Citation Impact
Citing Papers
Improvement of comparative model accuracy by free-energy optimization along principal components of natural structural variation
2004 StandoutNobel
Transforming Growth Factor-β Signaling–Deficient Fibroblasts Enhance Hepatocyte Growth Factor Signaling in Mammary Carcinoma Cells to Promote Scattering and Invasion
2008
Rac and Cdc42 play distinct roles in regulating PI(3,4,5)P3 and polarity during neutrophil chemotaxis
2003
Targeted cell killing by reconstituted caspases
2007 StandoutNobel
Presenilin/γ-secretase-dependent processing of β-amyloid precursor protein regulates EGF receptor expression
2007
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
2010 StandoutNobel
Elevated myeloid-derived suppressor cells in pancreatic, esophageal and gastric cancer are an independent prognostic factor and are associated with significant elevation of the Th2 cytokine interleukin-13
2011
Maintaining the Immunological Balance in Parasitic Infections: A Role for TGF-β?
2000
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
2008 StandoutNature
ErbB-targeted therapeutic approaches in human cancer
2003
Chapter 2 PI3K/PTEN Signaling in Angiogenesis and Tumorigenesis
2009
Inflammation and cancer
2002 StandoutNature
Transforming growth factor‐β suppresses interferon‐γ‐induced toxoplasmastatic activity in murine macrophages by inhibition of tumour necrosis factor‐α production
2001
Growth Dominance of the Metastatic Cancer Cell: Cellular and Molecular Aspects
1990
Genetic Alterations of Phosphoinositide 3‐kinase Subunit Genes in Human Glioblastomas
2004
Inflammation and metabolic disorders
2006 StandoutNature
Transforming growth factor-β controls T helper type 1 cell development through regulation of natural killer cell interferon-γ
2005
Torso receptor activity is regulated by a diffusible ligand produced at the extracellular terminal regions of the Drosophila egg
1992 StandoutNobel
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Epigenetics in human disease and prospects for epigenetic therapy
2004 StandoutNature
Calmodulin-mediated Activation of Akt Regulates Survival of c-Myc-overexpressing Mouse Mammary Carcinoma Cells
2004
Wound repair and regeneration
2008 StandoutNature
TGF-beta receptor-activated p38 MAP kinase mediates Smad-independent TGF-beta responses
2002
Dermatologist-level classification of skin cancer with deep neural networks
2017 StandoutNature
Cell-Cell Contacts Prevent Anoikis in Primary Human Colonic Epithelial Cells
2006
Alternative RNA splicing in the nervous system
2001
Smad-dependent and Smad-independent pathways in TGF-β family signalling
2003 StandoutNature
Coordinated regulation of myeloid cells by tumours
2012 Standout
Involvement of chemokine receptors in breast cancer metastasis
2001 StandoutNature
New insights into the mechanisms of epithelial–mesenchymal transition and implications for cancer
2018 Standout
NF-κB inhibition delays DNA damage–induced senescence and aging in mice
2012
Transforming Growth Factor-β Differentially Inhibits MyD88-dependent, but Not TRAM- and TRIF-dependent, Lipopolysaccharide-induced TLR4 Signaling
2004
Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats
2011 StandoutNatureNobel
Transforming growth factor-β induces development of the TH17 lineage
2006 StandoutNature
Model Predicting Survival in Stage I Melanoma Based on Tumor Progression
1989 Standout
Design of biologically active binary protein 2D materials
2021 StandoutNatureNobel
Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis
2006
Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice
2008
Transforming Growth Factor-α Prevents Detachment-induced Inhibition of c-Src Kinase Activity, Bcl-XLDown-regulation, and Apoptosis of Intestinal Epithelial Cells
2001
The Drosophila gene tailless is expressed at the embryonic termini and is a member of the steroid receptor superfamily
1990 StandoutNobel
Overexpression of PDGF-BB decreases colorectal and pancreatic cancer growth by increasing tumor pericyte content
2007
Chromatin Modification, Leukaemia and Implications for Therapy
2002
Chronic immune activation and inflammation in the pathogenesis of aids and cancer
2002
Nerve growth factor induces a gene homologous to the glucocorticoid receptor gene
1988
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Tumor Angiogenesis and Metastasis — Correlation in Invasive Breast Carcinoma
1991 Standout
Paracrine and autocrine growth mechanisms in tumor metastasis to specific sites with particular emphasis on brain and lung metastasis
1993
Enhanced tumor-forming capacity for immortalized melanocytes expressing melanoma growth stimulatory activity/growth-regulated cytokine β and γ proteins
1997
Neuronal polarity: from extracellular signals to intracellular mechanisms
2007
The CD19-CR2-TAPA-1 complex, CD45 and signaling by the antigen receptor of B lymphocytes
1993
Translational activation of the lck proto-oncogene
1988 StandoutNatureNobel
The Hallmarks of Aging
2013 Standout
Bispecific Designed Ankyrin Repeat Proteins (DARPins) Targeting Epidermal Growth Factor Receptor Inhibit A431 Cell Proliferation and Receptor Recycling
2011
Immunotherapy for pancreatic cancer — science driving clinical progress
2005
Cancer-related inflammation
2008 StandoutNature
Molecular mechanisms and clinical applications of angiogenesis
2011 StandoutNature
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
2009 StandoutNature
A decade of caspases
2003
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non–Small-Cell Lung Cancer to Gefitinib
2004 Standout
Cytokine expression profile in human pancreatic carcinoma cells and in surgical specimens: implications for survival
2005
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
1993 StandoutNature
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
2010 StandoutNobel
Negative regulation of activation-induced cytidine deaminase in B cells
2006 StandoutNobel
Transforming growth factor β1 inhibits expression of NKp30 and NKG2D receptors: Consequences for the NK-mediated killing of dendritic cells
2003
Sequences of the 5′ portion of the humanc-sisgene: characterization of the transcriptional promoter and regulation of expression of the protein product by 5' untranslated mRNA sequences
1987
Increased Survival, Proliferation, and Migration in Metastatic Human Pancreatic Tumor Cells Expressing Functional CXCR4
2004
Tumor Metabolism of Lactate: The Influence and Therapeutic Potential for MCT and CD147 Regulation
2009
Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome
2006 StandoutScience
Cell Migration: Integrating Signals from Front to Back
2003 StandoutScience
Binding of Hepatitis C Virus to CD81
1998 StandoutScienceNobel
Combination antibody treatment down-regulates epidermal growth factor receptor by inhibiting endosomal recycling
2010
Integrins: Versatility, modulation, and signaling in cell adhesion
1992 Standout
One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA
2021 StandoutNobel
Laminin-binding integrin alpha 7 beta 1: functional characterization and expression in normal and malignant melanocytes.
1991
Elevated TGF-β1 Secretion and Down-Modulation of NKG2D Underlies Impaired NK Cytotoxicity in Cancer Patients
2004
Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion
2011 StandoutScience
Chemo-physical Strategies to Advance the in Vivo Functionality of Targeted Nanomedicine: The Next Generation
2020
Transforming Growth Factor-β and the Immune Response: Implications for Anticancer Therapy
2007
Interferon-α/β inhibition of interleukin 12 and interferon-γ productionin vitroand endogenously during viral infection
1997
Pharmacodynamic Studies of the Epidermal Growth Factor Receptor Inhibitor ZD1839 in Skin From Cancer Patients: Histopathologic and Molecular Consequences of Receptor Inhibition
2002
Regulation of Caenorhabditis elegans neuronal polarity by heterochronic genes
2019 StandoutNobel
Transforming growth factor-beta 1 (TGF-beta1) promotes IL-2 mRNA expression through the up-regulation of NF-kappaB, AP-1 and NF-AT in EL4 cells.
1998
Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients
2003 StandoutNobel
Inhibition of Tyrosine Kinase Activity of the Epidermal Growth Factor (EGF) Receptor by a Truncated Receptor Form That Binds to EGF: Role for Interreceptor Interaction in Kinase Regulation
1989
The intriguing role of polymorphonuclear neutrophils in antitumor reactions
2001
Molecular Basis of Tumor Progression: Mechanisms of Organ‐Specific Tumor Metastasis
1993
Epidermal growth factor and insulin stimulate nuclear pore-mediated macromolecular transport in isolated rat liver nuclei
1987
Does the Immune System See Tumors as Foreign or Self?
2003
Identification of simple arylfluorosulfates as potent agents against resistant bacteria
2021 StandoutNobel
Cancer Genome Landscapes
2013 StandoutScience
Honokiol: A Review of Its Anticancer Potential and Mechanisms
2019
Microinjection of a protein-tyrosine-phosphatase inhibits insulin action in Xenopus oocytes.
1990 StandoutNobel
Snail family members and cell survival in physiological and pathological cleft palates
2003
Principles of Allosteric Interactions in Cell Signaling
2014
TRANSFORMING GROWTH FACTOR-β REGULATION OF IMMUNE RESPONSES
2005 Standout
The epithelial mesenchymal transition confers resistance to the apoptotic effects of transforming growth factor Beta in fetal rat hepatocytes.
2002
Characterization of novel complexes on the cell surface between integrins and proteins with 4 transmembrane domains (TM4 proteins).
1996
The structure of the inter-SH2 domain of class IA phosphoinositide 3-kinase determined by site-directed spin labeling EPR and homology modeling
2003
Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
2008 StandoutNobel
Scanning the human proteome for calmodulin-binding proteins
2005 StandoutNobel
Smad3 Is Essential for TGF-β1 to Suppress IL-2 Production and TCR-Induced Proliferation, but Not IL-2-Induced Proliferation
2004
Antiapoptotic Role of PPARβ in Keratinocytes via Transcriptional Control of the Akt1 Signaling Pathway
2002
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
NATURAL KILLER CELLS IN ANTIVIRAL DEFENSE: Function and Regulation by Innate Cytokines
1999 Standout
Transforming Growth Factor β Production Is Inversely Correlated with Severity of Murine Malaria Infection
1998
Works of Ulrich Rodeck being referenced
Mutant BRAF and MEK Inhibitors Regulate the Tumor Immune Microenvironment via Pyroptosis
2019
Epidermal Growth Factor Receptor-dependent Control of Keratinocyte Survival and Bcl-xL Expression through a MEK-dependent Pathway
2001
Tumor growth modulation by a monoclonal antibody to the epidermal growth factor receptor: immunologically mediated and effector cell-independent effects.
1987
Metastatic but not primary melanoma cell lines grow in vitro independently of exogenous growth factors
1987
Differential expression and subcellular distribution of the mouse metastasis-associated proteins Mta1 and Mta3
2001
Small GTPases and tyrosine kinases coregulate a molecular switch in the phosphoinositide 3-kinase regulatory subunit
2002
Cell autonomous expression of inflammatory genes in biologically aged fibroblasts associated with elevated NF-kappaB activity
2008
Tumor-Associated Transforming Growth Factor-β and Interleukin-10 Contribute to a Systemic Th2 Immune Phenotype in Pancreatic Carcinoma Patients
1999
Growth factors in melanoma
1991
Expression and transcriptional regulation of caspase-14 in simple and complex epithelia
2002
Inhibition of Metastases of a Human Melanoma Xenograft by Monoclonal Antibody to the GD2/GD3 Gangliosides
1989
A Central Role of Bcl-XL in the Regulation of Keratinocyte Survival by Autocrine EGFR Ligands
1999
Growth-Regulatory Factors for Normal, Premalignant, and Malignant Human Cells In Vitro
1990
Human pancreatic carcinoma cells secrete bioactive interleukin-18 after treatment with 5-fluorouracil: Implications for anti-tumor immune response
2005
Regulation of Bcl-xLexpression in human keratinocytes by cell–substratum adhesion and the epidermal growth factor receptor
1997
Matrix-independent Survival of Human Keratinocytes through an EGF Receptor/MAPK-Kinase-dependent Pathway
2001
Biology of tumor progression in human melanocytes.
1987
Presence of tumor-associated antigens in epidermal growth factor receptors from different human carcinomas.
1987
Transforming Growth Factor β Enhances Epithelial Cell Survival via Akt-dependent Regulation of FKHRL1
2001
Targeting the epidermal growth factor receptor in cancer: apoptosis takes center stage.
2003
Binding of an antagonistic monoclonal antibody to an intact and fragmented EGF-receptor polypeptide
1987
The EGF receptor - an essential regulator of multiple epidermal functions.
2000
Chromatin binding of epidermal growth factor, nerve growth factor, and platelet-derived growth factor in cells bearing the appropriate surface receptors.
1986
Production and pro-apoptotic activity of soluble CD95 ligand in pancreatic carcinoma.
2000
Melanoma-associated expression of transforming growth factor-beta isoforms.
1996
Cooperative Induction of a Tolerogenic Dendritic Cell Phenotype by Cytokines Secreted by Pancreatic Carcinoma Cells
2006
Mechanism for elimination of a tumor suppressor: Aberrant splicing of a brain-specific exon causes loss of function of Bin1 in melanoma
1999
Regulation of intracellular pH in human melanoma: potential therapeutic implications.
2002
Human melanoma cell lines of primary and metastatic origin express the genes encoding the chains of platelet-derived growth factor (PDGF) and produce a PDGF-like growth factor.
1986
Resistance of Akt kinases to dephosphorylation through ATP-dependent conformational plasticity
2011
Molecular cloning of cDNA for the human tumor-associated antigen CO-029 and identification of related transmembrane antigens.
1990
Enhanced EGFR inhibition and distinct epitope recognition by EGFR antagonistic MABS C225 and 425
2008
Development of invasive and growth factor-independent cell variants from primary human melanomas.
1991
Regulation of NK cell functions by TGF-beta 1.
1995
Complex Regulation of Signal Transducers and Activators of Transcription 3 Activation in Normal and Malignant Keratinocytes
2004