Citation Impact
Citing Papers
Supercoil Sequencing: A Fast and Simple Method for Sequencing Plasmid DNA
1985 Standout
Notch signalling controls pancreatic cell differentiation
1999 StandoutNatureNobel
Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185
1986
Differential activation of yeast adenylate cyclase by wild type and mutant RAS proteins
1985
Genetic variability of the AIDS virus: Nucleotide sequence analysis of two isolates from African patients
1986 StandoutNobel
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
nhl-2 Modulates MicroRNA Activity in Caenorhabditis elegans
2009 StandoutNobel
Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/NeuroD-deficient mice
1997
The Hallmarks of Cancer
2000 Standout
Gene Ontology: tool for the unification of biology
2000 Standout
Linkage of a prion protein missense variant to Gerstmann–Sträussler syndrome
1989 StandoutNatureNobel
All ras proteins are polyisoprenylated but only some are palmitoylated
1989 Standout
UCSF Chimera—A visualization system for exploratory research and analysis
2004 Standout
Reduced expression of neural cell adhesion molecule induces metastatic dissemination of pancreatic β tumor cells
1999
Caenorhabditis elegans ras gene let-60 acts as a switch in the pathway of vulval induction
1990 Nature
K-ras is an essential gene in the mouse with partial functional overlap with N-ras
1997
The drosophila gastrulation gene concertina encodes a Gα-like protein
1991 StandoutNobel
The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex
1995 StandoutNobel
Isoprenylation in regulation of signal transduction by G-protein-coupled receptor kinases
1992 StandoutNatureNobel
A novel potent vasoconstrictor peptide produced by vascular endothelial cells
1988 StandoutNature
Yeast: an Experimental Organism for Modern Biology
1988 Science
Multiple intercellular signalling systems control the development of the Caenorhabditis elegans vulva
1991 StandoutNatureNobel
The ras gene family and human carcinogenesis
1988
An FGF receptor signaling pathway is required for the normal cell migrations of the sex myoblasts in C. elegans hermaphrodites
1995 StandoutNobel
Regulation by HIV Rev depends upon recognition of splice sites
1989 StandoutNobel
Transcriptional activation by the v-myb oncogene and its cellular progenitor, c-myb
1989 StandoutNobel
EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection
2016 StandoutNobel
Universal control mechanism regulating onset of M-phase
1990 StandoutNatureNobel
Farnesol modification of Kirsten-ras exon 4B protein is essential for transformation.
1990
Degradation of nuclear oncoproteins by the ubiquitin system in vitro.
1991 StandoutNobel
Transformation of quail embryo fibroblasts by a retrovirus carrying a normal human c-myc gene.
1986
Homologies Between Signal Transducing G Proteins and ras Gene Products
1984 StandoutScienceNobel
Cellular Oncogenes and Multistep Carcinogenesis
1983 Science
Small GTP-Binding Proteins
2001 Standout
Genes in S. cerevisiae encoding proteins with domains homologous to the mammalian ras proteins
1984
Requirement of either of a pair of ras-related genes of Saccharomyces cerevisiae for spore viability
1984 Nature
The nucleotide sequence and the tissue-specific expression of Drosophila c-src
1985 StandoutNobel
Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/neuOncogene
1987 StandoutScience
In yeast, RAS proteins are controlling elements of adenylate cyclase
1985
Structure and organization of the human Ki-ras proto-oncogene and a related processed pseudogene
1983 Nature
The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas
1998
Genome organization and transactivation of the human immunodeficiency virus type 2
1987 StandoutNatureNobel
THE MOLECULAR GENETICS OF CELLULAR ONCOGENES
1984
Amplification of N- myc in Untreated Human Neuroblastomas Correlates with Advanced Disease Stage
1984 StandoutScienceNobel
Isolation of the proto-oncogene c-myb from D. melanogaster
1985 StandoutNobel
Biological properties of human c-Ha-ras1 genes mutated at codon 12
1984 Nature
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Antisera of designed specificity for subunits of guanine nucleotide-binding regulatory proteins.
1986 StandoutNobel
A human gastric carcinoma contains a single mutated and an amplified normal allele of the Ki-rasoncogene
1986
Ha-ras proteins exhibit GTPase activity: point mutations that activate Ha-ras gene products result in decreased GTPase activity.
1985
Phorbol ester- and protein kinase C-mediated phosphorylation of the cellular Kirsten ras gene product.
1987
Structural Determinants of Ion Flow Through Recombinant Glutamate Receptor Channels
1991 StandoutScienceNobel
Oncogenes: Yeast aids cancer research
1985 StandoutNatureNobel
Induction of Membrane Ruffling and Fluid-Phase Pinocytosis in Quiescent Fibroblasts by ras Proteins
1986 Science
A novel ras-related gene family
1985 StandoutNobel
Oncogene amplification during tumorigenesis of established rat fibroblasts reversibly transformed by activated human ras oncogenes.
1986
The ral gene: a new ras related gene isolated by the use of a synthetic probe.
1986
Evolution of tumours and the impact of molecular oncology
1985 Nature
Enhanced expression of the human gene N-myc consequent to amplification of DNA may contribute to malignant progression of neuroblastoma.
1984 StandoutNobel
Nucleic acid structure and expression of the human AIDS/lymphadenopathy retrovirus
1985 Nature
Structure-Based Strategies for Drug Design and Discovery
1992 Science
Harvey ras genes transform without mutant codons, apparently activated by truncation of a 5' exon (exon -1).
1986
Functional homology of mammalian and yeast RAS genes
1985
Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin
1986 StandoutNatureNobel
A lymphocyte-specific protein-tyrosine kinase gene is rearranged and overexpressed in the murine T cell lymphoma LSTRA
1985 StandoutNobel
Genetic analysis of yeast RAS1 and RAS2 genes
1984
Comparative biochemical properties of normal and activated human ras p21 protein
1984 Nature
Characterization of the terminal regions of hepatitis C viral RNA: identification of conserved sequences in the 5' untranslated region and poly(A) tails at the 3' end.
1991 StandoutNobel
The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans
1995 StandoutNobel
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
The product of ras is a GTPase and the T24 oncogenic mutant is deficient in this activity
1984 Nature
Suppression of tumorigenicity with continued expression of the c-Ha-ras oncogene in EJ bladder carcinoma-human fibroblast hybrid cells.
1986
Molecular Cloning of Complementary DNA for the Alpha Subunit of the G Protein that Stimulates Adenylate Cyclase
1985 StandoutScienceNobel
The ARD1 gene of yeast functions in the switch between the mitotic cell cycle and alternative developmental pathways
1985 StandoutNobel
A cellular gene encodes scrapie PrP 27-30 protein
1985 StandoutNobel
Age- and diet-associated metabolome remodeling characterizes the aging process driven by damage accumulation
2014
The drosophila ras oncogenes: Structure and nucleotide sequence
1984
Structure of the human and murine R-ras genes, novel genes closely related to ras proto-oncogenes
1987
Purification of MPF from starfish: Identification as the H1 histone kinase p34cdc2 and a possible mechanism for its periodic activation
1989 StandoutNobel
Promoter Region of the Human Harvey ras Proto-Oncogene: Similarity to the EGF Receptor Proto-Oncogene Promoter
1985 Science
HMG CoA reductase: A negatively regulated gene with unusual promoter and 5′ untranslated regions
1984 StandoutNobel
Activation of c-Ha-ras-1 proto-oncogene by in vitro modification with a chemical carcinogen, benzo(a)pyrene diol-epoxide
1984 Nature
Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene
1986 StandoutNobel
Expression of N-myc in teratocarcinoma stem cells and mouse embryos
1985 StandoutNatureNobel
RAS proteins can induce meiosis in xenopus oocytes
1985
Microinjection of the oncogene form of the human H-ras (t-24) protein results in rapid proliferation of quiescent cells
1984
Identification of a provirally activated c-Ha-ras oncogene in an avian nephroblastoma via a novel procedure: cDNA cloning of a chimaeric viral-host transcript.
1986
LAV Revisited: Origins of the Early HIV-1 Isolates from Institut Pasteur
1991 StandoutScienceNobel
Activation of ras genes in human tumors does not affect localization, modification, or nucleotide binding properties of p21
1984
Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs
1984 Standout
The human c-Ha-ras2 is a processed pseudogene inactivated by numerous base substitutions
1984
A method to detect and characterize point mutations in transcribed genes: amplification and overexpression of the mutant c-Ki-ras allele in human tumor cells.
1985
Expression of Cellular Oncogenes in Human Malignancies
1984 Science
Phosphorylation of the RAS2 gene product by protein kinase A inhibits the activation of yeast adenylyl cyclase.
1988
Human N-myc gene contributes to neoplastic transformation of mammalian cells in culture
1985 StandoutNatureNobel
rab3 is a small GTP-binding protein exclusively localized to synaptic vesicles.
1990 StandoutNobel
Works of Ursula Edman being referenced
Lifespan extension by dietary restriction is not linked to protection against somatic DNA damage in Drosophila melanogaster
2009
Activation of Ki-ras2 gene in human colon and lung carcinomas by two different point mutations
1983 Nature
Molecular cloning of mouse pancreatic islet R-cadherin: differential expression in endocrine and exocrine tissue.
1993
Isolation and expression of the Pneumocystis carinii thymidylate synthase gene.
1989