Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Suppression of Oxidative Stress by β-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor
2012 Science
Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids
2013
Aerobic glycolysis promotes T helper 1 cell differentiation through an epigenetic mechanism
2016 Science
Acetyl-CoA Metabolism Supports Multistep Pancreatic Tumorigenesis
2019
Trained immunity: A program of innate immune memory in health and disease
2016 StandoutScience
Serine Catabolism Regulates Mitochondrial Redox Control during Hypoxia
2014
Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation
2016
ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch
2016
SRC-2 Is an Essential Coactivator for Orchestrating Metabolism and Circadian Rhythm
2014
Inhibition of Mitochondrial Aconitase by Succination in Fumarate Hydratase Deficiency
2013
Cancer-associated Isocitrate Dehydrogenase Mutations Inactivate NADPH-dependent Reductive Carboxylation
2012
Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia
2011 Nature
The rate of glycolysis quantitatively mediates specific histone acetylation sites
2015
Proteomic analysis of Nrf2 deficient transgenic mice reveals cellular defence and lipid metabolism as primary Nrf2-dependent pathways in the liver
2010
Fatty Acid Labeling from Glutamine in Hypoxia Can Be Explained by Isotope Exchange without Net Reductive Isocitrate Dehydrogenase (IDH) Flux
2013
Loss of succinate dehydrogenase activity results in dependency on pyruvate carboxylation for cellular anabolism
2015
In Vivo HIF-Mediated Reductive Carboxylation Is Regulated by Citrate Levels and Sensitizes VHL-Deficient Cells to Glutamine Deprivation
2013
Loss of the SIN3 transcriptional corepressor results in aberrant mitochondrial function
2010
Mitochondria as biosynthetic factories for cancer proliferation
2015
Oxygen availability and metabolic reprogramming in cancer
2017
Hypoxia-regulated target genes implicated in tumor metastasis
2012
Oxidation of Alpha-Ketoglutarate Is Required for Reductive Carboxylation in Cancer Cells with Mitochondrial Defects
2014
PDK1-Dependent Metabolic Reprogramming Dictates Metastatic Potential in Breast Cancer
2015
The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism
2010
Histone Methyl Transferases and Demethylases; Can They Link Metabolism and Transcription?
2010
Oncometabolites: linking altered metabolism with cancer
2013
Transcriptional architecture of the mammalian circadian clock
2016 Standout
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
Glucose-Independent Glutamine Metabolism via TCA Cycling for Proliferation and Survival in B Cells
2012
AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress
2012 Nature
MYC on the Path to Cancer
2012 Standout
AMPK: guardian of metabolism and mitochondrial homeostasis
2017 Standout
Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate
2012 Standout
Genetics of Circadian Rhythms in Mammalian Model Organisms
2011
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
The Potential for Isocitrate Dehydrogenase Mutations to Produce 2-Hydroxyglutarate Depends on Allele Specificity and Subcellular Compartmentalization
2012
The action mechanisms of plant cryptochromes
2011
Metabolic Flux and the Regulation of Mammalian Cell Growth
2011
Metabolic Regulation of Epigenetics
2012
Coronaviruses Hijack the LC3-I-Positive EDEMosomes, ER-Derived Vesicles Exporting Short-Lived ERAD Regulators, for Replication
2010
The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia
2017 StandoutNobel
S-2-hydroxyglutarate regulates CD8+ T-lymphocyte fate
2016 Nature
Lipid metabolism in cancer
2012
Revisiting the TCA cycle: signaling to tumor formation
2011
The AMPK signalling pathway coordinates cell growth, autophagy and metabolism
2011 Standout
Dysregulated mTORC1 renders cells critically dependent on desaturated lipids for survival under tumor-like stress
2013
SCFFBXL3 ubiquitin ligase targets cryptochromes at their cofactor pocket
2013 Nature
Glutamine and cancer: cell biology, physiology, and clinical opportunities
2013
Hallmarks of aging: An expanding universe
2023 Standout
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
The Warburg Effect Dictates the Mechanism of Butyrate-Mediated Histone Acetylation and Cell Proliferation
2012
Acetate Dependence of Tumors
2014
Fasting, Circadian Rhythms, and Time-Restricted Feeding in Healthy Lifespan
2016
Cancer-associated 2-oxoglutarate analogues modify histone methylation by inhibiting histone lysine demethylases
2018
The multifaceted roles of fatty acid synthesis in cancer
2016
Gene Model 129 (Gm129) Encodes a Novel Transcriptional Repressor That Modulates Circadian Gene Expression
2014 StandoutNobel
Hypoxia-Inducible Factors: Master Regulators of Cancer Progression
2016 StandoutNobel
A novel method for autophagy detection in primary cells
2012
Links between metabolism and cancer
2012
Competing E3 Ubiquitin Ligases Govern Circadian Periodicity by Degradation of CRY in Nucleus and Cytoplasm
2013
Sirtuins, Aging, and Metabolism
2011
Acetyl Coenzyme A: A Central Metabolite and Second Messenger
2015
Overexpression of isocitrate dehydrogenase mutant proteins renders glioma cells more sensitive to radiation
2012
Cellular Metabolic Stress: Considering How Cells Respond to Nutrient Excess
2010
Glutamine Oxidation Maintains the TCA Cycle and Cell Survival during Impaired Mitochondrial Pyruvate Transport
2014
The nexus of chromatin regulation and intermediary metabolism
2013 Nature
Cellular Metabolism and Disease: What Do Metabolic Outliers Teach Us?
2012
Mitochondria: In Sickness and in Health
2012 Standout
Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes
2015 StandoutNobel
What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
2013 StandoutNobel
Hypoxia drives glucose transporter 3 expression through hypoxia-inducible transcription factor (HIF)–mediated induction of the long noncoding RNA NICI
2019 StandoutNobel
Reversible acetylation of PGC-1: connecting energy sensors and effectors to guarantee metabolic flexibility
2010
Regulation of Substrate Utilization by the Mitochondrial Pyruvate Carrier
2014
Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease
2016 Standout
From Krebs to clinic: glutamine metabolism to cancer therapy
2016 Standout
Acidic pH Is a Metabolic Switch for 2-Hydroxyglutarate Generation and Signaling
2016
Metabolic tinkering by the gut microbiome
2014
Acetyl-CoA Induces Cell Growth and Proliferation by Promoting the Acetylation of Histones at Growth Genes
2011
Formation of Arabidopsis Cryptochrome 2 Photobodies in Mammalian Nuclei
2013 StandoutNobel
Tracing Compartmentalized NADPH Metabolism in the Cytosol and Mitochondria of Mammalian Cells
2014
Famine versus feast: understanding the metabolism of tumors in vivo
2015
Rethinking the Regulation of Cellular Metabolism
2011
L-2-Hydroxyglutarate production arises from noncanonical enzyme function at acidic pH
2017
Interaction of Circadian Clock Proteins CRY1 and PER2 Is Modulated by Zinc Binding and Disulfide Bond Formation
2014
Hypoxia-Mediated Increases in l -2-hydroxyglutarate Coordinate the Metabolic Response to Reductive Stress
2015
Metaboloepigenetics: Interrelationships between energy metabolism and epigenetic control of gene expression
2012
A Mitochondrial RNAi Screen Defines Cellular Bioenergetic Determinants and Identifies an Adenylate Kinase as a Key Regulator of ATP Levels
2014
IDH mutation impairs histone demethylation and results in a block to cell differentiation
2012 Nature
Understanding Metabolic Regulation and Its Influence on Cell Physiology
2013
Structures of Drosophila Cryptochrome and Mouse Cryptochrome1 Provide Insight into Circadian Function
2013
Circadian topology of metabolism
2012 Nature
From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites
2016 Standout
Recent progress in the biology and physiology of sirtuins
2009 Nature
Metabolomics: beyond biomarkers and towards mechanisms
2016 Standout
Metabolic requirements for the maintenance of self-renewing stem cells
2014
Mechanism of Photosignaling by Drosophila Cryptochrome
2013 StandoutNobel
Metabolic control of TH17 and induced Treg cell balance by an epigenetic mechanism
2017 Nature
Cellular Fatty Acid Metabolism and Cancer
2013 Standout
The Emerging Hallmarks of Cancer Metabolism
2016 Standout
Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β
2012 Nature
The Nrf2 regulatory network provides an interface between redox and intermediary metabolism
2014 Standout
ATF4 Regulates MYC-Mediated Neuroblastoma Cell Death upon Glutamine Deprivation
2012
Spatiotemporal Control of Acetyl-CoA Metabolism in Chromatin Regulation
2017
Timing to Perfection: The Biology of Central and Peripheral Circadian Clocks
2012
Crosstalk between Components of Circadian and Metabolic Cycles in Mammals
2011
Clocks, Metabolism, and the Epigenome
2012
Methionine Adenosyltransferase II Serves as a Transcriptional Corepressor of Maf Oncoprotein
2011
A two-way street: reciprocal regulation of metabolism and signalling
2012
Glutamine addiction: a new therapeutic target in cancer
2010
Lipids Reprogram Metabolism to Become a Major Carbon Source for Histone Acetylation
2016
Cryptochromes mediate rhythmic repression of the glucocorticoid receptor
2011 Nature
AKT/PKB Signaling: Navigating the Network
2017 Standout
TCA Cycle and Mitochondrial Membrane Potential Are Necessary for Diverse Biological Functions
2015
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Acetyl-CoA and the regulation of metabolism: mechanisms and consequences
2015
Caloric restriction mimetics: towards a molecular definition
2014
Acetyl-CoA promotes glioblastoma cell adhesion and migration through Ca2+–NFAT signaling
2018
The Warburg Effect: How Does it Benefit Cancer Cells?
2016 Standout
Mitochondrial TCA cycle metabolites control physiology and disease
2020 Standout
The Hallmarks of Aging
2013 Standout
Induction of sarcomas by mutant IDH2
2013
MYC-induced reprogramming of glutamine catabolism supports optimal virus replication
2015
FBXL21 Regulates Oscillation of the Circadian Clock through Ubiquitination and Stabilization of Cryptochromes
2013
The epigenetics of aging and neurodegeneration
2015
Metformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent Biosynthesis
2015
Hypoxia Induces Production of L-2-Hydroxyglutarate
2015
Autophagy
2012
Quantitative Dynamics of the Link between Cellular Metabolism and Histone Acetylation
2013
Clock-Talk: Interactions between Central and Peripheral Circadian Oscillators in Mammals
2015
EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection
2016 StandoutNobel
AMPK: a nutrient and energy sensor that maintains energy homeostasis
2012 Standout
Targeting mitochondria metabolism for cancer therapy
2014
Reductive glutamine metabolism is a function of the α-ketoglutarate to citrate ratio in cells
2013
Autophagy in immunity and inflammation
2011 StandoutNature
Mechanisms and Implications of Metabolic Heterogeneity in Cancer
2019
Hypoxic Regulation of Glutamine Metabolism through HIF1 and SIAH2 Supports Lipid Synthesis that Is Necessary for Tumor Growth
2014
Oncometabolite D-2-Hydroxyglurate Directly Induces Epithelial-Mesenchymal Transition and is Associated with Distant Metastasis in Colorectal Cancer
2016
The Cryptochrome Blue Light Receptors
2010
Regulation of PGC-1α, a nodal regulator of mitochondrial biogenesis
2011
Effects of hypoxia and HIFs on cancer metabolism
2012
Glycolysis-Mediated Changes in Acetyl-CoA and Histone Acetylation Control the Early Differentiation of Embryonic Stem Cells
2015
Molecular regulation of effector and memory T cell differentiation
2014
How cancer metabolism is tuned for proliferation and vulnerable to disruption
2012 Nature
Reverse TCA cycle flux through isocitrate dehydrogenases 1 and 2 is required for lipogenesis in hypoxic melanoma cells
2012
Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC
2012
Molecular basis for the differential use of glucose and glutamine in cell proliferation as revealed by synchronized HeLa cells
2011
Hominoid-specific enzyme GLUD2 promotes growth of IDH1 R132H glioma
2014
Serine Deprivation Enhances Antineoplastic Activity of Biguanides
2014
Regulation of mammalian nucleotide metabolism and biosynthesis
2015
Altered Histone Acetylation Is Associated with Age-Dependent Memory Impairment in Mice
2010 Science
Fundamentals of cancer metabolism
2016 Standout
On Acetyl-CoA as a Gauge of Cellular Metabolic State
2011
Metabolic and Nontranscriptional Circadian Clocks: Eukaryotes
2014
Cancer Cell Metabolism: One Hallmark, Many Faces
2012
Intracellular Crotonyl-CoA Stimulates Transcription through p300-Catalyzed Histone Crotonylation
2015
Emerging Models for the Molecular Basis of Mammalian Circadian Timing
2014
Mice carrying a human GLUD2 gene recapitulate aspects of human transcriptome and metabolome development
2016 StandoutNobel
Pyruvate carboxylase is critical for non–small-cell lung cancer proliferation
2015
Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism
2016
Oxygen Sensing, Hypoxia-Inducible Factors, and Disease Pathophysiology
2013 StandoutNobel
Spermidine in health and disease
2018 StandoutScience
Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals
2022 StandoutScienceNobel
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
Central and Peripheral Circadian Clocks in Mammals
2012 Standout
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Metabolic reprogramming and cancer progression
2020 StandoutScience
Cancer Genome Landscapes
2013 StandoutScience
Circadian alignment of early onset caloric restriction promotes longevity in male C57BL/6J mice
2022 Science
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
Fueling Immunity: Insights into Metabolism and Lymphocyte Function
2013 Science
Metabolic Regulation of Immune Responses
2014
Connecting Threads: Epigenetics and Metabolism
2012
ATP-citrate lyase is essential for macrophage inflammatory response
2013
Hypoxic retinal Müller cells promote vascular permeability by HIF-1–dependent up-regulation of angiopoietin-like 4
2013 StandoutNobel
Interactive Features of Proteins Composing Eukaryotic Circadian Clocks
2014
Metabolism and the Circadian Clock Converge
2013
Time of feeding and the intrinsic circadian clock drive rhythms in hepatic gene expression
2009
Compensatory glutamine metabolism promotes glioblastoma resistance to mTOR inhibitor treatment
2015
Inflammation and metabolism in tissue repair and regeneration
2017 StandoutScience
Circadian Integration of Metabolism and Energetics
2010 Science
Chromatin landscape and circadian dynamics: Spatial and temporal organization of clock transcription
2014
Glutamine-based PET imaging facilitates enhanced metabolic evaluation of gliomas in vivo
2015
Works of Uma M. Sachdeva being referenced
ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation
2009 StandoutScience
AMPK Regulates the Circadian Clock by Cryptochrome Phosphorylation and Degradation
2009 Science
Diurnal rhythms of autophagy: Implications for cell biology and human disease
2008
Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability
2011