sensing and reacting to damage
2010 Standout
Molecular mechanisms of necroptosis: an ordered cellular explosion
2010 Standout
Genetics and pathogenesis of inflammatory bowel disease
2011 StandoutNature
IκB kinase complexes: gateways to NF-κB activation and transcription
2006
c‐Rel but not NF‐κB1 is important for T regulatory cell development
2010
Ubiquitin signaling in immune responses
2016
Clonal evolution in cancer
2012 StandoutNature
New insights into NF-κB regulation and function
2008
Ubiquitylation in innate and adaptive immunity
2009 Nature
Termination of autophagy and reformation of lysosomes regulated by mTOR
2010 StandoutNature
Caspase-8 in cancer biology and therapy
2008
Phosphorylation of SNAP-23 by IκB Kinase 2 Regulates Mast Cell Degranulation
2008
Casein kinase 1α governs antigen-receptor-induced NF-κB activation and human lymphoma cell survival
2008 Nature
AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint
2008 Standout
A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis
2011
NF-κB, inflammation, immunity and cancer: coming of age
2018 Standout
Integrating cell-signalling pathways with NF-κB and IKK function
2006 Standout
Immunogenic cell death and DAMPs in cancer therapy
2012 Standout
Cancer genomics: from discovery science to personalized medicine
2011
Role of Hydrogen Peroxide in NF-κB Activation: From Inducer to Modulator
2009
FADD Deficiency Impairs Early Hematopoiesis in the Bone Marrow
2010
A mutation of Ikbkg causes immune deficiency without impairing degradation of IκBα
2010 StandoutNobel
Regulation and Function of NF-κB Transcription Factors in the Immune System
2009 Standout
B Cell Signaling and Fate Decision
2009
Phosphorylation of Bcl10 Negatively Regulates T-Cell Receptor-Mediated NF-κB Activation
2007
Paracaspase MALT1 Deficiency Protects Mice from Autoimmune-Mediated Demyelination
2013
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
2008 StandoutNature
Immunological and Inflammatory Functions of the Interleukin-1 Family
2009 Standout
Necroptosis in health and diseases
2014
The Role of Ubiquitin in NF-κB Regulatory Pathways
2009
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
A20: linking a complex regulator of ubiquitylation to immunity and human disease
2012
Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum
2011 StandoutScience
Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation
2020 StandoutNobel
IκB Kinase β Phosphorylates the K63 Deubiquitinase A20 To Cause Feedback Inhibition of the NF-κB Pathway
2007
CD8 T Cell-Intrinsic GITR Is Required for T Cell Clonal Expansion and Mouse Survival following Severe Influenza Infection
2010 StandoutNobel
IκB kinase β–induced phosphorylation of CARMA1 contributes to CARMA1–Bcl10–MALT1 complex formation in B cells
2007
The Ubiquitin Code
2012 Standout
Ubiquitin in NF-κB Signaling
2009
Lenalidomide efficacy in activated B ‐cell‐like subtype diffuse large B ‐cell lymphoma is dependent upon IRF 4 and cereblon expression
2012
Caspase‐8: regulating life and death
2017 Standout
Works of Uta Ferch being referenced
The fusion kinase ITK-SYK mimics a T cell receptor signal and drives oncogenesis in conditional mouse models of peripheral T cell lymphoma
2010
Bcl10/Malt1 Signaling Is Essential for TCR-Induced NF-κB Activation in Thymocytes but Dispensable for Positive or Negative Selection
2007
Essential Role for IκB Kinase β in Remodeling Carma1-Bcl10-Malt1 Complexes upon T Cell Activation
2006
Malt1 ubiquitination triggers NF‐κB signaling upon T‐cell activation
2007
MALT1 directs B cell receptor–induced canonical nuclear factor-κB signaling selectively to the c-Rel subunit
2007
A model for PTCH1/Ptch1-associated tumors comprising mutational inactivation and gene silencing.
2005
Inhibition of MALT1 protease activity is selectively toxic for activated B cell–like diffuse large B cell lymphoma cells
2009
A20 Negatively Regulates T Cell Receptor Signaling to NF-κB by Cleaving Malt1 Ubiquitin Chains
2009
Caspase-8 and c-FLIPL Associate in Lipid Rafts with NF-κB Adaptors during T Cell Activation
2007
Bcl10 Controls TCR- and FcγR-Induced Actin Polymerization
2007