Uli Binder

Switchable Cas9

De novo design of immunoglobulin-like domains

Hydrophobic mismatch drives self-organization of designer proteins into synthetic membranes

Myeloid-derived suppressor cells in the era of increasing myeloid cell diversity

The unfolded protein response and gastrointestinal disease

Reactive oxygen species (ROS) as pleiotropic physiological signalling agents

Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites

Treatment of diet-induced lipodystrophic C57BL/6J mice with long-acting PASylated leptin normalises insulin sensitivity and hepatic steatosis by promoting lipid utilisation

Bridge helix arginines play a critical role in Cas9 sensitivity to mismatches

De novo design of a fluorescence-activating β-barrel

Emerging Strategies for Developing Next-Generation Protein Therapeutics for Cancer Treatment

Ulcerative colitis

Polymer therapeutics: Top 10 selling pharmaceuticals — What next?

Nanoparticle-Based Medicines: A Review of FDA-Approved Materials and Clinical Trials to Date

The Emerging Roles of Endoplasmic Reticulum Stress in Balancing Immunity and Tolerance in Health and Diseases: Mechanisms and Opportunities

STING agonist delivery by tumour-penetrating PEG-lipid nanodiscs primes robust anticancer immunity

Endoplasmic Reticulum Stress and Oxidative Stress in Cell Fate Decision and Human Disease

Anticalins: Exploiting a non‐Ig scaffold with hypervariable loops for the engineering of binding proteins

Mechanisms of Insulin Action and Insulin Resistance

The Current State of Peptide Drug Discovery: Back to the Future?

The Chemistry of Reactive Oxygen Species (ROS) Revisited: Outlining Their Role in Biological Macromolecules (DNA, Lipids and Proteins) and Induced Pathologies

Reactive Oxygen Species in Metabolic and Inflammatory Signaling

Engineering of temperature- and light-switchable Cas9 variants

PASylation: a biological alternative to PEGylation for extending the plasma half-life of pharmaceutically active proteins

High-throughput Sorting of an Anticalin Library via EspP-mediated Functional Display on the Escherichia coli Cell Surface

Endoplasmic Reticulum Stress Response Promotes Cytotoxic Phenotype of CD8αβ+ Intraepithelial Lymphocytes in a Mouse Model for Crohn’s Disease-like Ileitis