Standout Papers

Regulation of Mammalian Autophagy in Physiology and Pathophysiology 2010 2026 2015 2020 1.4k
  1. Regulation of Mammalian Autophagy in Physiology and Pathophysiology (2010)
    Brinda Ravikumar, Sovan Sarkar et al. Physiological Reviews

Citation Impact

Citing Papers

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Synaptic Pruning by Microglia Is Necessary for Normal Brain Development
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mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists
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The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins
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Frequent Mutations of Chromatin Remodeling Gene ARID1A in Ovarian Clear Cell Carcinoma
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Delayed Stabilization of Dendritic Spines in Fragile X Mice
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Autophagosome Precursor Maturation Requires Homotypic Fusion
2011
Elongation Factor 2 and Fragile X Mental Retardation Protein Control the Dynamic Translation of Arc/Arg3.1 Essential for mGluR-LTD
2008
The Thermotolerant Yeast Kluyveromyces marxianus Is a Useful Organism for Structural and Biochemical Studies of Autophagy
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Retinal ganglion cell death is triggered by paraptosis via reactive oxygen species production: A brief literature review presenting a novel hypothesis in glaucoma pathology
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ω-6 Polyunsaturated fatty acids extend life span through the activation of autophagy
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The Role of Autophagy in Parkinson's Disease
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Signals from the lysosome: a control centre for cellular clearance and energy metabolism
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Protein phosphatase 2A regulatory subunits and cancer
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Exosomes and Autophagy: Coordinated Mechanisms for the Maintenance of Cellular Fitness
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Autophagy and Cancer
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Functions of autophagy in normal and diseased liver
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Laforin, the most common protein mutated in Lafora disease, regulates autophagy
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The Spliceosome: Design Principles of a Dynamic RNP Machine
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mTOR signaling: At the crossroads of plasticity, memory and disease
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Oxidative stress, neurodegeneration, and the balance of protein degradation and protein synthesis
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Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets
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Autophagy promotes survival of retinal ganglion cells after optic nerve axotomy in mice
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Translational Control of Long-Lasting Synaptic Plasticity and Memory
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The Role of Ionotropic Glutamate Receptors in Childhood Neurodevelopmental Disorders: Autism Spectrum Disorders and Fragile X Syndrome
2014
The cellular pathology of lysosomal diseases
2011
Autophagy: Renovation of Cells and Tissues
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The emerging role of synaptic cell-adhesion pathways in the pathogenesis of autism spectrum disorders
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Biological Functions of Autophagy Genes: A Disease Perspective
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Decoding ALS: from genes to mechanism
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DGAT1-Dependent Lipid Droplet Biogenesis Protects Mitochondrial Function during Starvation-Induced Autophagy
2017
NMDA receptor blockade at rest triggers rapid behavioural antidepressant responses
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Cytoplasmic ribonucleoprotein (RNP) bodies and their relationship to GW/P bodies
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mTOR Signaling in Growth, Metabolism, and Disease
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Chemical modulators of autophagy as biological probes and potential therapeutics
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Mechanisms of Autophagosome Biogenesis
2012
Pumping RNA: nuclear bodybuilding along the RNP pipeline
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Lysosomal positioning coordinates cellular nutrient responses
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On the Dependency of Cellular Protein Levels on mRNA Abundance
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Autophagy in Human Health and Disease
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Phase transitions in the assembly of multivalent signalling proteins
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The Beclin 1 network regulates autophagy and apoptosis
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Variants in the autophagy-related gene IRGM confer susceptibility to non-alcoholic fatty liver disease by modulating lipophagy
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The Fragile X Syndrome Protein Represses Activity-Dependent Translation through CYFIP1, a New 4E-BP
2008
ATG4B/autophagin-1 regulates intestinal homeostasis and protects mice from experimental colitis
2013
Autophagy modulation as a potential therapeutic target for diverse diseases
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The Autophagy-related Protein Kinase Atg1 Interacts with the Ubiquitin-like Protein Atg8 via the Atg8 Family Interacting Motif to Facilitate Autophagosome Formation
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Autophagy and Aging
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Coilin-dependent snRNP assembly is essential for zebrafish embryogenesis
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Congenital disorders of autophagy: an emerging novel class of inborn errors of neuro-metabolism
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Non-coding RNAs: lessons from the small nuclear and small nucleolar RNAs
2007
A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
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Control of autophagy as a therapy for neurodegenerative disease
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Neuronal nicotinic receptors: from structure to pathology
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AKT/PKB Signaling: Navigating the Network
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Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
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The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis
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Chemical Inducers of Autophagy That Enhance the Clearance of Mutant Proteins in Neurodegenerative Diseases
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Quantitative Proteomic Analysis of Cellular Protein Modulation upon Inhibition of the NEDD8-Activating Enzyme by MLN4924
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The Hallmarks of Aging
2013 Standout
Macrophage Cytokines: Involvement in Immunity and Infectious Diseases
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Lysosomal basification and decreased autophagic flux in oxidatively stressed trabecular meshwork cells
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Autophagy-related Protein 32 Acts as Autophagic Degron and Directly Initiates Mitophagy
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A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease
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TMEM41B Is a Pan-flavivirus Host Factor
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Translational control of localized mRNAs: restricting protein synthesis in space and time
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Atg9 Vesicles Recruit Vesicle-tethering Proteins Trs85 and Ypt1 to the Autophagosome Formation Site
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Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21
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Elucidation of AMPA receptor–stargazin complexes by cryo–electron microscopy
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Inflammaging: disturbed interplay between autophagy and inflammasomes
2012
Spliceosomal Small Nuclear Ribonucleoprotein Particles Repeatedly Cycle through Cajal Bodies
2008
RNA–protein analysis using a conditional CRISPR nuclease
2013 StandoutNobel
The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis
2012
Biogenesis and Cargo Selectivity of Autophagosomes
2011
Membrane proteomics of phagosomes suggests a connection to autophagy
2008 StandoutNobel
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function
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Spermidine in health and disease
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Dephosphorylation of survival motor neurons (SMN) by PPM1G/PP2Cγ governs Cajal body localization and stability of the SMN complex
2007
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
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Walking the tightrope: proteostasis and neurodegenerative disease
2016
Atg13 HORMA domain recruits Atg9 vesicles during autophagosome formation
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Mechanisms of Diabetic Complications
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Discovery of autophagy modulators through the construction of a high-content screening platform via monitoring of lipid droplets
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Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers
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Generation and Detection of Reactive Oxygen Species in Photocatalysis
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Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
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Liquid phase condensation in cell physiology and disease
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Lenalidomide efficacy in activated B‐cell‐like subtype diffuse large B‐cell lymphoma is dependent upon IRF4 and cereblon expression
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Autophagy in Health and Disease: A Double-Edged Sword
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Works of Usha Narayanan being referenced

NEDD8-Targeting Drug MLN4924 Elicits DNA Rereplication by Stabilizing Cdt1 in S Phase, Triggering Checkpoint Activation, Apoptosis, and Senescence in Cancer Cells
2010
Inhibition of NEDD8-Activating Enzyme Induces Rereplication and Apoptosis in Human Tumor Cells Consistent with Deregulating CDT1 Turnover
2011
FMRP Phosphorylation Reveals an Immediate-Early Signaling Pathway Triggered by Group I mGluR and Mediated by PP2A
2007
S6K1 Phosphorylates and Regulates Fragile X Mental Retardation Protein (FMRP) with the Neuronal Protein Synthesis-dependent Mammalian Target of Rapamycin (mTOR) Signaling Cascade
2008
Coupled In Vitro Import of U snRNPs and SMN, the Spinal Muscular Atrophy Protein
2004
Nicotinic receptor expression following nicotine exposure via maternal milk
2002
SMN, the spinal muscular atrophy protein, forms a pre-import snRNP complex with snurportin1 and importin beta
2002
Interaction between the small‐nuclear‐RNA cap hypermethylase and the spinal muscular atrophy protein, survival of motor neuron
2003
Fragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptors
2007
MLN4924, a NEDD8-activating enzyme inhibitor, is active in diffuse large B-cell lymphoma models: rationale for treatment of NF-κB–dependent lymphoma
2010
Mammalian macroautophagy at a glance
2009
Regulation of Mammalian Autophagy in Physiology and Pathophysiology
2010 Standout
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